Genomes and Genes
Experts and Doctors on humans in Kampala, Central Region, Uganda
Locale: Kampala, Central Region, Uganda
Publications390 found, 100 shown here
- Mendenhall E, De Silva M, Hanlon C, Petersen I, Shidhaye R, Jordans M, et al. Acceptability and feasibility of using non-specialist health workers to deliver mental health care: stakeholder perceptions from the PRIME district sites in Ethiopia, India, Nepal, South Africa, and Uganda. Soc Sci Med. 2014;118:33-42 pubmed publisher
- Lamorde M, Byakika Kibwika P, Okaba Kayom V, Flaherty J, Boffito M, Namakula R, et al. Suboptimal nevirapine steady-state pharmacokinetics during intrapartum compared with postpartum in HIV-1-seropositive Ugandan women. J Acquir Immune Defic Syndr. 2010;55:345-50 pubmed publisher..The long-term impact of intermittent suboptimal nevirapine concentrations during pregnancy is unknown. ..
- Bangirana P, Allebeck P, Boivin M, John C, Page C, Ehnvall A, et al. Cognition, behaviour and academic skills after cognitive rehabilitation in Ugandan children surviving severe malaria: a randomised trial. BMC Neurol. 2011;11:96 pubmed publisher..Larger trials with follow-up after a few years are needed to investigate whether the observed benefits are sustained. ISRCTN: ISRCTN53183087. ..
- Muhumuza S, Olsen A, Katahoire A, Nuwaha F. Uptake of preventive treatment for intestinal schistosomiasis among school children in Jinja district, Uganda: a cross sectional study. PLoS ONE. 2013;8:e63438 pubmed publisher..Fear of side effects of praziquantel, lack of knowledge about schistosomiasis transmission and prevention and lack of teacher support are some of the major factors associated with low uptake. ..
- Baron E, Hanlon C, Mall S, Honikman S, Breuer E, Kathree T, et al. Maternal mental health in primary care in five low- and middle-income countries: a situational analysis. BMC Health Serv Res. 2016;16:53 pubmed publisher..Limited evidence on effective psychosocial interventions was also noted, and must be addressed for mental health programmes, such as PRIME, to implement feasible and effective services. ..
- Colebunders R, Hendy A, Mokili J, Wamala J, Kaducu J, Kur L, et al. Nodding syndrome and epilepsy in onchocerciasis endemic regions: comparing preliminary observations from South Sudan and the Democratic Republic of the Congo with data from Uganda. BMC Res Notes. 2016;9:182 pubmed publisher..Blackflies may play a key role in the transmission of an etiological agent that either directly or indirectly cause, not only NS, but also other forms of epilepsy in onchocerciasis endemic regions. ..
- Kateera F, Nsobya S, Tukwasibwe S, Mens P, Hakizimana E, Grobusch M, et al. Malaria case clinical profiles and Plasmodium falciparum parasite genetic diversity: a cross sectional survey at two sites of different malaria transmission intensities in Rwanda. Malar J. 2016;15:237 pubmed publisher..falciparum associated parameters such as drug resistance, immunity and impact of used interventions, and in proper interpretation of malaria vaccine studies. ..
- Stanaway J, Flaxman A, Naghavi M, Fitzmaurice C, Vos T, Abubakar I, et al. The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013. Lancet. 2016;388:1081-1088 pubmed publisher..The enormous health loss attributable to viral hepatitis, and the availability of effective vaccines and treatments, suggests an important opportunity to improve public health. Bill & Melinda Gates Foundation. ..
- Henriksson D, Ayebare F, Waiswa P, Peterson S, Tumushabe E, Fredriksson M. Enablers and barriers to evidence based planning in the district health system in Uganda; perceptions of district health managers. BMC Health Serv Res. 2017;17:103 pubmed publisher..Given the important role elected officials play in a decentralized system a concerted effort should be made to increase their knowledge on evidence-based planning and the district health system as a whole. ..
- Robinson H, Afako R, Wickenden M, Hartley S. Preliminary planning for training speech and language therapists in Uganda. Folia Phoniatr Logop. 2003;55:322-8 pubmed..The paper relates these issues to the International Association of Logopedics and Phoniatrics guidelines for education and training and makes suggestions for the way forward. ..
- Kabatereine N, Brooker S, Tukahebwa E, Kazibwe F, Onapa A. Epidemiology and geography of Schistosoma mansoni in Uganda: implications for planning control. Trop Med Int Health. 2004;9:372-80 pubmed..The results are discussed in reference to the ecology of infection and provide an epidemiological framework for the design and implementation of control efforts underway in Uganda. ..
