Experts and Doctors on immunohistochemistry in Madrid, Spain


Locale: Madrid, Spain
Topic: immunohistochemistry

Top Publications

  1. Santos Briz A, Antúnez P, Lopez Rios F, Rodriguez Peralto J, Garzon A. Human papillomavirus-negative spindle cell carcinoma of the vulva associated with lichen sclerosus: case report and literature review. Am J Dermatopathol. 2002;24:135-8 pubmed
    ..HPV testing by polymerase chain reaction was negative. In addition, we review the clinicopathologic findings of the four well-documented cases of vulvar SC that have been reported previously in the English language literature. ..
  2. Cassia R, Moreno Bueno G, Rodriguez Perales S, Hardisson D, Cigudosa J, Palacios J. Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma. J Pathol. 2003;201:589-95 pubmed
    ..Although hCDC4 exhibits a low mutation frequency in ECs overexpressing cyclin E, it seems to function as a tumour suppressor gene that is involved in endometrial carcinogenesis. ..
  3. Sarrio D, Perez Mies B, Hardisson D, Moreno Bueno G, Suárez A, Cano A, et al. Cytoplasmic localization of p120ctn and E-cadherin loss characterize lobular breast carcinoma from preinvasive to metastatic lesions. Oncogene. 2004;23:3272-83 pubmed
    ..Consequently, p120 may be an important mediator of the oncogenic effects derived from E-CD inactivation, including enhanced motility and invasion, in lobular breast cancer. ..
  4. García Berrocal J, Ramírez Camacho R, Trinidad A, Zurita M, de la Fuente R, Lobo D. Controversies and criticisms on designs for experimental autoimmune labyrinthitis. Ann Otol Rhinol Laryngol. 2004;113:404-10 pubmed
    ..A new pathogenetic theory is suggested, involving the supporting cells of the organ of Corti...
  5. Hervás C, Pérez Sen R, Miras Portugal M. Presence of diverse functional P2X receptors in rat cerebellar synaptic terminals. Biochem Pharmacol. 2005;70:770-85 pubmed
    ..This study reports the presence of functional P2X3 and P2X7 receptors at synaptic sites, which provides complexity and regulatory possibilities to the cerebellar neurotransmission. ..
  6. Avendano C, de Las Heras S, Giménez Amaya J. Striatal projections from the lateral and posterior thalamic complexes. An anterograde tracer study in the cat. Histochem Cell Biol. 2006;125:265-71 pubmed
    ..The former coincided with the acetylcholinesterase-poor striosomes and the latter areas of dense projection with the extrastriosomal matrix. ..
  7. Clemente M, Nunez O, Lorente R, Rincon D, Matilla A, Salcedo M, et al. Increased intrahepatic and circulating levels of endoglin, a TGF-beta1 co-receptor, in patients with chronic hepatitis C virus infection: relationship to histological and serum markers of hepatic fibrosis. J Viral Hepat. 2006;13:625-32 pubmed
    ..These data suggest an active role for endoglin in the fibrotic process featuring chronic HCV infection. ..
  8. Inda M, Defelipe J, Munoz A. The distribution of chandelier cell axon terminals that express the GABA plasma membrane transporter GAT-1 in the human neocortex. Cereb Cortex. 2007;17:2060-71 pubmed
    ..These differences might be related to the different functional attributes of the cortical regions examined. ..
  9. Morona R, González A. Immunohistochemical localization of calbindin-D28k and calretinin in the brainstem of anuran and urodele amphibians. J Comp Neurol. 2009;515:503-37 pubmed publisher
    ..These results highlight the anatomical complexity of the amphibian brainstem and help in an understanding of its regional organization that is not cytoarchitectonically evident. ..

More Information

Publications209 found, 100 shown here

  1. Cruz C, Glavic A, Casado M, de Celis J. A gain-of-function screen identifying genes required for growth and pattern formation of the Drosophila melanogaster wing. Genetics. 2009;183:1005-26 pubmed publisher
    ..Finally, we present a preliminary characterization of a gene identified in the screen, the function of which is required for the development of the L5 longitudinal vein. ..
