Experts and Doctors on hct116 cells in Tainan, Taiwan
Locale: Tainan, Taiwan
Topic: hct116 cells
Hsu L, Schultz L, Hong Q, Van Moer K, Heath J, Li M, et al
. Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1. J Biol Chem. 2009;284:16049-59 pubmed publisher
..Together, TGF-beta1 invokes a novel signaling by engaging cell surface Hyal-2 and recruiting WOX1 for regulating the activation of Smad-driven promoter, thereby controlling cell growth and death. ..
Feng Y, Tsao C, Wu C, Chang J, Lu P, Yeh K, et al
. Sprouty2 protein enhances the response to gefitinib through epidermal growth factor receptor in colon cancer cells. Cancer Sci. 2010;101:2033-8 pubmed publisher
Lai M, Chang C, Sun H. Hypoxia Induces Autophagy through Translational Up-Regulation of Lysosomal Proteins in Human Colon Cancer Cells. PLoS ONE. 2016;11:e0153627 pubmed publisher
..Our studies highlight the importance of translational regulation for tumor cell adaptation to hypoxia. ..
Hsiao K, Lin Y, Gupta S, Chang N, Yen L, Sun H, et al
. Noncoding Effects of Circular RNA CCDC66 Promote Colon Cancer Growth and Metastasis. Cancer Res. 2017;77:2339-2350 pubmed publisher
..Taken together, these findings highlight a novel oncogenic function of circRNA in cancer progression and metastasis. Cancer Res; 77(9); 2339-50. Â©2017 AACR. ..
Luo C, Wang J, Hung W, Peng G, Tsai Y, Chang T, et al
. G9a governs colon cancer stem cell phenotype and chemoradioresistance through PP2A-RPA axis-mediated DNA damage response. Radiother Oncol. 2017;124:395-402 pubmed publisher
..Our study theorized that G9a might serve as a novel target in colon cancer, which offers exciting potential in prediction of response to preoperative chemoradiotherapy in patients with advanced CRC. ..
Hou P, Li Y, Lin S, Lin S, Lee J, Lin B, et al
. Hypoxia-Induced Downregulation of DUSP-2 Phosphatase Drives Colon Cancer Stemness. Cancer Res. 2017;77:4305-4316 pubmed publisher
..Our findings illuminate mechanisms of cancer stemness and suggest new cancer therapy regimens. Cancer Res; 77(16); 4305-16. Â©2017 AACR. ..
Feng Y, Wu C, Tsao C, Chang J, Lu P, Yeh K, et al
. Deregulated expression of sprouty2 and microRNA-21 in human colon cancer: Correlation with the clinical stage of the disease. Cancer Biol Ther. 2011;11:111-21 pubmed
..Thus, Spry2 functions as a tumor suppressor in colon cancer. ..