- Nakubulwa S, Mirembe F, Kaye D, Kaddu Mulindwa D. Association between HSV-2 and HIV serostatus in pregnant women of known HIV serostatus attending Mulago hospital antenatal clinic, Kampala, Uganda. J Infect Dev Ctries. 2009;3:803-6 pubmed..The objective of this study was to compare the proportion of HSV-2 in HIV-positive and HIV-negative pregnant mothers attending the antenatal clinic in Mulago Teaching Hospital in Kampala, Uganda...
- Manabe Y, Wang Y, Elbireer A, Auerbach B, Castelnuovo B. Evaluation of portable point-of-care CD4 counter with high sensitivity for detecting patients eligible for antiretroviral therapy. PLoS ONE. 2012;7:e34319 pubmed publisher..The high sensitivity and negative predictive value of the test makes it an attractive option for field use to identify patients eligible for ART, thus potentially reducing delays in linkage to care and ART initiation. ..
- Olwit C, Musisi S, Leshabari S, Sanyu I. Chronic sorrow: lived experiences of caregivers of patients diagnosed with schizophrenia in Butabika Mental Hospital, Kampala, Uganda. Arch Psychiatr Nurs. 2015;29:43-8 pubmed publisher..The findings may enlighten psychiatric nurses in the care of mentally ill patients, caregivers and family members. The results may also help policy makers to prioritize mental health in the country. ..
- Mwesige G, Farah H, Koutsopoulos H. Risk appraisal of passing zones on two-lane rural highways and policy applications. Accid Anal Prev. 2016;90:1-12 pubmed publisher..Applications of the results for safety improvements of two-lane rural highways are also discussed. ..
- Chiwanga F, Njelekela M, Diamond M, Bajunirwe F, Guwatudde D, Nankya Mutyoba J, et al. Urban and rural prevalence of diabetes and pre-diabetes and risk factors associated with diabetes in Tanzania and Uganda. Glob Health Action. 2016;9:31440 pubmed publisher..These findings highlight the need for large-scale, prospective studies to accurately quantify the burden and identify effective intervention and treatment strategies across diverse African populations. ..
- Mafigiri R, Nsubuga F, Ario A. Risk factors for measles death: Kyegegwa District, western Uganda, February-September, 2015. BMC Infect Dis. 2017;17:462 pubmed publisher..The one-dose measles vaccination currently in the national vaccination schedule had a protective effect against measles death. We recommended enhancing measles vaccination and adherence to measles treatment guidelines. ..
- Ndawula J, Kabasa J, Byaruhanga Y. Alterations in fruit and vegetable beta-carotene and vitamin C content caused by open-sun drying, visqueen-covered and polyethylene-covered solar-dryers. Afr Health Sci. 2004;4:125-30 pubmed..The drying technologies should be improved to enhance vitamin retention. ..
- Nabyonga J, Desmet M, Karamagi H, Kadama P, Omaswa F, Walker O. Abolition of cost-sharing is pro-poor: evidence from Uganda. Health Policy Plan. 2005;20:100-8 pubmed..The study suggests that there is a financial barrier created by cost-sharing that decreases access to services, especially among the poor in Uganda. However, further studies are needed to clarify issues of utilization by age and gender. ..
- Tumwine J, Kekitiinwa A, Bakeera Kitaka S, Ndeezi G, Downing R, Feng X, et al. Cryptosporidiosis and microsporidiosis in ugandan children with persistent diarrhea with and without concurrent infection with the human immunodeficiency virus. Am J Trop Med Hyg. 2005;73:921-5 pubmed..Seventy-four percent of isolates were C. hominis, the anthroponotic species, 17% were C. parvum, the zoonotic species, and 8% were a mixture of the two or others. ..
- Mpimbaza A, Ndeezi G, Staedke S, Rosenthal P, Byarugaba J. Comparison of buccal midazolam with rectal diazepam in the treatment of prolonged seizures in Ugandan children: a randomized clinical trial. Pediatrics. 2008;121:e58-64 pubmed publisher..Buccal midazolam was as safe as and more effective than rectal diazepam for the treatment of seizures in Ugandan children, although benefits were limited to children without malaria. ..
- Asiimwe B, Ghebremichael S, Kallenius G, Koivula T, Joloba M. Mycobacterium tuberculosis spoligotypes and drug susceptibility pattern of isolates from tuberculosis patients in peri-urban Kampala, Uganda. BMC Infect Dis. 2008;8:101 pubmed publisher..The TB epidemic in Kampala is localized, mainly caused by the T2 family of strains. Strain types were neither associated with drug resistance nor HIV sero-status. ..
