Experts and Doctors on base sequence in California, United States


Locale: California, United States
Topic: base sequence

Top Publications

  1. Gallagher T, Escarmis C, Buchmeier M. Alteration of the pH dependence of coronavirus-induced cell fusion: effect of mutations in the spike glycoprotein. J Virol. 1991;65:1916-28 pubmed
    ..These findings demonstrate that the pH dependence of coronavirus fusion is highly variable and that this variability can be determined by as few as three amino acid residues. ..
  2. Kulesh D, Oshima R. Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells. Mol Cell Biol. 1988;8:1540-50 pubmed
  3. Fisher R, Parisi M, Clayton D. Flexible recognition of rapidly evolving promoter sequences by mitochondrial transcription factor 1. Genes Dev. 1989;3:2202-17 pubmed
    ..Flexible DNA sequence recognition by mtTF1, on the other hand, may be a principal facilitating mechanism for rapid control sequence evolution. ..
  4. DiScipio R, Hugli T. The molecular architecture of human complement component C6. J Biol Chem. 1989;264:16197-206 pubmed
    ..The combined results are discussed and comparisons made with the other late acting components of complement and perforin. ..
  5. Salvato M, Shimomaye E, Southern P, Oldstone M. Virus-lymphocyte interactions. IV. Molecular characterization of LCMV Armstrong (CTL+) small genomic segment and that of its variant, Clone 13 (CTL-). Virology. 1988;164:517-22 pubmed
    ..Further, the availability of the complete S RNA sequence for LCMV ARM and ARM Clone 13 variant allows a detailed comparison with WE (V. Romanowski et al. (1985) Virus Res. 3, 110-114), the only other LCMV S RNA so far sequenced...
  6. Torti S, Kwak E, Miller S, Miller L, Ringold G, Myambo K, et al. The molecular cloning and characterization of murine ferritin heavy chain, a tumor necrosis factor-inducible gene. J Biol Chem. 1988;263:12638-44 pubmed
    ..These findings suggest a novel role for TNF in iron metabolism. ..
  7. Patil N, Cox D, Bhat D, Faham M, Myers R, Peterson A. A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation. Nat Genet. 1995;11:126-9 pubmed
    ..The mutation alters the putative ion-permeable, pore-forming domain of the protein, suggesting that granule cell differentiation is regulated by changes in membrane permeability. ..
  8. Hollmann M, Boulter J, Maron C, Beasley L, Sullivan J, Pecht G, et al. Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor. Neuron. 1993;10:943-54 pubmed
    ..Zn2+ potentiation is mimicked by Cd2+, Cu2+, and Ni2+, but not by Mn2+, Co2+, Fe3+, Sn2+, or Hg2+. Our results suggest a possible role for Zn2+ as a positive modulator of NMDA receptors in certain regions of the brain. ..
  9. Jones B, Falkow S. Identification and characterization of a Salmonella typhimurium oxygen-regulated gene required for bacterial internalization. Infect Immun. 1994;62:3745-52 pubmed
    ..The orgA mutant was as virulent as the wild-type strain was when inoculated intraperitoneally but is significantly reduced (> 60-fold) in its ability to cause disease by an oral route of infection. ..

More Information

Publications582 found, 100 shown here

  1. Malloy P, Weisman Y, Feldman D. Hereditary 1 alpha,25-dihydroxyvitamin D-resistant rickets resulting from a mutation in the vitamin D receptor deoxyribonucleic acid-binding domain. J Clin Endocrinol Metab. 1994;78:313-6 pubmed
    ..It is unclear at this time whether these kindreds might be distantly related and, therefore, harbor the same mutation, or whether this represents a mutational hot spot in the VDR gene...
  2. Barker P, Lomen Hoerth C, Gensch E, Meakin S, Glass D, Shooter E. Tissue-specific alternative splicing generates two isoforms of the trkA receptor. J Biol Chem. 1993;268:15150-7 pubmed
    ..In rats and humans, trkAII is the only isoform expressed within neuronal tissues at appreciable levels whereas trkAI, the form of trkA originally cloned, appears to be expressed mainly in non-neuronal tissues. ..
