Experts and Doctors on x chromosome in Cambridge, England, United Kingdom
Locale: Cambridge, England, United Kingdom
Topic: x chromosome
Derry J, Barnard P. Physical linkage of the A-raf-1, properdin, synapsin I, and TIMP genes on the human and mouse X chromosomes. Genomics. 1992;12:632-8 pubmed
..Analysis of the corresponding region of the human X chromosome indicates a similar arrangement and in addition shows that the properdin gene lies within 5 kb of the 5' end of the synapsin I gene. ..
Derry J, Barnard P. Mapping of the glycine receptor alpha 2-subunit gene and the GABAA alpha 3-subunit gene on the mouse X chromosome. Genomics. 1991;10:593-7 pubmed
..This establishes the XF region of the mouse X chromosome as homologous with the Xp22.1-p22.3 region of the human X chromosome and indicates the presence of an evolutionary breakpoint in the region of Xp21.3. ..
Barnard P, Derry J, Ryder Cook A, Zander N, Kilimann M. Mapping of the phosphorylase kinase alpha subunit gene on the mouse X chromosome. Cytogenet Cell Genet. 1990;53:91-4 pubmed
Geng Y, Derry J, Hendrickx J, Coucke P, Willems P, Barnard P. Mapping of a liver phosphorylase kinase alpha-subunit gene on the mouse X chromosome. Genomics. 1993;15:191-3 pubmed
..This mapping position would suggest a location for the human liver alpha-subunit gene on the proximal short arm of the X chromosome, a region recently implicated in X-linked liver glycogenosis (XLG). ..
Blanco P, Sargent C, Boucher C, Howell G, Ross M, Affara N. A novel poly(A)-binding protein gene (PABPC5) maps to an X-specific subinterval in the Xq21.3/Yp11.2 homology block of the human sex chromosomes. Genomics. 2001;74:1-11 pubmed publisher
..The close proximity of this gene to translocation breakpoints associated with premature ovarian failure makes it a potential candidate for this condition...
Valor L, Grant S. Clustered gene expression changes flank targeted gene loci in knockout mice. PLoS ONE. 2007;2:e1303 pubmed
..The apparent clustering of these genes was explained by the presence of flanking DNA from the parental ES cell. We provide recommendations for the analysis and reporting of microarray data from knockout mice. ..
Vaquerizas J, Suyama R, Kind J, Miura K, Luscombe N, Akhtar A. Nuclear pore proteins nup153 and megator define transcriptionally active regions in the Drosophila genome. PLoS Genet. 2010;6:e1000846 pubmed publisher
..Therefore, we suggest that NAR-binding is used for chromosomal organization that enables gene expression control. ..
Laing R, Hunt M, Protasio A, Saunders G, Mungall K, Laing S, et al
. Annotation of two large contiguous regions from the Haemonchus contortus genome using RNA-seq and comparative analysis with Caenorhabditis elegans. PLoS ONE. 2011;6:e23216 pubmed publisher
..contortus. Our findings suggest that a combination of RNA-seq and comparative analysis with C. elegans is a powerful approach for the annotation and analysis of strongylid nematode genomes. ..
Vielle A, Lang J, Dong Y, Ercan S, Kotwaliwale C, Rechtsteiner A, et al
. H4K20me1 contributes to downregulation of X-linked genes for C. elegans dosage compensation. PLoS Genet. 2012;8:e1002933 pubmed publisher
..H4K20me1 is important for mitotic chromosome condensation in mammals, suggesting that increased H4K20me1 on the X may restrict access of the transcription machinery to X-linked genes via chromatin compaction. ..