Experts and Doctors on plasmids in Warsaw, Masovian Voivodeship, Poland


Locale: Warsaw, Masovian Voivodeship, Poland
Topic: plasmids

Top Publications

  1. Aleksandrzak Piekarczyk T, Koryszewska Bagińska A, Grynberg M, Nowak A, Cukrowska B, Kozakova H, et al. Genomic and Functional Characterization of the Unusual pLOCK 0919 Plasmid Harboring the spaCBA Pili Cluster in Lactobacillus casei LOCK 0919. Genome Biol Evol. 2015;8:202-17 pubmed publisher
    ..casei LOCK 0919 became the dominant strain and persisted there for at least 48 days. ..
  2. Baraniak A, Izdebski R, Fiett J, Gawryszewska I, Bojarska K, Herda M, et al. NDM-producing Enterobacteriaceae in Poland, 2012-14: inter-regional outbreak of Klebsiella pneumoniae ST11 and sporadic cases. J Antimicrob Chemother. 2016;71:85-91 pubmed publisher
    ..The largest NDM outbreak in a non-endemic country has been observed, being an alarming phenomenon in resistance epidemiology in Poland. ..
  3. Gniadkowski M, Palucha A, Grzesiowski P, Hryniewicz W. Outbreak of ceftazidime-resistant Klebsiella pneumoniae in a pediatric hospital in Warsaw, Poland: clonal spread of the TEM-47 extended-spectrum beta-lactamase (ESBL)-producing strain and transfer of a plasmid carrying the SHV-5-like ESBL-encoding ge. Antimicrob Agents Chemother. 1998;42:3079-85 pubmed
    ..The data presented here exemplify the complexity of the epidemiological situation concerning ESBL producers typical for large Polish hospitals, in which no ESBL-monitoring programs were in place prior to 1995. ..
  4. Ciok A, Dziewit L, Grzesiak J, Budzik K, Górniak D, Zdanowski M, et al. Identification of miniature plasmids in psychrophilic Arctic bacteria of the genus Variovorax. FEMS Microbiol Ecol. 2016;92:fiw043 pubmed publisher
    ..The miniature plasmids share no similarity with known sequences present in the databases. In silico and experimental analyses identified conserved DNA regions essential for the initiation of replication of these replicons. ..
  5. Obarska Kosinska A, Taylor J, Callow P, Orlowski J, Bujnicki J, Kneale G. HsdR subunit of the type I restriction-modification enzyme EcoR124I: biophysical characterisation and structural modelling. J Mol Biol. 2008;376:438-52 pubmed publisher
    ..The model reveals an ellipsoidal shape of the enzymatic core comprising the N-terminal and central domains, and suggests conformational heterogeneity of the C-terminal region implicated in binding of HsdR to the HsdS-HsdM complex. ..
  6. Kulinska A, Czeredys M, Hayes F, Jagura Burdzy G. Genomic and functional characterization of the modular broad-host-range RA3 plasmid, the archetype of the IncU group. Appl Environ Microbiol. 2008;74:4119-32 pubmed publisher
    ..The putative conjugative-transfer module is highly similar in organization and in its products to transfer regions of certain broad-host-range environmental plasmids. ..
  7. Brzozowska I, Brzozowska K, Zielenkiewicz U. Functioning of the TA cassette of streptococcal plasmid pSM19035 in various Gram-positive bacteria. Plasmid. 2012;68:51-60 pubmed publisher
    ..The broad host range of pSM19035 was confirmed and the copy number of a truncated derivative in transformed strains was determined by real-time qPCR. ..
  8. Piotrowska M, Natorff R, Paszewski A. sconC, a gene involved in the regulation of sulphur metabolism in Aspergillus nidulans, belongs to the SKP1 gene family. Mol Gen Genet. 2000;264:276-82 pubmed
    ..sconC mRNA is present in the sconC3 and sconB2 mutants and the level of the sconC transcript seems not to be significantly regulated by supplementation of the medium with sulphur. ..
