Experts and Doctors on humans in Seoul, South Korea


Locale: Seoul, South Korea
Topic: humans

Top Publications

  1. Lee E, Lee Y, Suh D, Kang J, Kim I. Detection of HER-2 and EGFR gene amplification using chromogenic in-situ hybridization technique in ovarian tumors. Appl Immunohistochem Mol Morphol. 2010;18:69-74 pubmed publisher
  2. Kwon Y, Ha J, Paik D, Jin B, Bae K. The relationship between periodontitis and metabolic syndrome among a Korean nationally representative sample of adults. J Clin Periodontol. 2011;38:781-6 pubmed publisher
    ..32-1.83) for MS. In subgroup analysis, periodontitis is associated with MS in subjects over age 40 and the adjusted ORs were higher in females and in the smoker group than in males and in non-smokers. MS is associated with periodontitis. ..
  3. Rim H, Min K, Lee H, Jeong S, Lee S. pH-Tunable calcium phosphate covered mesoporous silica nanocontainers for intracellular controlled release of guest drugs. Angew Chem Int Ed Engl. 2011;50:8853-7 pubmed publisher
  4. Ku J, Kang S, Shin Y, Kang H, Hong S, Kim I, et al. Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines. Oncogene. 2004;23:6736-42 pubmed
  5. Jeong H, Cho D, Ahn K, Jin D. Complications of tracheotomy in patients with mucopolysaccharidoses type II (Hunter syndrome). Int J Pediatr Otorhinolaryngol. 2006;70:1765-9 pubmed
    ..To investigate the complication rate of tracheotomy in patients with mucopolysacchridoses (MPS) type II (Hunter syndrome)...
  6. Kim M, Cho K, Kwon G, Park S, Kim Y, Kim J, et al. ERCC1 predicting chemoradiation resistance and poor outcome in oesophageal cancer. Eur J Cancer. 2008;44:54-60 pubmed
    ..Patients with ERCC1-negative tumours showed tendencies toward prolonged overall survival (p=0.10) and event free survival (p=0.08). Prospective studies are required to determine the benefit of preoperative CRT in ERCC1-negative tumours. ..
  7. Kim D, Ahn S, Lee H, Kim S, Kim J, Paik Y, et al. Anti-hepatitis A virus seroprevalence among patients with chronic viral liver disease in Korea. Eur J Gastroenterol Hepatol. 2007;19:923-6 pubmed
    ..2, 97.4, 100 and 98.8%, respectively, showing marked increase in those over 40 years of age (P<0.001). Our study demonstrates that most Korean patients over 40 years of age with chronic liver disease have already been exposed to HAV. ..
  8. Jung S, Yang W, Kim J, Kim H, Kim E, Yun H, et al. Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells. Carcinogenesis. 2008;29:713-21 pubmed publisher
    ..Collectively, our findings identify AMPK as a key determinant of HIF-1 functions in response to ROS and its possible role in the sophisticated HIF-1 regulatory mechanisms. ..
  9. Seo J, Park J, Kim H, Ki H, Park J, Park M, et al. Korean medical libraries and professional associations: changing services and roles. Health Info Libr J. 2008;25:142-9 pubmed publisher

More Information

Publications1047 found, 100 shown here

  1. Jeong E, Kim M, Nam H, Min C, Lee S, Chung Y, et al. Somatic mutations of JAK1 and JAK3 in acute leukemias and solid cancers. Clin Cancer Res. 2008;14:3716-21 pubmed publisher
    ..The data suggest that some of the JAK1 and JAK3 mutations may to be functional and contributes to cancer development, especially to T-ALL development. ..
  2. Lee K, Yoon J, Min W, Lim H, Song J, Chae S, et al. Standardization of terminology in laboratory medicine II. J Korean Med Sci. 2008;23:711-3 pubmed publisher
    ..We herein described the Korean standard laboratory terminology database for test names, result description terms, and result units encompassing most of the laboratory tests in Korea. ..
  3. Yoon H, Chin H, Na K, Chae D, Kim S, Jeon U, et al. Association of angiotensin II type 2 receptor gene A1818T polymorphism with progression of immunoglobulin A nephropathy in Korean patients. J Korean Med Sci. 2009;24 Suppl:S38-43 pubmed publisher
    ..221 (95% confidence interval for Exp(B): 0.052-0.940, p=0.041) compared to that of without T allele. In conclusion, A1818T polymorphism of AT2R gene was associated with the progression of IgAN. ..
  4. Hong S, Oh K, Cho S, Kim J, Park M, Lim H, et al. Asymptomatic healthy slaughterhouse workers in South Korea carrying Shiga toxin-producing Escherichia coli. FEMS Immunol Med Microbiol. 2009;56:41-7 pubmed publisher
    ..Eight Vero cell cytotoxicity assay-positive strains were isolated from the workers and these workers were asymptomatic and healthy. The results of the study show that slaughter plant workers are at high risk of STEC infection. ..
