Experts and Doctors on fluorescent antibody technique in Madrid, Spain


Locale: Madrid, Spain
Topic: fluorescent antibody technique

Top Publications

  1. Jimenez C, Portela R, Mellado M, Rodriguez Frade J, Collard J, Serrano A, et al. Role of the PI3K regulatory subunit in the control of actin organization and cell migration. J Cell Biol. 2000;151:249-62 pubmed
  2. Olmeda D, Jorda M, Peinado H, Fabra A, Cano A. Snail silencing effectively suppresses tumour growth and invasiveness. Oncogene. 2007;26:1862-74 pubmed
    ..These results indicate that use of RNA interference can be an effective tool for blocking Snail function, opening the way for its application in new antiinvasive therapies. ..
  3. Sanchez Mendoza E, Burguete M, Castelló Ruiz M, González M, Roncero C, Salom J, et al. Transient focal cerebral ischemia significantly alters not only EAATs but also VGLUTs expression in rats: relevance of changes in reactive astroglia. J Neurochem. 2010;113:1343-55 pubmed publisher
  4. Tardáguila M, González Gugel E, Sánchez Pacheco A. Aurora kinase B activity is modulated by thyroid hormone during transcriptional activation of pituitary genes. Mol Endocrinol. 2011;25:385-93 pubmed publisher
    ..Our findings reveal a novel role for Aurora kinase B during transcriptional initiation in GO/G1, apart from its well-known mitotic activity. ..
  5. Romero Pérez L, García Sanz P, Mota A, Leskelä S, Hergueta Redondo M, Díaz Martín J, et al. A role for the transducer of the Hippo pathway, TAZ, in the development of aggressive types of endometrial cancer. Mod Pathol. 2015;28:1492-503 pubmed publisher
    ..Together, these data reveal a previously unknown role for TAZ and the Hippo pathway in the progression of aggressive subtypes of endometrial cancer. ..
  6. Garcia Pascual A, Sancho M, Costa G, Triguero D. Interstitial cells of Cajal in the urethra are cGMP-mediated targets of nitrergic neurotransmission. Am J Physiol Renal Physiol. 2008;295:F971-83 pubmed publisher
    ..Together, these results suggest a model of parallel innervation in which both SMC and ICC-M are effectors of nerve-released NO in the urethra. ..
  7. Granado Serrano A, Martin M, Bravo L, Goya L, Ramos S. Quercetin attenuates TNF-induced inflammation in hepatic cells by inhibiting the NF-?B pathway. Nutr Cancer. 2012;64:588-98 pubmed publisher
    ..These observations suggest that quercetin may contribute as an antiinflammatory agent in the liver and provide evidences about its role in the prevention of diseases associated with inflammation, including cancer. ..
  8. Gomez S, Prieto C, Folgueira L. A prospective study to assess the diagnostic performance of the Sofia(®) Immunoassay for Influenza and RSV detection. J Clin Virol. 2016;77:1-4 pubmed publisher
    ..More information is needed regarding the performance for influenza B given the small number of positive samples assessed. ..
  9. Sacedón R, Varas A, Hernández López C, Gutiérrez deFrías C, Crompton T, Zapata A, et al. Expression of hedgehog proteins in the human thymus. J Histochem Cytochem. 2003;51:1557-66 pubmed

More Information

Publications101 found, 100 shown here

  1. Redondo S, Ruiz E, Gordillo Moscoso A, Navarro Dorado J, Ramajo M, Rodriguez E, et al. Overproduction of cyclo-oxygenase-2 (COX-2) is involved in the resistance to apoptosis in vascular smooth muscle cells from diabetic patients: a link between inflammation and apoptosis. Diabetologia. 2011;54:190-9 pubmed publisher
    ..This relationship is not causative and the common production of these two proteins may be co-regulated by shared regulatory elements in diabetes. ..