  2. Lopez J, Dominguez L, Moreno N, Morona R, Joven A, González A. Distribution of orexin/hypocretin immunoreactivity in the brain of the lungfishes Protopterus dolloi and Neoceratodus forsteri. Brain Behav Evol. 2009;74:302-22 pubmed publisher
  3. Morel E, Escamochero S, Cabañas R, Diaz R, Fiandor A, Bellón T. CD94/NKG2C is a killer effector molecule in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis. J Allergy Clin Immunol. 2010;125:703-10, 710.e1-710.e8 pubmed publisher
    ..CD94/NKG2C might be involved in triggering cytotoxic lymphocytes in patients with SJS and TEN. ..
  4. Sanchez Mendoza E, Burguete M, Castelló Ruiz M, González M, Roncero C, Salom J, et al. Transient focal cerebral ischemia significantly alters not only EAATs but also VGLUTs expression in rats: relevance of changes in reactive astroglia. J Neurochem. 2010;113:1343-55 pubmed publisher
  5. Aguilar Morante D, Morales Garcia J, Sanz Sancristobal M, Garcia Cabezas M, Santos A, Perez Castillo A. Inhibition of glioblastoma growth by the thiadiazolidinone compound TDZD-8. PLoS ONE. 2010;5:e13879 pubmed publisher
    ..Our results suggest that TDZD-8 uses a novel mechanism to target glioblastoma cells, and that malignant progenitor population could be a target of this compound. ..
  6. Jordán Álvarez S, Fouquet W, Sigrist S, Acebes A. Presynaptic PI3K activity triggers the formation of glutamate receptors at neuromuscular terminals of Drosophila. J Cell Sci. 2012;125:3621-9 pubmed
    ..Taken together, these results demonstrate that PI3K-dependent synaptogenesis plays an instructive role in PSD formation and growth from the presynaptic side. ..
  7. Georgiev Hristov T, Garcia Arranz M, García Gómez I, Garcia Cabezas M, Trebol J, Vega Clemente L, et al. Sutures enriched with adipose-derived stem cells decrease the local acute inflammation after tracheal anastomosis in a murine model. Eur J Cardiothorac Surg. 2012;42:e40-7 pubmed publisher
    ..ASCs suppress the local acute inflammatory reaction (increased macrophage migration and decreased neutrophil infiltration) in the tracheal anastomosis and cause an early switch from acute to chronic inflammation. ..
  8. de Juan Sanz J, Núñez E, López Corcuera B, Aragón C. Constitutive endocytosis and turnover of the neuronal glycine transporter GlyT2 is dependent on ubiquitination of a C-terminal lysine cluster. PLoS ONE. 2013;8:e58863 pubmed publisher
  9. Llamas Velasco M, Pérez González Y, Requena L, Kutzner H. Histopathologic clues for the diagnosis of Wiesner nevus. J Am Acad Dermatol. 2014;70:549-54 pubmed publisher
    ..Immunohistochemically, Wiesner nevus is BAP1 negative and VE1 positive. ..
  10. Bartolomé M, Ibáñez Olías M, Gil Loyzaga P. Transitional expression of OX-2 and GAP-43 glycoproteins in developing rat cochlear nerve fibers. Histol Histopathol. 2002;17:83-95 pubmed publisher
    ..While both glycoproteins could participate in axonal growing and orientation, OX-2 could also be involved in a similar process for auditory dendrites. ..
  11. Palacios J, Honrado E, Osorio A, Cazorla A, Sarrio D, Barroso A, et al. Immunohistochemical characteristics defined by tissue microarray of hereditary breast cancer not attributable to BRCA1 or BRCA2 mutations: differences from breast carcinomas arising in BRCA1 and BRCA2 mutation carriers. Clin Cancer Res. 2003;9:3606-14 pubmed
    ..In addition, the study also demonstrates the usefulness of tissue microarray technology in the evaluation of the immunophenotypic features of hereditary breast cancer. ..
