Experts and Doctors on interphase in Singapore, Central Singapore, Singapore
Locale: Singapore, Central Singapore, Singapore
Chin C, Yeong F. Safeguarding entry into mitosis: the antephase checkpoint. Mol Cell Biol. 2010;30:22-32 pubmed publisher
..We highlight issues which are unresolved in terms of our understanding of the antephase checkpoint and provide some perspectives on what lies ahead in the understanding of how the checkpoint functions. ..
Gan F, Nagle A, Ang X, Ho O, Tan S, Yang H, et al
. Shogaols at proapoptotic concentrations induce G(2)/M arrest and aberrant mitotic cell death associated with tubulin aggregation. Apoptosis. 2011;16:856-67 pubmed publisher
..In summary, our results conclude that shogaols cause apoptosis by inducing aberrant mitosis at least through the attenuation of cell cycle and spindle assembly checkpoint proteins. ..
Liu J, Wang H, Balasubramanian M. A checkpoint that monitors cytokinesis in Schizosaccharomyces pombe. J Cell Sci. 2000;113 ( Pt 7):1223-30 pubmed
..We conclude that an F-actin and Wee1p dependent checkpoint blocks G(2)/M transition until previous cytokinesis is completed. ..
Wasser M, Chia W. The Drosophila EAST protein associates with a nuclear remnant during mitosis and constrains chromosome mobility. J Cell Sci. 2003;116:1733-43 pubmed
..We propose that EAST constitutes a component of a nucleoskeleton that helps to constrain the mobility of chromosomes in interphase, mitosis and meiosis. ..
Lau L, Kee S, Tien S, Koh Mickey B. Trisomy 8 as sole cytogenetic abnormality in a case of chronic lymphocytic leukemia. Cancer Genet Cytogenet. 2007;172:66-9 pubmed
..Trisomy 8 as the sole chromosomal abnormality in CLL is a very rare finding. The prognostic significance of trisomy 8 in CLL remains to be seen...
Xu L, Huang M, Fang S, Liu D. Coronavirus infection induces DNA replication stress partly through interaction of its nonstructural protein 13 with the p125 subunit of DNA polymerase ?. J Biol Chem. 2011;286:39546-59 pubmed publisher
..These findings indicate that the ATR signaling activated by IBV replication contributes to the IBV-induced S-phase arrest and is required for efficient IBV replication and progeny production. ..