Experts and Doctors on anxiety in Singapore, Central Singapore, Singapore


Locale: Singapore, Central Singapore, Singapore
Topic: anxiety

Top Publications

  1. Zhen Lu W, Ann Gwee K, Yu Ho K. Functional bowel disorders in rotating shift nurses may be related to sleep disturbances. Eur J Gastroenterol Hepatol. 2006;18:623-7 pubmed
    ..The FBD symptom score was positively and independently correlated with the sleep disturbance score, suggesting that poor sleep might be associated with increased FBD symptoms in rotating shift nurses. ..
  2. Koe A, Ashokan A, Mitra R. Short environmental enrichment in adulthood reverses anxiety and basolateral amygdala hypertrophy induced by maternal separation. Transl Psychiatry. 2016;6:e729 pubmed publisher
    ..These observations argue that behavioural plasticity induced by early adversity can be rescued by environmental interventions much later in life, likely mediated by ameliorating effects of enrichment on basolateral amygdala plasticity. ..
  3. Tam W, Lo K, Hui D. The effect of music during bronchoscopy: A meta-analysis. Heart Lung. 2016;45:86-94 pubmed publisher
    ..57) and -4.84 (-7.78, -1.90) mm Hg, respectively, whereas that for heart rate was -10.57 (-16.63, -4.51) beats per minute. In conclusion, listening to music reduced blood pressure and heart rate among patients undergoing bronchoscopy. ..
  4. Griva K, Kang A, Yu Z, Lee V, Zarogianis S, Chan M, et al. Predicting technique and patient survival over 12 months in peritoneal dialysis: the role of anxiety and depression. Int Urol Nephrol. 2016;48:791-6 pubmed publisher
    ..Anxiety is an important predictor of actuarial and technique survival in PD. Effective treatment for symptoms of anxiety may represent an easily achievable means of improving the clinical outcome of PD patients. ..
  5. Griva K, Goh C, Kang W, Yu Z, Chan M, Wu S, et al. Quality of life and emotional distress in patients and burden in caregivers: a comparison between assisted peritoneal dialysis and self-care peritoneal dialysis. Qual Life Res. 2016;25:373-384 pubmed publisher
    ..Our findings of mostly comparable patient and caregiver outcomes in assisted PD and self-care PD suggest that caregiver burden and QoL should not be a barrier to using assisted PD. ..
  6. He H, Zhu L, Chan S, Klainin Yobas P, Wang W. The effectiveness of therapeutic play intervention in reducing perioperative anxiety, negative behaviors, and postoperative pain in children undergoing elective surgery: a systematic review. Pain Manag Nurs. 2015;16:425-39 pubmed publisher
    ..More studies on the effectiveness of therapeutic play intervention using rigorous designs and involving parents are needed. ..
  7. Kocovski N, Fleming J, Hawley L, Ho M, Antony M. Mindfulness and acceptance-based group therapy and traditional cognitive behavioral group therapy for social anxiety disorder: Mechanisms of change. Behav Res Ther. 2015;70:11-22 pubmed publisher
    ..Results for acceptance were less clear. Cognitive reappraisal may be a more important mechanism of change for CBGT than MAGT, whereas mindfulness may be an important mechanism of change for both treatments. ..
  8. Gullick J, Kwan X. Patient-directed music therapy reduces anxiety and sedation exposure in mechanically-ventilated patients: a research critique. Aust Crit Care. 2015;28:103-5 pubmed publisher
    ..The self-directed use of music therapy and noise-cancelling headphones means these findings may not transfer to sedated or cognitively-impaired patients. ..
  9. Shah L, Torres S, Kannusamy P, Chng C, He H, Klainin Yobas P. Efficacy of the virtual reality-based stress management program on stress-related variables in people with mood disorders: the feasibility study. Arch Psychiatr Nurs. 2015;29:6-13 pubmed publisher
    ..77, p<0.001). Participants' feedback on the program was positive. Findings from this study contribute to improving clinical practice and serve as preliminary data to conduct more rigorous research in the future. ..