  12. Esteban V, Lorenzo O, Ruperez M, Suzuki Y, Mezzano S, Blanco J, et al. Angiotensin II, via AT1 and AT2 receptors and NF-kappaB pathway, regulates the inflammatory response in unilateral ureteral obstruction. J Am Soc Nephrol. 2004;15:1514-29 pubmed
  13. Arriazu R, Pozuelo J, Martin R, Rodriguez R, Santamaria L. Quantitative and immunohistochemical evaluation of PCNA, androgen receptors, apoptosis, and Glutathione-S-Transferase P1 on preneoplastic changes induced by cadmium and zinc chloride in the rat ventral prostate. Prostate. 2005;63:347-57 pubmed
    ..2) The decrease of apoptosis has little influence in the development of dysplasia. (3) GSTP1 could play a role in the response to the oxidative stress in the dysplastic changes caused by cadmium. ..
  14. Garcia Palencia P, Sanchez M, Nieto A, Vilar M, Gonzalez M, Veiga Lopez A, et al. Sex steroid receptor expression in the oviduct and uterus of sheep with estrus synchronized with progestagen or prostaglandin analogues. Anim Reprod Sci. 2007;97:25-35 pubmed
    ..05) on day 4 in the animals treated with progestagens. Results indicate that sheep with synchronization of estrus with progestagens showed a reduction of ERalpha and PR protein expression in most of oviductal and uterine cells. ..
  15. Munoz A, Mendez P, DeFelipe J, Alvarez Leefmans F. Cation-chloride cotransporters and GABA-ergic innervation in the human epileptic hippocampus. Epilepsia. 2007;48:663-73 pubmed
  16. Barreto G, Veiga S, Azcoitia I, Garcia Segura L, Garcia Ovejero D. Testosterone decreases reactive astroglia and reactive microglia after brain injury in male rats: role of its metabolites, oestradiol and dihydrotestosterone. Eur J Neurosci. 2007;25:3039-46 pubmed
    ..The regulation of gliosis may be part of the neuroprotective mechanism of testosterone. ..
  17. Sarrio D, Rodriguez Pinilla S, Hardisson D, Cano A, Moreno Bueno G, Palacios J. Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype. Cancer Res. 2008;68:989-97 pubmed publisher
  18. Martin M, Rodriguez Lescure A, Ruiz A, Alba E, Calvo L, Ruiz Borrego M, et al. Randomized phase 3 trial of fluorouracil, epirubicin, and cyclophosphamide alone or followed by Paclitaxel for early breast cancer. J Natl Cancer Inst. 2008;100:805-14 pubmed publisher
    ..Among patients with operable breast cancer, FEC-P treatment statistically significantly reduced the risk of relapse compared with FEC as adjuvant therapy. ..
  19. Morona R, González A. Calbindin-D28k and calretinin expression in the forebrain of anuran and urodele amphibians: further support for newly identified subdivisions. J Comp Neurol. 2008;511:187-220 pubmed publisher
    ..Therefore, the content of a particular calcium binding protein in a neuronal group is not a fully reliable criterion for considering homologies...
  20. Vandermeeren A, Gómez C, Patiño C, Domingo Gil E, Guerra S, Gonzalez J, et al. Subcellular forms and biochemical events triggered in human cells by HCV polyprotein expression from a viral vector. Virol J. 2008;5:102 pubmed publisher
    ..Our findings demonstrate the uniqueness of the VT7-HCV7.9 system to characterize morphological and biochemical events related to HCV pathogenesis. ..
  21. Largo R, Martinez Calatrava M, Sanchez Pernaute O, Marcos M, Moreno Rubio J, Aparicio C, et al. Effect of a high dose of glucosamine on systemic and tissue inflammation in an experimental model of atherosclerosis aggravated by chronic arthritis. Am J Physiol Heart Circ Physiol. 2009;297:H268-76 pubmed publisher
    ..GS also prevented the development of inflammation-associated aortic lesions. These results suggest an atheroprotective effect of GS. ..
