Experts and Doctors on hypertension in Dundee, KwaZulu Natal, South Africa


Locale: Dundee, KwaZulu Natal, South Africa
Topic: hypertension

Top Publications

  1. Parthasarathy H, Alhashmi K, McMahon A, Struthers A, Connell J, McInnes G, et al. Does the aldosterone:renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study. BMC Cardiovasc Disord. 2007;7:14 pubmed
    ..Hence treating hypertension with specific aldosterone antagonists may be a better approach in this group of patients. It may lead on to better blood pressures with fewer medications. ..
  2. Richardson C, Rafiqi F, Karlsson H, Moleleki N, Vandewalle A, Campbell D, et al. Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1. J Cell Sci. 2008;121:675-84 pubmed publisher
    ..They also suggest a mechanism by which increased WNK1 overexpression could lead to hypertension and that inhibitors of SPAK/OSR1 might be of use in reducing blood pressure by suppressing phosphorylation and hence activity of NCC. ..
  3. Ang D, Fahey T, Wright G, Struthers A. Development and validation of a clinical score to identify echocardiographic left ventricular hypertrophy in patients with cardiovascular disease. Am J Hypertens. 2008;21:1011-7 pubmed publisher
    ..This will help target precious echo resources toward individuals who are most likely to have this condition. This could potentially lead to better risk stratification in this patient population. ..