Experts and Doctors on animals in Berkeley, California, United States

Summary

Locale: Berkeley, California, United States
Topic: animals

Top Publications

  1. Moon A, Janmey P, Louie K, Drubin D. Cofilin is an essential component of the yeast cortical cytoskeleton. J Cell Biol. 1993;120:421-35 pubmed
    ..Thus, cofilin and Abp1p are structurally related but functionally distinct components of the yeast membrane cytoskeleton. ..
  2. Kramer L, Bowen M, Hardy J, Reeves W, Presser S, Eldridge B. Vector competence of alpine, Central Valley, and coastal mosquitoes (Diptera: Culicidae) from California for Jamestown Canyon virus. J Med Entomol. 1993;30:398-406 pubmed
    ..Alpine strains of JC virus also were transmitted vertically by Ae. tahoensis, Ae. washinoi, and Ae. squamiger following parenteral infection of females. ..
  3. Goodwill K, Sabatier C, Stevens R. Crystal structure of tyrosine hydroxylase with bound cofactor analogue and iron at 2.3 A resolution: self-hydroxylation of Phe300 and the pterin-binding site. Biochemistry. 1998;37:13437-45 pubmed
    ..This structure represents the first report of close interactions between pterin and iron in an enzyme active site. ..
  4. Nauman E, Satcher R, Keaveny T, Halloran B, Bikle D. Osteoblasts respond to pulsatile fluid flow with short-term increases in PGE(2) but no change in mineralization. J Appl Physiol (1985). 2001;90:1849-54 pubmed
    ..Our results indicate that short-term changes in PGE(2) levels caused by pulsatile fluid flow are not associated with long-term changes in proliferation or mineralization of bone cells...
  5. Chiou S, Yoo J, Loh K, Guzman R, Gopinath G, Rajkumar L, et al. Identification of rat mammary tumor-1 gene (RMT-1), which is highly expressed in rat mammary tumors. Cancer Lett. 2001;174:45-55 pubmed
    ..However, whether or not RMT-1 gene has a functional role in these processes remains to be investigated. ..
  6. Wintz H, Vulpe C. Plant copper chaperones. Biochem Soc Trans. 2002;30:732-5 pubmed
    ..In this paper we present our current knowledge of copper chaperones in A. thaliana based on the information available from the complete sequence of its genome. ..
  7. Toledo Ortiz G, Huq E, Quail P. The Arabidopsis basic/helix-loop-helix transcription factor family. Plant Cell. 2003;15:1749-70 pubmed
    ..These data are consistent, in principle, with the operation of this combinatorial mechanism in Arabidopsis. ..
  8. Williams B, Brodie E. A resistant predator and its toxic prey: persistence of newt toxin leads to poisonous (not venomous) snakes. J Chem Ecol. 2004;30:1901-19 pubmed
    ..Three weeks after eating one newt, snakes contained an average of 42 microg of TTX in the liver. This amount could severely incapacitate or kill avian predators, and mammalian predators may be negatively affected as well...
  9. Alioto T, Ngai J. The odorant receptor repertoire of teleost fish. BMC Genomics. 2005;6:173 pubmed
    ..In addition, our calculations of the ratios of non-synonymous to synonymous codon substitutions among more recently expanding OR subgroups in zebrafish implicate residues that may be involved in odorant binding. ..

More Information

Publications893 found, 100 shown here

  1. Uchida Y, Casali N, White A, Morici L, Kendall L, Riley L. Accelerated immunopathological response of mice infected with Mycobacterium tuberculosis disrupted in the mce1 operon negative transcriptional regulator. Cell Microbiol. 2007;9:1275-83 pubmed
    ..mce1 operon may homeostatically regulate the cell wall architecture in vivo that elicits a steady-state granuloma tissue response permitting M. tuberculosis to establish a long-term infection. ..
  2. Christiaen L, Jaszczyszyn Y, Kerfant M, Kano S, Thermes V, Joly J. Evolutionary modification of mouth position in deuterostomes. Semin Cell Dev Biol. 2007;18:502-11 pubmed
    ..We illustrate these morphogenetic movements by means of morphological data obtained by the confocal imaging of ascidian tailbud embryos, and provide a table for determining the tailbud stages of this model organism...
