Experts and Doctors on insect hormones in New Jersey, United States


Locale: New Jersey, United States
Topic: insect hormones

Top Publications

  1. Rose L, Wieschaus E. The Drosophila cellularization gene nullo produces a blastoderm-specific transcript whose levels respond to the nucleocytoplasmic ratio. Genes Dev. 1992;6:1255-68 pubmed
    ..The regulation of nullo RNA levels during cycle 14, however, is coupled to the nucleocytoplasmic ratio, which also controls the cessation of rapid, synchronous mitosis just before cellularization...
  2. Bopp D, Bell L, Cline T, Schedl P. Developmental distribution of female-specific Sex-lethal proteins in Drosophila melanogaster. Genes Dev. 1991;5:403-15 pubmed
    ..The onset of Sxl expression in the germ line occurs later than that in the soma. ..
  3. Samuels M, Bopp D, Colvin R, Roscigno R, Garcia Blanco M, Schedl P. RNA binding by Sxl proteins in vitro and in vivo. Mol Cell Biol. 1994;14:4975-90 pubmed
    ..After prolonged heat shock, all Sxl protein was restricted to the heat-induced puff at the hs93D locus. In contrast, a presumptive small nuclear RNP protein was observed at several heat puffs following shock. ..
  4. Neuman Silberberg F, Schupbach T. The Drosophila dorsoventral patterning gene gurken produces a dorsally localized RNA and encodes a TGF alpha-like protein. Cell. 1993;75:165-74 pubmed
    ..We propose that the dorsal localization of grk RNA results in a spatially restricted ligand that asymmetrically activates the receptor. ..
  5. Bernstein M, Lersch R, Subrahmanyan L, Cline T. Transposon insertions causing constitutive Sex-lethal activity in Drosophila melanogaster affect Sxl sex-specific transcript splicing. Genetics. 1995;139:631-48 pubmed
  6. Bhat K. The patched signaling pathway mediates repression of gooseberry allowing neuroblast specification by wingless during Drosophila neurogenesis. Development. 1996;122:2921-32 pubmed
    ..The timing of the response to Gsb suggests that the specification of neuroblast identities takes place within the neuroectoderm, prior to neuroblast delamination. ..
  7. Suter B, Steward R. Requirement for phosphorylation and localization of the Bicaudal-D protein in Drosophila oocyte differentiation. Cell. 1991;67:917-26 pubmed
  8. Bell L, Horabin J, Schedl P, Cline T. Positive autoregulation of sex-lethal by alternative splicing maintains the female determined state in Drosophila. Cell. 1991;65:229-39 pubmed
    ..We conclude that the female determined state is maintained by Sxl through positive autoregulation, while the male determined state is maintained by default. ..
  9. Riggleman B, Schedl P, Wieschaus E. Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless. Cell. 1990;63:549-60 pubmed
    ..Two other segment polarity genes, porcupine and dishevelled, are required for this effect. We also show that arm protein is closely associated with the plasma membrane in virtually all cell types and often colocalizes with F-actin. ..

More Information


  1. Peifer M, Wieschaus E. The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin. Cell. 1990;63:1167-76 pubmed
    ..We present a possible model for the cellular role of arm. ..
  2. Suter B, Romberg L, Steward R. Bicaudal-D, a Drosophila gene involved in developmental asymmetry: localized transcript accumulation in ovaries and sequence similarity to myosin heavy chain tail domains. Genes Dev. 1989;3:1957-68 pubmed
    ..The predicted protein contains several extended amphipathic helices, and its similarity to myosin heavy chain tails, paramyosin, and kinesin suggests a similar type of coiled-coil protein interaction. ..
  3. Riggleman B, Wieschaus E, Schedl P. Molecular analysis of the armadillo locus: uniformly distributed transcripts and a protein with novel internal repeats are associated with a Drosophila segment polarity gene. Genes Dev. 1989;3:96-113 pubmed
    ..Considering these results and previous genetic observations, we discuss potential roles for the arm gene in pattern formation processes. ..
  4. Roth S, Neuman Silberberg F, Barcelo G, Sch pbach T. cornichon and the EGF receptor signaling process are necessary for both anterior-posterior and dorsal-ventral pattern formation in Drosophila. Cell. 1995;81:967-78 pubmed
  5. Schupbach T, Roth S. Dorsoventral patterning in Drosophila oogenesis. Curr Opin Genet Dev. 1994;4:502-7 pubmed
    ..This localized signal from the oocyte to the follicle cells appears to initiate a cascade of events leading to dorsal follicle cell differentiation, and delimiting and orienting the future dorsoventral axis of the embryo. ..
  6. Roth S. Axis determination. Proteolytic generation of a morphogen. Curr Biol. 1994;4:755-7 pubmed
    ..Ventral activation of a transmembrane receptor, Toll, is a crucial step in dorsoventral axis establishment in Drosophila embryos. The ventral ligand for Toll seems to be a proteolytic fragment of the SpƤtzle protein. ..
  7. Gavis E. Pattern formation. Gurken meets torpedo for the first time. Curr Biol. 1995;5:1252-4 pubmed
    ..Intercellular communication between oocyte and follicle cells, mediated by the gurken-torpedo/DER signalling pathway, has a crucial role in determining both anterior-posterior and dorsal-ventral polarity in Drosophila. ..