  2. Valencia J, Hernández López C, Martínez V, Hidalgo L, Zapata A, Vicente A, et al. Wnt5a skews dendritic cell differentiation to an unconventional phenotype with tolerogenic features. J Immunol. 2011;187:4129-39 pubmed publisher
    ..Our results therefore suggest that under high levels of Wnt5a, typical of the inflammatory state and sepsis, monocytes could differentiate into unconventional DCs with tolerogenic features. ..
  3. Fernández López D, Pradillo J, García Yébenes I, Martínez Orgado J, Moro M, Lizasoain I. The cannabinoid WIN55212-2 promotes neural repair after neonatal hypoxia-ischemia. Stroke. 2010;41:2956-64 pubmed publisher
    ..Our results suggest that the activation of the endocannabinoid system promotes white and gray matter recovery after neonatal HI injury. ..
  4. Cannata Ortiz P, Gracia C, Aouad Y, Barat A, Martinez Gonzalez M, Rossello G, et al. Small vessel microembolization and acute glomerulonephritis following infection of aesthetic filler implants. Diagn Pathol. 2016;11:2 pubmed publisher
    ..In conclusion, aesthetic filler implants may cause microembolization into small vessels. Recognition of the characteristic morphology may expedite diagnosis and avoid unnecessary further testing. ..
  5. Serrano Gomez D, Sierra Filardi E, Martinez Nunez R, Caparros E, Delgado R, Muñoz Fernández M, et al. Structural requirements for multimerization of the pathogen receptor dendritic cell-specific ICAM3-grabbing non-integrin (CD209) on the cell surface. J Biol Chem. 2008;283:3889-903 pubmed
  6. Cid Pellitero E, Garzón M. Hypocretin1/OrexinA axon targeting of laterodorsal tegmental nucleus neurons projecting to the rat medial prefrontal cortex. Cereb Cortex. 2011;21:2762-73 pubmed publisher
    ..One-third of the target neurons were ChAT labeled. Hcrt1/OxA excitatory input to LDT neurons projecting to mPFC probably contributes to the wakefulness-enhancing actions of Hcrt/Ox impaired in narcoleptics. ..
  7. Serrano N, Cortegano I, Ruiz C, Alía M, de Andres B, Rejas M, et al. Megakaryocytes promote hepatoepithelial liver cell development in E11.5 mouse embryos by cell-to-cell contact and by vascular endothelial growth factor A signaling. Hepatology. 2012;56:1934-45 pubmed publisher
    ..The cells of the MK lineage present in the developing mouse embryo liver promote the growth of hepatoepithelial cells in vitro through VEGF-A signaling and may play a role in liver development in vivo. ..
  8. Rodríguez Muñoz Y, Martín Vílchez S, Lopez Rodriguez R, Hernández Bartolomé Á, Trapero Marugan M, Borque M, et al. Peripheral blood monocyte subsets predict antiviral response in chronic hepatitis C. Aliment Pharmacol Ther. 2011;34:960-71 pubmed publisher
    ..Hence, the study of monocyte subset regulation might effect improved CHC prognoses and adjuvant therapies. ..
  9. Martínez Moreno M, Alvarez Barrientos A, Roncal F, Albar J, Gavilanes F, Lamas S, et al. Direct interaction between the reductase domain of endothelial nitric oxide synthase and the ryanodine receptor. FEBS Lett. 2005;579:3159-63 pubmed
    ..Immunofluorescence data indicated that a subpopulation of eNOS associates with RyR in perinuclear regions of the cell, where eNOS might be responsible for the known nitrosylation of RyR. ..
  10. Cubelos B, González González I, Giménez C, Zafra F. The scaffolding protein PSD-95 interacts with the glycine transporter GLYT1 and impairs its internalization. J Neurochem. 2005;95:1047-58 pubmed
    ..We hypothesize that PSD-95 might act as a scaffold for GLYT1 and NMDA receptors, allowing GLYT1 to regulate the concentrations of glycine in the micro-environment of NMDA receptors. ..
