Experts and Doctors on animals in Andong, Gyeongsangbuk do, South Korea


Locale: Andong, Gyeongsangbuk do, South Korea
Topic: animals

Top Publications

  1. Jeong J, Jeong H. Rheosmin, a naturally occurring phenolic compound inhibits LPS-induced iNOS and COX-2 expression in RAW264.7 cells by blocking NF-kappaB activation pathway. Food Chem Toxicol. 2010;48:2148-53 pubmed publisher
    ..This result shows that rheosmin inhibits NF-kappaB activation. In conclusion, our results suggest that rheosmin inhibits LPS-induced iNOS and COX-2 expression in RAW264.7 cells by blocking NF-kappaB activation pathway. ..
  2. Nalini M, Choi J, Je Y, Hwang I, Kim Y. Immunoevasive property of a polydnaviral product, CpBV-lectin, protects the parasitoid egg from hemocytic encapsulation of Plutella xylostella (Lepidoptera: Yponomeutidae). J Insect Physiol. 2008;54:1125-31 pubmed publisher
    ..These results suggest that CpBV-lectin interferes with hemocyte recognition by masking hemocyte-binding sites on the parasitoid eggs. ..
  3. Ji D, Yi Y, Kang G, Choi Y, Kim P, Baek N, et al. Identification of an antibacterial compound, benzylideneacetone, from Xenorhabdus nematophila against major plant-pathogenic bacteria. FEMS Microbiol Lett. 2004;239:241-8 pubmed
    ..This study reports a new antibiotic compound synthesized by X. nematophila, which is a monoterpenoid compound and active against some Gram-negative bacteria. ..
  4. Kil E, Kim S, Lee Y, Byun H, Park J, Seo H, et al. Tomato yellow leaf curl virus (TYLCV-IL): a seed-transmissible geminivirus in tomatoes. Sci Rep. 2016;6:19013 pubmed publisher
    ..Taken together, TYLCV-IL can be transmitted via seeds, and tomato plants germinated from TYLCV-infected seeds can be an inoculum source of TYLCV. This is the first report about TYLCV seed transmission in tomato. ..
  5. Alcantara E, Shin M, Feldmann J, Nixon G, Beattie J, Kwun I. Long-term zinc deprivation accelerates rat vascular smooth muscle cell proliferation involving the down-regulation of JNK1/2 expression in MAPK signaling. Atherosclerosis. 2013;228:46-52 pubmed publisher
    ..The findings suggested that zinc may have anti-VSMC proliferative properties in atherosclerosis. ..
  6. Ibrahim A, Choi J, Je Y, Kim Y. Protein tyrosine phosphatases encoded in Cotesia plutellae bracovirus: sequence analysis, expression profile, and a possible biological role in host immunosuppression. Dev Comp Immunol. 2007;31:978-90 pubmed
    ..xylostella. These results suggest that CpBV-PTPs are expressed in the parasitized P. xylostella and affect cellular PTP activity, which may be associated with host immunosuppression. ..
  7. Jeong J, Hong S, Jeong H. 3,4-dihydroxybenzaldehyde purified from the barley seeds (Hordeum vulgare) inhibits oxidative DNA damage and apoptosis via its antioxidant activity. Phytomedicine. 2009;16:85-94 pubmed publisher
    ..These results suggest that the barley may exert the inhibitory effect on H(2)O(2)-induced tumor development by blocking H(2)O(2)-induced oxidative DNA damage, cell death and apoptosis. ..
  8. Jeong H, Jeong J, Hsieh C, Hernández Ledesma B, de Lumen B. Lunasin is prevalent in barley and is bioavailable and bioactive in in vivo and in vitro studies. Nutr Cancer. 2010;62:1113-9 pubmed publisher
    ..We conclude that lunasin is prevalent in barley, bioavailable, and bioactive and that consumption of barley could play an important role of cancer prevention in barley-consuming populations. ..
  9. Cho Y, Alcantara E, Kumaran S, Son K, Sohn H, Lee J, et al. Red yeast rice stimulates osteoblast proliferation and increases alkaline phosphatase activity in MC3T3-E1 cells. Nutr Res. 2010;30:501-10 pubmed publisher
    ..The results imply that RYRP extract may increase osteogenic effect by stimulating cell proliferation and ALP activity in osteoblastic cells. ..

More Information


  1. Park Y, Kim Y. Xenorhabdus nematophilus inhibits p-bromophenacyl bromide (BPB)-sensitive PLA2 of Spodoptera exigua. Arch Insect Biochem Physiol. 2003;54:134-42 pubmed
    ..These results indicate that X. nematophilus produces and secretes PLA2 inhibitor, which acts on BPB-susceptible PLA2 of S. exigua...