  3. Nakayama J, Fukuda M, Hirabayashi Y, Kanamori A, Sasaki K, Nishi T, et al. Expression cloning of a human GT3 synthase. GD3 AND GT3 are synthesized by a single enzyme. J Biol Chem. 1996;271:3684-91 pubmed
    ..Taken together, these results indicate that C series polysialogangliosides are synthesized by a ganglioside-specific polysialyltransferase, GD3/GT3ST, that is specifically expressed in neural tissues. ..
  4. Christensen S, Dagenais N, Chory J, Weigel D. Regulation of auxin response by the protein kinase PINOID. Cell. 2000;100:469-78 pubmed
    ..Constitutive expression of PID causes a phenotype in both shoots and roots that is similar to that of auxin-insensitive plants, implying that PID, which encodes a serine-threonine protein kinase, negatively regulates auxin signaling. ..
  5. Xia Y, Zhang Z, Kruse U, Vogt P, Li J. The new serine-threonine kinase, Qik, is a target of the Qin oncogene. Biochem Biophys Res Commun. 2000;276:564-70 pubmed
    ..In vitro kinase tests demonstrate that Qik is capable of autophosphorylation. Elevated levels of Qik transcripts are also observed in Src-transformed cells, suggesting that Src and Qin share some targets. ..
  6. Heidelberg J, Nelson W, Schoenfeld T, Bhaya D. Germ warfare in a microbial mat community: CRISPRs provide insights into the co-evolution of host and viral genomes. PLoS ONE. 2009;4:e4169 pubmed publisher
  7. Denzel M, Scimia M, Zumstein P, Walsh K, Ruiz Lozano P, Ranscht B. T-cadherin is critical for adiponectin-mediated cardioprotection in mice. J Clin Invest. 2010;120:4342-52 pubmed publisher
    ..These data suggest that T-cadherin protects from stress-induced pathological cardiac remodeling by binding APN and activating its cardioprotective functions. ..
  8. Hsieh C, Swaroop A, Francke U. Chromosomal localization and cDNA sequence of human ralB, a GTP binding protein. Somat Cell Mol Genet. 1990;16:407-10 pubmed
    ..The RALB gene, a new member of the ra1 family, has been isolated, sequenced, and assigned to human chromosome 2 cen-q13. One other member of this family, RALA, has been previously mapped to the short arm of human chromosome 7. ..
  9. Hagihara K, Watanabe K, Chun J, Yamaguchi Y. Glypican-4 is an FGF2-binding heparan sulfate proteoglycan expressed in neural precursor cells. Dev Dyn. 2000;219:353-67 pubmed
    ..These results suggest that glypican-4 plays a critical role in the regulation of FGF2 action during cortical neurogenesis. ..
  10. Kiefer M, Schmid C, Waldvogel M, Schläpfer I, Futo E, Masiarz F, et al. Characterization of recombinant human insulin-like growth factor binding proteins 4, 5, and 6 produced in yeast. J Biol Chem. 1992;267:12692-9 pubmed
    ..The results of this study show that the primary effect of the three rhIGFBPs is the attenuation of IGF activity and suggest that IGFBPs contribute to the control of IGF-mediated cell growth and metabolism. ..
  11. Ondek B, Hardy R, Baker E, Stamnes M, Shieh B, Zuker C. Genetic dissection of cyclophilin function. Saturation mutagenesis of the Drosophila cyclophilin homolog ninaA. J Biol Chem. 1992;267:16460-6 pubmed
    ..We also show that mammalian cyclophilins engineered to contain missense mutations found in two temperature-sensitive ninaA alleles display temperature-sensitive prolyl cis/trans isomerase activity. ..