  11. Vicente S, Perez Rodriguez R, Oliván A, Martínez Palacián A, Gonzalez M, Oset Gasque M. Nitric oxide and peroxynitrite induce cellular death in bovine chromaffin cells: evidence for a mixed necrotic and apoptotic mechanism with caspases activation. J Neurosci Res. 2006;84:78-96 pubmed
    ..These results suggest that chromaffin cells could be good models for investigating the molecular basis of degeneration in diseases showing death of catecholaminergic neurons, phenomenon in which NO plays an important role. ..
  12. Martín Acebes M, Blazquez A, Jiménez de Oya N, Escribano Romero E, Saiz J. West Nile virus replication requires fatty acid synthesis but is independent on phosphatidylinositol-4-phosphate lipids. PLoS ONE. 2011;6:e24970 pubmed publisher
    ..Similar features were found when infection by other flavivirus, the Usutu virus (USUV), was analyzed. These features of WNV replication could help to design specific antiviral approaches against WNV and other related flaviviruses. ..
  13. Martinez Torrecuadrada J, Cheung L, López Serra P, Barderas R, Canamero M, Ferreiro S, et al. Antitumor activity of fibroblast growth factor receptor 3-specific immunotoxins in a xenograft mouse model of bladder carcinoma is mediated by apoptosis. Mol Cancer Ther. 2008;7:862-73 pubmed publisher
    ..These results show that FGFR3-driven immunotoxins may be an effective therapeutic agent against human bladder and other tumor types overexpressing FGFR3. ..
  14. Rodriguez Pinilla S, Roncador G, Rodriguez Peralto J, Mollejo M, Garcia J, Montes Moreno S, et al. Primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoma expresses follicular T-cell markers. Am J Surg Pathol. 2009;33:81-90 pubmed publisher
    ..Moreover, these findings suggest that B-cell stimulation by FTH could also take place in some cutaneous T-cell lymphomas. ..
  15. Luque García J, Martínez Torrecuadrada J, Epifano C, Canamero M, Babel I, Casal J. Differential protein expression on the cell surface of colorectal cancer cells associated to tumor metastasis. Proteomics. 2010;10:940-52 pubmed publisher
    ..In summary, the identified proteins provide us with a better understanding of the events involved in liver colonization and CRC metastasis. ..
  16. Magdaleno L, Gasset M, Varea J, Schambony A, Urbanke C, Raida M, et al. Biochemical and conformational characterisation of HSP-3, a stallion seminal plasma protein of the cysteine-rich secretory protein (CRISP) family. FEBS Lett. 1997;420:179-85 pubmed
    ..Analysis of the spectroscopic and calorimetric data indicates the occurrence of aggregation of denatured HSP-3 molecules and suggests the monomer as the cooperative unfolding unit. ..
  17. Pardo B, Rodrigues T, Contreras L, Garzón M, Llorente Folch I, Kobayashi K, et al. Brain glutamine synthesis requires neuronal-born aspartate as amino donor for glial glutamate formation. J Cereb Blood Flow Metab. 2011;31:90-101 pubmed publisher
    ..This pathway may provide a mechanism to transfer neuronal-born redox equivalents to mitochondria in astrocytes. ..
  18. Longo N, Yanez Mo M, Mittelbrunn M, de la Rosa G, Munoz M, Sanchez Madrid F, et al. Regulatory role of tetraspanin CD9 in tumor-endothelial cell interaction during transendothelial invasion of melanoma cells. Blood. 2001;98:3717-26 pubmed
  19. Moreno N, Morona R, Lopez J, Muñoz M, González A. Lateral and medial amygdala of anuran amphibians and their relation to olfactory and vomeronasal information. Brain Res Bull. 2005;66:332-6 pubmed
    ..This supports the notion that all tetrapods share a common pattern of organization of the amygdaloid complex, which links environmental (olfactory/vomeronasal) information and the behavioural response of the animal. ..
