Experts and Doctors on mitochondrial proteins in Lausanne, Vaud, Switzerland
Locale: Lausanne, Vaud, Switzerland
Topic: mitochondrial proteins
Stutz F, Bachi A, Doerks T, Braun I, Seraphin B, Wilm M, et al
. REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export. RNA. 2000;6:638-50 pubmed
..Thus, Yra1p and members of the REF family of hnRNP-like proteins may facilitate the interaction of TAP/Mex67p with cellular mRNAs. ..
Colombo S, Soranzo N, Rotger M, Sprenger R, Bleiber G, Furrer H, et al
. Influence of ABCB1, ABCC1, ABCC2, and ABCG2 haplotypes on the cellular exposure of nelfinavir in vivo. Pharmacogenet Genomics. 2005;15:599-608 pubmed
..Genetic polymorphism in these genes may be associated with changes in transport function...
Mounien L, Marty N, Tarussio D, Metref S, Genoux D, Preitner F, et al
. Glut2-dependent glucose-sensing controls thermoregulation by enhancing the leptin sensitivity of NPY and POMC neurons. FASEB J. 2010;24:1747-58 pubmed publisher
..Thus, our data suggest that glucose controls thermoregulation and the leptin sensitivity of NPY and POMC neurons through activation of Glut2-dependent glucose-sensing neurons located outside of the arcuate nucleus. ..
Zaltsman Y, Shachnai L, Yivgi Ohana N, Schwarz M, Maryanovich M, Houtkooper R, et al
. MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria. Nat Cell Biol. 2010;12:553-562 pubmed publisher
..These loss-of-function models indicate that MTCH2/MIMP has a critical function in liver apoptosis by regulating the recruitment of tBID to mitochondria. ..
Fernandez Marcos P, Jeninga E, Canto C, Harach T, de Boer V, Andreux P, et al
. Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis. Sci Rep. 2012;2:425 pubmed publisher
Barde I, Rauwel B, Marin Florez R, Corsinotti A, Laurenti E, Verp S, et al
. A KRAB/KAP1-miRNA cascade regulates erythropoiesis through stage-specific control of mitophagy. Science. 2013;340:350-3 pubmed publisher
..Thus, a multilayered transcription regulatory system is present, in which protein- and RNA-based repressors are superimposed in combinatorial fashion to govern the timely triggering of an important differentiation event. ..
QuirÃ³s P, Prado M, Zamboni N, D Amico D, Williams R, Finley D, et al
. Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals. J Cell Biol. 2017;216:2027-2045 pubmed publisher
..Our data illustrate the value of a multiomics approach to characterize complex cellular networks and provide a versatile resource to identify new regulators of mitochondrial-related diseases. ..
Glauser L, Sonnay S, Stafa K, Moore D. Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1. J Neurochem. 2011;118:636-45 pubmed publisher
..This process may serve to selectively isolate damaged mitochondria for their removal by autophagy. ..
Quirós P, Mottis A, Auwerx J. Mitonuclear communication in homeostasis and stress. Nat Rev Mol Cell Biol. 2016;17:213-26 pubmed publisher
..We discuss how mitonuclear communication safeguards cellular and organismal fitness and regulates lifespan. ..