  5. Lee J, Lee S, Kim Y, Jeong C. Protective effects of neohesperidin and poncirin isolated from the fruits of Poncirus trifoliata on potential gastric disease. Phytother Res. 2009;23:1748-53 pubmed publisher
    ..From these results, it could be suggested that neohesperidin and poncirin isolated from PF may be useful for the treatment and/or protection of gastritis...
  6. Jeong Y, Lee J, Kim S, Yun H, Baek K, Kwon N, et al. Enhanced effects of citrate on UVB-induced apoptosis of B16 melanoma cells. Pharmazie. 2009;64:829-33 pubmed
    ..From these results, we suggest that citrate might reduce the risk of developing melanoma induced by UVB...
  7. Lee S, Chun Y, Kim J, Kim E, Kim J. The relationship between demodex and ocular discomfort. Invest Ophthalmol Vis Sci. 2010;51:2906-11 pubmed publisher
    ..To determine the correlative relationship between the prevalence of Demodex in eyelashes and the severity of ocular discomfort, by investigating the demographic epidemiology associated with Demodex...
  8. Song J, Choi H, Jung I, Jung H, Kim S. The prevalence and morphologic classification of distolingual roots in the mandibular molars in a Korean population. J Endod. 2010;36:653-7 pubmed publisher
    ..5% and 1.4%, respectively). Data regarding the pattern of occurrence and the morphologic features of DL roots can provide useful information to clinicians, leading to higher rate of success of endodontic treatment. ..
  9. Ahn D, Park H, Choi D, Kim K, Yang S. Survival and prognostic analysis of adjacent segments after spinal fusion. Clin Orthop Surg. 2010;2:140-7 pubmed publisher
  10. Park D, Lee S, Lee T, Ryu C, Kim H, Seo D, et al. Anchoring flap versus flared end, fully covered self-expandable metal stents to prevent migration in patients with benign biliary strictures: a multicenter, prospective, comparative pilot study (with videos). Gastrointest Endosc. 2011;73:64-70 pubmed publisher
    ..However, the major limitations of FCSEMSs are frequent migration and removal complications...
  11. Kim H, Lee S, Kang C, Ryu J, Shin M, Cho K, et al. Evaluation of the chondromalacia patella using a microscopy coil: comparison of the two-dimensional fast spin echo techniques and the three-dimensional fast field echo techniques. Korean J Radiol. 2011;12:78-88 pubmed publisher
    ..We wanted to compare the two-dimensional (2D) fast spin echo (FSE) techniques and the three-dimensional (3D) fast field echo techniques for the evaluation of the chondromalacia patella using a microscopy coil...
  12. Lee K, Kim W, Kim E, Lee J. Is swallowing of all mixed consistencies dangerous for penetration-aspiration?. Am J Phys Med Rehabil. 2012;91:187-92 pubmed publisher
    ..The risk of penetration-aspiration may be judged depending on not only a food's consistency but also on various factors that affect airway protection, including the texture of food. ..
  13. Choi J, Yang J, Bang D, Park J, Suh J, Huh Y, et al. Targetable gold nanorods for epithelial cancer therapy guided by near-IR absorption imaging. Small. 2012;8:746-53 pubmed publisher
    ..CET-PGNRs exhibit excellent tumor targeting ability and strong potential for simultaneous absorption imaging and photothermal ablation of epithelial cancer cells. ..
  14. Kang J, Kim N, Shin C, Lee H, Lee D, Jung H, et al. Predictive factors for improvement of atrophic gastritis and intestinal metaplasia after Helicobacter pylori eradication: a three-year follow-up study in Korea. Helicobacter. 2012;17:86-95 pubmed publisher
    ..This study was performed to investigate whether eradication of H. pylori could lead to the improvement of AG and IM, and the prognostic factors associated with the improvement of AG and IM...
  15. Yun Y, Kim Y, Min Y, Park S, Won Y, Kim D, et al. The influence of hospital volume and surgical treatment delay on long-term survival after cancer surgery. Ann Oncol. 2012;23:2731-7 pubmed
    ..78-3.81). Our findings suggest that the effect of hospital volume and surgical treatment delay on overall survival of cancer patients should be considered in formulating or revising national health policy. ..
  16. Kim J, Song M, Kang G, Lee E, Choi H, Lee C, et al. Combined treatment of 3-hydroxyflavone and imatinib mesylate increases apoptotic cell death of imatinib mesylate-resistant leukemia cells. Leuk Res. 2012;36:1157-64 pubmed publisher
    ..Our results suggest that this combined treatment is beneficial in imatinib mesylate-resistant chronic myelogenous leukemia...
  17. Moon J, Kuh S, Park H, Kim K, Park J, Chin D, et al. Triamcinolone decreases bupivacaine toxicity to intervertebral disc cell in vitro. Spine J. 2012;12:665-73 pubmed publisher
    ..Considering the frequent use of these agents in spinal interventions, it is meaningful to know how they affect intervertebral disc cells...