- Kiwanuka N, Laeyendecker O, Quinn T, Wawer M, Shepherd J, Robb M, et al. HIV-1 subtypes and differences in heterosexual HIV transmission among HIV-discordant couples in Rakai, Uganda. AIDS. 2009;23:2479-84 pubmed publisher..Differential subtype transmission efficiency may be important for HIV vaccine evaluation and could contribute to subtype-specific HIV epidemics in sub-Saharan Africa. ..
- Ndayambagye E, Nakalembe M, Kaye D. Factors associated with persistent hypertension after puerperium among women with pre-eclampsia/eclampsia in Mulago hospital, Uganda. BMC Pregnancy Childbirth. 2010;10:12 pubmed publisher..Serum creatinine, serum uric acid and participants' age were the only factors independently associated with persistence of hypertension after the puerperium. ..
- Tumwikirize W, Ogwal Okeng J, Vernby A, Anokbonggo W, Gustafsson L, Lundborg S. Adverse drug reactions in patients admitted on internal medicine wards in a district and regional hospital in Uganda. Afr Health Sci. 2011;11:72-8 pubmed..2 days vs 3.9 (p-value 0.129). ADRs are an important cause of morbidity in patients, both in the community and in hospitals, and the majority are associated with the commonly used drugs. ..
- Namisango E, Harding R, Atuhaire L, Ddungu H, Katabira E, Muwanika F, et al. Pain among ambulatory HIV/AIDS patients: multicenter study of prevalence, intensity, associated factors, and effect. J Pain. 2012;13:704-13 pubmed publisher..Pain is a common symptom among ambulatory HIV/AIDS patients and has a debilitating effect on QOL. There is a significant unmet need for pain relief in the population...
- Sewankambo N, Tumwine J, Tomson G, Obua C, Bwanga F, Waiswa P, et al. Enabling dynamic partnerships through joint degrees between low- and high-income countries for capacity development in global health research: experience from the Karolinska Institutet/Makerere University partnership. PLoS Med. 2015;12:e1001784 pubmed publisher
- Ononge S, Mirembe F, Wandabwa J, Campbell O. Incidence and risk factors for postpartum hemorrhage in Uganda. Reprod Health. 2016;13:38 pubmed publisher..The incidence of postpartum hemorrhage was high in our setting despite use of uterotonics. The risk factors identified could be addressed by extra vigilance during labour and preparedness for PPH management in all women giving birth. ..
- Loum D, Katholi C, Lakwo T, Habomugisha P, Tukahebwa E, Unnasch T. Evaluation of Community-Directed Operation of Black Fly Traps for Entomological Surveillance of Onchocerca volvulus Transmission in the Madi-Mid North Focus of Onchocerciasis in Northern Uganda. Am J Trop Med Hyg. 2017;97:1235-1242 pubmed publisher..The results suggest that EWTs may be effectively operated by community residents and that the trap represents a viable alternative to human landing collections for entomological surveillance of O. volvulus transmission...
- Idro R, Karamagi C, Tumwine J. Immediate outcome and prognostic factors for cerebral malaria among children admitted to Mulago Hospital, Uganda. Ann Trop Paediatr. 2004;24:17-24 pubmed..In primary health units, health workers may use a combination of cold peripheries, hypothermia and dehydration to predict circulatory failure...
- Mugisha F, Birungi H, Askew I. Are reproductive health NGOs in Uganda able to engage in the health SWAp?. Int J Health Plann Manage. 2005;20:227-38 pubmed
- Kirungi W, Musinguzi J, Madraa E, Mulumba N, Callejja T, Ghys P, et al. Trends in antenatal HIV prevalence in urban Uganda associated with uptake of preventive sexual behaviour. Sex Transm Infect. 2006;82 Suppl 1:i36-41 pubmed..The ecological correlation between the trends in HIV prevalence and incidence and the increase in protective sexual behaviour during the 1990s makes a compelling case for continuing prevention efforts in Uganda. ..
- Asio S, Simonsen P, Onapa A. A randomised, double-blind field trial of ivermectin alone and in combination with albendazole for the treatment of Mansonella perstans infections in Uganda. Trans R Soc Trop Med Hyg. 2009;103:274-9 pubmed publisher..ClinicalTrials.gov identifier: NCT00215280]...
