Experts and Doctors on gamma rays in Davis, California, United States

Summary

Locale: Davis, California, United States
Topic: gamma rays

Top Publications

  1. Jiang C, Yen C, Cronin K, Mitchell D, Britt A. UV- and gamma-radiation sensitive mutants of Arabidopsis thaliana. Genetics. 1997;147:1401-9 pubmed
  2. Meeusen S, Tieu Q, Wong E, Weiss E, Schieltz D, Yates J, et al. Mgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNA. J Cell Biol. 1999;145:291-304 pubmed
    ..Thus, we propose that Mgm101p performs an essential function in the repair of oxidatively damaged mtDNA that is required for the maintenance of the mitochondrial genome. ..
  3. Hefner E, Huefner N, Britt A. Tissue-specific regulation of cell-cycle responses to DNA damage in Arabidopsis seedlings. DNA Repair (Amst). 2006;5:102-10 pubmed
    ..We find that the ionizing radiation (IR)-induced cell-cycle responses observed in the root and shoot tip meristems do not apply to more differentiated tissues. ..
  4. Yoshiyama K, Conklin P, Huefner N, Britt A. Suppressor of gamma response 1 (SOG1) encodes a putative transcription factor governing multiple responses to DNA damage. Proc Natl Acad Sci U S A. 2009;106:12843-8 pubmed publisher
    ..We propose that, in plants, signals related to genomic stress are processed through a single, central transcription factor, SOG1. ..
  5. Cho S, Rossi A, Jung Y, Yan W, Liu G, Zhang J, et al. Ninjurin1, a target of p53, regulates p53 expression and p53-dependent cell survival, senescence, and radiation-induced mortality. Proc Natl Acad Sci U S A. 2013;110:9362-7 pubmed publisher
    ..Thus, we postulate that as a membrane adhesion molecule, Ninj1 is an ideal target to regulate p53 activity via the p53-Ninj1 loop. ..
  6. Rasooly R, Zhang P, Tibolla A, Hawley R. A structure-function analysis of NOD, a kinesin-like protein from Drosophila melanogaster. Mol Gen Genet. 1994;242:145-51 pubmed
    ..These findings are consistent with the biochemical basis of the mode of action of each mutagen. ..
  7. Hefner E, Preuss S, Britt A. Arabidopsis mutants sensitive to gamma radiation include the homologue of the human repair gene ERCC1. J Exp Bot. 2003;54:669-80 pubmed
    ..The gamma-plantlet screen used here also reveals two general mutant classes based on size of cotyledons and hypocotyls. One of the mutants discovered is a homologue of the mammalian nucleotide excision repair gene ERCC1. ..
  8. Preuss S, Britt A. A DNA-damage-induced cell cycle checkpoint in Arabidopsis. Genetics. 2003;164:323-34 pubmed

Detail Information

Publications8

  1. Jiang C, Yen C, Cronin K, Mitchell D, Britt A. UV- and gamma-radiation sensitive mutants of Arabidopsis thaliana. Genetics. 1997;147:1401-9 pubmed
  2. Meeusen S, Tieu Q, Wong E, Weiss E, Schieltz D, Yates J, et al. Mgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNA. J Cell Biol. 1999;145:291-304 pubmed
    ..Thus, we propose that Mgm101p performs an essential function in the repair of oxidatively damaged mtDNA that is required for the maintenance of the mitochondrial genome. ..
  3. Hefner E, Huefner N, Britt A. Tissue-specific regulation of cell-cycle responses to DNA damage in Arabidopsis seedlings. DNA Repair (Amst). 2006;5:102-10 pubmed
    ..We find that the ionizing radiation (IR)-induced cell-cycle responses observed in the root and shoot tip meristems do not apply to more differentiated tissues. ..
  4. Yoshiyama K, Conklin P, Huefner N, Britt A. Suppressor of gamma response 1 (SOG1) encodes a putative transcription factor governing multiple responses to DNA damage. Proc Natl Acad Sci U S A. 2009;106:12843-8 pubmed publisher
    ..We propose that, in plants, signals related to genomic stress are processed through a single, central transcription factor, SOG1. ..
  5. Cho S, Rossi A, Jung Y, Yan W, Liu G, Zhang J, et al. Ninjurin1, a target of p53, regulates p53 expression and p53-dependent cell survival, senescence, and radiation-induced mortality. Proc Natl Acad Sci U S A. 2013;110:9362-7 pubmed publisher
    ..Thus, we postulate that as a membrane adhesion molecule, Ninj1 is an ideal target to regulate p53 activity via the p53-Ninj1 loop. ..
  6. Rasooly R, Zhang P, Tibolla A, Hawley R. A structure-function analysis of NOD, a kinesin-like protein from Drosophila melanogaster. Mol Gen Genet. 1994;242:145-51 pubmed
    ..These findings are consistent with the biochemical basis of the mode of action of each mutagen. ..
  7. Hefner E, Preuss S, Britt A. Arabidopsis mutants sensitive to gamma radiation include the homologue of the human repair gene ERCC1. J Exp Bot. 2003;54:669-80 pubmed
    ..The gamma-plantlet screen used here also reveals two general mutant classes based on size of cotyledons and hypocotyls. One of the mutants discovered is a homologue of the mammalian nucleotide excision repair gene ERCC1. ..
  8. Preuss S, Britt A. A DNA-damage-induced cell cycle checkpoint in Arabidopsis. Genetics. 2003;164:323-34 pubmed