Experts and Doctors on cd antigens in Seoul, South Korea


Locale: Seoul, South Korea
Topic: cd antigens

Top Publications

  1. Kim H, Lim J, Park H, Lee S. Increased immunoendocrine cells in intestinal mucosa of postinfectious irritable bowel syndrome patients 3 years after acute Shigella infection--an observation in a small case control study. Yonsei Med J. 2010;51:45-51 pubmed publisher
    ..Our findings in a very small number of patients suggest that mucosal inflammation may play a role in long-term PI-IBS, and that other sub-groups of IBS and larger scale studies are needed to confirm this observation. ..
  2. Park K, Baek J, Do J, Bang D, Lee E. CTLA4 gene polymorphisms and soluble CTLA4 protein in Behcet's disease. Tissue Antigens. 2009;74:222-7 pubmed publisher
  3. Park D, Shim J. Histologic influence of doxazosin and finasteride in benign prostatic hyperplasia accompanying chronic inflammation. Urol Int. 2008;81:441-6 pubmed publisher
    ..These findings suggest that finasteride may interfere with the anti-inflammatory reaction. Finasteride also decreases angiogenesis. However, the meaning of our observations is limited by small sample size. ..
  4. Ko H, Kim Y, Kim Y, Chang W, Ko S, Chang S, et al. A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model. Cancer Res. 2007;67:7477-86 pubmed
    ..When combined with immunotherapies, gemcitabine offers a promising strategy for the Ag-specific treatment of human cancer. ..
  5. Ree H, Kadin M, Kikuchi M, Ko Y, Go J, Suzumiya J, et al. Angioimmunoblastic lymphoma (AILD-type T-cell lymphoma) with hyperplastic germinal centers. Am J Surg Pathol. 1998;22:643-55 pubmed
    ..We conclude that hyperplastic germinal centers with ill-defined borders and frequent interfollicular tingible-body macrophages occur in a histologic variant of AITL that is necessary to recognize for early diagnosis and treatment. ..
  6. Kim S, Cho H, Yang S, Shin J, Kim J, Lee S, et al. Soluble mediators from human neural stem cells play a critical role in suppression of T-cell activation and proliferation. J Neurosci Res. 2009;87:2264-72 pubmed publisher
    ..These results show that hNSCs can negatively affect human peripheral T cells by suppressing their activation and proliferation through soluble mediators, suggesting that hNSCs have a bystander immunomodulatory effect on T cells. ..
  7. Lim J, Kim S, Park S, Yang J, Kim M, Ryu H. Effective prediction of preeclampsia by a combined ratio of angiogenesis-related factors. Obstet Gynecol. 2008;111:1403-9 pubmed publisher
    ..The combined ratio of angiogenesis-related factors showed the lowest false-positive rate and the highest OR for prediction of preeclampsia, indicating that it may provide more effective prediction of development of preeclampsia. II. ..
  8. Gang E, Jeong J, Han S, Yan Q, Jeon C, Kim H. In vitro endothelial potential of human UC blood-derived mesenchymal stem cells. Cytotherapy. 2006;8:215-27 pubmed
    ..These observations have led us to conclude that UCB-derived MSC retain endothelial potential that is suitable for basic and clinical studies aimed at the development of vasculature-directed regenerative medicine. ..
  9. Park S, Shin Y, Suh Y, Park W, Ban Y, Choi H, et al. Rapid divergency of rodent CD99 orthologs: implications for the evolution of the pseudoautosomal region. Gene. 2005;353:177-88 pubmed

More Information


  1. Yoo S, Han J, Kim T, Chung D. Expression of CD99 in pleomorphic carcinomas of the lung. J Korean Med Sci. 2005;20:50-5 pubmed
    ..A clinicopathological analysis showed no direct correlation between the expression of CD99 and the clinical indices (stage, survival rate, invasion) of PCL. ..