- Beyeza Kashesya J, Ekstrom A, Kaharuza F, Mirembe F, Neema S, Kulane A. My partner wants a child: a cross-sectional study of the determinants of the desire for children among mutually disclosed sero-discordant couples receiving care in Uganda. BMC Public Health. 2010;10:247 pubmed publisher..Interventions targeting sero-discordant couples should explore contraceptive choices, the cultural importance of children, and partner communication. ..
- Enyaru J, Ouma J, Malele I, Matovu E, Masiga D. Landmarks in the evolution of technologies for identifying trypanosomes in tsetse flies. Trends Parasitol. 2010;26:388-94 pubmed publisher..Over this period, methods for detecting and identifying trypanosomes have evolved through various landmark discoveries. This review describes the evolution of methods for identifying African trypanosomes in their tsetse fly vectors. ..
- Amuha M, Kutyabami P, Kitutu F, Odoi Adome R, Kalyango J. Non-adherence to anti-TB drugs among TB/HIV co-infected patients in Mbarara Hospital Uganda: prevalence and associated factors. Afr Health Sci. 2009;9 Suppl 1:S8-15 pubmed..Patients that are on continuous phase of TB treatment should be supported to continue taking their drugs. In addition, patients that drink alcohol; smoke and those not on ART should be targeted with interventions to improve adherence. ..
- Nalwadda G, Mirembe F, Byamugisha J, Faxelid E. Persistent high fertility in Uganda: young people recount obstacles and enabling factors to use of contraceptives. BMC Public Health. 2010;10:530 pubmed publisher..Alternative models of contraceptive service delivery to young people are proposed. ..
- Nankabirwa V, Tylleskar T, Nankunda J, Engebretsen I, Sommerfelt H, Tumwine J. Malaria parasitaemia among infants and its association with breastfeeding peer counselling and vitamin A supplementation: a secondary analysis of a cluster randomized trial. PLoS ONE. 2011;6:e21862 pubmed publisher..Children that had not received Vitamin A supplementation had a higher prevalence of malaria compared to children that had been supplemented. Clinicaltrials.gov: NCT00397150. ..
- Ocama P, Seremba E. Management of HIV and hepatitis C virus infections in resource-limited settings. Curr Opin HIV AIDS. 2011;6:539-45 pubmed publisher..Treatment is difficult in some of the RLSs and prevention by screening donor blood as well and use of sterile instruments in treatment of patients will be important in curbing transmission in some of these settings. ..
- Aizire J, McConnell M, Mudiope P, Mubiru M, Matovu F, Parsons T, et al. Kinetics of nevirapine and its impact on HIV-1 RNA levels in maternal plasma and breast milk over time after perinatal single-dose nevirapine. J Acquir Immune Defic Syndr. 2012;60:483-8 pubmed publisher..A longer "tail" (>1 week) of potent postnatal antiretroviral drugs is warranted to minimize the observed VL rebound and potential for NVP resistance as a result of persistent NVP traces. ..
- Kyabayinze D, Asiimwe C, Nakanjako D, Nabakooza J, Bajabaite M, Strachan C, et al. Programme level implementation of malaria rapid diagnostic tests (RDTs) use: outcomes and cost of training health workers at lower level health care facilities in Uganda. BMC Public Health. 2012;12:291 pubmed publisher..Given the good peer training noted in this study, there is need to explore the cost-effectiveness of a cascade training model for large scale implementation of RDTs. ..
- Wanyenze R, Wagner G, Tumwesigye N, Nannyonga M, Wabwire Mangen F, Kamya M. Fertility and contraceptive decision-making and support for HIV infected individuals: client and provider experiences and perceptions at two HIV clinics in Uganda. BMC Public Health. 2013;13:98 pubmed publisher..This study explored decisions to have or not to have children and contraceptive preferences among PLHIV at two clinics in Uganda...
- Hopkins H, Gonzalez I, Polley S, Angutoko P, Ategeka J, Asiimwe C, et al. Highly sensitive detection of malaria parasitemia in a malaria-endemic setting: performance of a new loop-mediated isothermal amplification kit in a remote clinic in Uganda. J Infect Dis. 2013;208:645-52 pubmed publisher..A new commercial molecular assay based on loop-mediated isothermal amplification (LAMP) was assessed for field use...
- Okia M, Ndyomugyenyi R, Kirunda J, Byaruhanga A, Adibaku S, Lwamafa D, et al. Bioefficacy of long-lasting insecticidal nets against pyrethroid-resistant populations of Anopheles gambiae s.s. from different malaria transmission zones in Uganda. Parasit Vectors. 2013;6:130 pubmed publisher..With ongoing scale-up of insecticidal tools in the advent of increasing resistance, it is essential that those interventions with proven enhanced efficacy are given preference particularly in areas with high resistance. ..
