Experts and Doctors on rna precursors in Boulder, Colorado, United States

Summary

Locale: Boulder, Colorado, United States
Topic: rna precursors

Top Publications

  1. Ishikawa F, Matunis M, Dreyfuss G, Cech T. Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n. Mol Cell Biol. 1993;13:4301-10 pubmed
    ..These studies establish the binding specificities of these D and E hnRNPs. Furthermore, they suggest the possibility that these hnRNPs could perhaps bind to chromosome telomeres, in addition to having a role in pre-mRNA metabolism. ..
  2. Tanner M, Cech T. Activity and thermostability of the small self-splicing group I intron in the pre-tRNA(lle) of the purple bacterium Azoarcus. RNA. 1996;2:74-83 pubmed
    ..Thus, even superficially similar group I introns from the same structural subgroup can differ significantly in activity and stability. ..
  3. Tanner M, Anderson E, Gutell R, Cech T. Mutagenesis and comparative sequence analysis of a base triple joining the two domains of group I ribozymes. RNA. 1997;3:1037-51 pubmed
    ..Repositioning of the base triple to form a new set of interactions may be required for the second step of splicing. ..
  4. Cui M, Allen M, Larsen A, MacMorris M, Han M, Blumenthal T. Genes involved in pre-mRNA 3'-end formation and transcription termination revealed by a lin-15 operon Muv suppressor screen. Proc Natl Acad Sci U S A. 2008;105:16665-70 pubmed publisher
    ..Furthermore, our results implicate a serine/arginine-rich (SR) protein, SRp20, in events following 3'-end cleavage, leading to termination of transcription. ..

Detail Information

Publications4

  1. Ishikawa F, Matunis M, Dreyfuss G, Cech T. Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n. Mol Cell Biol. 1993;13:4301-10 pubmed
    ..These studies establish the binding specificities of these D and E hnRNPs. Furthermore, they suggest the possibility that these hnRNPs could perhaps bind to chromosome telomeres, in addition to having a role in pre-mRNA metabolism. ..
  2. Tanner M, Cech T. Activity and thermostability of the small self-splicing group I intron in the pre-tRNA(lle) of the purple bacterium Azoarcus. RNA. 1996;2:74-83 pubmed
    ..Thus, even superficially similar group I introns from the same structural subgroup can differ significantly in activity and stability. ..
  3. Tanner M, Anderson E, Gutell R, Cech T. Mutagenesis and comparative sequence analysis of a base triple joining the two domains of group I ribozymes. RNA. 1997;3:1037-51 pubmed
    ..Repositioning of the base triple to form a new set of interactions may be required for the second step of splicing. ..
  4. Cui M, Allen M, Larsen A, MacMorris M, Han M, Blumenthal T. Genes involved in pre-mRNA 3'-end formation and transcription termination revealed by a lin-15 operon Muv suppressor screen. Proc Natl Acad Sci U S A. 2008;105:16665-70 pubmed publisher
    ..Furthermore, our results implicate a serine/arginine-rich (SR) protein, SRp20, in events following 3'-end cleavage, leading to termination of transcription. ..