  3. Koerber J, Jang J, Schaffer D. DNA shuffling of adeno-associated virus yields functionally diverse viral progeny. Mol Ther. 2008;16:1703-9 pubmed publisher
    ..Thus, directed evolution can potentially yield unlimited numbers of new AAV variants with novel gene-delivery properties, and subsequent analysis of these variants can further extend basic knowledge of AAV biology. ..
  4. Cline T, Dorsett M, Sun S, Harrison M, Dines J, Sefton L, et al. Evolution of the Drosophila feminizing switch gene Sex-lethal. Genetics. 2010;186:1321-36 pubmed publisher
    ..The potential evolutionary relevance of these nonessential functions is discussed...
  5. Nice T, Deng W, Coscoy L, Raulet D. Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase. J Immunol. 2010;185:5369-76 pubmed publisher
    ..These results identify Mult1 as a target for the MARCH family of E3 ligases and show that induction of Mult1 in response to heat shock is due to regulated association with its E3 ligases. ..
  6. Van de Bittner G, Dubikovskaya E, Bertozzi C, Chang C. In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter. Proc Natl Acad Sci U S A. 2010;107:21316-21 pubmed publisher
    ..The ability to chemoselectively monitor H(2)O(2) fluxes in real time in living animals offers opportunities to dissect H(2)O(2)'s disparate contributions to health, aging, and disease. ..
  7. Barkis W, Ford K, Feller M. Non-cell-autonomous factor induces the transition from excitatory to inhibitory GABA signaling in retina independent of activity. Proc Natl Acad Sci U S A. 2010;107:22302-7 pubmed publisher
    ..Thus, a diffusible signal that acts independent of local circuit activity regulates the maturation of GABAergic inhibition in mouse RGCs. ..
  8. Deino A. (40)Ar/(39)Ar dating of Bed I, Olduvai Gorge, Tanzania, and the chronology of early Pleistocene climate change. J Hum Evol. 2012;63:251-73 pubmed publisher
    ..The extreme wet/dry climate shifts seen in the upper part of Bed I occur during an Earth-orbital eccentricity maximum, similar to episodic lake expansions documented elsewhere in the East African Rift during the Neogene. ..
  9. Revzen S, Burden S, Moore T, Mongeau J, Full R. Instantaneous kinematic phase reflects neuromechanical response to lateral perturbations of running cockroaches. Biol Cybern. 2013;107:179-200 pubmed publisher
    ..Animals with eight or more legs might be more robust to lateral perturbations than hexapods...
  10. Oda M, Bielicki J, Ho T, Berger T, Rubin E, Forte T. Paraoxonase 1 overexpression in mice and its effect on high-density lipoproteins. Biochem Biophys Res Commun. 2002;290:921-7 pubmed
    ..Excess mPON1 also inhibited lipid hydroperoxide formation on HDL. These data strongly suggest that overexpression of mPON1 protects HDL integrity and function. ..
  11. Engqvist Goldstein A, Drubin D. Actin assembly and endocytosis: from yeast to mammals. Annu Rev Cell Dev Biol. 2003;19:287-332 pubmed
    ..In this review, we focus on progress made in elucidating the functions of the actin cytoskeleton in endocytosis. ..
  12. Rachowicz L, Vredenburg V. Transmission of Batrachochytrium dendrobatidis within and between amphibian life stages. Dis Aquat Organ. 2004;61:75-83 pubmed
    ..In addition, we provide guidelines for visually detecting B. dendrobatidis in R. muscosa tadpoles, which may be useful in other affected species. Field surveys of infected and uninfected populations verify this identification technique...
  13. Grenier J, Greenberg R. A biogeographic pattern in sparrow bill morphology: parallel adaptation to tidal marshes. Evolution. 2005;59:1588-95 pubmed
    ..We, therefore, speculate that tidal marsh ecosystems are likely settings for ecological speciation...
  14. Hoskins R, Landolin J, Brown J, Sandler J, Takahashi H, Lassmann T, et al. Genome-wide analysis of promoter architecture in Drosophila melanogaster. Genome Res. 2011;21:182-92 pubmed publisher
    ..Our results contribute to the emerging view that core promoters are functionally diverse and control patterning of gene expression in Drosophila and mammals. ..
  15. Kimmel B, Heberlein U, Rubin G. The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype. Genes Dev. 1990;4:712-27 pubmed
    ..Taken together with previous analyses of the rough mutant phenotype, these results suggest that the normal role of rough is to establish the unique cell identity of photoreceptors R2 and R5. ..