  22. Jimenez Heffernan J, Corbacho C, Cañizal J, Pérez Campos A, Vicandi B, Lopez Ibor L, et al. Cytological changes induced by embolization in meningiomas. Cytopathology. 2012;23:57-60 pubmed publisher
    ..When faced with such changes the pathologist should consider the possibility of embolization, avoiding misdiagnosis of higher grade meningioma or metastatic carcinoma. ..
  23. Granado N, Ares Santos S, Oliva I, O Shea E, Martin E, Colado M, et al. Dopamine D2-receptor knockout mice are protected against dopaminergic neurotoxicity induced by methamphetamine or MDMA. Neurobiol Dis. 2011;42:391-403 pubmed publisher
    ..Our results demonstrate that the D2R is necessary for METH and MDMA neurotoxicity and that the neuroprotective effect of D2R inactivation is independent of its effect on body temperature. ..
  24. Gámez Pozo A, Sánchez Navarro I, Calvo E, Agulló Ortuño M, Lopez Vacas R, Diaz E, et al. PTRF/cavin-1 and MIF proteins are identified as non-small cell lung cancer biomarkers by label-free proteomics. PLoS ONE. 2012;7:e33752 pubmed publisher
    ..The application of discovery-based proteomics analyses in clinical samples allowed us to identify new potential biomarkers and therapeutic targets in non-small cell lung cancer. ..
  25. Martínez M, Ubeda A, Cid M, Trillo M. The proliferative response of NB69 human neuroblastoma cells to a 50 Hz magnetic field is mediated by ERK1/2 signaling. Cell Physiol Biochem. 2012;29:675-86 pubmed publisher
    ..Taken together, the described results indicate that a 50 Hz, 100 μT MF can stimulate proliferation in NB69 cells by triggering MAPK-ERK1/ 2 signaling at each of the "On" periods of an intermittent exposure. ..
  26. Revelles J, Machan S, Pielasinski U, Camacho D, Vallés L, Santonja C, et al. Pseudoxanthoma elasticum-like papillary dermal elastolysis: immunohistochemical study using elastic fiber cross-reactivity with an antibody against amyloid P component. Am J Dermatopathol. 2012;34:637-43 pubmed publisher
    ..We also review the literature about this rare process and discuss the differential diagnosis with other elastic tissue disorders that may show similar clinical and/or histopathologic findings...
  27. Benito Martin A, Ucero A, Izquierdo M, Santamaria B, Picatoste B, Carrasco S, et al. Endogenous NAMPT dampens chemokine expression and apoptotic responses in stressed tubular cells. Biochim Biophys Acta. 2014;1842:293-303 pubmed publisher
    ..Thus, disruption of endogenous NAMPT function in stressed cells promotes tubular cell death and chemokine expression. This information may be relevant for the design of novel therapeutic strategies in DN. ..
  28. Marazuela M, Acevedo A, García López M, Adrados M, de Marco M, Alonso M. Expression of MAL2, an integral protein component of the machinery for basolateral-to-apical transcytosis, in human epithelia. J Histochem Cytochem. 2004;52:243-52 pubmed
    ..Our results allow the prediction of the existence of MAL2-based trafficking pathways in specific cell types and suggest applications of the anti-MAL2 antibody for the characterization of neoplastic tissue. ..
  29. Venero C, Guadaño Ferraz A, Herrero A, Nordstrom K, Manzano J, de Escobar G, et al. Anxiety, memory impairment, and locomotor dysfunction caused by a mutant thyroid hormone receptor alpha1 can be ameliorated by T3 treatment. Genes Dev. 2005;19:2152-63 pubmed
    ..Here, the hormone treatment normalized the otherwise delayed cerebellar development. The data thus identify two novel and distinct functions of an unliganded TRalpha1 during development and adulthood, respectively. ..
  30. Rodríguez Casado A, Alvarez I, Toledano A, De Miguel E, Carmona P. Amphetamine effects on brain protein structure and oxidative stress as revealed by FTIR microspectroscopy. Biopolymers. 2007;86:437-46 pubmed
    ..These result suggest that ROS generated by amphetamine-mediated oxidative stress induce formation beta-sheet-rich proteins which can be of amyloid beta-like character. ..