  18. Kim J, Jung Y, Bong Y, Lee K, Hwang G. Determination of the geographical origin of kimchi by (1)H NMR-based metabolite profiling. Biosci Biotechnol Biochem. 2012;76:1752-7 pubmed
    ..These results establish biochemical profiles for kimchi extracts, and indicate that metabolomics can be used in the discrimination of food origins. ..
  19. Lee T, Jang J, Kang S, Jin M, Shin H, Kim D, et al. Enhancement of osteogenic and chondrogenic differentiation of human embryonic stem cells by mesodermal lineage induction with BMP-4 and FGF2 treatment. Biochem Biophys Res Commun. 2013;430:793-7 pubmed publisher
    ..This method could be useful to enhance the osteogenic or chondrogenic differentiation of hESCs. ..
  20. Song J. Advances in pneumococcal antibiotic resistance. Expert Rev Respir Med. 2013;7:491-8 pubmed publisher
    ..Widespread use of PCV13, which covers additional serotypes 3, 6A and 19A, may contribute to reduce the clonal spread of drug-resistant 19A pneumococci. ..
  21. Ryu S, Huh I, Cho E, Cho Y, Park T, Yoon S, et al. Association Study of 60 Candidate Genes with Antipsychotic-induced Weight Gain in Schizophrenia Patients. Pharmacopsychiatry. 2016;49:51-6 pubmed publisher
    ..Our findings suggested the involvement of a GHRL polymorphism in weight gain, which was specifically mediated by appetite change, during antipsychotic treatment in schizophrenia patients. ..
  22. Lee J, Roh J, Lee S, Park Y, Cho K, Choi S, et al. Overexpression of glutathione peroxidase 1 predicts poor prognosis in oral squamous cell carcinoma. J Cancer Res Clin Oncol. 2017;143:2257-2265 pubmed publisher
    ..05), while increased GPX4 or TrxR1 expression was not (all P > 0.1). Tumour GPX1 expression is a useful biomarker predictive of recurrence and survival in OSCC patients. ..
  23. Kim M, Pai C, Woo J, Ryu J, Hiramatsu K. Vancomycin-intermediate Staphylococcus aureus in Korea. J Clin Microbiol. 2000;38:3879-81 pubmed
    ..The blood culture isolate of MRSA exhibited reduced susceptibility to vancomycin (MIC, 8 microg/ml). This is the first report of a vancomycin-intermediate S. aureus case from Korea. ..
  24. Rah D, Kim S, Lee K, Park B, Kim D. Objective evaluation of treatment effects on port-wine stains using L*a*b* color coordinates. Plast Reconstr Surg. 2001;108:842-7 pubmed
    ..The color analysis system proposed as a result of this study is very easy, objective, quantitative, cost-effective, and can be useful for the evaluation of treatment effects on colored skin lesions such as port-wine stains. ..
  25. Yun Choi H, Pyo M, Park K, Chang K, Lee D. Anti-thrombotic effects of higenamine. Planta Med. 2001;67:619-22 pubmed
    ..The oral administration of higenamine (50 or 100 mg/kg) increased the recovery rates from the acute thrombotic challenge in mice and lowered the weight of thrombus formed inside the AV-shunt tube in rats. ..
  26. Kim J, Kim W, Choi C, Choi S, Jeon T, Kim T, et al. [A case of Crohn's disease with iliac arterio-enteric fistulae]. Korean J Gastroenterol. 2003;42:77-80 pubmed
    ..Emergent operation confirmed iliac arterioenteric fistulae with active bleeding, There was no further intestinal bleeding after surgery. Remission had been maintained for 3 years with mesalazine. ..
  27. Ho J, Lee Y, Park J, Jun W, Kim H, Hong B, et al. Protective effects of aucubin isolated from Eucommia ulmoides against UVB-induced oxidative stress in human skin fibroblasts. Biol Pharm Bull. 2005;28:1244-8 pubmed
    ..An understanding of the antioxidant properties of aucubin could, in part, act to elucidate its protective mechanism on the human skin photoaging. ..
  28. Hahn J. Regulation of Nod1 by Hsp90 chaperone complex. FEBS Lett. 2005;579:4513-9 pubmed
    ..These findings suggest a common regulatory mechanism involving the Hsp90 chaperone complex in R-mediated disease resistance in plants and Nod1-mediated innate immune response in mammals. ..
  29. Jun D, Moon J, Baeg S, Choi H, Sohn J, Lee O, et al. [A clinical study of pyogenic liver abscess at two different local hospitals]. Korean J Hepatol. 2005;11:250-60 pubmed
    ..Diabetes and biliary tract disease, including, previous hepatobiliary surgery, were the most identifiable underlying disease. ..
  30. Lee H, Han S, Kang J, Lee M, Choi J, Moon K, et al. Multiple mucinous and lipomatous variant of eccrine angiomatous hamartoma associated with spindle cell hemangioma: a novel collision tumor?. J Cutan Pathol. 2006;33:323-6 pubmed
    ..To our knowledge, the co-existence of EAH with SCH is a novel finding and not yet described...