  2. Barandoc K, Kim Y. Translation inhibitory factors encoded in Cotesia plutellae bracovirus require the 5'-UTR of a host mRNA target. Comp Biochem Physiol B Biochem Mol Biol. 2010;156:129-36 pubmed publisher
    ..This study suggests that CpBV15alpha and CpBV15beta inhibit host mRNAs directly by acting on translation machinery, in which 5'-UTR of target mRNAs would be required for the inhibitory action...
  3. Park B, Kim Y. Transient transcription of a putative RNase containing BEN domain encoded in Cotesia plutellae bracovirus induces an immunosuppression of the diamondback moth, Plutella xylostella. J Invertebr Pathol. 2010;105:156-63 pubmed publisher
    ..These results suggest that a putative RNase fused with a BEN domain encoded in CpBV-S3 plays a parasitic role in inducing host immunosuppression in the parasitism. ..
  4. Jeong J, Jeong H. 2-Methoxy-4-vinylphenol can induce cell cycle arrest by blocking the hyper-phosphorylation of retinoblastoma protein in benzo[a]pyrene-treated NIH3T3 cells. Biochem Biophys Res Commun. 2010;400:752-7 pubmed publisher
    ..Our results suggest that 2M4VP induce growth arrest of BaP-treated NIH 3T3 cells by blocking the hyper-phosphorylation of Rb via regulating the expression of cell cycle-related proteins. ..
  5. Son Y, Kim Y. Immunosuppression induced by entomopathogens is rescued by addition of apolipophorin III in the diamondback moth, Plutella xylostella. J Invertebr Pathol. 2011;106:217-22 pubmed publisher
    ..This study suggests that ApoLpIII limits pathogenicity induced by parasitization or bacterial infection in P. xylostella. ..
  6. Surakasi V, Mohamed A, Kim Y. RNA interference of ?1 integrin subunit impairs development and immune responses of the beet armyworm, Spodoptera exigua. J Insect Physiol. 2011;57:1537-44 pubmed publisher
    ..exigua during immature development. These results suggest that ?Se1 plays crucial roles in performing cellular immune responses as well as larval development in S. exigua. ..
  7. Hwang J, Kim Y. RNA interference of an antimicrobial peptide, gloverin, of the beet armyworm, Spodoptera exigua, enhances susceptibility to Bacillus thuringiensis. J Invertebr Pathol. 2011;108:194-200 pubmed publisher
    ..These results suggest that Seglv acts as an antimicrobial peptide especially against Gram-positive bacteria including B. thuringiensis. ..
  8. Kumar S, Jung J, Kim Y. Characterization of joining sites of a viral histone H4 on host insect chromosomes. PLoS ONE. 2017;12:e0177066 pubmed publisher
    ..These results indicate that CpBV-H4 joins specific chromatin regions of P. xylostella and controls about one sixth of the total host genes that were regulated by C. plutellae parasitism in an epigenetic mode. ..
  9. Kim M, Lee S, Chun Y, Na J, Kwon H, Kim W, et al. Heat Tolerance Induction of the Indian Meal Moth (Lepidoptera: Pyralidae) Is Accompanied by Upregulation of Heat Shock Proteins and Polyols. Environ Entomol. 2017;46:1005-1011 pubmed publisher
    ..interpunctella. These results suggest that the induction of heat tolerance in P. interpunctella involves the upregulation of these heat shock proteins and hemolymph polyol levels. ..
  10. Bae S, Kim Y. Host physiological changes due to parasitism of a braconid wasp, Cotesia plutellae, on diamondback moth, Plutella xylostella. Comp Biochem Physiol A Mol Integr Physiol. 2004;138:39-44 pubmed
    ..Here, we show that C. plutellae has an endosymbiotic virus like other reported species in Microgastrinae, and suggest that it causes host developmental arrest and immune-depression at parasitization. ..
  11. Jeong H, Jeong J, Kim D, Park J, Lee J, Kweon D, et al. The cancer preventive peptide lunasin from wheat inhibits core histone acetylation. Cancer Lett. 2007;255:42-8 pubmed
    ..The amounts of lunasin in the developing seeds and in the rat liver correlated extremely well with the extent of inhibition of core histone acetylation. ..