  20. Diaz Hernandez M, Moreno Herrero F, Gómez Ramos P, Morán M, Ferrer I, Baró A, et al. Biochemical, ultrastructural, and reversibility studies on huntingtin filaments isolated from mouse and human brain. J Neurosci. 2004;24:9361-71 pubmed
  21. Ordóñez Morán P, Irmisch A, Barbachano A, Chicote I, Tenbaum S, Landolfi S, et al. SPROUTY2 is a ?-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer. Oncogene. 2014;33:1975-85 pubmed publisher
    ..Importantly, the amount of SPRY2 protein correlated with shorter overall survival of colon cancer patients. Our data reveal SPRY2 as a novel Wnt/?-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer. ..
  22. Merino Gracia J, Costas Insua C, Canales M, Rodríguez Crespo I. Insights into the C-terminal Peptide Binding Specificity of the PDZ Domain of Neuronal Nitric-oxide Synthase: CHARACTERIZATION OF THE INTERACTION WITH THE TIGHT JUNCTION PROTEIN CLAUDIN-3. J Biol Chem. 2016;291:11581-95 pubmed publisher
    ..Finally, we have analyzed the high affinity association of the PDZ domain of nNOS to claudin-3 and claudin-14, two tight junction tetraspan membrane proteins that are essential components of the paracellular barrier. ..
  23. Nombela Arrieta C, Lacalle R, Montoya M, Kunisaki Y, Megias D, Marqués M, et al. Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing. Immunity. 2004;21:429-41 pubmed
    ..DOCK2 and PI3Kgamma thus play distinct roles during T and B cell integrin activation and migration. ..
  24. Martín Acebes M, Blazquez A, de Oya N, Escribano Romero E, Shi P, Saiz J. A single amino acid substitution in the core protein of West Nile virus increases resistance to acidotropic compounds. PLoS ONE. 2013;8:e69479 pubmed publisher
    ..The findings here reported unveil a non-previously assessed connection between the C viral protein and the acidic pH necessary for entry and proper exit of flaviviruses. ..
  25. Trakala M, Partida D, Salazar Roa M, Maroto M, Wachowicz P, de Cárcer G, et al. Activation of the endomitotic spindle assembly checkpoint and thrombocytopenia in Plk1-deficient mice. Blood. 2015;126:1707-14 pubmed publisher
    ..SAC activation results in defective maturation of megakaryocytes and cell death, thus raising a note of caution in the use of Plk1 inhibitors in therapeutic strategies based on polyploidization regulators. ..
  26. Andres G, Alejo A, Simón Mateo C, Salas M. African swine fever virus protease, a new viral member of the SUMO-1-specific protease family. J Biol Chem. 2001;276:780-7 pubmed
    ..The identification of the ASFV protease will allow a better understanding of the role of polyprotein processing in virus assembly and may contribute to our knowledge of the emerging family of SUMO-1-specific proteases. ..
  27. Barabási B, Csondor A, Martín Pozas T, Pulupa Sánchez A, Antalffy G, Siklós L, et al. Effect of axotomy and 17β-estradiol on P2X7 receptor expression pattern in the hypoglossal nucleus of ovariectomized mice. Neuroscience. 2016;319:107-15 pubmed publisher
    ..Our results suggest that axotomy induces cell-type specific changes in P2X7 receptor expression, which may be directly regulated by 17β-estradiol through ER alpha or beta in neurons, but not in activated microglia. ..
  28. Larriba M, Martín Villar E, Garcia J, Pereira F, Peña C, De Herreros A, et al. Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer. Carcinogenesis. 2009;30:1459-68 pubmed publisher
    ..However, VDR downregulation is higher in tumors coexpressing SNAI2 and SNAI1 than in those expressing only one of these genes. Together, these data indicate that Snail2 and Snail1 cooperate for VDR repression in colon cancer. ..
  29. Grijota Martinez C, Diez D, Morreale de Escobar G, Bernal J, Morte B. Lack of action of exogenously administered T3 on the fetal rat brain despite expression of the monocarboxylate transporter 8. Endocrinology. 2011;152:1713-21 pubmed publisher
    ..The data indicate that T4, through local deiodination, provides most T3 in the fetal rat brain. The role of Mct8 as a T3 transporter in the fetal rat brain is therefore uncertain. ..
