Experts and Doctors on histones in Moscow, Russia
Locale: Moscow, Russia
Shaytan A, Armeev G, Goncearenco A, Zhurkin V, Landsman D, Panchenko A. Coupling between Histone Conformations and DNA Geometry in Nucleosomes on a Microsecond Timescale: Atomistic Insights into Nucleosome Functions. J Mol Biol. 2016;428:221-237 pubmed publisher
..We discuss the implications of the observed results on the nucleosome function and compare our results to different experimental studies. ..
Dmitriev R, Shakhparonov M, Pestov N. Structure and function of MYST1 histone acetyltransferase in the interactome of animal cells. Biochemistry (Mosc). 2008;73:839-52 pubmed
..In the present review, we examine novel data about functional composition and mechanisms of MYST1-containing complexes. Interplay between MYST1 and other components of the animal cell interactome is also discussed. ..
Ioudinkova E, Barat A, Pichugin A, Markova E, Sklyar I, Pirozhkova I, et al
. Distinct distribution of ectopically expressed histone variants H2A.Bbd and MacroH2A in open and closed chromatin domains. PLoS ONE. 2012;7:e47157 pubmed publisher
..1 and H2A.Bbd histone variants were present and often colocalized. Genomic distribution of macro H2A and H2A.Bbd does not follow any simple rule and is drastically different in open and closed genomic domains. ..
Gavrilov A, Gushchanskaya E, Strelkova O, Zhironkina O, Kireev I, Iarovaia O, et al
. Disclosure of a structural milieu for the proximity ligation reveals the elusive nature of an active chromatin hub. Nucleic Acids Res. 2013;41:3563-75 pubmed publisher
..The finding does not compromise the 3C protocol but allows the consideration of an active chromatin hub as a folded chromatin domain or a nuclear compartment rather than a rigid complex of regulatory elements. ..
Slesarev A, Belova G, Kozyavkin S, Lake J. Evidence for an early prokaryotic origin of histones H2A and H4 prior to the emergence of eukaryotes. Nucleic Acids Res. 1998;26:427-30 pubmed
..These results imply an early divergence within the histone gene family prior to the emergence of eukaryotes and may represent an evolutionary step leading to eukaryotic histones...
Kantidze O, Iarovaia O, Razin S. Assembly of nuclear matrix-bound protein complexes involved in non-homologous end joining is induced by inhibition of DNA topoisomerase II. J Cell Physiol. 2006;207:660-7 pubmed
..Thus, inhibition of topoisomerase II activity triggers assembly of NHEJ complexes at the nuclear matrix...
Krajewski W, Vassiliev O. Histone acetylation facilitates association of nucleosomes with SET domain of ALL-1 methyltransferase in vitro. Biochem Biophys Res Commun. 2010;397:112-6 pubmed publisher
Musinova Y, Lisitsyna O, Golyshev S, Tuzhikov A, Polyakov V, Sheval E. Nucleolar localization/retention signal is responsible for transient accumulation of histone H2B in the nucleolus through electrostatic interactions. Biochim Biophys Acta. 2011;1813:27-38 pubmed publisher
..Though these interactions are non-specific, the functionally unrelated retention of a protein can increase the probability of its interaction with specific and functionally related binding sites. ..
Ioudinkova E, Ulianov S, Bunina D, Iarovaia O, Gavrilov A, Razin S. The inactivation of the ? gene in chicken erythroblasts of adult lineage is not mediated by packaging of the embryonic part of the ?-globin gene domain into a repressive heterochromatin-like structure. Epigenetics. 2011;6:1481-8 pubmed publisher
..This conclusion is supported by the demonstration that in chicken erythroblasts of adult lineage, the embryonal and adult segments of the ?-globin gene domain show similar elevated sensitivities to DNase I...