  9. Brzozowska I, Zielenkiewicz U. The ClpXP protease is responsible for the degradation of the Epsilon antidote to the Zeta toxin of the streptococcal pSM19035 plasmid. J Biol Chem. 2014;289:7514-23 pubmed publisher
    ..subtilis was analyzed. Additionally, we showed that purified Zeta toxin protects the Epsilon protein from rapid ClpXP-catalyzed degradation. ..

More Information


  1. Gora Sochacka A, Kierzek A, Candresse T, Zagorski W. The genetic stability of potato spindle tuber viroid (PSTVd) molecular variants. RNA. 1997;3:68-74 pubmed
    ..Although it has been observed previously that artificially mutated PSTVd molecules may revert rapidly to the wild-type sequence, this study presents direct evidence for the rapid evolution of naturally occurring PSTVd sequence variants. ..
  2. Mierzejewska J, Kulinska A, Jagura Burdzy G. Functional analysis of replication and stability regions of broad-host-range conjugative plasmid CTX-M3 from the IncL/M incompatibility group. Plasmid. 2007;57:95-107 pubmed
    ..Deletion of the par operon strongly destabilized pCTX-M3 despite the presence of the pemIK toxin-antidote system identical to that on NR1(R100) plasmids. Deletion of the pemIK operon had no effect on plasmid stability...
  3. Bartosik D, Putyrski M, Dziewit L, Malewska E, Szymanik M, Jagiello E, et al. Transposable modules generated by a single copy of insertion sequence ISPme1 and their influence on structure and evolution of natural plasmids of Paracoccus methylutens DM12. J Bacteriol. 2008;190:3306-13 pubmed publisher
    ..This illustrates that TMos may play a significant role in shaping the structure of natural plasmids, which consequently may have a great impact on the evolution of plasmid genomes...
  4. Skowronek K, Kasprzak A. A two-plasmid system for independent genetic manipulation of subunits of homodimeric proteins and selective isolation of chimeric dimers. Anal Biochem. 2002;300:185-91 pubmed
    ..The system is a powerful tool in studies of different aspects of interactions between subunits of the homodimeric proteins since it makes possible separate genetic manipulations on each subunit of the dimer. ..
  5. Fiett J, Baraniak A, Mr wka A, Fleischer M, Drulis Kawa Z, Naumiuk u, et al. Molecular epidemiology of acquired-metallo-beta-lactamase-producing bacteria in Poland. Antimicrob Agents Chemother. 2006;50:880-6 pubmed publisher
    ..All of the data collected in this study revealed that even at this early stage of detection, the epidemiological situation concerning MBL producers in Poland has already been complex and very dynamic...
  6. Dolowy P, Mondzelewski J, Zawadzka R, Baj J, Bartosik D. Cloning and characterization of a region responsible for the maintenance of megaplasmid pTAV3 of Paracoccus versutus UW1. Plasmid. 2005;53:239-50 pubmed
    ..pantotrophus. Basic replicons of the pTAV3-type are able to maintain large bacterial genomes, therefore they appear to be good candidates for the construction of vectors specific for Alphaproteobacteria...
  7. Zienkiewicz M, Kern Zdanowicz I, Carattoli A, Gniadkowski M, Ceg owski P. Tandem multiplication of the IS26-flanked amplicon with the bla(SHV-5) gene within plasmid p1658/97. FEMS Microbiol Lett. 2013;341:27-36 pubmed publisher
    ..The results prompted us to speculate that local DNA structure, especially favorable in p1658/97, might have been responsible for the IS26-bla(SHV-5) multiplication ability...
  8. Sirko A, Zatyka M, Hulanicka M. Identification of the Escherichia coli cysM gene encoding O-acetylserine sulphydrylase B by cloning with mini-Mu-lac containing a plasmid replicon. J Gen Microbiol. 1987;133:2719-25 pubmed
    ..Enzyme assays on transformants carrying the cloned fragments indicated the presence in the latter of the cysA and cysM genes coding for sulphate permease and O-acetylserine sulphydrylase B, respectively. ..
  9. Szymanik M, Welc Faleciak R, Bartosik D, Włodarczyk M. Replication system of plasmid pMTH4 of Paracoccus methylutens DM12 contains an enhancer. Pol J Microbiol. 2006;55:261-70 pubmed
    ..We speculate that this region might constitute a site of binding of plasmid or host-encoded proteins that are able to interact with the origin, which positively regulates the initiation of replication...