  30. Pelayo H, Lastres P, De la Torre C. Replication and G2 checkpoints: their response to caffeine. Planta. 2001;212:444-53 pubmed
    ..Moreover, it seems to enforce the checkpoint that controls the completion of DNA synthesis, as the appearance of the late wave of normal mitoses produced in the presence of hydroxyurea was prevented by the use of caffeine. ..
  31. Martin P, Villares R, Rodriguez Mascarenhas S, Zaballos A, Leitges M, Kovac J, et al. Control of T helper 2 cell function and allergic airway inflammation by PKCzeta. Proc Natl Acad Sci U S A. 2005;102:9866-71 pubmed
    ..Moreover, PKCzeta-/- mice display dramatic inhibition of ovalbumin-induced allergic airway disease, strongly suggesting that PKCzeta can be a therapeutic target in asthma. ..
  32. Moran M, Rivera H, Sánchez Aragó M, Blazquez A, Merinero B, Ugalde C, et al. Mitochondrial bioenergetics and dynamics interplay in complex I-deficient fibroblasts. Biochim Biophys Acta. 2010;1802:443-53 pubmed publisher
    ..The different genetic backgrounds of patients with OXPHOS disorders would explain, at least partially, differences in the pathophysiological manifestations of CI deficiency. ..
  33. Martín Cófreces N, Baixauli F, Lopez M, Gil D, Monjas A, Alarcon B, et al. End-binding protein 1 controls signal propagation from the T cell receptor. EMBO J. 2012;31:4140-52 pubmed publisher
    ..These results identify a role for EB1 interaction with the TCR in controlling TCR sorting and its connection with the LAT/PLC?1 signalosome. ..
  34. Díaz Alonso J, Aguado T, Wu C, Palazuelos J, Hofmann C, Garcez P, et al. The CB(1) cannabinoid receptor drives corticospinal motor neuron differentiation through the Ctip2/Satb2 transcriptional regulation axis. J Neurosci. 2012;32:16651-65 pubmed publisher
  35. Diaz Guerra M, Haddow S, Bauluz C, Jorcano J, Cano A, Balmain A, et al. Expression of simple epithelial cytokeratins in mouse epidermal keratinocytes harboring Harvey ras gene alterations. Cancer Res. 1992;52:680-7 pubmed
    ..Our results suggest that activation of a H-ras gene can alter the normal differentiation program of epidermal cells and that the ability to synthesize CK8 and CK18 could be related to tumor progression...
  36. Lopez Longo F, Rodriguez Mahou M, Escalona Monge M, Gonzalez C, Monteagudo I, Carreño Perez L. Simultaneous identification of various antinuclear antibodies using an automated multiparameter line immunoassay system. Lupus. 2003;12:623-9 pubmed
    ..Its most notable advantages are automated simultaneous detection of several autoantibodies in the same serum and its lower cost compared with ELISA techniques. ..
  37. Prados B, Peña A, Cotarelo R, Valero M, Cruces J. Expression of the murine Pomt1 gene in both the developing brain and adult muscle tissues and its relationship with clinical aspects of Walker-Warburg syndrome. Am J Pathol. 2007;170:1659-68 pubmed
    ..This expression pattern in the testes could also be related to the gonadal anomalies observed in some patients with WWS. ..
  38. Rubio A, Perez M, de Lecea L, Avila J. Effect of cortistatin on tau phosphorylation at Ser262 site. J Neurosci Res. 2008;86:2462-75 pubmed publisher
    ..Our results suggest an important role for cortistatin in the regulation of tau phosphorylation that may be associated with the pathophysiology of Alzheimer's disease in regions such as the cerebral cortex. ..
  39. Barrero Villar M, Barroso González J, Cabrero J, Gordón Alonso M, Alvarez Losada S, Munoz Fernandez M, et al. PI4P5-kinase Ialpha is required for efficient HIV-1 entry and infection of T cells. J Immunol. 2008;181:6882-8 pubmed
    ..These data indicate that PI4P5-K Ialpha-mediated PIP(2) production is crucial for HIV-1 entry and the early steps of infection in permissive lymphocytes. ..