  31. Cho W, Lee Y, Kong S, Hurwitz J, Lee J. CDC7 kinase phosphorylates serine residues adjacent to acidic amino acids in the minichromosome maintenance 2 protein. Proc Natl Acad Sci U S A. 2006;103:11521-6 pubmed
    ..This finding may explain why the sequential action of cyclin-dependent and Cdc7 kinases is essential for the initiation of DNA replication. ..
  32. Lee Y, Rho Y, Choi S, Ji J, Song G. Association of TNF-alpha -308 G/A polymorphism with responsiveness to TNF-alpha-blockers in rheumatoid arthritis: a meta-analysis. Rheumatol Int. 2006;27:157-61 pubmed
  33. Kim H, Conklin J, Park H. The effect of sildenafil on segmental oesophageal motility and gastro-oesophageal reflux. Aliment Pharmacol Ther. 2006;24:1029-36 pubmed
    ..Sildenafil did not alter the reflux. Sildenafil alters lower oesophageal sphincter function and oesophageal bolus transit, but not induce gastro-oesophageal reflux. ..
  34. Park J, Jung Y, Kim J, Kim K, Ahn S, Song K, et al. TC1 (C8orf4) is upregulated by cellular stress and mediates heat shock response. Biochem Biophys Res Commun. 2007;360:447-52 pubmed
    ..Heat shock factor 1(HSF1) and TC1 upregulate each other, suggesting a potential positive feedback in the heat shock response regulation. Our data suggest that TC1 is a novel heat shock response regulator. ..
  35. Yune T, Lee J, Jiang M, Kim D, Choi S, Oh T. Systemic administration of PEP-1-SOD1 fusion protein improves functional recovery by inhibition of neuronal cell death after spinal cord injury. Free Radic Biol Med. 2008;45:1190-200 pubmed publisher
    ..These results suggest that PEP-1-SOD1 may provide a novel strategy for the therapeutic delivery of antioxidant enzymes that protect neurons from ROS after SCI. ..
  36. Kim S, Lee S, Choi Y, Wang L, Park C, Shin Y. Extensive alteration in the expression profiles of TGFB pathway signaling components and TP53 is observed along the gastric dysplasia-carcinoma sequence. Histol Histopathol. 2008;23:1439-52 pubmed publisher
    ..The extensive change in expression of TGFB signaling components is implicated during tumorigenesis of gastric neoplasias. ..
  37. Choi J, Yun J, Kim Y, Lee E, Hwang S, Cho Y, et al. Pre-operative predictive factors for gallbladder cholesterol polyps using conventional diagnostic imaging. World J Gastroenterol. 2008;14:6831-4 pubmed
    ..In addition, US and the CT scan had low accuracy in predicting the polyp diameter compared to that determined by postoperative pathology. ..
  38. Sung K, Lee S, Park S, Choi J, Kim S, Yun S, et al. Twenty-four hour ocular perfusion pressure fluctuation and risk of normal-tension glaucoma progression. Invest Ophthalmol Vis Sci. 2009;50:5266-74 pubmed publisher
    ..Clinical factors other than IOP were associated with VF progression in our series of medically treated NTG eyes. Twenty-four-hour MOPP fluctuation was the most consistent prognostic factor for glaucoma progression. ..
  39. Jeong S, Song W, Kim J, Kim H, Lee K. Broth microdilution method to detect extended-spectrum beta-lactamases and AmpC beta-lactamases in enterobacteriaceae isolates by use of clavulanic acid and boronic acid as inhibitors. J Clin Microbiol. 2009;47:3409-12 pubmed publisher
    ..The BMD testing could be applicable for routine use in commercially available semiautomated systems for the detection of ESBLs and PABLs in Enterobacteriaceae. ..
  40. Jee S, Golub J, Jo J, Park I, Ohrr H, Samet J. Smoking and risk of tuberculosis incidence, mortality, and recurrence in South Korean men and women. Am J Epidemiol. 2009;170:1478-85 pubmed publisher
    ..5, 95% CI: 1.3, 1.7). This study provides longitudinal evidence that smoking increases risk of incident tuberculosis, mortality from tuberculosis, and tuberculosis recurrence. ..
  41. Hong S, Oh J, Jung Y, Kim Y, Kim S, Kang S, et al. DNA methylation patterns of ulcer-healing genes associated with the normal gastric mucosa of gastric cancers. J Korean Med Sci. 2010;25:405-17 pubmed publisher
    ..6). These results suggest that the combined methylation pattern of ulcer-healing genes serves as a sensitive marker for predicting cancer-prone gastric mucosa. ..
  42. Lim S, Kim H, Jung G. p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma. FEBS Lett. 2010;584:2231-6 pubmed publisher
    ..These findings contribute to a better understanding of the role of p53 mutation and Snail overexpression as a late event in hepatocarcinogenesis. ..
