Experts and Doctors on humans in Northport, Alabama, United States

Summary

Locale: Northport, Alabama, United States
Topic: humans

Top Publications

  1. Peress N, Fleit H, Perillo E, Kuljis R, Pezzullo C. Identification of Fc gamma RI, II and III on normal human brain ramified microglia and on microglia in senile plaques in Alzheimer's disease. J Neuroimmunol. 1993;48:71-9 pubmed
    ..These findings suggest that intrinsic Fc gamma R may play an important role in normal and disordered immune-related processes in the brain. They support the idea that microglia are brain macrophages. ..
  2. Choi E, Zmarlicka M, Ehret M. Vilazodone: a novel antidepressant. Am J Health Syst Pharm. 2012;69:1551-7 pubmed publisher
  3. Hasaneen N, Cao J, Pulkoski Gross A, Zucker S, Foda H. Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) promotes lung fibroblast proliferation, survival and differentiation to myofibroblasts. Respir Res. 2016;17:17 pubmed publisher
    ..EMMPRIN overexpression induces an anti-apoptotic and pro-fibrotic phenotype in lung fibroblasts that may contribute to the persistent fibro-proliferative state seen in IPF. ..
  4. Yeh S, Schuster M. Megestrol acetate in cachexia and anorexia. Int J Nanomedicine. 2006;1:411-6 pubmed
    ..A review of general usage and potential side-effects are discussed. A theory that the newly approved nanocrystal formation of MA can better deliver this potent medication for treatment will also be reviewed. ..
  5. Graber M, Tompkins D, Holland J. Resources medical students use to derive a differential diagnosis. Med Teach. 2009;31:522-7 pubmed
    ..Medical education needs to adapt to this reality, and address the need to teach future clinicians how to use these tools to advantage. ..
  6. Yeh S, DeGuzman B, Kramer T. Reversal of COPD-associated weight loss using the anabolic agent oxandrolone. Chest. 2002;122:421-8 pubmed
    ..Weight gain is primarily lean body mass. Oxandrolone was relatively well tolerated and, therefore, should be a consideration in the comprehensive management of patients with COPD and weight loss. ..
  7. Garcia Barros M, Coant N, Truman J, Snider A, Hannun Y. Sphingolipids in colon cancer. Biochim Biophys Acta. 2014;1841:773-82 pubmed publisher
    ..This article is part of a Special Issue entitled New Frontiers in Sphingolipid Biology. ..
  8. Ray K, Moss M, Franklin J, Weaver C, Higginbotham J, Song Y, et al. Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia. Oncogene. 2014;33:823-31 pubmed publisher
    ..These findings establish the importance of oncogenic synergy in cancer initiation and promotion, and establish a molecular link between inflammation and the earliest stages of tumor induction. ..
  9. Arvanian V. Role of neurotrophins in spinal plasticity and locomotion. Curr Pharm Des. 2013;19:4509-16 pubmed
    ..The findings summarized here indicate that neurotrophins have translational research potential for SCI repair, most likely as an essential component of combination therapy. ..

More Information

Publications18

  1. Gold A. Functional somatic syndromes, anxiety disorders and the upper airway: a matter of paradigms. Sleep Med Rev. 2011;15:389-401 pubmed publisher
    ..Finally, building upon an existing paradigm of neural sensitization, sleep disordered breathing is linked to functional somatic syndromes and anxiety disorders through chronic activation of the hypothalamic-pituitary-adrenal axis. ..
  2. Gold A, Gold M, Harris K, Espeleta V, Amin M, Broderick J. Hypersomnolence, insomnia and the pathophysiology of upper airway resistance syndrome. Sleep Med. 2008;9:675-83 pubmed
    ..A physical model is proposed to account for the excess somnolence in UARS relative to expectations and the increasing frequency of sleep-onset insomnia along the continuum from severe OSA/H to UARS. ..
  3. Amin M, Gold M, Broderick J, Gold A. The effect of nasal continuous positive airway pressure on the symptoms of Gulf War illness. Sleep Breath. 2011;15:579-87 pubmed publisher
    ..004), sleep quality (41%; p = 0.0003), physical health (34%; p = 0.0003), and mental health (16%; p = 0.03). Our findings in this pilot study suggest that nasal CPAP may greatly improve symptoms in veterans with GWI and SDB. ..
  4. Zucker S, Cao J. Selective matrix metalloproteinase (MMP) inhibitors in cancer therapy: ready for prime time?. Cancer Biol Ther. 2009;8:2371-3 pubmed
  5. Rollo E, Hempson S, Bansal A, Tsao E, Habib I, Rittling S, et al. The cytokine osteopontin modulates the severity of rotavirus diarrhea. J Virol. 2005;79:3509-16 pubmed
    ..Rotavirus infection of intestinal epithelial cells and murine intestine caused marked increases in OPN mRNA levels and secreted OPN protein. OPN-deficient mice suffered prolonged disease. ..
  6. Cohen I, Lin R, Ballou L. Acquired long QT syndrome and phosphoinositide 3-kinase. Trends Cardiovasc Med. 2017;27:451-459 pubmed publisher
    ..Reduced PI3K signaling may also play a role in aLQTS associated with diabetes. Drug safety testing to identify aLQTS risk may be improved by examining PI3K-dependent effects that develop over time. ..
  7. Yeh S, Lovitt S, Schuster M. Usage of megestrol acetate in the treatment of anorexia-cachexia syndrome in the elderly. J Nutr Health Aging. 2009;13:448-54 pubmed
  8. Pan J, Sun Y, Jiang Y, Bott A, Jaber N, Dou Z, et al. TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis. Mol Cell. 2016;61:720-733 pubmed publisher
    ..Therefore, TRIM21 plays an essential role in p62-regulated redox homeostasis and may be a viable target for treating pathological conditions resulting from oxidative damage. ..
  9. Nelson V, Negrón A, Reid I, Thomas J, Yang L, Lin R, et al. Loss of PI3K p110? in the Adipose Tissue Results in Infertility and Delayed Puberty Onset in Male Mice. Biomed Res Int. 2017;2017:3756089 pubmed publisher
    ..We propose that chronic hyperleptinemia contributes to the negative impact that disrupting PI3K signaling in adipocytes has on puberty onset, steroidogenesis, and fertility in males. ..