Experts and Doctors on apolipoproteins e in Leeds, England, United Kingdom
Locale: Leeds, England, United Kingdom
Topic: apolipoproteins e
Rajwani A, Ezzat V, Smith J, Yuldasheva N, Duncan E, Gage M, et al
. Increasing circulating IGFBP1 levels improves insulin sensitivity, promotes nitric oxide production, lowers blood pressure, and protects against atherosclerosis. Diabetes. 2012;61:915-24 pubmed publisher
Bunce D, Bielak A, Anstey K, Cherbuin N, Batterham P, Easteal S. APOE genotype and cognitive change in young, middle-aged, and older adults living in the community. J Gerontol A Biol Sci Med Sci. 2014;69:379-86 pubmed publisher
..The findings suggest that in the absence of clinically salient dementia pathology, APOE ?2 and ?4 alleles do not exhibit antagonistic pleiotropy in relation to cognition between the ages of 20 and 72 years. ..
Bridge K, Revill C, Macrae F, Bailey M, Yuldasheva N, Wheatcroft S, et al
. Inhibition of plasmin-mediated TAFI activation may affect development but not progression of abdominal aortic aneurysms. PLoS ONE. 2017;12:e0177117 pubmed publisher
..Late treatment with a TAFI inhibitor does not prevent AAA progression. These data may indicate a role for inhibition of plasmin-mediated TAFI activation in the early stages of AAA development, but not in its progression. ..
Christiansen M, Larsen S, Nyegaard M, Neergaard Petersen S, Ajjan R, Würtz M, et al
. Coronary artery disease-associated genetic variants and biomarkers of inflammation. PLoS ONE. 2017;12:e0180365 pubmed publisher
..No other genetic variants or the combined effect of all variants were associated with the five inflammatory biomarkers. ..