  43. Park C, Lee M, Kim H, Lee G, Park J, Cinn Y. Congenital zinc deficiency from mutations of the SLC39A4 gene as the genetic background of acrodermatitis enteropathica. J Korean Med Sci. 2010;25:1818-20 pubmed publisher
    ..1287+2T>C). Family study showed that his parents were heterozygous carriers of the mutations. To the best of our knowledge, this is the first report of genetically confirmed AE in Korea. ..
  44. Kwon D, Park M, Park J, Cho S, Park C, Oh J, et al. Characterization of a putative cis-regulatory element that controls transcriptional activity of the pig uroplakin II gene promoter. Biochem Biophys Res Commun. 2011;410:264-9 pubmed publisher
    ..Thus, the binding element and its binding protein, HNF4 transcription factor, may be involved in the mechanism that specifically regulates pUPII gene transcription. ..
  45. Park S, Park Y, Lee S, Jeong M, Yu K, Jung H, et al. Comparing the toxic mechanism of synthesized zinc oxide nanomaterials by physicochemical characterization and reactive oxygen species properties. Toxicol Lett. 2011;207:197-203 pubmed publisher
  46. Lee S, Kang K, Shin S, Herr Y, Lee Y, Kim E. Endoplasmic reticulum stress modulates nicotine-induced extracellular matrix degradation in human periodontal ligament cells. J Periodontal Res. 2012;47:299-308 pubmed publisher
    ..These results indicate that nicotine-induced cell death is mediated by the ER stress pathway, involving ECM degradation by MMPs, in human periodontal ligament cells. ..
  47. Koo J, Kim M, Kim E, Park B. Comparison of immunohistochemical staining in breast papillary neoplasms of cytokeratin 5/6 and p63 in core needle biopsies and surgical excisions. Appl Immunohistochem Mol Morphol. 2012;20:108-15 pubmed
  48. Wi H, Jin Y, Choi M, Hong S, Bae Y. Predominance of IL-10 and TGF-? production from the mouse macrophage cell line, RAW264.7, in response to crude antigens from Clonorchis sinensis. Cytokine. 2012;59:237-44 pubmed publisher
    ..Taken together, these data demonstrate that CA from C. sinensis may modulate host immune responses by upregulating anti-inflammatory cytokines via the regulation of ERK. ..
  49. Kim I, Piao S, Lee J, Hong S, Hwang T, Kim S, et al. Effect of an adipose-derived stem cell and nerve growth factor-incorporated hydrogel on recovery of erectile function in a rat model of cavernous nerve injury. Tissue Eng Part A. 2013;19:14-23 pubmed publisher
    ..This study suggests that application of hADSCs with NGF-hydrogel on the CN might be a promising treatment for postprostatectomy ED. ..
  50. Kang M, Lee K, Jang J, Han I, Kim S. Evaluation of clinical meaning of histological subtypes of intraductal papillary mucinous neoplasm of the pancreas. Pancreas. 2013;42:959-66 pubmed publisher
    ..050), which lost statistical significance after multivariate analysis (P = 0.341). Although histological subtypes are associated with the degree of dysplasia, histological subtypes have limited prognostic value for pancreatic IPMNs. ..
  51. Koh Y, Lee H, Ahn J, Lee J, Gong G. Expression of Lewis X is associated with poor prognosis in triple-negative breast cancer. Am J Clin Pathol. 2013;139:746-53 pubmed publisher
    ..001 and P < .001, respectively). Our results suggest that Le(X) expression is an independent prognostic factor for RFS and OS in younger patients with TNBC. ..
  52. Byun B, Kong C, Park J, Seo Y, Lim I, Choi C, et al. Initial metabolic tumor volume measured by 18F-FDG PET/CT can predict the outcome of osteosarcoma of the extremities. J Nucl Med. 2013;54:1725-32 pubmed publisher
    ..We evaluated the ability of metabolic and volumetric parameters measured by pretreatment (18)F-FDG PET/CT to predict the survival of patients with osteosarcoma of the extremities...
  53. Song N, Chung M, Kang N, Seo S, Jang T, Lee H, et al. Quercetin suppresses invasion and migration of H-Ras-transformed MCF10A human epithelial cells by inhibiting phosphatidylinositol 3-kinase. Food Chem. 2014;142:66-71 pubmed publisher
    ..Collectively, these results suggest that PI3K is a molecular target of quercetin for the inhibition of H-Ras-induced invasion and migration of MCF10A cells. ..
  54. Heo J, Kim S, Kim B, Park J, Kim D, Ahn S, et al. Use of Wisteria Floribunda Agglutinin-Positive Human Mac-2 Binding Protein in Assessing Risk of Hepatocellular Carcinoma Due to Hepatitis B Virus. Medicine (Baltimore). 2016;95:e3328 pubmed
    ..low) levels of WFA-M2BP (log-rank test, P?=?0.016).WFA-M2BP determination significantly reflected degree/extent of hepatic fibrosis and independently predicted the risk of developing HCC in patients with CHB. ..
