Experts and Doctors on insecticides in Liverpool, England, United Kingdom
Locale: Liverpool, England, United Kingdom
Coleman M, Sharp B, Seocharan I, Hemingway J. Developing an evidence-based decision support system for rational insecticide choice in the control of African malaria vectors. J Med Entomol. 2006;43:663-8 pubmed
M ller P, Warr E, Stevenson B, Pignatelli P, Morgan J, Steven A, et al
. Field-caught permethrin-resistant Anopheles gambiae overexpress CYP6P3, a P450 that metabolises pyrethroids. PLoS Genet. 2008;4:e1000286 pubmed publisher
..This is the first study to demonstrate the capacity of a P450 identified in wild A. gambiae to metabolise insecticides. The findings add to the understanding of the genetic basis of insecticide resistance in wild mosquito populations...
Morgan J, Irving H, Okedi L, Steven A, Wondji C. Pyrethroid resistance in an Anopheles funestus population from Uganda. PLoS ONE. 2010;5:e11872 pubmed publisher
..funestus may be more widespread than previously assumed and therefore this should be taken into account for the implementation and management of vector control programs in Africa. ..
Stevenson B, Pignatelli P, Nikou D, Paine M. Pinpointing P450s associated with pyrethroid metabolism in the dengue vector, Aedes aegypti: developing new tools to combat insecticide resistance. PLoS Negl Trop Dis. 2012;6:e1595 pubmed publisher
..P450s have been identified with the potential to confer pyrethroid resistance in Ae.aegypti. It is recommended that over expression of these enzymes should be monitored as indicators of resistance where pyrethroids are used. ..
Strode C, de Melo Santos M, Magalhaes T, Araújo A, Ayres C. Expression profile of genes during resistance reversal in a temephos selected strain of the dengue vector, Aedes aegypti. PLoS ONE. 2012;7:e39439 pubmed publisher
..aegypti. The identification of gene expression signatures associated to insecticide resistance and their suppression could greatly aid the development of improved strategies of vector control. ..
Jones C, Toé H, Sanou A, Namountougou M, Hughes A, Diabate A, et al
. Additional selection for insecticide resistance in urban malaria vectors: DDT resistance in Anopheles arabiensis from Bobo-Dioulasso, Burkina Faso. PLoS ONE. 2012;7:e45995 pubmed publisher
Barnes K, Weedall G, Ndula M, Irving H, Mzihalowa T, Hemingway J, et al
. Genomic Footprints of Selective Sweeps from Metabolic Resistance to Pyrethroids in African Malaria Vectors Are Driven by Scale up of Insecticide-Based Vector Control. PLoS Genet. 2017;13:e1006539 pubmed publisher
..If this level of selection and spread of resistance continues unabated, our ability to control malaria with current interventions will be compromised. ..
Silva Martins W, Wilding C, Steen K, Mawejje H, Antão T, DONNELLY M. Local selection in the presence of high levels of gene flow: Evidence of heterogeneous insecticide selection pressure across Ugandan Culex quinquefasciatus populations. PLoS Negl Trop Dis. 2017;11:e0005917 pubmed publisher