  12. Gad W, Kim Y. N-terminal tail of a viral histone H4 encoded in Cotesia plutellae bracovirus is essential to suppress gene expression of host histone H4. Insect Mol Biol. 2009;18:111-8 pubmed publisher
    ..This study suggests that the viral H4 encoded in CpBV can alter host gene expression with its extended N-terminal tail...
  13. Kim Y, Ji D, Cho S, Park Y. Two groups of entomopathogenic bacteria, Photorhabdus and Xenorhabdus, share an inhibitory action against phospholipase A2 to induce host immunodepression. J Invertebr Pathol. 2005;89:258-64 pubmed
    ..bovienni, X. poinarii, and P. luminescens) involved in these two genera. All our experiments clearly showed that these other bacteria also share their inhibitory action against PLA2 to induce host immunodepression...
  14. Gad W, Kim Y. A viral histone H4 encoded by Cotesia plutellae bracovirus inhibits haemocyte-spreading behaviour of the diamondback moth, Plutella xylostella. J Gen Virol. 2008;89:931-8 pubmed publisher
    ..These results suggest that CpBV H4 plays a critical role in suppressing host immune responses during parasitization...
  15. Hong S, Kwon J, Shin J, Kim J, Minai Tehrani A, Yu K, et al. Therapeutic effect of Broussonetia papyrifera and Lonicera japonica in ovalbumin-induced murine asthma model. Nat Prod Commun. 2013;8:1609-14 pubmed
    ..papyrifera and L. japonica treated groups. Taken together, these results clearly indicate that the B. papyrifera and L. japonica extracts may be very effective against asthma and inflammation related diseases...
  16. Hepat R, Kim Y. Transient expression of a viral histone H4 inhibits expression of cellular and humoral immune-associated genes in Tribolium castaneum. Biochem Biophys Res Commun. 2011;415:279-83 pubmed publisher
    ..These results suggest that CpBV-H4 suppresses both humoral and cellular immune responses of T. castaneum by altering a normal epigenetic control of immune-associated gene expression...
  17. Srikanth K, Park J, Stanley D, Kim Y. Plasmatocyte-spreading peptide influences hemocyte behavior via eicosanoids. Arch Insect Biochem Physiol. 2011;78:145-60 pubmed publisher
    ..Taken together, these points strongly support our model showing that PSP acts via a plasmatocyte-surface receptor, which stimulates biosynthesis of the PGs responsible for mediating plasmatocytes spreading. ..
  18. Hepat R, Song J, Lee D, Kim Y. A viral histone h4 joins to eukaryotic nucleosomes and alters host gene expression. J Virol. 2013;87:11223-30 pubmed publisher
    ..These findings suggest that the viral histone H4 alters host gene expression by a direct molecular interaction with insect nucleosomes. ..
  19. Bae S, Kim Y. IkB genes encoded in Cotesia plutellae bracovirus suppress an antiviral response and enhance baculovirus pathogenicity against the diamondback moth, Plutella xylostella. J Invertebr Pathol. 2009;102:79-87 pubmed publisher
    ..When nonparasitized larvae were orally administered with a recombinant baculovirus containing CpBV-IkB, they showed a significant reduction in midgut melanotic response and an enhanced susceptibility to the baculovirus infectivity. ..
  20. Nalini M, Kim Y. A putative protein translation inhibitory factor encoded by Cotesia plutellae bracovirus suppresses host hemocyte-spreading behavior. J Insect Physiol. 2007;53:1283-92 pubmed
    ..Upon incubation of hemocytes with either CpBV15beta or cycloheximide, their ability to release protein molecules was markedly inhibited. This study suggests that CpBV15beta suppresses hemocyte behavior by inhibiting protein translation. ..
  21. Shrestha S, Kim Y. Eicosanoids mediate prophenoloxidase release from oenocytoids in the beet armyworm Spodoptera exigua. Insect Biochem Mol Biol. 2008;38:99-112 pubmed
    ..These results indicate that eicosanoids mediate SePPO activation only at the post-transcriptional level by inducing release of PPO from oenocytoids through cell rupture. ..
  22. Son I, Kim J, Sohn H, Son K, Kim J, Kwon C. Antioxidative and hypolipidemic effects of diosgenin, a steroidal saponin of yam (Dioscorea spp.), on high-cholesterol fed rats. Biosci Biotechnol Biochem. 2007;71:3063-71 pubmed
    ..5% diosgenin group. These results suggest that diosgenin could be a very useful compound to control hypercholesterolemia by both improving the lipid profile and modulating oxidative stress...
