Experts and Doctors on inbred f344 rats in Miami, Florida, United States


Locale: Miami, Florida, United States
Topic: inbred f344 rats

Top Publications

  1. Neary J, Shi Y, Kang Y, Tran M. Opposing effects of P2X(7) and P2Y purine/pyrimidine-preferring receptors on proliferation of astrocytes induced by fibroblast growth factor-2: implications for CNS development, injury, and repair. J Neurosci Res. 2008;86:3096-105 pubmed publisher
    ..These trophic actions of P2X(7) and P2Y purine/pyrimidine receptors may contribute to the regulation of CNS development, adult neurogenesis, and the response of astrocytes to injury. ..
  2. Auais A, Wedde Beer K, Piedimonte G. Anti-inflammatory effect of albuterol enantiomers during respiratory syncytial virus infection in rats. Pediatr Pulmonol. 2005;40:228-34 pubmed
    ..Based on these data, we speculate that (R)-albuterol may be more effective than other adrenergic agents in the management of bronchiolitis...
  3. Rama Rao K, Jayakumar A, Tong X, Curtis K, Norenberg M. Brain aquaporin-4 in experimental acute liver failure. J Neuropathol Exp Neurol. 2010;69:869-79 pubmed publisher
    ..These results indicate that increased AQP4 PM levels in perivascular astrocytic end-feet are likely critical to the development of brain edema in ALF. ..
  4. Kanashiro Takeuchi R, Tziomalos K, Takeuchi L, Treuer A, Lamirault G, Dulce R, et al. Cardioprotective effects of growth hormone-releasing hormone agonist after myocardial infarction. Proc Natl Acad Sci U S A. 2010;107:2604-9 pubmed publisher
    ..The phenotypic profile of the response to a potent GHRH agonist has therapeutic implications. ..
  5. Grumbles R, Sesodia S, Wood P, Thomas C. Neurotrophic factors improve motoneuron survival and function of muscle reinnervated by embryonic neurons. J Neuropathol Exp Neurol. 2009;68:736-46 pubmed publisher
    ..Thus, immediate application of a specific combination of factors to dissociated embryonic neurons improves survival of motoneurons and the long-term function of reinnervated muscle. ..
  6. Hu C, Wedde Beer K, Auais A, Rodriguez M, Piedimonte G. Nerve growth factor and nerve growth factor receptors in respiratory syncytial virus-infected lungs. Am J Physiol Lung Cell Mol Physiol. 2002;283:L494-502 pubmed
    ..These data indicate that expression of NGF and its receptors in the lungs declines physiologically with age but is upregulated by RSV and is a major determinant of neurogenic inflammation. ..
  7. Wedde Beer K, Hu C, Rodriguez M, Piedimonte G. Leukotrienes mediate neurogenic inflammation in lungs of young rats infected with respiratory syncytial virus. Am J Physiol Lung Cell Mol Physiol. 2002;282:L1143-50 pubmed
  8. Zhu X, Price Schiavi S, Carraway K. Extracellular regulated kinase (ERK)-dependent regulation of sialomucin complex/rat Muc4 in mammary epithelial cells. Oncogene. 2000;19:4354-61 pubmed
    ..These results suggest that expression of SMC/Muc4 in mammary epithelial cells is regulated by selected growth factors through an ERK-dependent pathway at the transcript level. ..
  9. Pearse D, Pereira F, Marcillo A, Bates M, Berrocal Y, Filbin M, et al. cAMP and Schwann cells promote axonal growth and functional recovery after spinal cord injury. Nat Med. 2004;10:610-6 pubmed
    ..These findings show that cAMP levels are key for protection, growth and myelination of injured CNS axons in vivo and recovery of function. ..