  16. Baker N, Mlodzik M, Rubin G. Spacing differentiation in the developing Drosophila eye: a fibrinogen-related lateral inhibitor encoded by scabrous. Science. 1990;250:1370-7 pubmed
    ..It is proposed that the sca locus encodes a lateral inhibitor of R8 differentiation. The roles of the Drosophila EGF-receptor homologue (DER) and Notch genes in this process were also investigated. ..
  17. Kimbrell D, Tojo S, Alexander S, Brown E, Tobin S, Fristrom J. Regulation of larval cuticle protein gene expression in Drosophila melanogaster. Dev Genet. 1989;10:198-209 pubmed
    ..The region between -252 bp and -515 bp may be essential for any expression of LCP-2. Additionally, the region between -515 bp and -795 bp appears to be required for the normal level of expression of the LCP-2 gene. ..
  18. Neufeld T, Rubin G. The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins. Cell. 1994;77:371-9 pubmed
    ..Our results suggest that this class of proteins is involved in aspects of cytokinesis that have been conserved between flies and yeast. ..
  19. Garbe J, Yang E, Fristrom J. IMP-L2: an essential secreted immunoglobulin family member implicated in neural and ectodermal development in Drosophila. Development. 1993;119:1237-50 pubmed
    ..Expression of IMP-L2 protein in neuronal cells suggests a role in the normal development of the nervous system but no severe morphological abnormalities have been detected in IMP-L2 null embryos. ..
  20. Mian I, Moser M, Holley W, Chatterjee A. Statistical modelling and phylogenetic analysis of a deaminase domain. J Comput Biol. 1998;5:57-72 pubmed
    ..Some bacterial and eucaryotic DM domains form distinct branches in the phylogenetic tree suggesting the existence of common, novel substrates. ..
  21. Chambers C, Sullivan T, Truong T, Allison J. Secondary but not primary T cell responses are enhanced in CTLA-4-deficient CD8+ T cells. Eur J Immunol. 1998;28:3137-43 pubmed
    ..These results suggest that CTLA-4 regulates antigen-specific memory CD8+ T cell responses. ..
  22. Lin M, Napoli J. cDNA cloning and expression of a human aldehyde dehydrogenase (ALDH) active with 9-cis-retinal and identification of a rat ortholog, ALDH12. J Biol Chem. 2000;275:40106-12 pubmed
    ..Intense ALDH12 mRNA expression in adult and fetal liver and kidney, two organs that reportedly have relatively high concentrations of 9-cis-retinol, reinforces this notion. ..
  23. Lai E, Roegiers F, Qin X, Jan Y, Rubin G. The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta. Development. 2005;132:2319-32 pubmed
    ..We conclude that ubiquitination of Delta and Serrate by Neuralized and D-mib is an obligate feature of DSL ligand activation throughout Drosophila development. ..
  24. Dill K, Amacher S. tortuga refines Notch pathway gene expression in the zebrafish presomitic mesoderm at the post-transcriptional level. Dev Biol. 2005;287:225-36 pubmed
  25. McGirr K, Buehuring G. Tax & rex: overlapping genes of the Deltaretrovirus group. Virus Genes. 2006;32:229-39 pubmed
  26. Watari Goshima N, Ogura K, Wolf F, Goshima Y, Garriga G. C. elegans VAB-8 and UNC-73 regulate the SAX-3 receptor to direct cell and growth-cone migrations. Nat Neurosci. 2007;10:169-76 pubmed
  27. Amin R, Cado D, Nolla H, Huang D, Shinton S, Zhou Y, et al. Biallelic, ubiquitous transcription from the distal germline Ig{kappa} locus promoter during B cell development. Proc Natl Acad Sci U S A. 2009;106:522-7 pubmed publisher
    ..Allelic exclusion of the Igkappa locus thus occurs at the level of rearrangement, but not germline transcription. ..
  28. Sletten E, Bertozzi C. Bioorthogonal chemistry: fishing for selectivity in a sea of functionality. Angew Chem Int Ed Engl. 2009;48:6974-98 pubmed publisher
    ..Herein we describe the bioorthogonal chemical reactions developed to date and how they can be used to study biomolecules. ..
  29. Ramírez S, Eltz T, Fritzsch F, Pemberton R, Pringle E, Tsutsui N. Intraspecific geographic variation of fragrances acquired by orchid bees in native and introduced populations. J Chem Ecol. 2010;36:873-84 pubmed publisher
    ..By comparing incidence values and consistency indices across populations, we identify putative functional compounds that may play an important role in courtship signaling in this species of orchid bee. ..