- Semrau M, Evans Lacko S, Alem A, Ayuso Mateos J, Chisholm D, Gureje O, et al. Strengthening mental health systems in low- and middle-income countries: the Emerald programme. BMC Med. 2015;13:79 pubmed publisher..Emerald also addresses stigma and discrimination as one of the key barriers for access to and successful delivery of mental health services. ..
- Weiss H, Vandepitte J, Bukenya J, Mayanja Y, Nakubulwa S, Kamali A, et al. High Levels of Persistent Problem Drinking in Women at High Risk for HIV in Kampala, Uganda: A Prospective Cohort Study. Int J Environ Res Public Health. 2016;13:153 pubmed publisher..This longitudinal study found high levels of persistent problem drinking. Further research is needed to adapt and implement alcohol-focused interventions in vulnerable key populations in sub-Saharan Africa. ..
- Atugonza R, Kakooza Mwesige A, Lhatoo S, Kaddumukasa M, Mugenyi L, Sajatovic M, et al. Multiple anti-epileptic drug use in children with epilepsy in Mulago hospital, Uganda: a cross sectional study. BMC Pediatr. 2016;16:34 pubmed publisher..Multiple AED use is most frequent in symptomatic focal epilepsies but doses are frequently sub-optimal. There is urgent need to improve clinical monitoring in our patients. ..
- Nakalembe M, Mutyaba T, Mirembe F. Acceptability of study procedures (self-collected introital swabs, blood draws and stool sample collection) by students 10-16 years for an HPV vaccine effectiveness study: a pilot study. BMC Res Notes. 2016;9:170 pubmed publisher..The study procedures were highly acceptable among this study population of students and their parents. Follow-up to assess HPV vaccine effectiveness and factors that may influence the vaccine in this age group is feasible. ..
- Amanya G, Kizito S, Nabukenya I, Kalyango J, Atuheire C, Nansumba H, et al. Risk factors, person, place and time characteristics associated with Hepatitis E Virus outbreak in Napak District, Uganda. BMC Infect Dis. 2017;17:451 pubmed publisher..They also suggest that active surveillance and appropriate measures targeting community and routine individual health actions are important to prevent transmission and decrease the deaths. ..
- Katabarwa M, Habomugisha P, Agunyo S. Involvement and performance of women in community-directed treatment with ivermectin for onchocerciasis control in Rukungiri District, Uganda. Health Soc Care Community. 2002;10:382-93 pubmed..The present authors conclude that recruiting more female CDHWs and supervisors would reduce the current male domination of the health delivery services, greatly strengthening the activities of CDTI programmes. ..
- Ddungu H, Johnson J, Smieja M, Mayanja Kizza H. Digital clubbing in tuberculosis--relationship to HIV infection, extent of disease and hypoalbuminemia. BMC Infect Dis. 2006;6:45 pubmed..Clubbing occurs in up to one-third of Ugandan patients with pulmonary TB. Clubbing was not associated with stage of HIV infection, extensive disease or hypoalbuminemia. ..
- Bangirana P, Idro R, John C, Boivin M. Rehabilitation for cognitive impairments after cerebral malaria in African children: strategies and limitations. Trop Med Int Health. 2006;11:1341-9 pubmed..The limitations of implementing these interventions and solutions are discussed in light of the limited human resources and infrastructure of the developing countries that are malaria endemic. ..
- Oloya J, Opuda Asibo J, Kazwala R, Demelash A, Skjerve E, Lund A, et al. Mycobacteria causing human cervical lymphadenitis in pastoral communities in the Karamoja region of Uganda. Epidemiol Infect. 2008;136:636-43 pubmed..Isolation of environmental mycobacteria also confirms their increasing role in human disease and the occupational risk of infection in the transhumant ecosystem in the absence of safe drinking water and environmental contamination...
- Kolaczinski J, Kabatereine N, Onapa A, Ndyomugyenyi R, Kakembo A, Brooker S. Neglected tropical diseases in Uganda: the prospect and challenge of integrated control. Trends Parasitol. 2007;23:485-93 pubmed
- Castelnuovo B, Babigumira J, Lamorde M, Muwanga A, Kambugu A, Colebunders R. Improvement of the patient flow in a large urban clinic with high HIV seroprevalence in Kampala, Uganda. Int J STD AIDS. 2009;20:123-4 pubmed publisher..A similar methodology could be used by other health services to evaluate and compare different models of care. ..