  2. Sohn B, Kim T, Kim J, Bae E, Park C, Huh J, et al. A case of histiocytic sarcoma presenting with primary bone marrow involvement. J Korean Med Sci. 2010;25:313-6 pubmed publisher
    ..Morphologic findings also distinguished it from other dendritic cell neoplasms. ..
  3. Jeon Y, Kim S, Choi S, Kim K, Yoo B, Ku J, et al. Promoter hypermethylation and loss of CD133 gene expression in colorectal cancers. World J Gastroenterol. 2010;16:3153-60 pubmed
    ..The study may contribute to the understanding of the role of CD133 inactivation in the progression of colorectal cancers. ..
  4. Lee W, Erm S, Kim K, Becker R. Emperipolesis of erythroblasts within Kupffer cells during hepatic hemopoiesis in human fetus. Anat Rec. 1999;256:158-64 pubmed
    ..We suggest that emperipolesis may be one of the mechanisms that support the maturation of erythroblasts in the fetal liver. ..
  5. Gu J, Lim S, Oh S, Yoon S, Seong J, Jung G. HBx modulates iron regulatory protein 1-mediated iron metabolism via reactive oxygen species. Virus Res. 2008;133:167-77 pubmed publisher
    ..2.15 cells that constitutively replicate the intact HBV genome. In conclusion, these results suggest that HBx modulates iron metabolism via ROS leading to pathological status in liver diseases...
  6. Park J, Jang M, Chung Y, Kim K, Kim S, Lee W, et al. Doxorubicin enhances CD4(+) T-cell immune responses by inducing expression of CD40 ligand and 4-1BB. Int Immunopharmacol. 2009;9:1530-9 pubmed publisher
    ..Our results collectively suggest that doxorubicin pre-treatment in cancer patients may be a more effective way to enhance anti-cancer immune responses by increased antigen-specific CD4(+) Th1 immune responses. ..
  7. Park J, Park S, So K, Bae I, Yoo Y, Um H. ICAM-3 enhances the migratory and invasive potential of human non-small cell lung cancer cells by inducing MMP-2 and MMP-9 via Akt and CREB. Int J Oncol. 2010;36:181-92 pubmed
  8. Lee E, Han G, Park H, Song Y, Kim C. Transgelin promotes migration and invasion of cancer stem cells. J Proteome Res. 2010;9:5108-17 pubmed publisher
    ..Taken together, these results indicate that the metastatic potential of CSCs arises from highly expressed Transgelin. ..
  9. Seo B, Lee K, Ha J, Park H, Choi J, Lee K. Saucernetin-7 isolated from Saururus chinensis inhibits proliferation of human promyelocytic HL-60 leukemia cells via G0/G1 phase arrest and induction of differentiation. Carcinogenesis. 2004;25:1387-94 pubmed
    ..This is the first report demonstrating that saucernetin-7 potently inhibits the proliferation of human promyelocytic HL-60 cells via the G1 phase cell cycle arrest and differentiation induction...
  10. Chun J, Kang D, Yoo B, Shin J, Kim D. Programmed death-1 (PD-1) gene polymorphisms lodged in the genetic predispositions of Kawasaki Disease. Eur J Pediatr. 2010;169:181-5 pubmed publisher
    ..Our data support the possibility that PD-1 gene polymorphism may be related with the genetic susceptibility of KD in Korean population. ..
  11. Choi J, Kim S, Cha J, Choi Y, Sung K, Oh S, et al. Upregulation of gp130 and STAT3 activation in the rat hippocampus following transient forebrain ischemia. Glia. 2003;41:237-46 pubmed
  12. Kim S, Choi Y, Choi J, Cha J, Kim O, Lee S, et al. Osteopontin in kainic acid-induced microglial reactions in the rat brain. Mol Cells. 2002;13:429-35 pubmed
    ..It can therefore be assumed that in the response of the brain to excitotoxic injury, synthesis of OPN occurs generally in a subset of activated microglia. ..