  31. Nus M, MacGrogan D, Martínez Poveda B, Benito Y, Casanova J, Fernandez Aviles F, et al. Diet-induced aortic valve disease in mice haploinsufficient for the Notch pathway effector RBPJK/CSL. Arterioscler Thromb Vasc Biol. 2011;31:1580-8 pubmed publisher
    ..Our data establish a genetic mouse model of calcific aortic valve disease and may help to identify a patient population with reduced valvular NOTCH signaling at risk for developing this disease. ..
  32. Martin P, Salas C, Provencio M, Abraira V, Bellas C. Heterogeneous expression of Src tyrosine kinases Lyn, Fyn and Syk in classical Hodgkin lymphoma: prognostic implications. Leuk Lymphoma. 2011;52:2162-8 pubmed publisher
    ..05). Overexpression of Syk and the availability of Syk inhibitors suggest that this molecule might be a therapeutic strategy worthy of development for cases expressing this molecule. ..
  33. Muñoz Repeto I, Garcia M, Kamieniak M, Ramon Y Cajal T, Domingo S, Cazorla A, et al. Phenotypic characterization of hereditary epithelial ovarian cancer based on a tissue microarray study. Histol Histopathol. 2013;28:133-44 pubmed publisher
    ..Unsupervised cluster analysis and survival analysis identified ERCC1 as a potential marker of better clinical outcome for hereditary epithelial ovarian cancer. ..
  34. Barabási B, Csondor A, Martín Pozas T, Pulupa Sánchez A, Antalffy G, Siklós L, et al. Effect of axotomy and 17β-estradiol on P2X7 receptor expression pattern in the hypoglossal nucleus of ovariectomized mice. Neuroscience. 2016;319:107-15 pubmed publisher
    ..Our results suggest that axotomy induces cell-type specific changes in P2X7 receptor expression, which may be directly regulated by 17β-estradiol through ER alpha or beta in neurons, but not in activated microglia. ..
  35. del Rio M, Defelipe J. A study of SMI 32-stained pyramidal cells, parvalbumin-immunoreactive chandelier cells, and presumptive thalamocortical axons in the human temporal neocortex. J Comp Neurol. 1994;342:389-408 pubmed
  36. Jimenez M, Petit T, Gancedo C, Goday C. The alm1+ gene from Schizosaccharomyces pombe encodes a coiled-coil protein that associates with the medial region during mitosis. Mol Gen Genet. 2000;262:921-30 pubmed
    ..We propose that Alm1 participates in the structural organization of the medial region in S. pombe. ..
  37. Martinez Rodriguez R, Toledano A, Alvarez M, Turégano L, Colman O, Rosés P, et al. Chronic nicotine administration increases NGF-like immunoreactivity in frontoparietal cerebral cortex. J Neurosci Res. 2003;73:708-16 pubmed
    ..Nicotinic activation of selected neurons and glial cells seems to trigger NGF/neurotrophic mechanisms, suggesting their use may be of benefit in prevention and treatment of neurodegenerative diseases. ..
  38. Marazuela M, Martin Belmonte F, García López M, Aranda J, de Marco M, Alonso M. Expression and distribution of MAL2, an essential element of the machinery for basolateral-to-apical transcytosis, in human thyroid epithelial cells. Endocrinology. 2004;145:1011-6 pubmed
  39. Brun A, Castilla J, Ramirez M, Prager K, Parra B, Salguero F, et al. Proteinase K enhanced immunoreactivity of the prion protein-specific monoclonal antibody 2A11. Neurosci Res. 2004;48:75-83 pubmed
    ..Since definitive diagnosis of prion diseases rely on IHC assays of proteinase K-treated samples, the use of mAb 2A11 might contribute to reduce the occurrence of false positive detection due to incomplete proteinase K digestion. ..