  12. Monica K, Galili N, Nourse J, Saltman D, Cleary M. PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1. Mol Cell Biol. 1991;11:6149-57 pubmed
    ..Differences in their amino and carboxy termini may modulate their activities, mediated in part by differential splicing and, for PBX1, protein fusion following t(1;19) chromosomal translocation. ..
  13. Mattox W, Baker B. Autoregulation of the splicing of transcripts from the transformer-2 gene of Drosophila. Genes Dev. 1991;5:786-96 pubmed
    ..The finding that transformer-2 controls multiple splicing decisions suggests that a variety of different alternative splicing choices could be regulated by a relatively limited number of trans-acting factors. ..
  14. Barnett M, Long S. DNA sequence and translational product of a new nodulation-regulatory locus: syrM has sequence similarity to NodD proteins. J Bacteriol. 1990;172:3695-700 pubmed
    ..Expression from this locus was confirmed by using in vitro transcription-translation assays. The open reading frame encoded a protein of either 33 or 36 kilodaltons whose sequence shows similarity to NodD regulatory proteins...
  15. Begovich A, Helmuth R, Oksenberg J, Sakai K, Tabira T, Sasazuki T, et al. HLA-DP beta and susceptibility to multiple sclerosis: an analysis of caucasoid and Japanese patient populations. Hum Immunol. 1990;28:365-72 pubmed
    ..However, the results do show a dramatic difference in the allele frequencies between the two control populations, further emphasizing the need for ethnically matched controls in studies of HLA and disease. ..
  16. Garchon H, Loh E, Ho W, Amar L, Avner P, Davis M. The XLR sequence family: dispersion on the X and Y chromosomes of a large set of closely related sequences, most of which are pseudogenes. Nucleic Acids Res. 1989;17:9871-88 pubmed
  17. Gahlmann R, Troutt A, Wade R, Gunning P, Kedes L. Alternative splicing generates variants in important functional domains of human slow skeletal troponin T. J Biol Chem. 1987;262:16122-6 pubmed
    ..This unusual familial trait is not known in any other muscle or nonmuscle multigene family. ..
  18. Erba H, Eddy R, Shows T, Kedes L, Gunning P. Structure, chromosome location, and expression of the human gamma-actin gene: differential evolution, location, and expression of the cytoskeletal beta- and gamma-actin genes. Mol Cell Biol. 1988;8:1775-89 pubmed
    ..Finally, we demonstrate that the human gamma-actin gene is expressed after introduction into mouse L cells and C2 myoblasts and that, upon fusion of C2 cells to form myotubes, the human gamma-actin gene is appropriately regulated. ..
  19. Reed M, Leff S. Maternal imprinting of human SNRPN, a gene deleted in Prader-Willi syndrome. Nat Genet. 1994;6:163-7 pubmed
    ..Maternal imprinting of SNRPN supports the hypothesis that paternal absence of SNRPN is responsible for the PWS phenotype. ..
  20. Heisterkamp N, Kaartinen V, van Soest S, Bokoch G, Groffen J. Human ABR encodes a protein with GAPrac activity and homology to the DBL nucleotide exchange factor domain. J Biol Chem. 1993;268:16903-6 pubmed
    ..Although both ABR and BCR have GAP activity, ABR lacks homology to the serine/threonine kinase domain of BCR. Therefore, ABR is likely to have cellular functions overlapping with but also distinct from those of BCR. ..
  21. Leatherwood J, Lopez Girona A, Russell P. Interaction of Cdc2 and Cdc18 with a fission yeast ORC2-like protein. Nature. 1996;379:360-3 pubmed
    ..These findings suggest that ORC functions are conserved among eukaryotes and provide evidence that Cdc2 controls DNA replication initiation by acting directly at chromosomal origins. ..
  22. Simske J, Kaech S, Harp S, Kim S. LET-23 receptor localization by the cell junction protein LIN-7 during C. elegans vulval induction. Cell. 1996;85:195-204 pubmed
    ..These results suggest that proper localization of LET-23 receptor to the Pn.p cell junctions is required for signaling activity. ..