  13. Lee E, Yoo J, Lee Y, Choi Y, Park K, Song Y. Tumor necrosis factor receptor 2 polymorphism in systemic lupus erythematosus: no association with disease. Hum Immunol. 2001;62:1148-52 pubmed
    ..Further studies in other populations will be needed to elucidate the role of the TNFR2 polymorphism in the development of SLE. ..
  14. Kim S, Im J, Yun C, Son J, Son C, Park D, et al. Armillariella mellea induces maturation of human dendritic cells without induction of cytokine expression. J Ethnopharmacol. 2008;119:153-9 pubmed publisher
    ..Armillariella mellea induces maturation of human DCs through a unique mechanism without inducing cytokine expression. ..
  15. Lee Y, Kim Y, Ji J, Sohn J, Song G. Polymorphisms of the CTLA-4 exon 1 and promoter gene in systemic lupus erythematosus. Lupus. 2001;10:601-5 pubmed
    ..05. Clinically, in the lupus patients there was no significant difference according to the CTLA-4 polymorphisms. In conclusion, no correlation was found between CTLA-4 exon 1 (+49) and promoter (-318) polymorphisms and SLE in our study. ..
  16. Chung Y, Kim B, Park C, Huh S, Kim J, Park J, et al. Increased expression of ICAM-3 is associated with radiation resistance in cervical cancer. Int J Cancer. 2005;117:194-201 pubmed
  17. Cho G, Koh S, Kim M, Yoo A, Noh M, Oh S, et al. The neuroprotective effect of erythropoietin-transduced human mesenchymal stromal cells in an animal model of ischemic stroke. Brain Res. 2010;1353:1-13 pubmed publisher
    ..Transduction of the EPO gene into MSCs induced secretion of EPO and various trophic factors that may provide excellent neuroprotective effects in both in vitro and in vivo models of ischemic stroke. ..
  18. Lee S, Lee Y, Shin C, Shim J, Kang K, Yoo S, et al. Association of asthma severity and bronchial hyperresponsiveness with a polymorphism in the cytotoxic T-lymphocyte antigen-4 gene. Chest. 2002;122:171-6 pubmed
    ..019). The CTLA-4 promoter (-318 C/T) T allele may serve as a clinically useful marker of severe asthma. The CTLA-4 exon 1 (+49 A/G) polymorphism may have a disease-modifying effect in asthmatic airways. ..
  19. Kim K, Park Y, Kim T, Park D, Park K, Cho B. Susceptible alleles of the CD40 and CTLA-4 genes are not associated with the relapse after antithyroid withdrawal in Graves' disease. Thyroid. 2007;17:1229-34 pubmed
    ..These findings suggest that the genetic markers associated with the development of GD cannot be used to predict the relapse of GD patients in place of clinical parameters. ..
  20. Kim S, Kim S, Kang H, Chung H, Choi I, Cheon Y, et al. Molecular cloning and expression analysis of pig lymphocyte activation gene-3 (LAG-3; CD223). Vet Immunol Immunopathol. 2010;133:72-9 pubmed publisher
    ..These results indicated that the structure and expression pattern of pig LAG-3 are conserved among mammalian species. ..
  21. Kim K, Choi J, Chae W, Lee S. Synergistic inhibition of T-cell activation by a cell-permeable ZAP-70 mutant and ctCTLA-4. Biochem Biophys Res Commun. 2009;381:355-60 pubmed publisher
    ..This is the first report to demonstrate the synergistic inhibition of signals transmitted via TcR and its co-stimulatory receptor by cell-permeable forms of intracellular signal mediators. ..
