Genomes and Genes
Experts and Doctors on gene regulatory networks in Davis, California, United States
Locale: Davis, California, United States
Topic: gene regulatory networks
- Gompers A, Su Feher L, Ellegood J, Copping N, Riyadh M, Stradleigh T, et al. Germline Chd8 haploinsufficiency alters brain development in mouse. Nat Neurosci. 2017;20:1062-1073 pubmed publisher..This integrative analysis offers an initial picture of the consequences of Chd8 haploinsufficiency for brain development. ..
- Krishnamoorthy V, Kannanganat S, Maienschein Cline M, Cook S, Chen J, Bahroos N, et al. The IRF4 Gene Regulatory Module Functions as a Read-Write Integrator to Dynamically Coordinate TÂ Helper Cell Fate. Immunity. 2017;47:481-497.e7 pubmed publisher..We propose that the Irf4 locus functions as the "reader" of TCR signal strength, and in turn, concentration-dependent activity of Irf4 "writes" T helper fate choice. ..