  30. Doyon J, Zeitler B, Cheng J, Cheng A, Cherone J, Santiago Y, et al. Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells. Nat Cell Biol. 2011;13:331-7 pubmed publisher
    ..Our study establishes that ZFN-mediated genome editing is a robust tool for expressing protein fusions at endogenous levels to faithfully report subcellular localization and dynamics. ..
  31. Dalkara D, Byrne L, Lee T, Hoffmann N, Schaffer D, Flannery J. Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV9. Gene Ther. 2012;19:176-81 pubmed publisher
    ..This approach provides a new methodology for the development of retinal gene therapies or creation of animal models of neurodegenerative disease. ..
  32. Williams K, Sukupolvi Petty S, Beltramello M, Johnson S, Sallusto F, Lanzavecchia A, et al. Therapeutic efficacy of antibodies lacking Fc? receptor binding against lethal dengue virus infection is due to neutralizing potency and blocking of enhancing antibodies [corrected]. PLoS Pathog. 2013;9:e1003157 pubmed publisher
    ..These studies provide new insight into the biology of DENV pathogenesis and the requirements for antibodies to treat lethal DENV disease. ..
  33. Wilt F, Killian C, Croker L, Hamilton P. SM30 protein function during sea urchin larval spicule formation. J Struct Biol. 2013;183:199-204 pubmed publisher
    ..This surprising result requires re-thinking about the role of these, and possibly other occluded matrix proteins. ..
  34. Huss M, Chum H, Chang A, Jampachairsi K, Pacharinsak C. The Physiologic Effects of Isoflurane, Sevoflurane, and Hypothermia Used for Anesthesia in Neonatal Rats (Rattus norvegicus). J Am Assoc Lab Anim Sci. 2016;55:83-8 pubmed
    ..We conclude that both isoflurane and sevoflurane anesthesia maintain physiologic parameters (HR, RR, %SpO2) more consistently than does hypothermia anesthesia in 4-d-old rat pups. ..
  35. Putnam N, O Connell B, Stites J, Rice B, Blanchette M, Calef R, et al. Chromosome-scale shotgun assembly using an in vitro method for long-range linkage. Genome Res. 2016;26:342-50 pubmed publisher
    ..With a single library and one lane of Illumina HiSeq sequencing, we increased the scaffold N50 of the American alligator from 508 kbp to 10 Mbp. ..
  36. Saha S, Hosmani P, Villalobos Ayala K, Miller S, Shippy T, Flores M, et al. Improved annotation of the insect vector of citrus greening disease: biocuration by a diverse genomics community. Database (Oxford). 2017;2017: pubmed publisher
    ..https://citrusgreening.org/...
  37. Meszaros K, Aberle S, White M, Parent J. Immunoreactivity and bioactivity of lipopolysaccharide-binding protein in normal and heat-inactivated sera. Infect Immun. 1995;63:363-5 pubmed
    ..The commonly practiced heat inactivation of human serum (56 degrees C, 30 min) resulted in a 70% loss of bioactivity, which caused an apparent decrease in the potency of LPS. ..
  38. Cutforth T, Rubin G. Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila. Cell. 1994;77:1027-36 pubmed
    ..Together, these data support a role for Hsp90 proteins in tyrosine kinase regulation and suggest that signals promoting neuronal differentiation may involve cell cycle control. ..
  39. Tan A, Wake D. MtDNA phylogeography of the California newt, Taricha torosa (Caudata, Salamandridae). Mol Phylogenet Evol. 1995;4:383-94 pubmed
    ..8% divergence per million years or 0.01 maximum likelihood distance per million years). Phylogenetic implications of mtDNA sequence variation for evolution and biogeography of the T. torosa species complex are discussed...
  40. Weier H, George C, Lersch R, Breitweser S, Cheng J, Samuel C. Assignment of the RNA-specific adenosine deaminase gene (Adar) to mouse chromosome 3F2 by in situ hybridization. Cytogenet Cell Genet. 2000;89:214-5 pubmed
  41. Henrie M, Kurimasa A, Burma S, Menissier de Murcia J, de Murcia G, Li G, et al. Lethality in PARP-1/Ku80 double mutant mice reveals physiological synergy during early embryogenesis. DNA Repair (Amst). 2003;2:151-8 pubmed
  42. Tupy J, Bailey A, Dailey G, Evans Holm M, Siebel C, Misra S, et al. Identification of putative noncoding polyadenylated transcripts in Drosophila melanogaster. Proc Natl Acad Sci U S A. 2005;102:5495-500 pubmed
    ..We show that the expression of many of these transcripts is conserved in other Drosophila species, indicating that they have important biological functions. ..