  22. Jue S, Lee W, Kwon Y, Kim Y, Pae A, Lee B. The effects of enamel matrix derivative on the proliferation and differentiation of human mesenchymal stem cells. Clin Oral Implants Res. 2010;21:741-6 pubmed publisher
    ..Because most of the organic matrix of bone is type I collagen, which acts as the mineralization site, bone or bone-like mineralized mass might have been formed in spite of the different components of the non-collagenous proteins. ..
  23. Um H, Cho Y, Kim D, Shin J, Lee Y, Choi K, et al. TNF-alpha suppresses dendritic cell death and the production of reactive oxygen intermediates induced by plasma withdrawal. Exp Dermatol. 2004;13:282-8 pubmed
    ..To summarize, our results suggest that TNF-alpha controls not only the inflammatory functions of DCs but also their survival. ..
  24. Jeon D, Oh K, Oh B, Nam D, Kim C, Park H, et al. Porcine PD-L1: cloning, characterization, and implications during xenotransplantation. Xenotransplantation. 2007;14:236-42 pubmed
    ..The authors suggest that PD-1-PD-L1 might play an important endogenous immune regulatory role during xenogeneic transplantation, and that the effective application of this system would improve transplanted xenogeneic organ survival. ..
  25. Lee Y, Ji J, Sohn J, Song G. Polymorphsims of CTLA-4 exon 1 +49, CTLA-4 promoter -318 and Fas promoter -670 in spondyloarthropathies. Clin Rheumatol. 2001;20:420-2 pubmed
    ..However, further studies are required to discover the possible contribution of the polymorphisms of the CTLA-4 and Fas to the pathogenesis of SpA. ..
  26. Kim H, Kim H, Kim Y, Park S, Harris R, Kim C. Caveolin, GLUT4 and insulin receptor protein content in human arm and leg muscles. Eur J Appl Physiol. 2009;106:173-9 pubmed publisher
    ..Although Cav-3, GLUT4, and IR-beta were unchanged from the resting levels at the end of both exercise trials in DEL, all measures, including Cav-1, increased after the 1,500 m swim trial in VAS. ..
  27. Kim S, Lee J, Kim S, Jee Y, Kim Y, Park H, et al. Allelic variants of CD40 and CD40L genes interact to promote antibiotic-induced cutaneous allergic reactions. Clin Exp Allergy. 2009;39:1852-6 pubmed publisher
    ..017, odds ratio (OR) (95% confidence interval)=2.93 (1.20-7.97)]. Our findings suggest that a genetic interaction between CD40 and CD40L favours the development of AICARs. ..
  28. Kim W, Kim H, Jeon Y, Kim C. Follicular dendritic cell sarcoma with immature T-cell proliferation. Hum Pathol. 2010;41:129-33 pubmed publisher
    ..The complication of myasthenia gravis and paraneoplastic pemphigus may suggest that immature T-cell proliferation has an autoimmunity-related systemic influence. ..
  29. Sung C, Ko Y, Park S, Kim K, Kim W. Immunoreactivity of CD99 in non-Hodgkin's lymphoma: unexpected frequent expression in ALK-positive anaplastic large cell lymphoma. J Korean Med Sci. 2005;20:952-6 pubmed
    ..High expression of CD99 in ALK-positive ALCL is unexpected finding and its biologic and clinical significances have yet to be clarified. ..
  30. Kim E, Kim N, Kim T, Kim K, Kim T, Kumar V, et al. Unidirectional signaling triggered through 2B4 (CD244), not CD48, in murine NK cells. J Leukoc Biol. 2010;88:707-14 pubmed publisher
    ..Therefore, our results demonstrate unequivocally that CD48 on surrounding NK or non-NK cells serves primarily as a ligand to stimulate 2B4 on the adjacent NK cells in mice. ..
  31. Choi D, Lee H, Hur K, Kim J, Park G, Jang S, et al. Cancer stem cell markers CD133 and CD24 correlate with invasiveness and differentiation in colorectal adenocarcinoma. World J Gastroenterol. 2009;15:2258-64 pubmed
    ..001). Survival was not significantly related to CD133, CD24 and CD44 expression. CD markers were related to invasiveness and differentiation of colorectal adenocarcinoma. However, CD expression was not closely related to survival. ..
