Experts and Doctors on dominant genes in Davis, California, United States

Summary

Locale: Davis, California, United States
Topic: dominant genes

Top Publications

  1. Matthies H, Messina L, Namba R, Greer K, Walker M, Hawley R. Mutations in the alpha-tubulin 67C gene specifically impair achiasmate segregation in Drosophila melanogaster. J Cell Biol. 1999;147:1137-44 pubmed
    ..These results suggest that the accurate segregation of achiasmate chromosomes requires the proper balancing of forces acting on the chromosomes during prometaphase. ..
  2. Page S, McKim K, Deneen B, Van Hook T, Hawley R. Genetic studies of mei-P26 reveal a link between the processes that control germ cell proliferation in both sexes and those that control meiotic exchange in Drosophila. Genetics. 2000;155:1757-72 pubmed
    ..These data suggest that the pathways controlling germline differentiation and meiotic exchange are related and that factors involved in the mitotic divisions of the germline may regulate meiotic recombination. ..
  3. Kiger J, Natzle J, Green M. Hemocytes are essential for wing maturation in Drosophila melanogaster. Proc Natl Acad Sci U S A. 2001;98:10190-5 pubmed
    ..We propose that batone is required for the release of a hormone necessary for wing expansion and tissue remodeling by hemocytes in the wing. ..
  4. Lee J, Zhao L, Youn H, Weatherill A, Tapping R, Feng L, et al. Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1. J Biol Chem. 2004;279:16971-9 pubmed
    ..These results also suggest that inflammatory responses induced by the activation of TLRs can be differentially modulated by types of dietary fatty acids. ..
  5. Goodson M, Jonas B, Privalsky M. Alternative mRNA splicing of SMRT creates functional diversity by generating corepressor isoforms with different affinities for different nuclear receptors. J Biol Chem. 2005;280:7493-503 pubmed
    ..Our results suggest that differential mRNA splicing serves to customize corepressor function in different cells, allowing the transcriptional properties of nuclear receptors to be adapted to different contexts. ..
  6. Zhang Z, Ober J, Kliebenstein D. The gene controlling the quantitative trait locus EPITHIOSPECIFIER MODIFIER1 alters glucosinolate hydrolysis and insect resistance in Arabidopsis. Plant Cell. 2006;18:1524-36 pubmed
    ..The glucosinolate hydrolysis profile change influenced by ESM1 is associated with the ability to deter herbivory by Trichoplusia ni. This gene could provide unique approaches toward improving human nutrition. ..
  7. Su Y, Lagarias J. Light-independent phytochrome signaling mediated by dominant GAF domain tyrosine mutants of Arabidopsis phytochromes in transgenic plants. Plant Cell. 2007;19:2124-39 pubmed
    ..We conclude that the universally conserved GAF domain Tyr residue, with which the bilin chromophore is intimately associated, performs a critical role in coupling light perception to signal transduction by plant phytochromes. ..
  8. Rosen M, Privalsky M. Thyroid hormone receptor mutations found in renal clear cell carcinomas alter corepressor release and reveal helix 12 as key determinant of corepressor specificity. Mol Endocrinol. 2009;23:1183-92 pubmed publisher

Detail Information

Publications8

  1. Matthies H, Messina L, Namba R, Greer K, Walker M, Hawley R. Mutations in the alpha-tubulin 67C gene specifically impair achiasmate segregation in Drosophila melanogaster. J Cell Biol. 1999;147:1137-44 pubmed
    ..These results suggest that the accurate segregation of achiasmate chromosomes requires the proper balancing of forces acting on the chromosomes during prometaphase. ..
  2. Page S, McKim K, Deneen B, Van Hook T, Hawley R. Genetic studies of mei-P26 reveal a link between the processes that control germ cell proliferation in both sexes and those that control meiotic exchange in Drosophila. Genetics. 2000;155:1757-72 pubmed
    ..These data suggest that the pathways controlling germline differentiation and meiotic exchange are related and that factors involved in the mitotic divisions of the germline may regulate meiotic recombination. ..
  3. Kiger J, Natzle J, Green M. Hemocytes are essential for wing maturation in Drosophila melanogaster. Proc Natl Acad Sci U S A. 2001;98:10190-5 pubmed
    ..We propose that batone is required for the release of a hormone necessary for wing expansion and tissue remodeling by hemocytes in the wing. ..
  4. Lee J, Zhao L, Youn H, Weatherill A, Tapping R, Feng L, et al. Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1. J Biol Chem. 2004;279:16971-9 pubmed
    ..These results also suggest that inflammatory responses induced by the activation of TLRs can be differentially modulated by types of dietary fatty acids. ..
  5. Goodson M, Jonas B, Privalsky M. Alternative mRNA splicing of SMRT creates functional diversity by generating corepressor isoforms with different affinities for different nuclear receptors. J Biol Chem. 2005;280:7493-503 pubmed
    ..Our results suggest that differential mRNA splicing serves to customize corepressor function in different cells, allowing the transcriptional properties of nuclear receptors to be adapted to different contexts. ..
  6. Zhang Z, Ober J, Kliebenstein D. The gene controlling the quantitative trait locus EPITHIOSPECIFIER MODIFIER1 alters glucosinolate hydrolysis and insect resistance in Arabidopsis. Plant Cell. 2006;18:1524-36 pubmed
    ..The glucosinolate hydrolysis profile change influenced by ESM1 is associated with the ability to deter herbivory by Trichoplusia ni. This gene could provide unique approaches toward improving human nutrition. ..
  7. Su Y, Lagarias J. Light-independent phytochrome signaling mediated by dominant GAF domain tyrosine mutants of Arabidopsis phytochromes in transgenic plants. Plant Cell. 2007;19:2124-39 pubmed
    ..We conclude that the universally conserved GAF domain Tyr residue, with which the bilin chromophore is intimately associated, performs a critical role in coupling light perception to signal transduction by plant phytochromes. ..
  8. Rosen M, Privalsky M. Thyroid hormone receptor mutations found in renal clear cell carcinomas alter corepressor release and reveal helix 12 as key determinant of corepressor specificity. Mol Endocrinol. 2009;23:1183-92 pubmed publisher