  23. Takayama K, Danks D, Salazar E, Cleaver J, Weber C. DNA repair characteristics and mutations in the ERCC2 DNA repair and transcription gene in a trichothiodystrophy patient. Hum Mutat. 1997;9:519-25 pubmed
    ..Comparisons suggest that the mutation of Ala725 to Pro correlates with TTD with intermediate UV sensitivity. ..
  24. de Lecea L, Ruiz Lozano P, Danielson P, Peelle Kirley J, Foye P, Frankel W, et al. Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin. Genomics. 1997;42:499-506 pubmed
    ..The human putative cortistatin peptide has an arginine for lysine substitution, compared to the rat and mouse products, and is N-terminally extended by 3 amino acids. ..
  25. Chen C, Gherzi R, Andersen J, Gaietta G, Jurchott K, Royer H, et al. Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation. Genes Dev. 2000;14:1236-48 pubmed
    ..Nucleolin and YB-1 are required for formation of an IL-2 mRNP complex that responds to specific mRNA stabilizing signals. ..
  26. Nielsen P, Beahm D, Giepmans B, Baruch A, Hall J, Kumar N. Molecular cloning, functional expression, and tissue distribution of a novel human gap junction-forming protein, connexin-31.9. Interaction with zona occludens protein-1. J Biol Chem. 2002;277:38272-83 pubmed
    ..9 expression to vascular smooth muscle cells. Furthermore, it was demonstrated that Cx31.9 interacted with ZO-1. Thus, Cx31.9 represents a novel connexin gene that in vivo generates a protein with unique voltage gating properties. ..
  27. Shiu P, Metzenberg R. Meiotic silencing by unpaired DNA: properties, regulation and suppression. Genetics. 2002;161:1483-95 pubmed
    ..Meiotic silencing is confined to the ascus in which DNA is unpaired, and silencing does not spread to neighboring asci in a fruiting body of mixed genetic constitution. ..
  28. Saier M. The bacterial chromosome. Crit Rev Biochem Mol Biol. 2008;43:89-134 pubmed
    ..Some of the most throughly understood processes that underlie the dynamics of genomic structure and function in prokaryotes are examined. ..
  29. Hershberg R, Lipatov M, Small P, Sheffer H, Niemann S, Homolka S, et al. High functional diversity in Mycobacterium tuberculosis driven by genetic drift and human demography. PLoS Biol. 2008;6:e311 pubmed publisher
    ..tuberculosis described here, could contribute to the emergence and spread of drug-resistant tuberculosis. ..
  30. Das R, Karanicolas J, Baker D. Atomic accuracy in predicting and designing noncanonical RNA structure. Nat Methods. 2010;7:291-4 pubmed publisher
    ..Sequence redesign calculations recovered native bases at 65% of residues engaged in noncanonical interactions, and we experimentally validated mutations predicted to stabilize a signal recognition particle domain. ..
  31. Sheline C, Milocco L, Jones K. Two distinct nuclear transcription factors recognize loop and bulge residues of the HIV-1 TAR RNA hairpin. Genes Dev. 1991;5:2508-20 pubmed
    ..These findings suggest that the TAR element is recognized by two different nuclear RNA-binding proteins that affect transcriptional regulation by Tat. ..
  32. Rupp F, Payan D, Magill Solc C, Cowan D, Scheller R. Structure and expression of a rat agrin. Neuron. 1991;6:811-23 pubmed
    ..The agrin gene is expressed in rat embryonic nervous system and muscle. The rat agrin protein is concentrated at synapses, where it may play a role in development and regeneration. ..
  33. Hwang D, Kornberg A. A novel protein binds a key origin sequence to block replication of an E. coli minichromosome. Cell. 1990;63:325-31 pubmed
    ..The specificity of binding and profound inhibitory effect suggest a regulatory role for this protein at an early stage of chromosome initiation. ..