  40. Lopez J, Moreno N, Morona R, González A. Distribution of neuropeptide FF-like immunoreactivity in the brain of Dermophis mexicanus (Amphibia; Gymnophiona): comparison with FMRFamide immunoreactivity. Brain Behav Evol. 2006;67:150-64 pubmed
  41. Suarez I, Bodega G, Arilla E, Felipo V, Fernandez B. The expression of nNOS, iNOS and nitrotyrosine is increased in the rat cerebral cortex in experimental hepatic encephalopathy. Neuropathol Appl Neurobiol. 2006;32:594-604 pubmed
  42. Arroba A, Lechuga Sancho A, Frago L, Argente J, Chowen J. Cell-specific expression of X-linked inhibitor of apoptosis in the anterior pituitary of streptozotocin-induced diabetic rats. J Endocrinol. 2007;192:215-27 pubmed
    ..Furthermore, both pituitary cell death and expression of protective mechanisms such as XIAP are cell-type specific. ..
  43. Aggarwal M, Villuendas R, Gomez G, Rodriguez Pinilla S, Sanchez Beato M, Alvarez D, et al. TCL1A expression delineates biological and clinical variability in B-cell lymphoma. Mod Pathol. 2009;22:206-15 pubmed publisher
  44. Crooke A, Mediero A, Guzm n Ar nguez A, Pintor J. Silencing of P2Y2 receptor delays Ap4A-corneal re-epithelialization process. Mol Vis. 2009;15:1169-78 pubmed
    ..The application of P2Y(2)-R siRNA has demonstrated the role of this receptor in the accelerating effect of diadenosine tetraphosphate (Ap(4)A) on the corneal wound healing process...
  45. Estacio Gómez A, Moris Sanz M, Schäfer A, Perea D, Herrero P, Diaz Benjumea F. Bithorax-complex genes sculpt the pattern of leucokinergic neurons in the Drosophila central nervous system. Development. 2013;140:2139-48 pubmed publisher
    ..We show that genes of the Bx-C acted in postmitotic cells to specify the segment-specific appearance of leucokinergic cells in the larval and adult ventral nerve cord. ..
  46. Millán C, Lujan R, Shigemoto R, Sánchez Prieto J. Subtype-specific expression of group III metabotropic glutamate receptors and Ca2+ channels in single nerve terminals. J Biol Chem. 2002;277:47796-803 pubmed
    ..This specific coexpression of different group III mGluRs and Ca(2+) channels may endow synaptic terminals with distinct release properties and reveals the existence of a high degree of presynaptic heterogeneity. ..
  47. Salamanca J, Rodriguez Peralto J, Azorin D, Ballestin C, de Agustin P. Paratesticular congenital malignant rhabdoid tumor diagnosed by fine-needle aspiration cytology. a case report. Diagn Cytopathol. 2004;30:46-50 pubmed
    ..We emphasize the characteristic cytologic features of a congenital rhabdoid tumor, which must be known by pathologists because of the clinical and prognostic implications. Diagn. Cytopathol. 2004;30:46-50. ..
  48. García Tuñón I, Ricote M, Ruiz A, Fraile B, Paniagua R, Royuela M. Cell cycle control related proteins (p53, p21, and Rb) and transforming growth factor beta (TGFbeta) in benign and carcinomatous (in situ and infiltrating) human breast: implications in malignant transformations. Cancer Invest. 2006;24:119-25 pubmed
    ..In the infiltrating tumors, the expression of p21 in the nuclei and the decrease in pRb expression suggest an insufficient attempt to hinder cell proliferation. ..
  49. Morona R, Lopez J, González A. Calbindin-D28k and calretinin immunoreactivity in the spinal cord of the lizard Gekko gecko: Colocalization with choline acetyltransferase and nitric oxide synthase. Brain Res Bull. 2006;69:519-34 pubmed
  50. Morona R, Lopez J, Dominguez L, González A. Immunohistochemical and hodological characterization of calbindin-D28k-containing neurons in the spinal cord of the turtle, Pseudemys scripta elegans. Microsc Res Tech. 2007;70:101-18 pubmed
  51. Jiménez A, Sanchez B, Pérez Alenza D, Garcia P, López J, Rodriguez A, et al. Membranous glomerulonephritis in the Iberian lynx (Lynx pardinus). Vet Immunol Immunopathol. 2008;121:34-43 pubmed
    ..We postulate a possible genetic predisposition towards the disease, enhanced by inbreeding and a possible connection to an immune-mediated systemic disease...