  32. Limb J, Yoon S, Lee K, Kim B, Lee S, Bae Y, et al. Regulation of megakaryocytic differentiation of K562 cells by FosB, a member of the Fos family of AP-1 transcription factors. Cell Mol Life Sci. 2009;66:1962-73 pubmed publisher
    ..We define 3 genes, INHBA, CD9, and ITGA2B as regulatory targets of FosB and show that CD9, in particular, is a direct target of FosB. ..
  33. Lim J, Kim S, Park S, Lee M, Yang J, Kim M, et al. Soluble endoglin and transforming growth factor-beta1 in women who subsequently developed preeclampsia. Prenat Diagn. 2009;29:471-6 pubmed publisher
    ..Early midtrimester plasma levels of sEng are predictive of subsequence occurrence and severity of preeclampsia, in terms of severity of hypertension and proteinuria, prematurity, and association with small for gestational age neonates. ..
  34. Cho T, Seo J, Lee H, Yoo W, Chung C, Choi I. Biologic characteristics of fibrous hamartoma from congenital pseudarthrosis of the tibia associated with neurofibromatosis type 1. J Bone Joint Surg Am. 2008;90:2735-44 pubmed publisher
    ..We investigated the biologic characteristics of fibrous hamartoma cells in order to better understand the pathogenesis of this rare disease...
  35. Kim D, Hur D, Kim Y, Lee K, Lee Y, Cho D, et al. CM1 ligation initiates apoptosis in a caspase 8-dependent manner in Ramos cells and in a mitochondria-controlled manner in Raji cells. Hum Immunol. 2002;63:576-87 pubmed
    ..Moreover, the effector caspase inhibitor, z-DEVD, blocked CM1-mediated apoptosis in both cell lines. We found that CM1-induced apoptosis is achieved via different initiation pathways, which are cell-type dependent. ..
  36. Hong C, Lee J, Lee H, Bae S, Yoo D. The association between fcgammaRIIIB polymorphisms and systemic lupus erythematosus in Korea. Lupus. 2005;14:346-50 pubmed
    ..0-5.4), and NA2 allele (P = 0.03, OR 1.7, 95% CI 1.1-2.8). Although FcgammaRIIIB polymorphism was not associated with the development of SLE in Korean, thrombocytopenia was associated with FcgammaRIIIB NA2/NA2 genotype, and NA2 allele. ..
  37. Kim J, Kim H, Lee S, Choi Y, Lee S, Lee J. Abundance of ADAM-8, -9, -10, -12, -15 and -17 and ADAMTS-1 in mouse uterus during the oestrous cycle. Reprod Fertil Dev. 2005;17:543-55 pubmed
    ..From these observations, we suggest that the ADAM genes play an important role in mouse uterine tissue remodelling during the oestrous cycle. ..
  38. Kim S, Park H, Choi J, Lee J, Cha J, Choi Y, et al. Ischemic preconditioning-induced expression of gp130 and STAT3 in astrocytes of the rat hippocampus. Brain Res Mol Brain Res. 2004;129:96-103 pubmed
  39. Jang H, Yoon K, Shin Y, Kim J, Lee S. PIAS3 suppresses NF-kappaB-mediated transcription by interacting with the p65/RelA subunit. J Biol Chem. 2004;279:24873-80 pubmed
    ..Taken together, these data suggest that PIAS3 may function in vivo as a modulator in suppressing the transcriptional activity of p65. ..
  40. Lim J, Kim J, Lee J, Joo C. Downregulated expression of integrin alpha6 by transforming growth factor-beta(1) on lens epithelial cells in vitro. Biochem Biophys Res Commun. 2001;284:33-41 pubmed
    ..These findings suggest that the reduced expression of integrin alpha6 caused by TGF-beta(1) might play a role in the activation of the cell cycle genes required during the fiber differentiation of the lens. ..
