Experts and Doctors on zebrafish proteins in Nottingham, England, United Kingdom
Locale: Nottingham, England, United Kingdom
Topic: zebrafish proteins
Yi C, Terrett J, Li Q, Ellington K, Packham E, Armstrong Buisseret L, et al
. Identification, mapping, and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19. Genomics. 1999;55:10-20 pubmed
..TBX19 is an orthologue of chick TbxT and maps at 1q23-q24. The genomic organization of TBX19 is highly similar to that of human T(Brachyury), another human member of the same subfamily. ..
Dee C, Gibson A, Rengifo A, Sun S, Patient R, Scotting P. A change in response to Bmp signalling precedes ectodermal fate choice. Int J Dev Biol. 2007;51:79-84 pubmed
..Hence, we have shown a dynamic change in the molecular machinery underlying the Bmp response in the ectoderm during gastrulation stages of development. ..
Sun S, Dee C, Tripathi V, Rengifo A, Hirst C, Scotting P. Epibranchial and otic placodes are induced by a common Fgf signal, but their subsequent development is independent. Dev Biol. 2007;303:675-86 pubmed
Rowlinson J, Gering M. Hey2 acts upstream of Notch in hematopoietic stem cell specification in zebrafish embryos. Blood. 2010;116:2046-56 pubmed publisher
..These results establish an essential role for Hey2 upstream of Notch in HSC formation. ..
Shih Y, Kuo C, Hirst C, Dee C, Liu Y, Laghari Z, et al
. SoxB1 transcription factors restrict organizer gene expression by repressing multiple events downstream of Wnt signalling. Development. 2010;137:2671-81 pubmed publisher
..It therefore seems that the broad expression of these SoxB1 genes throughout the early epiblast and their subsequent restriction to the ectoderm is a primary regulator of when and where the organizer forms. ..
Machuca Tzili L, Buxton S, Thorpe A, Timson C, Wigmore P, Luther P, et al
. Zebrafish deficient for Muscleblind-like 2 exhibit features of myotonic dystrophy. Dis Model Mech. 2011;4:381-92 pubmed publisher
Goudevenou K, Martin P, Yeh Y, Jones P, Sablitzky F. Def6 is required for convergent extension movements during zebrafish gastrulation downstream of Wnt5b signaling. PLoS ONE. 2011;6:e26548 pubmed publisher
..In addition, by knocking down both def6 and Wnt11, we show that def6 synergises with the Wnt11 signaling pathway. ..
Ketley A, Warren A, Holmes E, Gering M, Aboobaker A, Brook J. The miR-30 microRNA family targets smoothened to regulate hedgehog signalling in zebrafish early muscle development. PLoS ONE. 2013;8:e65170 pubmed publisher
..Our results indicate that fine coordination of smoothened activity by the miR-30 family allows the correct specification and differentiation of distinct muscle cell types during zebrafish embryonic development. ..