Experts and Doctors on in Tucson, Arizona, United States

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Locale: Tucson, Arizona, United States
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Top Publications

  1. Lee H, Guo Y, Ohta M, Xiong L, Stevenson B, Zhu J. LOS2, a genetic locus required for cold-responsive gene transcription encodes a bi-functional enolase. EMBO J. 2002;21:2692-702 pubmed
    ..Our results demonstrate that cold-responsive gene transcription in plants is controlled by a bi-functional enolase. ..
  2. Ignatenko N, Gerner E. Regulation of the HIV1 long terminal repeat by mutant heat shock factor. Exp Cell Res. 2003;288:1-8 pubmed
    ..The ability of HSF1+ to suppress HIV1 promoter activity suggests that HSF1+ could serve as a tool for the treatment of AIDS. ..
  3. King T, Gardell L, Wang R, Vardanyan A, Ossipov M, Malan T, et al. Role of NK-1 neurotransmission in opioid-induced hyperalgesia. Pain. 2005;116:276-88 pubmed
    ..Understanding of sustained morphine-induced neurochemical changes will help identify approaches that limit the deleterious actions of opiates. ..
  4. Xie J, Herman D, Stiller C, Gardell L, Ossipov M, Lai J, et al. Cholecystokinin in the rostral ventromedial medulla mediates opioid-induced hyperalgesia and antinociceptive tolerance. J Neurosci. 2005;25:409-16 pubmed
    ..Prevention of opioid-dose escalation in chronic pain states by CCK receptor antagonism represents a potentially important strategy to limit unintended enhanced clinical pain and analgesic tolerance ..
  5. Larkindale J, Hall J, Knight M, Vierling E. Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance. Plant Physiol. 2005;138:882-97 pubmed
  6. Basha E, Friedrich K, Vierling E. The N-terminal arm of small heat shock proteins is important for both chaperone activity and substrate specificity. J Biol Chem. 2006;281:39943-52 pubmed publisher
    ..In total, results demonstrate that sHSP-substrate interactions are complex, likely involve multiple sites on the sHSP, and vary depending on substrate...
  7. Lee U, Rioflorido I, Hong S, Larkindale J, Waters E, Vierling E. The Arabidopsis ClpB/Hsp100 family of proteins: chaperones for stress and chloroplast development. Plant J. 2007;49:115-27 pubmed
    ..Thus, in plants, the function of ClpB/Hsp100 proteins is not restricted to heat stress, but a specific member of the family provides housekeeping functions that are essential to chloroplast development. ..
  8. Dunbar H, Wilson A, Ferguson N, Moran N. Aphid thermal tolerance is governed by a point mutation in bacterial symbionts. PLoS Biol. 2007;5:e96 pubmed
    ..Other cases in which symbiont microevolution has a major effect on host ecological tolerance are likely to be widespread because of the high mutation rates of symbiotic bacteria and their crucial roles in host metabolism and development...
  9. Larkindale J, Vierling E. Core genome responses involved in acclimation to high temperature. Plant Physiol. 2008;146:748-61 pubmed

Scientific Experts

Detail Information

Publications9

  1. Lee H, Guo Y, Ohta M, Xiong L, Stevenson B, Zhu J. LOS2, a genetic locus required for cold-responsive gene transcription encodes a bi-functional enolase. EMBO J. 2002;21:2692-702 pubmed
    ..Our results demonstrate that cold-responsive gene transcription in plants is controlled by a bi-functional enolase. ..
  2. Ignatenko N, Gerner E. Regulation of the HIV1 long terminal repeat by mutant heat shock factor. Exp Cell Res. 2003;288:1-8 pubmed
    ..The ability of HSF1+ to suppress HIV1 promoter activity suggests that HSF1+ could serve as a tool for the treatment of AIDS. ..
  3. King T, Gardell L, Wang R, Vardanyan A, Ossipov M, Malan T, et al. Role of NK-1 neurotransmission in opioid-induced hyperalgesia. Pain. 2005;116:276-88 pubmed
    ..Understanding of sustained morphine-induced neurochemical changes will help identify approaches that limit the deleterious actions of opiates. ..
  4. Xie J, Herman D, Stiller C, Gardell L, Ossipov M, Lai J, et al. Cholecystokinin in the rostral ventromedial medulla mediates opioid-induced hyperalgesia and antinociceptive tolerance. J Neurosci. 2005;25:409-16 pubmed
    ..Prevention of opioid-dose escalation in chronic pain states by CCK receptor antagonism represents a potentially important strategy to limit unintended enhanced clinical pain and analgesic tolerance ..
  5. Larkindale J, Hall J, Knight M, Vierling E. Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance. Plant Physiol. 2005;138:882-97 pubmed
  6. Basha E, Friedrich K, Vierling E. The N-terminal arm of small heat shock proteins is important for both chaperone activity and substrate specificity. J Biol Chem. 2006;281:39943-52 pubmed publisher
    ..In total, results demonstrate that sHSP-substrate interactions are complex, likely involve multiple sites on the sHSP, and vary depending on substrate...
  7. Lee U, Rioflorido I, Hong S, Larkindale J, Waters E, Vierling E. The Arabidopsis ClpB/Hsp100 family of proteins: chaperones for stress and chloroplast development. Plant J. 2007;49:115-27 pubmed
    ..Thus, in plants, the function of ClpB/Hsp100 proteins is not restricted to heat stress, but a specific member of the family provides housekeeping functions that are essential to chloroplast development. ..
  8. Dunbar H, Wilson A, Ferguson N, Moran N. Aphid thermal tolerance is governed by a point mutation in bacterial symbionts. PLoS Biol. 2007;5:e96 pubmed
    ..Other cases in which symbiont microevolution has a major effect on host ecological tolerance are likely to be widespread because of the high mutation rates of symbiotic bacteria and their crucial roles in host metabolism and development...
  9. Larkindale J, Vierling E. Core genome responses involved in acclimation to high temperature. Plant Physiol. 2008;146:748-61 pubmed