- Ocama P, Katwere M, Piloya T, Feld J, Opio K, Kambugu A, et al. The spectrum of liver diseases in HIV infected individuals at an HIV treatment clinic in Kampala, Uganda. Afr Health Sci. 2008;8:8-12 pubmed..Drug history, liver enzyme studies, ultrasound, and hepatitis B and C investigations identified the probable etiology in 60 (78%) of 77 patients with HIV infection presenting with symptoms and/or signs of liver disease. ..
- Kiwanuka N, Robb M, Laeyendecker O, Kigozi G, Wabwire Mangen F, Makumbi F, et al. HIV-1 viral subtype differences in the rate of CD4+ T-cell decline among HIV seroincident antiretroviral naive persons in Rakai district, Uganda. J Acquir Immune Defic Syndr. 2010;54:180-4 pubmed publisher..Infection with subtype D is associated with significantly faster rates of CD4 T-cell loss than subtype A. This may explain the more rapid disease progression for subtype D compared with subtype A. ..
- Beyeza Kashesy J, Neema S, Ekstrom A, Kaharuza F, Mirembe F, Kulane A. "Not a boy, not a child": A qualitative study on young people's views on childbearing in Uganda. Afr J Reprod Health. 2010;14:71-81 pubmed
- Nalwadda G, Tumwesigye N, Faxelid E, Byamugisha J, Mirembe F. Quality of care in contraceptive services provided to young people in two Ugandan districts: a simulated client study. PLoS ONE. 2011;6:e27908 pubmed publisher..The quality of contraceptive services provided to young people was low. Concurrent quality improvements and strengthening of health systems are needed. ..
- Kalyango J, Hall M, Karamagi C. Home medication management practices and associated factors among patients with selected chronic diseases in a community pharmacy in Uganda. BMC Health Serv Res. 2012;12:323 pubmed publisher..In order to limit the occurrence of poor outcomes of treatment or drug toxicity, health providers need to strengthen the education of patients with chronic disease on how to handle their medicines at home. ..
- Nabyonga Orem J, Mugisha F, Okui A, Musango L, Kirigia J. Health care seeking patterns and determinants of out-of-pocket expenditure for malaria for the children under-five in Uganda. Malar J. 2013;12:175 pubmed publisher..This calls for provision of subsidies to enable the private sector to reduce prices, regulation of prices of malaria medicines, and reduction/removal of import duties on such medicines. ..
- Kisaalita W, Katimbo A, Sempiira E, Mugisa D. Cultural Influences in Women-Friendly Labor-Saving Hand Tool Designs: The Milk Churner Case. Hum Factors. 2016;58:27-42 pubmed publisher..The ultimate goal is to make the churner available to female smallholder dairy-farming households throughout Sub-Saharan Africa. This study provides a survival guide for generating solutions to problems from low-resource settings. ..
- Rempis E, Schnack A, Decker S, Braun V, Rubaihayo J, Tumwesigye N, et al. Option B+ for prevention of vertical HIV transmission has no influence on adverse birth outcomes in a cross-sectional cohort in Western Uganda. BMC Pregnancy Childbirth. 2017;17:82 pubmed publisher..Our results are encouraging with regard to continued universal scale-up of Option B+ and ART programmes. ..
- Abeku T, Helinski M, Kirby M, Ssekitooleko J, Bass C, Kyomuhangi I, et al. Insecticide resistance patterns in Uganda and the effect of indoor residual spraying with bendiocarb on kdr L1014S frequencies in Anopheles gambiae s.s. Malar J. 2017;16:156 pubmed publisher..This study suggests that using a carbamate insecticide for IRS in areas with high levels of pyrethroid resistance may reduce kdr frequencies in An. gambiae s.s. ..
- Feeser K, Cama V, Priest J, Thiele E, Wiegand R, Lakwo T, et al. Characterizing Reactivity to Onchocerca volvulus Antigens in Multiplex Bead Assays. Am J Trop Med Hyg. 2017;97:666-672 pubmed publisher..The OV-16 IgG4 assay would be useful for monitoring and evaluation using the MBA platform. Further evaluations are needed to review the potential use of OV-33 as a confirmatory test in the context of program evaluations. ..
- Ndyomugyenyi R, Minjas J. Urinary schistosomiasis in schoolchildren in Dar-es-Salaam, Tanzania, and the factors influencing its transmission. Ann Trop Med Parasitol. 2001;95:697-706 pubmed..Additional health education, to heighten awareness of the disease and its prevention, would also be beneficial. ..