  34. Prince J, Milona N, Stallcup W. Characterization of a partial cDNA clone for the NILE glycoprotein and identification of the encoded polypeptide domain. J Neurosci. 1989;9:876-83 pubmed
    ..The cytoplasmic nature of the determinant is also indicated by its absence on a truncated, soluble form of NILE released from cells (possibly by a proteolytic mechanism) into the medium.(ABSTRACT TRUNCATED AT 250 WORDS) ..
  35. Masters B, Stohl L, Clayton D. Yeast mitochondrial RNA polymerase is homologous to those encoded by bacteriophages T3 and T7. Cell. 1987;51:89-99 pubmed
    ..Interestingly, the mitochondrial enzyme is highly homologous to the DNA-directed RNA polymerases of bacteriophages T3 and T7, especially in regions most highly conserved between the T3 and T7 enzymes themselves...
  36. Martin L, Crimaudo C, Gerace L. cDNA cloning and characterization of lamina-associated polypeptide 1C (LAP1C), an integral protein of the inner nuclear membrane. J Biol Chem. 1995;270:8822-8 pubmed
    ..Since the different LAP1 isotypes appear to bind lamins with different affinities, these changes in expression could be important for developmentally regulated alterations in nuclear structure. ..
  37. Berglund E, Ranscht B. Molecular cloning and in situ localization of the human contactin gene (CNTN1) on chromosome 12q11-q12. Genomics. 1994;21:571-82 pubmed
    ..The cloning of human contactin now permits the study of its role in disorders of the human nervous system. ..
  38. Goodrich L, Johnson R, Milenkovic L, McMahon J, Scott M. Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev. 1996;10:301-12 pubmed
    ..As in flies, mouse ptc transcription appears to be indicative of hedgehog signal reception. The results support the existence of a conserved signaling pathway used for pattern formation in insects and mammals. ..
  39. Liu F, Hsu D, Zuberi R, Hill P, Shenhav A, Kuwabara I, et al. Modulation of functional properties of galectin-3 by monoclonal antibodies binding to the non-lectin domains. Biochemistry. 1996;35:6073-9 pubmed
    ..The potentiating activities of some MAbs are probably due to facilitation of dimerization galectin-3, and the inhibitory activity of MAb B2C10 is probably the result of its disruption of the self-association process. ..
  40. Zhou J, Saba J. Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast. Biochem Biophys Res Commun. 1998;242:502-7 pubmed
    ..Chromosomal localization mapped this SPL gene to Chromosome 10 at 32 cM. Here, we report the identification of the first mammalian sphingosine phosphate lyase gene. ..
  41. Devlin P, Kay S. Cryptochromes are required for phytochrome signaling to the circadian clock but not for rhythmicity. Plant Cell. 2000;12:2499-2510 pubmed
    ..Importantly, Arabidopsis cry1 cry2 double mutants still show robust rhythmicity, indicating that cryptochromes do not form a part of the central circadian oscillator in plants as they do in mammals. ..
  42. Soares L, Seroogy C, Skrenta H, Anandasabapathy N, Lovelace P, Chung C, et al. Two isoforms of otubain 1 regulate T cell anergy via GRAIL. Nat Immunol. 2004;5:45-54 pubmed
    ..Thus, these two proteins have opposing epistatic functions in controlling the stability of GRAIL expression and the resultant anergy phenotype in T cells. ..
  43. Malloy P, Xu R, Cattani A, Reyes m, Feldman D. A unique insertion/substitution in helix H1 of the vitamin D receptor ligand binding domain in a patient with hereditary 1,25-dihydroxyvitamin D-resistant rickets. J Bone Miner Res. 2004;19:1018-24 pubmed
    ..This is the first time an insertion/substitution has been found as the defect-causing HVDRR. ..
  44. Dunn B, Sherlock G. Reconstruction of the genome origins and evolution of the hybrid lager yeast Saccharomyces pastorianus. Genome Res. 2008;18:1610-23 pubmed publisher
    ..cerevisiae ancestral parent for each of the independent S. pastorianus groups was an ale yeast, with different, but closely related ale strains contributing to each group's parentage. ..
