Experts and Doctors on neurodegenerative diseases in Maine, United States


Locale: Maine, United States
Topic: neurodegenerative diseases

Top Publications

  1. Lee J, Beebe K, Nangle L, Jang J, Longo Guess C, Cook S, et al. Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration. Nature. 2006;443:50-5 pubmed
    ..These findings demonstrate that disruption of translational fidelity in terminally differentiated neurons leads to the accumulation of misfolded proteins and cell death, and provide a novel mechanism underlying neurodegeneration. ..
  2. Zhu X, Libby R, de Vries W, Smith R, Wright D, Bronson R, et al. Mutations in a P-type ATPase gene cause axonal degeneration. PLoS Genet. 2012;8:e1002853 pubmed publisher
    ..Thus, our data demonstrate for the first time that mutation of a mammalian phosphatidylserine translocase causes axon degeneration and neurodegenerative disease. ..