  52. Marin Garcia P, Sánchez Nogueiro J, Gomez Villafuertes R, Leon D, Miras Portugal M. Synaptic terminals from mice midbrain exhibit functional P2X7 receptor. Neuroscience. 2008;151:361-73 pubmed
    ..These biochemical and pharmacological experiments are consistent with the presence of a functional P2X(7) receptor in wild type mice midbrain, and the existence of a less efficient "P2X(7)-like" receptor in the KO model. ..
  53. Lorz C, Benito Martin A, Boucherot A, Ucero A, Rastaldi M, Henger A, et al. The death ligand TRAIL in diabetic nephropathy. J Am Soc Nephrol. 2008;19:904-14 pubmed publisher
    ..TRAIL also activated NF-kappaB, and inhibition of NF-kappaB sensitized cells to TRAIL-induced apoptosis. It is proposed that TRAIL-induced cell death could play an important role in the progression of human DN. ..
  54. Sanchez Nino M, Sanz A, Ihalmo P, Lassila M, Holthofer H, Mezzano S, et al. The MIF receptor CD74 in diabetic podocyte injury. J Am Soc Nephrol. 2009;20:353-62 pubmed publisher
    ..These data suggest that CD74 acts as a receptor for MIF in podocytes and may play a role in the pathogenesis of diabetic nephropathy. ..
  55. Galindo M, Gonzalo E, Martinez Vidal M, Montes S, Redondo N, Santiago B, et al. Immunohistochemical detection of intravascular platelet microthrombi in patients with lupus nephritis and anti-phospholipid antibodies. Rheumatology (Oxford). 2009;48:1003-7 pubmed publisher
    ..In contrast, histological lesions consistent with APS nephropathy were not associated with aPLs but with cardiovascular risk factors and worse renal outcome. ..
  56. Fernández Lamo I, Montero Pedrazuela A, Delgado García J, Guadaño Ferraz A, Gruart A. Effects of thyroid hormone replacement on associative learning and hippocampal synaptic plasticity in adult hypothyroid rats. Eur J Neurosci. 2009;30:679-92 pubmed publisher
    ..The present results have important clinical implications for the handling of patients with adult-onset thyroid diseases. ..
  57. Romero A, Martin M, Cheang M, López García Asenjo J, Oliva B, He X, et al. Assessment of Topoisomerase II ? status in breast cancer by quantitative PCR, gene expression microarrays, immunohistochemistry, and fluorescence in situ hybridization. Am J Pathol. 2011;178:1453-60 pubmed publisher
    ..All of these features should be taken into consideration when assessing the predictive value of TOP2A for anthracycline-based chemotherapy. ..
  58. Molina Ruiz A, Del Carmen Fariña M, Carrasco L, Santonja C, Rodriguez Peralto J, Torrelo A, et al. Saurian papulosis: a new clinicopathological entity. J Am Acad Dermatol. 2013;68:e17-22 pubmed publisher
    ..Only two patients and one sibling were investigated. We propose the name "saurian papulosis" to describe this newly described clinicopathologic entity. ..
  59. Peralta S, Clemente P, Sanchez Martinez A, Calleja M, Hernández Sierra R, Matsushima Y, et al. Coiled coil domain-containing protein 56 (CCDC56) is a novel mitochondrial protein essential for cytochrome c oxidase function. J Biol Chem. 2012;287:24174-85 pubmed publisher
    ..melanogaster. We propose CCDC56 as a candidate factor required for COX biogenesis/assembly. ..
  60. Simon Areces J, Acaz Fonseca E, Ruiz Palmero I, Garcia Segura L, Arevalo M. A CRM1-mediated nuclear export signal is essential for cytoplasmic localization of neurogenin 3 in neurons. PLoS ONE. 2013;8:e55237 pubmed publisher
    ..Pharmacological perturbation of the cytoskeleton revealed that cytoplasmic Ngn3 is associated with microtubules. ..