  10. Wardak S, Szych J, Zasada A, Gierczynski R. Antibiotic resistance of Campylobacter jejuni and Campylobacter coli clinical isolates from Poland. Antimicrob Agents Chemother. 2007;51:1123-5 pubmed
    ..9% and 13.7% were resistant to ciprofloxacin and tetracycline, respectively. Replacement of Thr86 with Ile in GyrA and a plasmid-borne tet(O) gene were the main resistance mechanisms for fluoroquinolones and tetracycline, respectively...
  11. Dziewit L, Jazurek M, Drewniak L, Baj J, Bartosik D. The SXT conjugative element and linear prophage N15 encode toxin-antitoxin-stabilizing systems homologous to the tad-ata module of the Paracoccus aminophilus plasmid pAMI2. J Bacteriol. 2007;189:1983-97 pubmed publisher
    ..Preliminary data suggest that different cellular proteases are involved in degradation of antitoxins encoded by the loci analyzed...
  12. Zagulski M, Kressler D, Becam A, Rytka J, Herbert C. Mak5p, which is required for the maintenance of the M1 dsRNA virus, is encoded by the yeast ORF YBR142w and is involved in the biogenesis of the 60S subunit of the ribosome. Mol Genet Genomics. 2003;270:216-24 pubmed
    ..8S rRNAs. Thus, Mak5p is involved in the biogenesis of 60S ribosomal subunits. ..
  13. Gniadkowski M, Schneider I, Pa ucha A, Jungwirth R, Mikiewicz B, Bauernfeind A. Cefotaxime-resistant Enterobacteriaceae isolates from a hospital in Warsaw, Poland: identification of a new CTX-M-3 cefotaxime-hydrolyzing beta-lactamase that is closely related to the CTX-M-1/MEN-1 enzyme. Antimicrob Agents Chemother. 1998;42:827-32 pubmed
    ..freundii strain causing routine urinary tract infections has been maintained for a relatively long time in the hospital environment...
  14. Ciesla Z, Jonczyk P, Fijalkowska I. Effect of enhanced synthesis of the epsilon subunit of DNA polymerase III on spontaneous and UV-induced mutagenesis of the Escherichia coli glyU gene. Mol Gen Genet. 1990;221:251-5 pubmed
    ..Finally, we have introduced the pIP13 plasmid carrying the dnaQ gene into the recA1207 strain, which is deficient in the recombinase activity of RecA but constitutive in the protease activity.(ABSTRACT TRUNCATED AT 250 WORDS) ..
  15. Roszczenko P, Radomska K, Wywial E, Collet J, Jagusztyn Krynicka E. A novel insight into the oxidoreductase activity of Helicobacter pylori HP0231 protein. PLoS ONE. 2012;7:e46563 pubmed publisher
    ..pylori cells. Altogether our results show that HP0231 is an oxidoreductase that catalyzes disulfide bond formation in the periplasm. We propose to call it HpDsbA. ..
  16. Kilanczyk E, Graczyk A, Ostrowska H, Kasacka I, Leśniak W, Filipek A. S100A6 is transcriptionally regulated by ?-catenin and interacts with a novel target, lamin A/C, in colorectal cancer cells. Cell Calcium. 2012;51:470-7 pubmed publisher
    ..Our results reveal a novel and important network of relations and interactions between proteins potentially involved in colorectal cancer development and progression. ..
  17. Bartosik D, Baj J, Sochacka M, Piechucka E, Wlodarczyk M. Molecular characterization of functional modules of plasmid pWKS1 of Paracoccus pantotrophus DSM 11072. Microbiology. 2002;148:2847-56 pubmed publisher
    ..Plasmid pWKS1 could replicate in 10 species of Paracoccus and in Agrobacterium tumefaciens, Rhizobium leguminosarum and Rhodobacter sphaeroides, but it could not replicate in E. coli...
