Experts and Doctors on methanosarcina in University Park, Florida, United States

Summary

Locale: University Park, Florida, United States
Topic: methanosarcina

Top Publications

  1. Maupin Furlow J, Ferry J. A proteasome from the methanogenic archaeon Methanosarcina thermophila. J Biol Chem. 1995;270:28617-22 pubmed
    ..The results suggest that proteasomes are more widespread in the Archaea than previously proposed. Southern blotting experiments suggested the presence of ubiquitin-like sequences in M. thermophila. ..
  2. Rasche M, Smith K, Ferry J. Identification of cysteine and arginine residues essential for the phosphotransacetylase from Methanosarcina thermophila. J Bacteriol. 1997;179:7712-7 pubmed
    ..Five arginines were individually replaced with glutamine. Kinetic analysis of the altered enzymes identified R310 as essential for activity. Of the four nonessential for activity, R87 and R133 appear to be involved in binding CoA...
  3. Borup B, Ferry J. O-Acetylserine sulfhydrylase from Methanosarcina thermophila. J Bacteriol. 2000;182:45-50 pubmed
    ..The results also provide the first biochemical evidence for an enzyme with the potential for involvement in cysteine biosynthesis in the Archaea...
  4. Lessner D, Ferry J. The archaeon Methanosarcina acetivorans contains a protein disulfide reductase with an iron-sulfur cluster. J Bacteriol. 2007;189:7475-84 pubmed publisher
  5. Reichlen M, Murakami K, Ferry J. Functional analysis of the three TATA binding protein homologs in Methanosarcina acetivorans. J Bacteriol. 2010;192:1511-7 pubmed publisher
    ..Together, the results suggest that TBP2 and TBP3 are required for efficient growth under conditions similar to the conditions in the native environment of M. acetivorans...
  6. Satish Kumar V, Ferry J, Maranas C. Metabolic reconstruction of the archaeon methanogen Methanosarcina Acetivorans. BMC Syst Biol. 2011;5:28 pubmed publisher
    ..acetivorans. This process relies on previously developed computational tools developed in our group to correct growth prediction inconsistencies with in vivo data sets and rectify topological inconsistencies in the model...
  7. Steinberg L, Regan J. Response of lab-scale methanogenic reactors inoculated from different sources to organic loading rate shocks. Bioresour Technol. 2011;102:8790-8 pubmed publisher
    ..Although the resultant communities required base addition, an increase in Methanosarcina numbers after glucose pulses resulted in decreased acetate and increased reactor pH and methane production. ..
  8. Reichlen M, Vepachedu V, Murakami K, Ferry J. MreA functions in the global regulation of methanogenic pathways in Methanosarcina acetivorans. MBio. 2012;3:e00189-12 pubmed publisher
    ..Finally, the results contribute to a broader understanding of transcriptional regulation in the domain Archaea...
  9. Maupin Furlow J, Ferry J. Characterization of the cdhD and cdhE genes encoding subunits of the corrinoid/iron-sulfur enzyme of the CO dehydrogenase complex from Methanosarcina thermophila. J Bacteriol. 1996;178:340-6 pubmed
    ..The purified CdhE protein exhibited an Fe-S center and base-off cobalamin binding in which the benzimidazole base nitrogen atom was no longer a lower axial ligand to the cobalt atom...

More Information

Publications15

  1. Maupin Furlow J, Ferry J. Analysis of the CO dehydrogenase/acetyl-coenzyme A synthase operon of Methanosarcina thermophila. J Bacteriol. 1996;178:6849-56 pubmed
    ..thermophila. The deduced protein sequence of ORF1, located between the cdhC and cdhD genes, has 29% identity to NifH2 from Methanobacterium ivanovii...
  2. Borup B, Ferry J. Cysteine biosynthesis in the Archaea: Methanosarcina thermophila utilizes O-acetylserine sulfhydrylase. FEMS Microbiol Lett. 2000;189:205-10 pubmed
    ..When M. thermophila is grown with cysteine as the sole sulfur source, O-acetylserine sulfhydrylase activity is maximally expressed suggesting alternative roles for this enzyme apart from cysteine biosynthesis...
  3. Smith K, Ferry J. Prokaryotic carbonic anhydrases. FEMS Microbiol Rev. 2000;24:335-66 pubmed
    ..Investigations into prokaryotic carbonic anhydrase have already led to the identification of a new class (gamma) and future research will undoubtedly reveal novel functions for carbonic anhydrase in prokaryotes. ..
  4. Iyer P, Lawrence S, Luther K, Rajashankar K, Yennawar H, Ferry J, et al. Crystal structure of phosphotransacetylase from the methanogenic archaeon Methanosarcina thermophila. Structure. 2004;12:559-67 pubmed publisher
    ..A search for structural homologs revealed the NADP(+)-dependent isocitrate and isopropylmalate dehydrogenases as the only homologs with a similar two-domain architecture...
  5. Lessner D, Li L, Li Q, Rejtar T, Andreev V, Reichlen M, et al. An unconventional pathway for reduction of CO2 to methane in CO-grown Methanosarcina acetivorans revealed by proteomics. Proc Natl Acad Sci U S A. 2006;103:17921-6 pubmed
    ..Finally, the pathway supports the basis for a recently proposed primitive CO-dependent energy-conservation cycle that drove and directed the early evolution of life on Earth...
  6. Ferry J, Lessner D. Methanogenesis in marine sediments. Ann N Y Acad Sci. 2008;1125:147-57 pubmed publisher
    ..acetivorans. The differences in both pathways reflect an adaptation by M. acetivorans to the marine environment...