  43. Ro D, Paradise E, Ouellet M, Fisher K, Newman K, Ndungu J, et al. Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature. 2006;440:940-3 pubmed
    ..annua, yield optimization and industrial scale-up will be required to raise artemisinic acid production to a level high enough to reduce artemisinin combination therapies to significantly below their current prices. ..
  44. Dalkara D, Kolstad K, Caporale N, Visel M, Klimczak R, Schaffer D, et al. Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous. Mol Ther. 2009;17:2096-102 pubmed publisher
    ..These findings may help avoid limitations, risks, and damage associated with subretinal injections currently necessary for clinical gene therapy. ..
  45. Leedom A, Sullivan A, Dong B, Lau D, Gronert K. Endogenous LXA4 circuits are determinants of pathological angiogenesis in response to chronic injury. Am J Pathol. 2010;176:74-84 pubmed publisher
    ..In summary, our findings and the prominent expression of 15-LOX and ALX in epithelial cells and macrophages place the LXA(4) circuit as an endogenous regulator of pathological angiogenesis. ..
  46. Miller K, Karr J, Marqusee S. A hinge region cis-proline in ribonuclease A acts as a conformational gatekeeper for C-terminal domain swapping. J Mol Biol. 2010;400:567-78 pubmed publisher
  47. Brandley M, Wang Y, Guo X, de Oca A, Fería Ortíz M, Hikida T, et al. Accommodating heterogenous rates of evolution in molecular divergence dating methods: an example using intercontinental dispersal of Plestiodon (Eumeces) lizards. Syst Biol. 2011;60:3-15 pubmed publisher
    ..Analyses that best capture the rate of evolution in the combined data set infer that this exchange occurred via Beringia ?18.0-30 Ma. ..
  48. Richner J, Clyde K, Pezda A, Cheng B, Wang T, Kumar G, et al. Global mRNA degradation during lytic gammaherpesvirus infection contributes to establishment of viral latency. PLoS Pathog. 2011;7:e1002150 pubmed publisher
    ..These results highlight for the first time the importance of global mRNA degradation during a gammaherpesvirus infection and link an exclusively lytic phenomenon with downstream latency establishment. ..
  49. Sterling H, Prell J, Cassou C, Williams E. Protein conformation and supercharging with DMSO from aqueous solution. J Am Soc Mass Spectrom. 2011;22:1178-86 pubmed publisher
  50. Kintzer A, Tang I, Schawel A, Brown M, Krantz B. Anthrax toxin protective antigen integrates poly-?-D-glutamate and pH signals to sense the optimal environment for channel formation. Proc Natl Acad Sci U S A. 2012;109:18378-83 pubmed publisher
    ..Thus, ?-DPGA may function as a chemical cue, signaling that the local environment is appropriate for toxin assembly but inappropriate for channel formation. ..
  51. Fink A, Williams K, Harris E, Alvine T, Henderson T, Schiltz J, et al. Dengue virus specific IgY provides protection following lethal dengue virus challenge and is neutralizing in the absence of inducing antibody dependent enhancement. PLoS Negl Trop Dis. 2017;11:e0005721 pubmed publisher
    ..These observations provide evidence for the potential therapeutic applications of goose-derived anti-DENV2 IgY. ..
  52. Irwin D, White R, Wilson A. Characterization of the cow stomach lysozyme genes: repetitive DNA and concerted evolution. J Mol Evol. 1993;37:355-66 pubmed
    ..This model of concerted evolution would allow the shuffling of exon-sized pieces of information between genes, a phenomenon that may have aided in the early adaptive evolution of stomach lysozyme. ..
  53. Garrow T, Brenner A, Whitehead V, Chen X, Duncan R, Korenberg J, et al. Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization. J Biol Chem. 1993;268:11910-6 pubmed
    ..The high degree of nucleotide sequence identity between the two isozymes, and the presence of keratin genes in both chromosomal regions, is consistent with these regions of chromosome 12 and 17 arising by a duplication event. ..