More Information


  1. Rees G, Xie J, Chiang P, Larizza M, Marella M, Hassell J, et al. A randomised controlled trial of a self-management programme for low vision implemented in low vision rehabilitation services. Patient Educ Couns. 2015;98:174-81 pubmed publisher
    ..When implementing self-management programmes in low vision rehabilitation settings, issues of client interest, divergence of need, programme accessibility and fidelity of intervention delivery need to be addressed. ..
  2. Lim C, Devi M, Ang E. Anxiety in women with breast cancer undergoing treatment: a systematic review. Int J Evid Based Healthc. 2011;9:215-35 pubmed publisher
    ..Healthcare professionals should pay greater attention to identify signs of anxiety in patients and design interventions to help alleviate it earlier. ..
  3. Bong C, Lightdale J, Fredette M, Weinstock P. Effects of simulation versus traditional tutorial-based training on physiologic stress levels among clinicians: a pilot study. Simul Healthc. 2010;5:272-8 pubmed publisher
  4. Song G, Venkatraman V, Ho K, Chee M, Yeoh K, Wilder Smith C. Cortical effects of anticipation and endogenous modulation of visceral pain assessed by functional brain MRI in irritable bowel syndrome patients and healthy controls. Pain. 2006;126:79-90 pubmed
    ..The aberrant activation of endogenous pain inhibition appears to involve circuitry relating to anticipation as well as pain processing itself. ..
  5. Wang H, Wong P, Spiess J, Zhu Y. Cholecystokinin-2 (CCK2) receptor-mediated anxiety-like behaviors in rats. Neurosci Biobehav Rev. 2005;29:1361-73 pubmed
    ..CCK(2) receptor expression was greater in PVG hooded than in SD rats in the cortex and hippocampus. Genetic studies also demonstrated four differences in the DNA sequence of the CCK(2) receptor gene between the two rat strains. ..
  6. Nguyen L, Ma D, Shui G, Wong P, Cazenave Gassiot A, Zhang X, et al. Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid. Nature. 2014;509:503-6 pubmed publisher
    ..Our findings reveal an unexpected essential physiological role of plasma-derived LPCs in brain growth and function...
  7. Jesuthasan S. Fear, anxiety, and control in the zebrafish. Dev Neurobiol. 2012;72:395-403 pubmed publisher
    ..In particular, they point to an essential role for a circuit involving the posterior septum, medial habenula, and interpeduncular nucleus. This evolutionarily conserved circuit may fulfill a similar function in mammals. ..
  8. Wee N, Kandiah N, Acharyya S, Chander R, Ng A, Au W, et al. Depression and anxiety are co-morbid but dissociable in mild Parkinson's disease: A prospective longitudinal study of patterns and predictors. Parkinsonism Relat Disord. 2016;23:50-6 pubmed publisher
    ..They had distinct trajectories and different longitudinal relationships with demographic, motor, and non-motor factors that were unique to each disorder. ..
  9. Mohammad F, Aryal S, Ho J, Stewart J, Norman N, Tan T, et al. Ancient Anxiety Pathways Influence Drosophila Defense Behaviors. Curr Biol. 2016;26:981-6 pubmed publisher
    ..The presence of conserved neurogenetic pathways in the insect brain identifies Drosophila as an attractive genetic model for the study of anxiety and anxiety-related disorders, complementing existing rodent systems. ..
  10. Bichler Z, Lim H, Zeng L, Tan E. Non-motor and motor features in LRRK2 transgenic mice. PLoS ONE. 2013;8:e70249 pubmed publisher
    ..These mice did recapitulate mild Parkinsonian motor features at late stages but compensatory mechanisms modulating the progression of PD in these models should be further evaluated. ..
  11. Sung M, Fung D, Cai Y, Ooi Y. Pharmacological management in children and adolescents with pervasive developmental disorder. Aust N Z J Psychiatry. 2010;44:410-28 pubmed publisher
    ..There is a paucity of systemic, well-conducted trials on the use of pharmacological agents in the management of PDD, and more research in this area is warranted. ..