  55. Choi J, Goo J, Chung M, Kim H, Im J. Angiolipoma of the posterior mediastinum with extension into the spinal canal: a case report. Korean J Radiol. 2000;1:212-4 pubmed
    ..We report a case of posterior mediastinal angiolipoma extending into the spinal canal and showing both fat and angiomatous features on CT scan. ..
  56. Lee K, Park Y, Yu H, Choi S, Yoo Y. Effects of continuous and interrupted orthodontic force on interleukin-1beta and prostaglandin E2 production in gingival crevicular fluid. Am J Orthod Dentofacial Orthop. 2004;125:168-77 pubmed
    ..In addition, the analysis of crevicular fluid is a useful method for assessing cellular response to orthodontic force in vivo. ..
  57. Lee K, Jung H, Park H, Kim D, Lee J, Lee K. Beta-D-xylopyranosyl-(1-->3)-beta-D-glucuronopyranosyl echinocystic acid isolated from the roots of Codonopsis lanceolata induces caspase-dependent apoptosis in human acute promyelocytic leukemia HL-60 cells. Biol Pharm Bull. 2005;28:854-9 pubmed
  58. Park H, Kim Y, Leem K, Park S, Seo J, Kim H, et al. Coptis japonica root extract induces apoptosis through caspase3 activation in SNU-668 human gastric cancer cells. Phytother Res. 2005;19:189-92 pubmed
    ..These results suggest that Coptis japonica could induce apoptotic anticancer effect through caspase3 activation on SNU-668 human gastric cancer cells. ..
  59. Choi J, Hwang Y, Choi Y, Yoo K, Kim J, Nam S, et al. Neuronal apoptosis inhibitory protein is overexpressed in patients with unfavorable prognostic factors in breast cancer. J Korean Med Sci. 2007;22 Suppl:S17-23 pubmed
    ..In conclusion, NAIP is overexpressed in breast cancer patients with unfavorable clinical features such as stage and tumor size, suggesting that NAIP would play a role in the disease manifestation. ..
  60. Jang Y, Lee S, Lim J, Lee H, Kim T, Park J, et al. The rate of Salmonella spp. infection in zoo animals at Seoul Grand Park, Korea. J Vet Sci. 2008;9:177-81 pubmed
    ..In addition, prevention of human infection requires proper education about personal hygiene...
  61. Li S, Shin D, Chun Y, Lee M, Kim M, Park J. A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1{alpha}. Mol Cancer Ther. 2008;7:3729-38 pubmed publisher
    ..Given these results, we suggest that the functional inactivation of HIF-alpha contributes to the YC-1-induced deregulation of hypoxia-induced genes. ..
  62. Kim Y, Choi Y, Kim J. Simultaneous bilateral sequential total knee replacement is as safe as unilateral total knee replacement. J Bone Joint Surg Br. 2009;91:64-8 pubmed publisher
    ..143). Simultaneous bilateral sequential TKR can be offered to patients at low and high risk and has an expected rate of complications similar to that of unilateral TKR. ..
  63. Kim K, Shin J, Song H, Ko G, Kim J, Yoon H, et al. Palliative treatment of malignant esophagopulmonary fistulas with covered expandable metallic stents. AJR Am J Roentgenol. 2009;193:W278-82 pubmed publisher
    ..The objective of our study was to evaluate the safety and clinical effectiveness of covered expandable metallic stents for palliative treatment of malignant esophagopulmonary fistulas...
  64. Lee N, Yun S, Chae S, Yoo B, Cha S, Kwak B. Perforated duodenal ulcer presenting with massive hematochezia in a 30-month-old child. World J Gastroenterol. 2009;15:4853-5 pubmed
    ..Finally, an exploratory laparotomy was performed. A discrete anterior perforation with active bleeding of the duodenal wall was found. After the operation, there were no complications and the patient recovered fully. ..
  65. Kim J, Kim H, Moon D, Jung S, Choo S, Chung C, et al. Long-term outcomes after surgery for rheumatic mitral valve disease: valve repair versus mechanical valve replacement. Eur J Cardiothorac Surg. 2010;37:1039-46 pubmed publisher
    ..Both MV repair and replacement had comparable long-term clinical results; therefore, repair surgery seems to be more beneficial by avoiding troublesome life-long anticoagulation and risks of bleeding. ..
  66. Hong J, Suh S, Modi H, Hur C, Song H, Park J. Reliability analysis for radiographic measures of lumbar lordosis in adult scoliosis: a case-control study comparing 6 methods. Eur Spine J. 2010;19:1551-7 pubmed publisher
    ..And the TRALL method is more reliable method than other methods which include the L5-S1 joint in lordosis measurement...