- Kaye D, Mirembe F, Aziga F, Namulema B. Maternal mortality and associated near-misses among emergency intrapartum obstetric referrals in Mulago Hospital, Kampala, Uganda. East Afr Med J. 2003;80:144-9 pubmed..In developing countries, with poor obstetric services, emergency transfers in labour are very common. These women, who are of low status, contribute significantly to maternal mortality and morbidity. ..
- Meya D, McAdam K. The TB pandemic: an old problem seeking new solutions. J Intern Med. 2007;261:309-29 pubmed..The threat of drug resistance arising from ineffective TB treatment programmes is looming and could potentially lead to loss of any gains made in controlling the disease globally. ..
- Nsubuga M, Biggar R, Combs S, Marshall V, Mbisa G, Kambugu F, et al. Human herpesvirus 8 load and progression of AIDS-related Kaposi sarcoma lesions. Cancer Lett. 2008;263:182-8 pubmed publisher..We investigated these relationships in persons with AIDS...
- Lukande R, Wabinga H, Tumwine L. Burkitt's lymphoma in Uganda: the role of immunohistochemistry in diagnosis. East Afr Med J. 2008;85:207-12 pubmed..7% and 55.6%. Histology using haematoxylin and eosin staining is sensitive in the diagnosis of Burkitt's lymphoma but not very specific. Immunohistochemical staining with CD20, Ki-67 and bcl-2 is necessary for difficult cases. ..
- Hopkins H, Oyibo W, Luchavez J, Mationg M, Asiimwe C, Albertini A, et al. Blood transfer devices for malaria rapid diagnostic tests: evaluation of accuracy, safety and ease of use. Malar J. 2011;10:30 pubmed publisher..The inverted cup design achieved the highest overall performance, while the loop also performed well. These findings have relevance for any point-of-care diagnostics that require blood sampling. ..
- Namwanje H, Kabatereine N, Olsen A. A randomised controlled clinical trial on the safety of co-administration of albendazole, ivermectin and praziquantel in infected schoolchildren in Uganda. Trans R Soc Trop Med Hyg. 2011;105:181-8 pubmed publisher..The combined and conventional therapies were found to be equally safe. The efficacies of both therapies were comparable and satisfactory. [ClinicalTrials.gov identifier: NCT01050517]...
- Nanzigu S, Eriksen J, Makumbi F, Lanke S, Mahindi M, Kiguba R, et al. Pharmacokinetics of the nonnucleoside reverse transcriptase inhibitor efavirenz among HIV-infected Ugandans. HIV Med. 2012;13:193-201 pubmed publisher..Efavirenz CNS toxicity during the initial phase of treatment may be related to C(max) , regardless of the sampling time. ..
- Hermans S, Castelnuovo B, Katabira C, Mbidde P, Lange J, Hoepelman A, et al. Integration of HIV and TB services results in improved TB treatment outcomes and earlier prioritized ART initiation in a large urban HIV clinic in Uganda. J Acquir Immune Defic Syndr. 2012;60:e29-35 pubmed publisher..Integration of TB and HIV care has led to improved TB treatment outcomes and earlier, prioritized ART initiation. This supports rollout of a fully integrated TB/HIV service delivery model throughout high-prevalence TB and HIV settings. ..
- Neema S, Atuyambe L, Otolok Tanga E, Twijukye C, Kambugu A, Thayer L, et al. Using a clinic based creativity initiative to reduce HIV related stigma at the Infectious Diseases Institute, Mulago National Referral Hospital, Uganda. Afr Health Sci. 2012;12:231-9 pubmed publisher..Improved knowledge and communication are key in addressing self stigma among HIV positive individuals. ..
- Walusaga H, Kyohangirwe R, Wagner G. Gender differences in determinants of condom use among HIV clients in Uganda. AIDS Patient Care STDS. 2012;26:694-9 pubmed publisher..These data suggest the need for gender sensitive prevention programs and strategies, including programs that can provide women with greater control and self-efficacy regarding use of protective methods. ..
- Nakimuli A, Chazara O, Farrell L, Hiby S, Tukwasibwe S, Knee O, et al. Killer cell immunoglobulin-like receptor (KIR) genes and their HLA-C ligands in a Ugandan population. Immunogenetics. 2013;65:765-75 pubmed publisher..Our results will help understand how KIR/HLA-C interactions contribute to resistance to pathogens and reproductive success. ..
- Nantanda R, Ostergaard M, Ndeezi G, Tumwine J. Factors associated with asthma among under-fives in Mulago hospital, Kampala Uganda: a cross sectional study. BMC Pediatr. 2013;13:141 pubmed publisher..There is need for studies to explore the role of the above factors in development and exacerbation of childhood asthma to provide information that can be used to design strategies for asthma prevention and control. ..