  41. Chang M, Park C, Son H, Lee Y, Lee S. Developmental stage-dependent self-regulation of embryonic cortical precursor cell survival and differentiation by leukemia inhibitory factor. Cell Death Differ. 2004;11:985-96 pubmed
  42. Chang S, Kweon M. Langerin-expressing dendritic cells in gut-associated lymphoid tissues. Immunol Rev. 2010;234:233-46 pubmed publisher
    ..In this review, we focus on the phenotypic and functional characteristics of langerin(+) DCs in the mucosal tissues, especially MLNs. ..
  43. Jin H, Park S, Oh W, Yang Y, Kim S, Choi S. Down-regulation of CD105 is associated with multi-lineage differentiation in human umbilical cord blood-derived mesenchymal stem cells. Biochem Biophys Res Commun. 2009;381:676-81 pubmed publisher
    ..We propose that CD105 is a useful novel marker to characterize differentiation status of isolated human UCB-MSCs, which will be useful to facilitate the application of such cells in stem-cell therapy. ..
  44. Choi E, Kim D, Hong B, Kwon H, Song Y, Byun K, et al. Upregulation of extracellular matrix metalloproteinase inducer (EMMPRIN) and gelatinases in human atherosclerosis infected with Chlamydia pneumoniae: the potential role of Chlamydia pneumoniae infection in the progression of atherosclerosis. Exp Mol Med. 2002;34:391-400 pubmed
    ..The present study demonstrated upstream regulation of MMPs can be induced by C. pneumoniae within atheromatous plaque itself. These findings help to understand the potential role of C. pneumoniae in the progression of atherosclerosis. ..
  45. Kim K, Jun S, Kim J, Ro J. Implantation site intermediate trophoblasts in placenta cretas. Mod Pathol. 2004;17:1483-90 pubmed
  46. Kim J, Kim B, Cai L, Choi H, Ohgi K, Tran C, et al. Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes. Nature. 2005;434:921-6 pubmed
  47. Lee E, Oh B, Lee J, Kimm K, Lee S, Baek K. A novel single nucleotide polymorphism of INSR gene for polycystic ovary syndrome. Fertil Steril. 2008;89:1213-20 pubmed
    ..Among the analyzed SNPs, +176477 C>T, a novel SNP in the INSR gene, was associated with the pathogenesis of PCOS in a Korean population. ..
  48. Yoon I, Choi S, Kim Y, Yang S, Park J, Park C, et al. Pancreatic islets induce CD4(+) [corrected] CD25(-)Foxp3(+) [corrected] T-cell regulated tolerance to HY-mismatched skin grafts. Transplantation. 2008;86:1352-60 pubmed publisher
    ..Unmanipulated pancreatic islets can induce immunologic tolerance associated with peripherally induced CD4+Foxp3+ Tregs, a significant proportion of which notably are CD25-. ..
  49. Park J, Choi H, Prabagar M, Choi W, Kim S, Cheong C, et al. The C-type lectin CD209b is expressed on microglia and it mediates the uptake of capsular polysaccharides of Streptococcus pneumoniae. Neurosci Lett. 2009;450:246-51 pubmed publisher
    ..Our findings strongly suggest that both rat CD209b and SIGN-R1 on microglia mediate the SIGN-R1 complement activation pathway against S. pneumoniae, and thereby plays an important role in the pathogenesis of pneumococcal meningitis. ..
  50. Kang J, Kang K, Koo H, Park J, Choi E, Park Y. Soluble factors-mediated immunomodulatory effects of canine adipose tissue-derived mesenchymal stem cells. Stem Cells Dev. 2008;17:681-93 pubmed publisher
    ..Therefore, it is suggested that cAD-MSCs have a potential therapeutic use in the treatment of immune-mediated disease. ..