  54. Remus D, Beall E, Botchan M. DNA topology, not DNA sequence, is a critical determinant for Drosophila ORC-DNA binding. EMBO J. 2004;23:897-907 pubmed
  55. Deato M, Tjian R. Switching of the core transcription machinery during myogenesis. Genes Dev. 2007;21:2137-49 pubmed
    ..Although this drastic but parsimonious transcriptional switch had previously escaped our attention, it may represent a more general mechanism for regulating cell type-specific terminal differentiation. ..
  56. Laughlin S, Baskin J, Amacher S, Bertozzi C. In vivo imaging of membrane-associated glycans in developing zebrafish. Science. 2008;320:664-7 pubmed publisher
    ..Using a multicolor detection strategy, we performed a spatiotemporal analysis of glycan expression and trafficking and identified patterns that would be undetectable with conventional molecular imaging approaches. ..
  57. Rosenblum E, Stajich J, Maddox N, Eisen M. Global gene expression profiles for life stages of the deadly amphibian pathogen Batrachochytrium dendrobatidis. Proc Natl Acad Sci U S A. 2008;105:17034-9 pubmed publisher
    ..Finally we discuss the challenges inherent in developing a molecular toolkit for chytrids, a basal fungal lineage separated by vast phylogenetic distance from other well characterized fungi...
  58. Gullberg G, Reutter B, Sitek A, Maltz J, Budinger T. Dynamic single photon emission computed tomography--basic principles and cardiac applications. Phys Med Biol. 2010;55:R111-91 pubmed publisher
  59. Vose S, Fujioka K, Gulevich A, Lin A, Holland N, Casida J. Cellular function of neuropathy target esterase in lysophosphatidylcholine action. Toxicol Appl Pharmacol. 2008;232:376-83 pubmed publisher
    ..NTE therefore serves an important function in LPC homeostasis and action. ..
  60. McQueen A, Kanamaluru D, Yan K, Gray N, Wu L, Li M, et al. The C-terminal fibrinogen-like domain of angiopoietin-like 4 stimulates adipose tissue lipolysis and promotes energy expenditure. J Biol Chem. 2017;292:16122-16134 pubmed publisher
    ..We conclude that separating the FLD from the CCD-mediated LPL-inhibitory activity of full-length Angptl4 reveals lipolytic and thermogenic properties with therapeutic relevance to obesity and diabetes. ..
  61. Kemal C, Casida J. Coenzyme A esters of 2-aryloxyphenoxypropionate herbicides and 2-arylpropionate antiinflammatory drugs are potent and stereoselective inhibitors of rat liver acetyl-CoA carboxylase. Life Sci. 1992;50:533-40 pubmed
    ..These results suggest that some of the biological effects of these herbicides and antiinflammatory drugs in animals may be due to the inhibition of acetyl-CoA carboxylase by their acyl-CoA derivatives. ..
  62. Treisman J, Lai Z, Rubin G. Shortsighted acts in the decapentaplegic pathway in Drosophila eye development and has homology to a mouse TGF-beta-responsive gene. Development. 1995;121:2835-45 pubmed
    ..shortsighted encodes a cytoplasmic leucine zipper protein with homology to a mouse gene, TSC-22, which is transcriptionally induced in response to TGF-beta. ..
  63. Lichtsteiner S, Tjian R. Synergistic activation of transcription by UNC-86 and MEC-3 in Caenorhabditis elegans embryo extracts. EMBO J. 1995;14:3937-45 pubmed
    ..These studies provide direct functional evidence for coordinated transcriptional activation by two C.elegans DNA binding proteins that have been defined genetically as regulators of gene expression during embryogenesis. ..
  64. Lambert K, Allen K, Sussex I. Cloning and characterization of an esophageal-gland-specific chorismate mutase from the phytoparasitic nematode Meloidogyne javanica. Mol Plant Microbe Interact. 1999;12:328-36 pubmed
    ..Therefore, we hypothesize that this CM is involved in allowing nematodes to parasitize plants. ..
  65. Chan R, Chan A, Jeon M, Wu T, Pasqualone D, Rougvie A, et al. Chromosome cohesion is regulated by a clock gene paralogue TIM-1. Nature. 2003;423:1002-9 pubmed
    ..On the basis of comparisons between TIMELESS homologues in worms, flies and mice, we propose that chromosome cohesion, rather than circadian clock regulation, is the ancient and conserved function for TIMELESS-like proteins. ..