  45. Won S, Eidenschenk C, Arnold C, Siggs O, Sun L, Brandl K, et al. Increased susceptibility to DNA virus infection in mice with a GCN2 mutation. J Virol. 2012;86:1802-8 pubmed publisher
    ..Importantly, homozygous Eif2ak4(atc) mice showed a modest increase in susceptibility to MCMV infection, demonstrating that translational arrest dependent on GCN2 contributes to the antiviral response in vivo. ..
  46. Tan J, Spudich J. Characterization and bacterial expression of the Dictyostelium myosin light chain kinase cDNA. Identification of an autoinhibitory domain. J Biol Chem. 1991;266:16044-9 pubmed
  47. Hasel K, Glass J, Godbout M, Sutcliffe J. An endoplasmic reticulum-specific cyclophilin. Mol Cell Biol. 1991;11:3484-91 pubmed
    ..These results suggest that cyclosporin A mediates its effect on cells through more than one cyclophilin and that cyclosporin A-induced misfolding of T-cell membrane proteins normally mediated by CPH2 plays a role in immunosuppression. ..
  48. Lew D, Dulic V, Reed S. Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast. Cell. 1991;66:1197-206 pubmed
    ..Cyclin C and E mRNAs accumulate periodically through the cell cycle, peaking at different times in G1. ..
  49. Chan E, Hamel J, Buyon J, Tan E. Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro autoantigen. J Clin Invest. 1991;87:68-76 pubmed
  50. Tekamp Olson P, Gallegos C, Bauer D, McClain J, Sherry B, Fabre M, et al. Cloning and characterization of cDNAs for murine macrophage inflammatory protein 2 and its human homologues. J Exp Med. 1990;172:911-9 pubmed
    ..These three human genes, MIP-2 alpha, MIP-2 beta, and gro/MGSA, constitute a sub-family within the cytokine family represented by platelet factor 4 and interleukin 8. ..
  51. Lasky L, Singer M, Yednock T, Dowbenko D, Fennie C, Rodriguez H, et al. Cloning of a lymphocyte homing receptor reveals a lectin domain. Cell. 1989;56:1045-55 pubmed
    ..This result supports a novel mechanism for the distribution of lymphocyte populations to various lymphoid organs. ..
  52. Prince J, Milona N, Stallcup W. Characterization of a partial cDNA clone for the NILE glycoprotein and identification of the encoded polypeptide domain. J Neurosci. 1989;9:1825-34 pubmed
    ..The clone contains an open reading frame coding for a 79 amino acid segment of the polypeptide that differs in only 2 residues from the cytoplasmic domain of the L1 glycoprotein. ..
  53. Crews S, Thomas J, Goodman C. The Drosophila single-minded gene encodes a nuclear protein with sequence similarity to the per gene product. Cell. 1988;52:143-51 pubmed
    ..No similarity is observed between sim and any known nuclear protein, but, surprisingly, it is similar to the Drosophila period (per) locus gene product, which controls the periodicity of biological rhythms. ..
  54. Truitt K, Hicks C, Imboden J. Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells. J Exp Med. 1994;179:1071-6 pubmed
    ..However, because CD28 is not known to be phosphorylated, it remains possible that CD28 interacts with PI3-K through a mechanism independent of tyrosine phosphorylation...
  55. Huang R, Darland T, Okamura D, Mercola D, Adamson E. Suppression of v-sis-dependent transformation by the transcription factor, Egr-1. Oncogene. 1994;9:1367-77 pubmed
    ..One function for Egr-1 implied by these results is the restraint of transformed growth in mitogen-stimulated cells. ..
  56. Schild H, Mavaddat N, Litzenberger C, Ehrich E, Davis M, Bluestone J, et al. The nature of major histocompatibility complex recognition by gamma delta T cells. Cell. 1994;76:29-37 pubmed
    ..These results suggest that the molecular nature of gamma delta T cell recognition is fundamentally different than that of alpha beta T cells. ..