  51. Lee E, Lee H, Park S, Choi E, Park S. CD99 type II is a determining factor for the differentiation of primitive neuroectodermal cells. Exp Mol Med. 2003;35:438-47 pubmed
    ..Our data suggest that CD99 type II acts as a negative regulator in the neural differentiation of precursor cells that might occur during nerve system development. ..
  52. Lee S, Kim H, Kim S, Lee Y, Park W, Kim S, et al. Increased expression of FLIP, an inhibitor of Fas-mediated apoptosis, in stomach cancer. APMIS. 2003;111:309-14 pubmed
  53. Na Y, Seok S, Kim D, Han J, Kim T, Jung H, et al. Isolation and characterization of spheroid cells from human malignant melanoma cell line WM-266-4. Tumour Biol. 2009;30:300-9 pubmed publisher
    ..However, the existence of spheroid cells in WM-266-4, a human malignant metastatic melanoma cell line, has not yet been reported...
  54. Lee Y, Woo J, Choi S, Ji J, Song G. Association of programmed cell death 1 polymorphisms and systemic lupus erythematosus: a meta-analysis. Lupus. 2009;18:9-15 pubmed publisher
    ..031). In conclusion, this meta-analysis demonstrated an association of the PD1.3A allele with LN in European and SLE in Latin-American populations. Furthermore, the PD1.5C allele was associated with SLE susceptibility in Europeans. ..
  55. Jeong K, Lee T, Ihm C, Lee S, Moon J, Lim S. Effects of sildenafil on oxidative and inflammatory injuries of the kidney in streptozotocin-induced diabetic rats. Am J Nephrol. 2009;29:274-82 pubmed publisher
    ..Cortical MCP-1 RNA expression in the sildenafil group was significantly lower than in the nonsildenafil group. Sildenafil treatment may attenuate renal damage by ameliorating oxidative and inflammatory injuries in diabetic rats. ..
  56. Ha Y, Lee J, Kim K, Cho Y, Yoon D. Intermediate filament nestin expressions in human cord blood monocytes (HCMNCs). Acta Neurochir (Wien). 2003;145:483-7 pubmed
    ..In the present study, we found that more than 60% of CD133 expressing HCMNCs also express nestin antigen in their cytoplasm, which supports the idea that cord blood stem cells can adopt a neuronal fate. ..
  57. Yoon Y, Kwon H, Hwang K, Choi E, Hong B, Kim D, et al. Upstream regulation of matrix metalloproteinase by EMMPRIN; extracellular matrix metalloproteinase inducer in advanced atherosclerotic plaque. Atherosclerosis. 2005;180:37-44 pubmed
    ..ECM remodeling is under the control of induction and inhibition of matrix degrading protease and the novel MMP inducer, EMMPRIN may play a role in influx and differentiation of monocytes and destabilizing atheroma. ..
  58. Sohn M, Kim S, Song T, Kim K, Kim E, Park H, et al. Cytotoxic T lymphocyte-associated antigen-4 gene polymorphisms confer susceptibility to atopic asthma in Korean children. Pediatr Pulmonol. 2007;42:542-7 pubmed
    ..01, OR=0.702, 95% CI= 0.541-0.911). Polymorphisms in the CTLA-4 gene likely confer susceptibility to atopic asthma in Korean children. ..
  59. Choi I, Cho B, Kim S, Park D, Kim J, Park C, et al. Molecular cloning, expression and functional characterization of miniature swine CD86. Mol Immunol. 2006;43:480-6 pubmed
  60. Chun T, Cho H, Chung Y. Cloning of rat lymphocyte activation gene-3 (Lag3; CD223) cDNA and its mRNA expression in rat tissues. Eur J Immunogenet. 2004;31:5-9 pubmed
    ..Rat Lag3 mRNA transcript was detected as a single species of approximately 2 kb from phytohemagglutinin (PHA)-stimulated lymphocytes. Further analysis revealed that rat Lag3 mRNA was mainly expressed in lymphoid tissues. ..