  61. Moreno F, Indakoetxea B, Barandiaran M, Caballero M, Gorostidi A, Calafell F, et al. The unexpected co-occurrence of GRN and MAPT p.A152T in Basque families: Clinical and pathological characteristics. PLoS ONE. 2017;12:e0178093 pubmed publisher
    ..A152T MAPT variant does not appear to show a discernible influence on the clinical phenotype of GRN carriers. Whether p.A152T confers a greater than expected propensity for tau pathology in these GRN carriers remains an open question. ..
  62. Blanco R, Martínez Navarrete G, Valiente Soriano F, Avilés Trigueros M, Pérez Rico C, Serrano Puebla A, et al. The S1P1 receptor-selective agonist CYM-5442 protects retinal ganglion cells in endothelin-1 induced retinal ganglion cell loss. Exp Eye Res. 2017;164:37-45 pubmed publisher
    ..The results of the present study further demonstrate the important role of S1P1 receptor agonists to lessen intravitreal ET-1 induced RGC loss. ..
  63. Martinez Delgado B, Cuadros M, Honrado E, Ruiz de la Parte A, Roncador G, Alves J, et al. Differential expression of NF-kappaB pathway genes among peripheral T-cell lymphomas. Leukemia. 2005;19:2254-63 pubmed
    ..The expression profile associated to reduced expression of NF-kappaB genes was significantly associated with shorter survival of patients and seems to be an independent prognostic factor in a multivariate analysis. ..
  64. Sánchez Camacho C, Lopez J, González A. Basal forebrain cholinergic system of the anuran amphibian Rana perezi: evidence for a shared organization pattern with amniotes. J Comp Neurol. 2006;494:961-75 pubmed
    ..In particular, anurans and mammals (for which most data is available) share a strikingly comparable organization pattern of the BFCS. ..
  65. Roncero I, Sanz C, Alvarez E, Vazquez P, Barrio P, Blazquez E. Glucokinase and glucokinase regulatory proteins are functionally coexpressed before birth in the rat brain. J Neuroendocrinol. 2009;21:973-81 pubmed publisher
    ..Our findings indicate that both proteins may be functionally active before birth and that they can act within a glucose sensor system involved in controlling food intake. ..
  66. Sauer M, Friml J. Immunolocalization of proteins in plants. Methods Mol Biol. 2010;655:253-63 pubmed publisher
    ..Additionally, for bulky or hard tissue types, a variation of this protocol for paraffin-embedded sections is given. ..
  67. Cubelos B, Giménez C, Zafra F. Localization of the GLYT1 glycine transporter at glutamatergic synapses in the rat brain. Cereb Cortex. 2005;15:448-59 pubmed
    ..In conclusion, the close spatial association of GLYT1 and glutamatergic synapses strongly supports a role for this protein in neurotransmission mediated by NMDA receptors in the forebrain, and perhaps in other regions of the CNS. ..
  68. Alelú Paz R, Gimenez Amaya J. Chemical parcellation of the anterior thalamic nuclei in the human brain. J Neural Transm (Vienna). 2007;114:969-81 pubmed
    ..These morphological findings describe a heterogeneous chemical anatomy in the human ATN which may reflect regional differences in the functional organization of the ATN with respect to the other thalamic nuclei and the cerebral cortex. ..
  69. Lara M, Santos M, Ruiz S, Segrelles C, Moral M, Martínez Cruz A, et al. p107 acts as a tumor suppressor in pRb-deficient epidermis. Mol Carcinog. 2008;47:105-13 pubmed
    ..Overall, our data demonstrate that p107 behaves as a tumor suppressor in epidermis in the absence of pRb and suggest novel tumor-suppressive roles for p107 in the context of functional p53 and activated Ras. ..
  70. Martínez Iglesias O, Garcia Silva S, Regadera J, Aranda A. Hypothyroidism enhances tumor invasiveness and metastasis development. PLoS ONE. 2009;4:e6428 pubmed publisher
    ..On the other hand, the finding that hypothyroidism can affect differentially tumor growth and invasiveness can contribute to the explanation of the confounding reports on the influence of thyroidal status in human cancer. ..
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