  23. Barandoc K, Kim J, Kim Y. Cotesia plutellae bracovirus suppresses expression of an antimicrobial peptide, cecropin, in the diamondback moth, Plutella xylostella, challenged by bacteria. J Microbiol. 2010;48:117-23 pubmed publisher
    ..These results indicate that PxCec expression is regulated by both immune and developmental processes in P. xylostella. The parasitization by C. plutellae inhibited the expression of PxCec by the wasp's symbiotic virus...
  24. Kwon B, Song S, Choi J, Je Y, Kim Y. Transient expression of specific Cotesia plutellae bracoviral segments induces prolonged larval development of the diamondback moth, Plutella xylostella. J Insect Physiol. 2010;56:650-8 pubmed publisher
    ..xylostella. These results suggest that CpBV can induce prolonged larval development of P. xylostella, and that at least some CpBV-PTPs may contribute to the parasitic role probably by altering titers of developmental hormones. ..
  25. Park Y, Kim Y, Tunaz H, Stanley D. An entomopathogenic bacterium, Xenorhabdus nematophila, inhibits hemocytic phospholipase A2 (PLA2) in tobacco hornworms Manduca sexta. J Invertebr Pathol. 2004;86:65-71 pubmed
    ..These results clearly indicate that X. nematophila inhibits PLA2 activity, and thereby inhibits eicosanoid biosynthesis which leads to immunodepression of the infected hosts. ..
  26. Jeong J, de Lumen B, Jeong H. Lunasin peptide purified from Solanum nigrum L. protects DNA from oxidative damage by suppressing the generation of hydroxyl radical via blocking fenton reaction. Cancer Lett. 2010;293:58-64 pubmed publisher
  27. Shrestha S, Kim Y. Activation of immune-associated phospholipase A2 is functionally linked to Toll/Imd signal pathways in the red flour beetle, Tribolium castaneum. Dev Comp Immunol. 2010;34:530-7 pubmed publisher
    ..These results suggest that recognition of bacterial challenge initiates Toll and Imd pathways in T. castaneum, which subsequently induces the activation of immune-associated PLA(2)s as well as gene expression of various AMPs...
  28. Shrestha S, Park Y, Stanley D, Kim Y. Genes encoding phospholipases A2 mediate insect nodulation reactions to bacterial challenge. J Insect Physiol. 2010;56:324-32 pubmed publisher
    ..Identifying specific sPLA(2) genes that mediate nodulation reactions strongly supports our hypothesis that sPLA(2)s are central enzymes in insect cellular immune reactions...
  29. Kwun I, Cho Y, Lomeda R, Shin H, Choi J, Kang Y, et al. Zinc deficiency suppresses matrix mineralization and retards osteogenesis transiently with catch-up possibly through Runx 2 modulation. Bone. 2010;46:732-41 pubmed publisher
    ..Decreased and delayed bone marker gene, Runx2 expression and ECM mineralization in osteoblasts by zinc deficiency can be a potential explanation for the retarded skeletal growth which is the major zinc deficiency syndrome. ..
  30. Park B, Kim Y. Exogenous JH and ecdysteroid applications alter initiation of polydnaviral replication in an endoparasitoid wasp, Cotesia plutellae (Braconidae: Hymenoptera). BMB Rep. 2011;44:393-8 pubmed publisher
    ..Although RH5992 had no effect dose on adult development, it significantly accelerated viral replication. The results of immunoblotting assays against viral coat proteins support the effects of the hormone agonists on viral replication. ..
  31. Park Y, Kim Y. RNA interference of cadherin gene expression in Spodoptera exigua reveals its significance as a specific Bt target. J Invertebr Pathol. 2013;114:285-91 pubmed publisher
    ..thuringiensis ssp. kurstaki. These results suggest that SeCad1 is a specific target molecule to Cry1C toxin from B. thuringiensis in S. exigua, but not to Cry1A toxin...
  32. Park J, Stanley D, Kim Y. Rac1 mediates cytokine-stimulated hemocyte spreading via prostaglandin biosynthesis in the beet armyworm, Spodoptera exigua. J Insect Physiol. 2013;59:682-9 pubmed publisher
    ..We infer that SeRac1 transduces OA, 5-HT, and PSP signaling via activating biosynthesis of prostaglandins and possibly other eicosanoids...
  33. Ramjan Ali M, Kim Y. A novel polydnaviral gene family, BEN, and its immunosuppressive function in larvae of Plutella xylostella parasitized by Cotesia plutellae. J Invertebr Pathol. 2012;110:389-97 pubmed publisher
    ..plutellae and play crucial role in inducing immunosuppression. Homologous BEN family genes were found in other bracoviral genomes. We propose BEN domain-containing genes as a new functional gene family in polydnaviruses. ..