  40. Fernández Sánchez E, Martínez Villarreal J, Giménez C, Zafra F. Constitutive and regulated endocytosis of the glycine transporter GLYT1b is controlled by ubiquitination. J Biol Chem. 2009;284:19482-92 pubmed publisher
    ..It remains to be determined whether GLYT1b recycling might be affected in pathologies involving alterations to the ubiquitin system, thereby interfering with its influence on inhibitory and excitatory neurotransmission. ..
  41. Di Lisio L, Gomez Lopez G, Sanchez Beato M, Gomez Abad C, Rodriguez M, Villuendas R, et al. Mantle cell lymphoma: transcriptional regulation by microRNAs. Leukemia. 2010;24:1335-42 pubmed publisher
    ..In summary, using a novel bioinformatics approach, this study identified miRNA changes that contribute to MCL pathogenesis and markers of potential utility in MCL diagnosis and clinical prognostication. ..
  42. Mirasierra M, Fernandez Perez A, Díaz Prieto N, Vallejo M. Alx3-deficient mice exhibit decreased insulin in beta cells, altered glucose homeostasis and increased apoptosis in pancreatic islets. Diabetologia. 2011;54:403-14 pubmed publisher
    ..We suggest that ALX3 constitutes a potential candidate to consider in the aetiopathogenesis of diabetes mellitus. ..
  43. Ruiz Sáenz A, Kremer L, Alonso M, Millan J, Correas I. Protein 4.1R regulates cell migration and IQGAP1 recruitment to the leading edge. J Cell Sci. 2011;124:2529-38 pubmed publisher
    ..1R localization. Collectively, our results indicate a crucial role for protein 4.1R in cell migration and in the recruitment of the scaffold protein IQGAP1 to the cell front. ..
  44. Duchene J, Novitzky Basso I, Thiriot A, Casanova Acebes M, Bianchini M, Etheridge S, et al. Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis. Nat Immunol. 2017;18:753-761 pubmed publisher
  45. Bellon T, Lopez Rodriguez C, Rubio M, Jochems G, Bernabeu C, Corbi A. Regulated expression of p150,95 (CD11c/CD18; alpha X/beta 2) and VLA-4 (CD49d/CD29; alpha 4/beta 1) integrins during myeloid cell differentiation. Eur J Immunol. 1994;24:41-7 pubmed
  46. Marazuela M, Martin Belmonte F, García López M, Aranda J, de Marco M, Alonso M. Expression and distribution of MAL2, an essential element of the machinery for basolateral-to-apical transcytosis, in human thyroid epithelial cells. Endocrinology. 2004;145:1011-6 pubmed
  47. Riol Blanco L, Delgado Martín C, Sanchez Sanchez N, Alonso C L, Gutierrez Lopez M, Del Hoyo G, et al. Immunological synapse formation inhibits, via NF-kappaB and FOXO1, the apoptosis of dendritic cells. Nat Immunol. 2009;10:753-60 pubmed publisher
    ..Direct stimulation of the IS component CD40 on DCs leads to the activation of Akt1, suggesting the involvement of this receptor in the antiapoptotic effects observed upon IS formation. ..
  48. Hurtado Chong A, Yusta Boyo M, Vergaño Vera E, Bulfone A, de Pablo F, Vicario Abejón C. IGF-I promotes neuronal migration and positioning in the olfactory bulb and the exit of neuroblasts from the subventricular zone. Eur J Neurosci. 2009;30:742-55 pubmed publisher
    ..These findings suggest that IGF-I promotes neuronal positioning in the OB and support a role for IGF-I in stimulating neuroblast exit from the SVZ into the RMS, thereby promoting the incorporation of newly formed neurons into the OB. ..