More Information


  1. Rong M, Rossi E, Zhang J, McNeer R, Van Den Brande J, Yasin M, et al. Expression and localization of Muc4/sialomucin complex (SMC) in the adult and developing rat intestine: implications for Muc4/SMC function. J Cell Physiol. 2005;202:275-84 pubmed
    ..These results suggest that membrane mucin Muc4/SMC serves different functions during development of the intestine in the rat, but is primarily a secreted product in the adult animal. ..
  2. Lomako J, Lomako W, Decker S, Carraway C, Carraway K. Non-apoptotic desquamation of cells from corneal epithelium: putative role for Muc4/sialomucin complex in cell release and survival. J Cell Physiol. 2005;202:115-24 pubmed
    ..Desquamating cells also exhibit a high level of Muc4/SMC. Since Muc4/SMC has been shown to be a potent anti-adhesive and a repressor of apoptosis, we propose that it plays a role in the non-apoptotic desquamation process. ..
  3. Zhang J, Carraway C, Carraway K. Muc4 expression during blood vessel formation in damaged rat cornea. Curr Eye Res. 2006;31:1011-4 pubmed
    ..Muc4 expression was limited at days 4-5, but extensive at days 7-10. Muc4 expression develops in endothelial cells during the mid-stages of cell aggregation and blood vessel formation. ..
  4. de Rivero Vaccari J, Marcillo A, Nonner D, Dietrich W, Keane R. Neuroprotective effects of bone morphogenetic protein 7 (BMP7) treatment after spinal cord injury. Neurosci Lett. 2009;465:226-9 pubmed publisher
    ..These studies show that BMP7 administration may be used as a therapeutic strategy to reduce the damaging excitotoxic effects following SCI. ..
  5. Perez A, Barco R, Fernandez I, Price Schiavi S, Carraway K. PEA3 transactivates the Muc4/sialomucin complex promoter in mammary epithelial and tumor cells. J Biol Chem. 2003;278:36942-52 pubmed
    ..These data suggest that expression of PEA3 in mammary tumors leads to up-regulation of Muc4/SMC transcription, the gene product of which may contribute to the metastatic potential of mammary tumors. ..
  6. Price Schiavi S, Andrechek E, Idris N, Li P, Rong M, Zhang J, et al. Expression, location, and interactions of ErbB2 and its intramembrane ligand Muc4 (sialomucin complex) in rat mammary gland during pregnancy. J Cell Physiol. 2005;203:44-53 pubmed
    ..These data provide further evidence of the ability of Muc4/SMC to interact with ErbB2 and influence its behavior in normal epithelia. ..
  7. Thomas C, Erb D, Grumbles R, Bunge R. Embryonic cord transplants in peripheral nerve restore skeletal muscle function. J Neurophysiol. 2000;84:591-5 pubmed
  8. Davis A, Lotocki G, Marcillo A, Dietrich W, Keane R. FasL, Fas, and death-inducing signaling complex (DISC) proteins are recruited to membrane rafts after spinal cord injury. J Neurotrauma. 2007;24:823-34 pubmed
    ..Thus, FasL/Fas-mediated signaling after SCI is similar to Fas expressing Type I cell apoptosis. ..
  9. de Rivero Vaccari J, Lotocki G, Marcillo A, Dietrich W, Keane R. A molecular platform in neurons regulates inflammation after spinal cord injury. J Neurosci. 2008;28:3404-14 pubmed publisher
    ..Thus, rat spinal cord neurons contain a caspase-1, pro-ILbeta, and pro-IL-18 activating complex different from the human NALP1 inflammasome that constitutes an important arm of the innate CNS inflammatory response after SCI. ..
  10. Hu Y, Carvajal M, Carraway K. Sialomucin complex (rMuc4) expression during development of the rat cornea. Curr Eye Res. 2000;21:820-3 pubmed
    ..SMC at the corneal surfaces steadily increases during development to adulthood, but does not exhibit a marked transition in expression at the time of eye-opening. ..
  11. Neary J, Kang Y. P2 purinergic receptors signal to glycogen synthase kinase-3beta in astrocytes. J Neurosci Res. 2006;84:515-24 pubmed
    ..These findings suggest that purinergic signaling contributes to the regulation of GSK3beta functions, one of which may be the response of astrocytes to CNS injury on release of ATP. ..
  12. Lomako J, Lomako W, Carothers Carraway C, Carraway K. Regulation of the membrane mucin Muc4 in corneal epithelial cells by proteosomal degradation and TGF-beta. J Cell Physiol. 2010;223:209-14 pubmed publisher