  66. Erives A, Levine M. Coordinate enhancers share common organizational features in the Drosophila genome. Proc Natl Acad Sci U S A. 2004;101:3851-6 pubmed
    ..Organized binding sites should facilitate the identification of regulatory codes that link primary DNA sequence information with predicted patterns of gene activity. ..
  67. Goltsev Y, Hsiong W, Lanzaro G, Levine M. Different combinations of gap repressors for common stripes in Anopheles and Drosophila embryos. Dev Biol. 2004;275:435-46 pubmed
    ..We discuss the evolution of separate stripe enhancers in the eve loci of different dipterans. ..
  68. Conant C, Stephens R. Chlamydia attachment to mammalian cells requires protein disulfide isomerase. Cell Microbiol. 2007;9:222-32 pubmed
    ..The cell line was also resistant to diphtheria toxin and required complemented cell-surface PDI for toxin entry. These data demonstrate that native PDI at the cell surface is required for effective chlamydial attachment and infectivity. ..
  69. Nakama L, King K, Abrahamsson S, Rempel D. Effect of repetition rate on the formation of microtears in tendon in an in vivo cyclical loading model. J Orthop Res. 2007;25:1176-84 pubmed
    ..The results suggest that repetition rate or number of loading cycles is associated with increased tendon microtears or fragility in a dose-response pattern. ..
  70. Ahmadian M, Duncan R, Varady K, Frasson D, Hellerstein M, Birkenfeld A, et al. Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity. Diabetes. 2009;58:855-66 pubmed publisher
    ..Desnutrin-mediated lipolysis promotes fatty acid oxidation and re-esterification within adipocytes. ..
  71. Calisi R, Bentley G. Lab and field experiments: are they the same animal?. Horm Behav. 2009;56:1-10 pubmed publisher
    ..Perhaps, just as study of individual variation has been gaining momentum in recent years, data from variation between experimental arenas can provide us with novel lines of research...
  72. Chtanova T, Han S, Schaeffer M, van Dooren G, Herzmark P, Striepen B, et al. Dynamics of T cell, antigen-presenting cell, and pathogen interactions during recall responses in the lymph node. Immunity. 2009;31:342-55 pubmed publisher
    ..Our results provide insight into cellular interactions during recall responses and suggest a mechanism of pathogen subversion of the immune response. ..
  73. Li J, Jiang C, Brown J, Huang H, Bickel P. Sparse linear modeling of next-generation mRNA sequencing (RNA-Seq) data for isoform discovery and abundance estimation. Proc Natl Acad Sci U S A. 2011;108:19867-72 pubmed publisher
    ..The SLIDE software package is available at https://sites.google.com/site/jingyijli/SLIDE.zip. ..
  74. Schulz D, Vassen L, Chow K, McWhirter S, Amin R, Moroy T, et al. Gfi1b negatively regulates Rag expression directly and via the repression of FoxO1. J Exp Med. 2012;209:187-99 pubmed publisher
    ..Together, our experiments show that Gfi family members are essential for normal B cell development and play an important role in modulating expression of the V(D)J recombinase. ..
  75. Libby T, Moore T, Chang Siu E, Li D, Cohen D, Jusufi A, et al. Tail-assisted pitch control in lizards, robots and dinosaurs. Nature. 2012;481:181-4 pubmed publisher
    ..Leaping lizards show that inertial control of body attitude can advance our understanding of appendage evolution and provide biological inspiration for the next generation of manoeuvrable search-and-rescue robots...
  76. Song R, Walentek P, Sponer N, Klimke A, Lee J, Dixon G, et al. miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110. Nature. 2014;510:115-20 pubmed publisher
    ..Altogether, our findings elucidate conserved cellular and molecular mechanisms through which miR-34/449 regulate motile ciliogenesis. ..
  77. Torres Duarte C, Ramos Torres K, Rahimoff R, Cherr G. Stage specific effects of soluble copper and copper oxide nanoparticles during sea urchin embryo development and their relation to intracellular copper uptake. Aquat Toxicol. 2017;189:134-141 pubmed publisher
    ..Results indicate that nano-CuO results in higher accumulation of copper inside of embryos and this intracellular copper is more persistent as compared to soluble copper. The possible implications later in development are discussed. ..
  78. Turker M, Grygoryev D, Lasarev M, Ohlrich A, Rwatambuga F, Johnson S, et al. Simulated space radiation-induced mutants in the mouse kidney display widespread genomic change. PLoS ONE. 2017;12:e0180412 pubmed publisher
    ..The level of genomic change produced by low fluence exposure to heavy ions is reminiscent of the extensive rearrangements seen in tumor genomes suggesting a potential initiation step in radiation carcinogenesis. ..