  49. González A, Northcutt R. An immunohistochemical approach to lungfish telencephalic organization. Brain Behav Evol. 2009;74:43-55 pubmed publisher
  50. López Fontal R, Zeini M, Traves P, Gomez Ferreria M, Aranda A, Saez G, et al. Mice lacking thyroid hormone receptor Beta show enhanced apoptosis and delayed liver commitment for proliferation after partial hepatectomy. PLoS ONE. 2010;5:e8710 pubmed publisher
    ..Taken together, these results indicate that TRbeta contributes significantly to the rapid initial round of hepatocyte proliferation following PH, and improves the survival of the regenerating liver at later times. ..
  51. Lopez J, Morona R, González A. Immunohistochemical localization of DARPP-32 in the brain and spinal cord of anuran amphibians and its relation with the catecholaminergic system. J Chem Neuroanat. 2010;40:325-38 pubmed publisher
    ..However, in general, the distribution of DARPP-32 in the brain of the anuran amphibians resembles in many aspects the pattern observed in amniotes, especially in reptiles. ..
  52. Sanchez Nino M, Poveda J, Sanz A, Mezzano S, Carrasco S, Fernández Fernández B, et al. Fn14 in podocytes and proteinuric kidney disease. Biochim Biophys Acta. 2013;1832:2232-43 pubmed publisher
    ..In conclusion, Fn14 activation results in NF?B-mediated pro-inflammatory effects on podocytes that may be relevant for the pathogenesis of non-proliferative proteinuric kidney disease of non-immune origin. ..
  53. Puertollano R, Alonso M. MAL, an integral element of the apical sorting machinery, is an itinerant protein that cycles between the trans-Golgi network and the plasma membrane. Mol Biol Cell. 1999;10:3435-47 pubmed
    ..Together, these observations suggest that, as predicted for integral membrane members of the late protein transport machinery, MAL is an itinerant protein cycling between the TGN and the plasma membrane. ..
  54. Yus Najera E, Munoz A, Salvador N, Jensen B, Rasmussen H, Defelipe J, et al. Localization of KCNQ5 in the normal and epileptic human temporal neocortex and hippocampal formation. Neuroscience. 2003;120:353-64 pubmed
  55. Gómez R, Valdeolmillos A, Parra M, Viera A, Carreiro C, Roncal F, et al. Mammalian SGO2 appears at the inner centromere domain and redistributes depending on tension across centromeres during meiosis II and mitosis. EMBO Rep. 2007;8:173-80 pubmed
    ..We propose a model by which the redistribution of SGO2 would unmask cohesive centromere proteins, which would be then released or cleaved by separase, to trigger chromatid segregation to opposite poles. ..
  56. Innamorato N, Jazwa A, Rojo A, Garcia C, Fernandez Ruiz J, Grochot Przeczek A, et al. Different susceptibility to the Parkinson's toxin MPTP in mice lacking the redox master regulator Nrf2 or its target gene heme oxygenase-1. PLoS ONE. 2010;5:e11838 pubmed publisher
  57. Cerezo Guisado M, del Reino P, Remy G, Kuma Y, Arthur J, Gallego Ortega D, et al. Evidence of p38? and p38? involvement in cell transformation processes. Carcinogenesis. 2011;32:1093-9 pubmed publisher
    ..Our results indicate that p38? and p38? have a role in the suppression of tumor development. ..
  58. Millan J, Puertollano R, Fan L, Alonso M. Caveolin and MAL, two protein components of internal detergent-insoluble membranes, are in distinct lipid microenvironments in MDCK cells. Biochem Biophys Res Commun. 1997;233:707-12 pubmed
    ..The observed heterogeneity within the internal glycolipid-enriched membrane fraction suggests the existence of distinct specialized lipid microenvironments in MDCK cells. ..
  59. Gonzalez Billault C, Engelke M, Jimenez Mateos E, Wandosell F, Caceres A, Avila J. Participation of structural microtubule-associated proteins (MAPs) in the development of neuronal polarity. J Neurosci Res. 2002;67:713-9 pubmed
    ..Together these results show a synergistic role for MAP1B/MAP2 and MAP1B/TAU. ..