- Wang H, Liddell C, Coates M, Mooney M, Levitz C, Schumacher A, et al. Global, regional, and national levels of neonatal, infant, and under-5 mortality during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384:957-79 pubmed publisher..Without further accelerated progress, many countries in west and central Africa will still have high levels of under-5 mortality in 2030. Bill & Melinda Gates Foundation, US Agency for International Development. ..
- Idro R, Opar B, Wamala J, Abbo C, Onzivua S, Mwaka D, et al. Is nodding syndrome an Onchocerca volvulus-induced neuroinflammatory disorder? Uganda's story of research in understanding the disease. Int J Infect Dis. 2016;45:112-7 pubmed publisher..Histological examination of post-mortem brains has shown some yet to be characterized polarizable material in the majority of specimens. Studies to confirm these observations and a clinical trial are planned for 2016. ..
- Mupere E, Zalwango S, Chiunda A, Okwera A, Mugerwa R, Whalen C. Body composition among HIV-seropositive and HIV-seronegative adult patients with pulmonary tuberculosis in Uganda. Ann Epidemiol. 2010;20:210-6 pubmed publisher..Gender, but not HIV status, was associated with body composition changes in TB. TB appears to be the dominant factor driving the wasting process among co-infected patients. ..
- Ndyomugyenyi R. The burden of onchocerciasis in Uganda. Ann Trop Med Parasitol. 1998;92 Suppl 1:S133-7 pubmed..It seems likely that it would be best to give Mectizan at intervals of < 1 year and that such frequent treatment only becomes feasible if Mectizan distribution is community-directed. ..
- Okong P, Biryahwaho B, Bergstrom S. Intrauterine infection after delivery: a marker of HIV-1 seropositivity among puerperal women in Uganda?. Int J STD AIDS. 2004;15:669-72 pubmed..In conclusion, PPEM cases had significantly higher seroprevalence of HIV-1 infection than controls and this needs further elucidation for purposes of management strategies. ..
- Orem J, Tindyebwa L, Twinoweitu O, Mukasa B, Tomberland M, Mbidde E. Feasibility study of serial lumbar puncture and acetazolamide combination in the management of elevated cerebrospinal fluid pressure in AIDS patients with cryptococcal meningitis in Uganda. Trop Doct. 2005;35:19-21 pubmed..This method is therefore feasible in AIDS-associated cryptococcal meningitis in a resource-poor setting given the observed safety and possible effectiveness, a larger study is warranted...
- Chamla D, Chamla J, Dabin W, Delin H, Rennes N. Transition to injection and sharing of needles/syringes: potential for HIV transmission among heroin users in Chengdu, China. Addict Behav. 2006;31:697-701 pubmed..Ethnic minorities have been identified to be the most risky group, which needs further attention. ..
- Obua C, Ntale M, Lundblad M, Mahindi M, Gustafsson L, Ogwal Okeng J, et al. Pharmacokinetic interactions between chloroquine, sulfadoxine and pyrimethamine and their bioequivalence in a generic fixed-dose combination in healthy volunteers in Uganda. Afr Health Sci. 2006;6:86-92 pubmed..Compared with GMP made drugs, both S and CQ are bioequivalent in Homapak, the Ugandan made fixed-dose formulation. Furthermore, the absorption of S was more rapid which could be advantageous in malaria treatment. ..
- Onapa A, Pedersen E, Reimert C, Simonsen P. A role for Mansonia uniformis mosquitoes in the transmission of lymphatic filariasis in Uganda?. Acta Trop. 2007;101:159-68 pubmed..uniformis. It is concluded that M. uniformis has a limited potential to support development of W. bancrofti to the infective stage, and it does not appear to play a role as a vector under natural conditions...
- Nalwoga H, Arnes J, Wabinga H, Akslen L. Frequency of the basal-like phenotype in African breast cancer. APMIS. 2007;115:1391-9 pubmed publisher..Our findings might be significant in relation to clinical management of these patients, including novel targeted therapy. ..
- Lewis R, Kisakye A, Gessner B, Duku C, Odipio J, Iriso R, et al. Action for child survival: elimination of Haemophilus influenzae type b meningitis in Uganda. Bull World Health Organ. 2008;86:292-301 pubmed..To guide immunization policy, we determined the public health benefit of introducing Haemophilus influenzae type b (Hib) vaccine in Uganda and estimated the vaccine effectiveness...