  79. Linn S. How many pols does it take to replicate nuclear DNA?. Cell. 1991;66:185-7 pubmed
  80. Irwin D, Wilson A. Concerted evolution of ruminant stomach lysozymes. Characterization of lysozyme cDNA clones from sheep and deer. J Biol Chem. 1990;265:4944-52 pubmed
  81. Vogel J, Morse R, Goodenow R. A novel H-2K splice form: predictions for other alternative H-2 splicing events. Immunogenetics. 1989;29:33-43 pubmed
    ..The features of this novel splice form served as the basis for predicting additional rare, alternative H-2 pre-mRNA splicing events that might produce functionally relevant microheterogeneity in the encoded H-2 gene products. ..
  82. Chui G, Linn S. Further characterization of HeLa DNA polymerase epsilon. J Biol Chem. 1995;270:7799-808 pubmed
  83. Poirier M, Xiao W, Macosko J, Chan C, Shin Y, Bennett M. The synaptic SNARE complex is a parallel four-stranded helical bundle. Nat Struct Biol. 1998;5:765-9 pubmed
    ..Based on these findings, we propose a parallel four-stranded coiled coil model for the structure of the synaptic SNARE complex. ..
  84. Pan D, Rubin G. Targeted expression of teashirt induces ectopic eyes in Drosophila. Proc Natl Acad Sci U S A. 1998;95:15508-12 pubmed
    ..Furthermore, teashirt and eyeless induce the expression of each other, suggesting that teashirt is part of the gene network that functions to specify eye identity. ..
  85. Duman J, Tyagarajan K, Kolsi M, Moore H, Forte J. Expression of rab11a N124I in gastric parietal cells inhibits stimulatory recruitment of the H+-K+-ATPase. Am J Physiol. 1999;277:C361-72 pubmed publisher
    ..We therefore conclude that rab11a is the prominent GTPase associated with gastric microsomes and that it plays a role in parietal cell activation. ..
  86. Swallow M, Wallin J, Sha W. B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha. Immunity. 1999;11:423-32 pubmed
    ..These data define a novel costimulatory ligand for T cells and suggest that induction of B7h by TNFalpha may function as a mechanism to directly augment recognition of self during inflammation. ..
  87. Rio D. Half-pint: alternative splicing in the Drosophila ovary. Mol Cell. 2002;9:456-7 pubmed
    ..A new study from the Schüpbach lab implicates a splicing factor, Half-pint, in the regulation of oogenesis in Drosophila. Through processing of the otu mRNA, Hfp appears to control both mitosis and RNA localization in the germline. ..
  88. Sousa W, Kennedy P, Mitchell B. Propagule size and predispersal damage by insects affect establishment and early growth of mangrove seedlings. Oecologia. 2003;135:564-75 pubmed
    ..Such differences are sufficiently large that they could influence the intensity and outcome of competitive interactions during forest regeneration...
  89. Withee J, Galligan B, Hawkins N, Garriga G. Caenorhabditis elegans WASP and Ena/VASP proteins play compensatory roles in morphogenesis and neuronal cell migration. Genetics. 2004;167:1165-76 pubmed
    ..In addition, our results provide the first example of an in vivo role for WASP family proteins in neuronal cell migrations and cytokinesis in metazoans. ..
  90. Wong J, Collins K. Telomerase RNA level limits telomere maintenance in X-linked dyskeratosis congenita. Genes Dev. 2006;20:2848-58 pubmed
    ..These findings support the significance of telomerase deficiency in the pathology of X-linked DC. ..
  91. Tomlin C, Axelrod J. Biology by numbers: mathematical modelling in developmental biology. Nat Rev Genet. 2007;8:331-40 pubmed
    ..By examining three developmental processes and corresponding mathematical models, this Review addresses the potential of mathematical modelling to help understand development. ..
  92. Bai Y, Trang P, Li H, Kim K, Zhou T, Liu F. Effective inhibition in animals of viral pathogenesis by a ribozyme derived from RNase P catalytic RNA. Proc Natl Acad Sci U S A. 2008;105:10919-24 pubmed publisher
    ..Our study examines the use of M1GS ribozymes for inhibition of gene expression in animals and demonstrates the utility of RNase P ribozymes for gene targeting applications in vivo. ..