  57. Ortiz M, Piedrafita F, Pfahl M, Maki R. TOR: a new orphan receptor expressed in the thymus that can modulate retinoid and thyroid hormone signals. Mol Endocrinol. 1995;9:1679-91 pubmed
    ..However, the response elements recognized by TOR and COUP-TF differ as do the expression patterns of these receptors. Thus, one important role of TOR could be to modulate retinoid and thyroid hormone signals in the thymus. ..
  58. Johnson R, Rothman A, Xie J, Goodrich L, Bare J, Bonifas J, et al. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science. 1996;272:1668-71 pubmed
    ..The human PTC gene appears to be crucial for proper embryonic development and for tumor suppression...
  59. Diaz E, Schimmöller F, Pfeffer S. A novel Rab9 effector required for endosome-to-TGN transport. J Cell Biol. 1997;138:283-90 pubmed
    ..These data are consistent with a model in which p40 and Rab9 act together to drive the process of transport vesicle docking. ..
  60. Feng Y, Huang H, Liao J, Cohen S. Escherichia coli poly(A)-binding proteins that interact with components of degradosomes or impede RNA decay mediated by polynucleotide phosphorylase and RNase E. J Biol Chem. 2001;276:31651-6 pubmed
    ..Our findings raise the prospect that E. coli proteins that bind to poly(A) tails may link the functions of degradosomes and ribosomes. ..
  61. Gunn T, Inui T, Kitada K, Ito S, Wakamatsu K, He L, et al. Molecular and phenotypic analysis of Attractin mutant mice. Genetics. 2001;158:1683-95 pubmed
  62. Brudno M, Do C, Cooper G, Kim M, Davydov E, Green E, et al. LAGAN and Multi-LAGAN: efficient tools for large-scale multiple alignment of genomic DNA. Genome Res. 2003;13:721-31 pubmed
    ..Multi-LAGAN is a practical method for generating multiple alignments of long genomic sequences at any evolutionary distance. Our systems are publicly available at
  63. Kim H, Lapointe J, Kaygusuz G, Ong D, Li C, van de Rijn M, et al. The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer. Cancer Res. 2005;65:8118-24 pubmed
    ..Taken together, our findings implicate ALDH1a2 as a candidate tumor suppressor gene in prostate cancer and further support a role of retinoids in the prevention or treatment of prostate cancer. ..
  64. Miskinyte S, Butler M, Herve D, Sarret C, Nicolino M, Petralia J, et al. Loss of BRCC3 deubiquitinating enzyme leads to abnormal angiogenesis and is associated with syndromic moyamoya. Am J Hum Genet. 2011;88:718-728 pubmed publisher
  65. DiTacchio L, Bowles J, Shin S, Lim D, Koopman P, Janknecht R. Transcription factors ER71/ETV2 and SOX9 participate in a positive feedback loop in fetal and adult mouse testis. J Biol Chem. 2012;287:23657-66 pubmed publisher
    ..Thereby, ER71 and SOX9 may affect late testis development as well as the function of the adult male gonad. ..
  66. Su L, Hershberger R, Weissman I. LYAR, a novel nucleolar protein with zinc finger DNA-binding motifs, is involved in cell growth regulation. Genes Dev. 1993;7:735-48 pubmed
    ..Therefore, LYAR may function as a novel nucleolar oncoprotein to regulate cell growth. ..
  67. McDowall K, Lin Chao S, Cohen S. A+U content rather than a particular nucleotide order determines the specificity of RNase E cleavage. J Biol Chem. 1994;269:10790-6 pubmed
  68. Luznik L, Martone M, Kraus G, Zhang Y, Xu Y, Ellisman M, et al. Localization of human immunodeficiency virus Rev in transfected and virus-infected cells. AIDS Res Hum Retroviruses. 1995;11:795-804 pubmed
    ..Our observations are consistent with the proposed dual role of Rev in mRNA transport and splicing. ..
