Experts and Doctors on complement c4 in Leicester, England, United Kingdom

Summary

Locale: Leicester, England, United Kingdom
Topic: complement c4

Top Publications

  1. Ali Y, Lynch N, Haleem K, Fujita T, Endo Y, Hansen S, et al. The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection. PLoS Pathog. 2012;8:e1002793 pubmed publisher
    ..This study corroborates the essential function of MASP-2 in the lectin pathway and highlights the importance of MBL-independent lectin pathway activation in the host defense against pneumococci. ..
  2. Asgari E, Farrar C, Lynch N, Ali Y, Roscher S, Stover C, et al. Mannan-binding lectin-associated serine protease 2 is critical for the development of renal ischemia reperfusion injury and mediates tissue injury in the absence of complement C4. FASEB J. 2014;28:3996-4003 pubmed publisher
    ..Our study highlights the role of LP activation in renal IR injury and indicates that injury occurs through MASP-2-dependent activation events independent of C4. ..