  61. Yun H, Koh H, Kim S, Chung W, Kim D, Hong K, et al. FcgammaRIIa/IIIa polymorphism and its association with clinical manifestations in Korean lupus patients. Lupus. 2001;10:466-72 pubmed
    ..In contrast to other ethnic patients, in our study cohort, clinical manifestation was different between male and female, and FcgammaRIIa and FcgammaRIIIa showed somewhat different clinical associations between the genders. ..
  62. Kim T, Park Y, Hwang J, Song J, Park K, Cho B, et al. A C/T polymorphism in the 5'-untranslated region of the CD40 gene is associated with Graves' disease in Koreans. Thyroid. 2003;13:919-25 pubmed
    ..However, clinical characteristics and other thyroid antibodies were not significantly different. In conclusion, the C allele in the 5'-untranslated region of the CD40 gene may confer genetic susceptibility to Graves' disease in Koreans. ..
  63. Choi J, Kim S, Park H, Cha J, Choi Y, Kang J, et al. Upregulation of gp130 and differential activation of STAT and p42/44 MAPK in the rat hippocampus following kainic acid-induced seizures. Brain Res Mol Brain Res. 2003;119:10-8 pubmed
  64. Lee S, Kim J, Jang S, Kim D, Do Y, Suh G, et al. Clinical features and mutations in the ENG, ACVRL1, and SMAD4 genes in Korean patients with hereditary hemorrhagic telangiectasia. J Korean Med Sci. 2009;24:69-76 pubmed publisher
    ..Despite the small number of patients investigated, we firstly report Korean patients with genetically confirmed HHT, and show the genetic and allelic heterogeneity underlying HHT. ..
  65. Cho K, Kim S, Park C, Park J, Cho J, Kang H, et al. Molecular cloning and expression analysis of pig CD81. Vet Immunol Immunopathol. 2007;120:254-9 pubmed
    ..Future study will be focused on defining the functional role of CD81 during the course of pig infectious diseases. ..
  66. Shim H, Kim J, Kim M, Sim H, Park D, Sohn J, et al. Legionella lipoprotein activates toll-like receptor 2 and induces cytokine production and expression of costimulatory molecules in peritoneal macrophages. Exp Mol Med. 2009;41:687-94 pubmed publisher
    ..In conclusions, these results indicate that Legionella PAL might activate macrophages via a TLR2-dependent mechanism which thus induce cytokine production and expression of costimulatory and MHC molecules...
  67. Jeong S, Koo S, Choi J, Park J, Ha J, Park H, et al. Intermedeol isolated from the leaves of Ligularia fischeri var. spiciformis induces the differentiation of human acute promyeocytic leukemia HL-60 Cells. Planta Med. 2002;68:881-5 pubmed
    ..Taken together, our results suggest that intermedeol may have potential as a therapeutic agent in human leukemia. ..
  68. Jung M, Yu J, Shin C, Suh B, Yang S, Lee B. Association of cytotoxic T lymphocyte antigen-4 gene polymorphisms and HLA class II alleles with the development of type 1 diabetes in Korean children and adolescents. J Korean Med Sci. 2009;24:1004-9 pubmed publisher
    ..However, a CTLA4-mediated susceptibility effect on the development of T1D might be significant in children and adolescents that do not have susceptible HLA class II alleles. ..
  69. An S, Kim S, Huh Y, Lee T, Kim H, Park K, et al. Expression of surface markers on the human monocytic leukaemia cell line, THP-1, as indicators for the sensitizing potential of chemicals. Contact Dermatitis. 2009;60:185-92 pubmed publisher
    ..These data suggest that the THP-1 cells are good model for screening contact sensitizers and CD40 could be a useful marker complementary to CD54 and CD86. ..