  69. Kain R, Angata K, Kerjaschki D, Fukuda M. Molecular cloning and expression of a novel human trans-Golgi network glycoprotein, TGN51, that contains multiple tyrosine-containing motifs. J Biol Chem. 1998;273:981-8 pubmed
    ..In contrast, mutated hTGN48 and hTGN46 are no longer retrieved to the TGN. These results strongly suggest that hTGN51 may have a unique function compared with hTGN46 or hTGN48 in shuttling between the cell surface and the TGN. ..
  70. Maldonado A, Doerner P, Dixon R, Lamb C, Cameron R. A putative lipid transfer protein involved in systemic resistance signalling in Arabidopsis. Nature. 2002;419:399-403 pubmed
    ..DIR1 encodes a putative apoplastic lipid transfer protein and we propose that DIR1 interacts with a lipid-derived molecule to promote long distance signalling. ..
  71. Bitto E, McKay D. The periplasmic molecular chaperone protein SurA binds a peptide motif that is characteristic of integral outer membrane proteins. J Biol Chem. 2003;278:49316-22 pubmed
    ..Thus, SurA recognizes a peptide motif that is characteristic of integral outer membrane proteins. ..
  72. Bethune M, Khosla C. Parallels between pathogens and gluten peptides in celiac sprue. PLoS Pathog. 2008;4:e34 pubmed publisher
  73. Danesch U, Hoeck W, Ringold G. Cloning and transcriptional regulation of a novel adipocyte-specific gene, FSP27. CAAT-enhancer-binding protein (C/EBP) and C/EBP-like proteins interact with sequences required for differentiation-dependent expression. J Biol Chem. 1992;267:7185-93 pubmed
    ..We suggest that C/EBP and other C/EBP-like proteins play a critical role in regulating the transcription of the fat-specific gene FSP27. ..
  74. Yamaguchi M, Hatefi Y, Trach K, Hoch J. The primary structure of the mitochondrial energy-linked nicotinamide nucleotide transhydrogenase deduced from the sequence of cDNA clones. J Biol Chem. 1988;263:2761-7 pubmed
    ..M., Loo, T.W., Gillam, S., and Bragg, P.D. (1986) Eur. J. Biochem. 158, 647-653). ..
  75. Shiozaki K, Akhavan Niaki H, McGowan C, Russell P. Protein phosphatase 2C, encoded by ptc1+, is important in the heat shock response of Schizosaccharomyces pombe. Mol Cell Biol. 1994;14:3742-51 pubmed
    ..Moreover, ptc1+ mRNA levels increase 5- to 10-fold during heat shock. These data, demonstrating that Ptc1 activity is important for survival of heat shock, provide one of the first genetic clues as to the biological functions of PP2C. ..
  76. Li L, Cohen S. Tsg101: a novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells. Cell. 1996;85:319-29 pubmed
    ..Overexpression of tsg101 antisense transcripts in naive 3T3 cells resulted in cell transformation and increased stathmin-specific mRNA. ..
  77. Yaoi T, Laksanalamai P, Jiemjit A, Kagawa H, Alton T, Trent J. Cloning and characterization of ftsZ and pyrF from the archaeon Thermoplasma acidophilum. Biochem Biophys Res Commun. 2000;275:936-45 pubmed
    ..Sequence alignments of ODCs from archaea, bacteria, and eukarya reveal five conserved regions, two of which have homology to 3-hexulose-6-phosphate synthase (HPS), suggesting a common substrate recognition and binding motif. ..
  78. Yeo G, Van Nostrand E, Nostrand E, Liang T. Discovery and analysis of evolutionarily conserved intronic splicing regulatory elements. PLoS Genet. 2007;3:e85 pubmed
    ..Our results demonstrate that ISREs are crucial building blocks in understanding general and tissue-specific AS regulation and the biological pathways and functions regulated by these AS events. ..
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