  67. Lee K, Lee N. Comparison of clinical characteristics between primary and secondary paranasal mucoceles. Yonsei Med J. 2010;51:735-9 pubmed publisher
  68. Kim E, Yeh D, Choe Y, Lee W, Lim H. Image quality and attenuation values of multidetector CT coronary angiography using high iodine-concentration contrast material: a comparison of the use of iopromide 370 and iomeprol 400. Acta Radiol. 2010;51:982-9 pubmed publisher
    ..With standardization for an iodine flux, the attenuation is significantly higher when using iopromide 370. ..
  69. Park S, Lee C, Kwak Y, Moon C, Kim B, Kim E, et al. Antigenic drift of Orientia tsutsugamushi in South Korea as identified by the sequence analysis of a 56-kDa protein-encoding gene. Am J Trop Med Hyg. 2010;83:930-5 pubmed publisher
    ..1%). This antigenic drift had a negative effect on the PHA results. Periodic surveillance of the contemporary strains using sequence analysis is needed...
  70. Kim D, Cho E, Moon M, Park S, Hwang J, Kah O, et al. Revisiting the evolution of gonadotropin-releasing hormones and their receptors in vertebrates: secrets hidden in genomes. Gen Comp Endocrinol. 2011;170:68-78 pubmed publisher
    ..In this article, we focus only on vertebrate genomes because of the difficulty in comparing invertebrate and vertebrate genomes due to their marked divergence. ..
  71. Kim J, Han M, Hanl K, Kim H. Vitamin E inhibition on platelet procoagulant activity: involvement of aminophospholipid translocase activity. Thromb Res. 2011;127:435-42 pubmed publisher
    ..These actions of vitamin E on platelet function provide new insights into the anticoagulation properties of vitamin E. ..
  72. Jeung H, Rha S, Im C, Shin S, Ahn J, Yang W, et al. A randomized phase 2 study of docetaxel and S-1 versus docetaxel and cisplatin in advanced gastric cancer with an evaluation of SPARC expression for personalized therapy. Cancer. 2011;117:2050-7 pubmed publisher
    ..The findings suggest that split-dose weekly docetaxel alleviates hematological toxicity without compromising efficacy, and that SPARC expression may help individualize therapy in advanced gastric cancer. ..
  73. Ok S, Kim S, Kim C, Nam D, Shim B, Kim S, et al. Emodin inhibits invasion and migration of prostate and lung cancer cells by downregulating the expression of chemokine receptor CXCR4. Immunopharmacol Immunotoxicol. 2012;34:768-78 pubmed publisher
    ..Overall, our findings suggest that ED is a novel blocker of CXCR4 expression and, thus, has enormous potential as a powerful therapeutic agent for metastatic cancer. ..
  74. Jung S, Kim K, Tae K, Kong G, Kim M. The effect of raw vegetable and fruit intake on thyroid cancer risk among women: a case-control study in South Korea. Br J Nutr. 2013;109:118-28 pubmed publisher
    ..These results suggest that high consumption of raw vegetables, persimmons and tangerines may decrease thyroid cancer risk and help prevent early-stage thyroid cancer. ..
  75. Han K, Ahn D, Lee S, Min Y, Kwon A, Ahn H, et al. Identification of chromosomal HP0892-HP0893 toxin-antitoxin proteins in Helicobacter pylori and structural elucidation of their protein-protein interaction. J Biol Chem. 2013;288:6004-13 pubmed publisher
    ..Therefore, it is highly probable that TA systems of H. pylori are involved in virulence of H. pylori...
  76. Seo Y, Shin Y, Kim H, Kang I, Hong I, Choi S, et al. Donepezil enhances Purkinje cell survival and alleviates motor dysfunction by inhibiting cholesterol synthesis in a murine model of Niemann Pick disease type C. J Neuropathol Exp Neurol. 2014;73:234-43 pubmed publisher
    ..Taken together, our findings suggest the role of a cholinergic pathway as a novel regulator of NPC progression and the potential application of AChEIs for the treatment of human NPC. ..
  77. Choi B, Oh H, Lee Y, Song Y. Prevalence and clinical impact of fibromyalgia in patients with primary Sjögren's syndrome. Clin Exp Rheumatol. 2016;34:S9-13 pubmed
    ..0072) decreased compared to those without FM. Our study showed that FM was prevalent in pSS. FM was associated with higher ESSPRI and more severe depression. ..
  78. Kim W, Chun Y, Cho B, Lee J. Biometric and refractive changes after orbital decompression in Korean patients with thyroid-associated orbitopathy. Eye (Lond). 2016;30:400-5 pubmed publisher
    ..TAO patients who underwent orbital decompression showed myopic refractive change via increase in AL. Possible refractive changes should be considered in cases of TAO complaining of decreased visual acuity after orbital decompression. ..
  79. Kim J, Lee J, Chung J, Shin Y. Locally adaptive 2D-3D registration using vascular structure model for liver catheterization. Comput Biol Med. 2016;70:119-130 pubmed publisher
    ..34±1.94mm. The proposed algorithm converges faster and produces more correct results than the conventional method in evaluations on patient datasets. ..