  60. Cubelos B, Giménez C, Zafra F. Localization of the GLYT1 glycine transporter at glutamatergic synapses in the rat brain. Cereb Cortex. 2005;15:448-59 pubmed
    ..In conclusion, the close spatial association of GLYT1 and glutamatergic synapses strongly supports a role for this protein in neurotransmission mediated by NMDA receptors in the forebrain, and perhaps in other regions of the CNS. ..
  61. Trinidad E, Ballesteros M, Zuloaga J, Zapata A, Alonso Colmenar L. An impaired transendothelial migration potential of chronic lymphocytic leukemia (CLL) cells can be linked to ephrin-A4 expression. Blood. 2009;114:5081-90 pubmed publisher
    ..Our results suggest that EFNA4-EphA2 interactions are involved in CLL cell trafficking between blood and the tissues and therefore may become a therapeutic target in the future. ..
  62. Agudo M, Abad J, Molina I, Losada A, Ripoll P, Villasante A. A dicentric chromosome of Drosophila melanogaster showing alternate centromere inactivation. Chromosoma. 2000;109:190-6 pubmed
    ..The involvement of telomere-related sequences in centromere function is discussed. ..
  63. Hurtado O, Lizasoain I, Fernández Tomé P, Alvarez Barrientos A, Leza J, Lorenzo P, et al. TACE/ADAM17-TNF-alpha pathway in rat cortical cultures after exposure to oxygen-glucose deprivation or glutamate. J Cereb Blood Flow Metab. 2002;22:576-85 pubmed
  64. Samaniego R, de la Torre C, Moreno Díaz de la Espina S. Dynamics of replication foci and nuclear matrix during S phase in Allium cepa L. cells. Planta. 2002;215:195-204 pubmed
  65. Andres Mateos E, Renart J, Cruces J, Solís Garrido L, Serantes R, de Lucas Cerrillo A, et al. Dynamic association of the Ca2+ channel alpha1A subunit and SNAP-25 in round or neurite-emitting chromaffin cells. Eur J Neurosci. 2005;22:2187-98 pubmed
  66. Martín Villar E, Megias D, Castel S, Yurrita M, Vilaró S, Quintanilla M. Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition. J Cell Sci. 2006;119:4541-53 pubmed
    ..These results provide a mechanistic basis to understand the role of podoplanin in cell migration or invasiveness. ..
  67. Peinado H, Moreno Bueno G, Hardisson D, Perez Gomez E, Santos V, Mendiola M, et al. Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas. Cancer Res. 2008;68:4541-50 pubmed publisher
    ..Altogether, our results show that LOXL2 can be used as a new poor prognosis indicator in human squamous cell carcinomas promoting malignant transformation by both SNAI1-dependent and SNAI1-independent pathways. ..
  68. Franco A, Knafo S, Bañón Rodríguez I, Merino Serrais P, Fernaud Espinosa I, Nieto M, et al. WIP is a negative regulator of neuronal maturation and synaptic activity. Cereb Cortex. 2012;22:1191-202 pubmed publisher
    ..These findings reveal WIP as a previously unreported regulator of neuronal maturation and synaptic activity. ..
  69. Gálvez Santisteban M, Rodriguez Fraticelli A, Bryant D, Vergarajauregui S, Yasuda T, Bañón Rodríguez I, et al. Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cells. Nat Cell Biol. 2012;14:838-49 pubmed publisher
    ..Together, Slp2-a/4-a coordinate the spatiotemporal organization of vectorial apical transport to ensure that only a single apical surface, and thus the formation of a single lumen, occurs per cell. ..
  70. Lastres Becker I, Innamorato N, Jaworski T, Rabano A, Kügler S, Van Leuven F, et al. Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis. Brain. 2014;137:78-91 pubmed publisher
    ..Our combined results indicate that fractalkine mobilizes NRF2 to limit over-activation of microglia and identify this new target to control unremitting neuroinflammation in tauopathies. ..
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