  34. Park J, Kim Y. Eicosanoid biosynthesis is activated via Toll, but not Imd signal pathway in response to fungal infection. J Invertebr Pathol. 2012;110:382-8 pubmed publisher
    ..These results suggest that eicosanoid biosynthesis is activated via Toll, but not Imd signal pathway in response to fungal infection in S. exigua. ..
  35. Seo S, Lee S, Hong Y, Kim Y. Phospholipase A2 inhibitors synthesized by two entomopathogenic bacteria, Xenorhabdus nematophila and Photorhabdus temperata subsp. temperata. Appl Environ Microbiol. 2012;78:3816-23 pubmed publisher
    ..This study reports bacterial-origin PLA(2) inhibitors, which would be applicable for developing novel insecticides. ..
  36. Alcantara E, Shin M, Sohn H, Park Y, Kim T, Lim J, et al. Diosgenin stimulates osteogenic activity by increasing bone matrix protein synthesis and bone-specific transcription factor Runx2 in osteoblastic MC3T3-E1 cells. J Nutr Biochem. 2011;22:1055-63 pubmed publisher
    ..The increased levels of these marker proteins, in turn, can increase the formation of calcium deposits within the ECM thereby increasing bone formation...
  37. Lee S, Nalini M, Kim Y. A viral lectin encoded in Cotesia plutellae bracovirus and its immunosuppressive effect on host hemocytes. Comp Biochem Physiol A Mol Integr Physiol. 2008;149:351-61 pubmed publisher
    ..These results support an existence of a polydnaviral lectin family among Cotesia-associated bracovirus and propose its immunosuppressive function. ..
  38. Kim G, Nalini M, Kim Y, Lee D. Octopamine and 5-hydroxytryptamine mediate hemocytic phagocytosis and nodule formation via eicosanoids in the beet armyworm, Spodoptera exigua. Arch Insect Biochem Physiol. 2009;70:162-76 pubmed publisher
    ..Taken together, this study suggests that octopamine and 5-HT can mediate hemocytic phagocytosis and nodule formation through a downstream signal pathway relayed by eicosanoids in S. exigua...
  39. Shrestha S, Kim Y. Biochemical characteristics of immune-associated phospholipase A(2) and its inhibition by an entomopathogenic bacterium, Xenorhabdus nematophila. J Microbiol. 2009;47:774-82 pubmed publisher
    ..Effect of a PLA(2)-inhibitory fraction on the immunosuppression of T. castaneum was equally comparable with that resulted from inhibition of the TcPLA(2) gene expression by RNA interference. ..
  40. Jeong J, Ju S, Park J, Lee J, Yun K, Kwon S, et al. Antioxidant activity in essential oils of Cnidium officinale makino and Ligusticum chuanxiong Hort and their inhibitory effects on DNA damage and apoptosis induced by ultraviolet B in mammalian cell. Cancer Epidemiol. 2009;33:41-6 pubmed publisher
    ..These results suggest that essential oils in C. officinale and L. chuanxiong may exert inhibitory effects on DNA damage and apoptosis induced by UVB through their high free radical scavenging ability. ..
  41. Kim Y. Identification of host translation inhibitory factor of Campoletis sonorensis ichnovirus on the tobacco budworm, Heliothis virescens. Arch Insect Biochem Physiol. 2005;59:230-44 pubmed
    ..virescens. These results indicate that both cys-motif proteins of VHv 1.4 and VHv 1.1 play a role as HTIF in C. sonorensis parasitization...
  42. Shrestha S, Kim Y. An entomopathogenic bacterium, Xenorhabdus nematophila, inhibits hemocyte phagocytosis of Spodoptera exigua by inhibiting phospholipase A(2). J Invertebr Pathol. 2007;96:64-70 pubmed
    ..nematophila, inhibited phagocytosis in a dose-dependent manner. These results suggest that X. nematophila produces and secretes PLA(2) inhibitor(s), which in turn inhibit the phagocytic response of hemocytes...
  43. Vatanparast M, Kim Y. Optimization of recombinant bacteria expressing dsRNA to enhance insecticidal activity against a lepidopteran insect, Spodoptera exigua. PLoS ONE. 2017;12:e0183054 pubmed publisher
    ..Moreover, targeting young larvae possessing weak RNase activity in the midgut lumen significantly enhanced RNAi efficiency and subsequent insecticidal activity against S. exigua. ..