Experts and Doctors on epsilonretrovirus in Fort Collins, Colorado, United States

Summary

Locale: Fort Collins, Colorado, United States
Topic: epsilonretrovirus

Top Publications

  1. Daniels C, Rovnak J, Quackenbush S. Walleye dermal sarcoma virus Orf B functions through receptor for activated C kinase (RACK1) and protein kinase C. Virology. 2008;375:550-60 pubmed publisher
    ..Orf B associates with PKCalpha, which is constitutively activated and localized at the membrane. Activated PKC promoted cell survival, proliferation, and increased cell viability in Orf B-expressing cells...
  2. Brewster C, Birkenheuer C, Vogt M, Quackenbush S, Rovnak J. The retroviral cyclin of walleye dermal sarcoma virus binds cyclin-dependent kinases 3 and 8. Virology. 2011;409:299-307 pubmed publisher
    ..Co-IP and pulldowns demonstrate direct rv-cyclin binding to cdk3 as well. The rv-cyclin functions as a structural ortholog of cyclin C in spite of its limited amino acid sequence identity with C cyclins or with any known cyclins...
  3. Rovnak J, Brewster C, Quackenbush S. Retroviral cyclin enhances cyclin-dependent kinase-8 activity. J Virol. 2012;86:5742-51 pubmed publisher
  4. Rovnak J, Quackenbush S. Walleye dermal sarcoma virus retroviral cyclin directly contacts TAF9. J Virol. 2006;80:12041-8 pubmed publisher
    ..A similar motif is present in the rv-cyclin AD, and point mutations within this motif affect rv-cyclin function and protein-protein interactions. The results support a model of transcription regulation by direct interaction with TAF9...
  5. Quackenbush S, Linton A, Brewster C, Rovnak J. Walleye dermal sarcoma virus rv-cyclin inhibits NF-kappaB-dependent transcription. Virology. 2009;386:55-60 pubmed publisher
    ..Furthermore, interference with NF-kappaB is dependent upon an intact TAF9-binding motif in rv-cyclin. The outcome of this NF-kappaB down regulation is likely to be important in the control of virus replication and tumorigenesis...

Detail Information

Publications5

  1. Daniels C, Rovnak J, Quackenbush S. Walleye dermal sarcoma virus Orf B functions through receptor for activated C kinase (RACK1) and protein kinase C. Virology. 2008;375:550-60 pubmed publisher
    ..Orf B associates with PKCalpha, which is constitutively activated and localized at the membrane. Activated PKC promoted cell survival, proliferation, and increased cell viability in Orf B-expressing cells...
  2. Brewster C, Birkenheuer C, Vogt M, Quackenbush S, Rovnak J. The retroviral cyclin of walleye dermal sarcoma virus binds cyclin-dependent kinases 3 and 8. Virology. 2011;409:299-307 pubmed publisher
    ..Co-IP and pulldowns demonstrate direct rv-cyclin binding to cdk3 as well. The rv-cyclin functions as a structural ortholog of cyclin C in spite of its limited amino acid sequence identity with C cyclins or with any known cyclins...
  3. Rovnak J, Brewster C, Quackenbush S. Retroviral cyclin enhances cyclin-dependent kinase-8 activity. J Virol. 2012;86:5742-51 pubmed publisher
  4. Rovnak J, Quackenbush S. Walleye dermal sarcoma virus retroviral cyclin directly contacts TAF9. J Virol. 2006;80:12041-8 pubmed publisher
    ..A similar motif is present in the rv-cyclin AD, and point mutations within this motif affect rv-cyclin function and protein-protein interactions. The results support a model of transcription regulation by direct interaction with TAF9...
  5. Quackenbush S, Linton A, Brewster C, Rovnak J. Walleye dermal sarcoma virus rv-cyclin inhibits NF-kappaB-dependent transcription. Virology. 2009;386:55-60 pubmed publisher
    ..Furthermore, interference with NF-kappaB is dependent upon an intact TAF9-binding motif in rv-cyclin. The outcome of this NF-kappaB down regulation is likely to be important in the control of virus replication and tumorigenesis...