  80. Shin E, Lee Y, Koo J. Differential expression of the epigenetic methylation-related protein DNMT1 by breast cancer molecular subtype and stromal histology. J Transl Med. 2016;14:87 pubmed publisher
    ..001). Tumor expression of DNMT1 in breast cancer differed by molecular subtype and stromal histological type. DNMT1 was highly expressed in TNBC and in breast cancer with inflammatory stromal type. ..
  81. Jang S, Park J, Kim S, Choi K, Ko E, Cha J, et al. Oral administration of red ginseng powder fermented with probiotic alleviates the severity of dextran-sulfate sodium-induced colitis in a mouse model. Chin J Nat Med. 2017;15:192-201 pubmed publisher
    ..Collectively, oral administration of probiotic-fermented red ginseng reduced the severity of colitis in a mouse model, suggesting that it can be used as a uniformly effective red ginseng product. ..
  82. Kim J, Kim Y, Lee J, Jang Y, Chung I, Koo H. cDNA cloning, expression, and chromosomal localization of Caenorhabditis elegans DNA topoisomerase I. Eur J Biochem. 1996;237:367-72 pubmed
    ..The 72-kDa C-terminal polypeptide expressed in Escherichia coli cells showed catalytic DNA topoisomerase I activity. The DNA topoisomerase I gene was mapped to position 18 of chromosome I by screening polytene YAC plasmid DNAs. ..
  83. Kim S, Shin S. Loose bodies after arthroscopic osteochondral autograft in osteochondritis dissecans of the knee. Arthroscopy. 2000;16:E16 pubmed
    ..A large osteochondral defect can be treated successfully with arthroscopic autogenous bone graft. When filling the donor site with the recipient bone core, only the cancellous portion should be inserted into the donor socket. ..
  84. Park J, Kim G, Suh Y. Intrathyroidal branchial cleft-like cyst with heterotopic salivary gland-type tissue. Pediatr Dev Pathol. 2004;7:262-7 pubmed
    ..This association of branchial cleft-like cyst with SCNs and unusual heterotopic tissues in the normal thyroid suggests a possible origin from the SCN as ultimobranchial vestigial structures...
  85. Kwon J, Kim J. Sparganosis presenting as a conus medullaris lesion: case report and literature review of the spinal sparganosis. Arch Neurol. 2004;61:1126-8 pubmed
    ..We herein report, to our knowledge, the first case of sparganosis presenting as a conus medullaris lesion and review the literature of sparganosis involving the spinal cord...
  86. Park H, Lee M. Concurrent reactivation of varicella zoster virus and herpes simplex virus in an immunocompetent child. J Korean Med Sci. 2004;19:598-600 pubmed
    ..We present the case of an immunocompetent 8-yr-old female patient with concurrent reactivation of HSV on the face and VZV on the right L2 dermatome. ..
  87. Kim S, Park J, Lee J, Lee K, Lee J, Choi S, et al. A Phase II study of gemcitabine and cisplatin in advanced biliary tract cancer. Cancer. 2006;106:1339-46 pubmed
    ..In addition, the correlation between the CA 19-9 response and clinical outcome was analyzed...
  88. Noh S, Ahn J, Lee K, Kim S. Pituitary adenoma and concomitant Rathke's cleft cyst. Acta Neurochir (Wien). 2007;149:1223-8 pubmed
    ..When a non-enhancing cyst-like structure is demonstrated on imaging in a patient with a pituitary adenoma, the possibility of a coexisting Rathke's cleft cyst should be considered...
  89. Ko E, Han B, Shin J, Kang S. Breast MRI for evaluating patients with metastatic axillary lymph node and initially negative mammography and sonography. Korean J Radiol. 2007;8:382-9 pubmed
    ..Localization of the lesions through MR-correlated mammography and second-look sonography is practically feasible in most cases. ..
  90. Park S, Kang Y, Jeong M, Yoon H, Han K. Frequencies of CYP3A5 genotypes and haplotypes in a Korean population. J Clin Pharm Ther. 2008;33:61-5 pubmed publisher
    ..A large proportion of Koreans may have relatively low levels of metabolically active CYP3A5 protein and therefore may be at risk of high levels of drugs metabolized by this enzyme, after administration of conventional doses. ..
  91. Kang S, Kim T, Kim H, Yoon J, Cho H, Yoon S, et al. Protective role of CYP1A1*2A in the development of multiple myeloma. Acta Haematol. 2008;119:60-4 pubmed publisher
    ..The associations of polymorphisms of metabolizing enzymes with the risk for MM differed between Koreans and Caucasians, suggesting an ethnic variation in the susceptibility to MM. ..
  92. Choi Y, Kim K. AKAP12 in astrocytes induces barrier functions in human endothelial cells through protein kinase Czeta. FEBS J. 2008;275:2338-53 pubmed publisher
    ..We therefore suggest that AKAP12 in astrocytes differentially regulates the expression of VEGF and TSP-1 via the inhibition of PKCzeta phosphorylation and Rho kinase activity in HRMECs. ..