  18. Wardal E, Sadowy E, Hryniewicz W. Complex nature of enterococcal pheromone-responsive plasmids. Pol J Microbiol. 2010;59:79-87 pubmed
    ..There are still many aspects of the nature of pheromone plasmids that remain unclear and more detailed studies are needed to understand their uniqueness and complexity...
  19. Lochowska A, Iwanicka Nowicka R, Zaim J, Witkowska Zimny M, Bolewska K, Hryniewicz M. Identification of activating region (AR) of Escherichia coli LysR-type transcription factor CysB and CysB contact site on RNA polymerase alpha subunit at the cysP promoter. Mol Microbiol. 2004;53:791-806 pubmed
  20. Walerych D, Kudla G, Gutkowska M, Wawrzynow B, Muller L, King F, et al. Hsp90 chaperones wild-type p53 tumor suppressor protein. J Biol Chem. 2004;279:48836-45 pubmed
    ..In summary, the results presented in this article state that chaperone activity of Hsp90 is important for the transcriptional activity of genotypically wild-type p53. ..
  21. Hoffman Sommer M, Migdalski A, Rytka J, Kucharczyk R. Multiple functions of the vacuolar sorting protein Ccz1p in Saccharomyces cerevisiae. Biochem Biophys Res Commun. 2005;329:197-204 pubmed
    ..The mechanisms of Ca(2+)-pump-mediated suppression also differ from each other, since the action of Pmr1p, but not Pmc1p, appears to require Arl1p function. ..
  22. Izdebski R, Baraniak A, Bojarska K, Urbanowicz P, Fiett J, Pomorska Wesołowska M, et al. Mobile MCR-1-associated resistance to colistin in Poland. J Antimicrob Chemother. 2016;71:2331-3 pubmed publisher
  23. Papagiannitsis C, Dolejska M, Izdebski R, Giakkoupi P, Skálová A, Chudějová K, et al. Characterisation of IncA/C2 plasmids carrying an In416-like integron with the blaVIM-19 gene from Klebsiella pneumoniae ST383 of Greek origin. Int J Antimicrob Agents. 2016;47:158-62 pubmed publisher
    ..Considering the broad host range of IncA/C2 molecules, it seems that pKP-Gr642, pKP-Gr8143 and pEcl-Gr4873 plasmids might support the diffusion of In416-like integrons among Enterobacteriaceae. ..
  24. Mikiewicz D, Wrobel B, Wegrzyn G, Płucienniczak A. Isolation and characterization of a ColE1-like plasmid from Enterobacter agglomerans with a novel variant of rom gene. Plasmid. 1997;38:210-9 pubmed
    ..Moreover, this plasmid may serve as a source of the new rom-like gene coding for a protein useful in investigation of RNA-protein interactions. A role for the pPIGDM1 plasmid in the host strain is not known. ..
  25. Pluta K, Lefebvre O, Martin N, Smagowicz W, Stanford D, Ellis S, et al. Maf1p, a negative effector of RNA polymerase III in Saccharomyces cerevisiae. Mol Cell Biol. 2001;21:5031-40 pubmed
    ..These results indicate that Maf1p acts as a negative effector of Pol III synthesis. This potential regulator of Pol III transcription is likely conserved since orthologs of Maf1p are present in other eukaryotes, including humans. ..
  26. Bartosik D, Szymanik M, Wysocka E. Identification of the partitioning site within the repABC-type replicon of the composite Paracoccus versutus plasmid pTAV1. J Bacteriol. 2001;183:6234-43 pubmed
    ..versutus when RepA and RepB were delivered in trans, proving that this region has centromere-like activity. Thus, it was demonstrated that repA, repB, and inc2 constitute a functional system for active partitioning of pTAV320...
  27. Jaszczur M, Flis K, Rudzka J, Kraszewska J, Budd M, Polaczek P, et al. Dpb2p, a noncatalytic subunit of DNA polymerase epsilon, contributes to the fidelity of DNA replication in Saccharomyces cerevisiae. Genetics. 2008;178:633-47 pubmed publisher
    ..Our results show that DNA polymerase subunits other than those housing the DNA polymerase and 3' --> 5' exonuclease are essential in controlling the level of spontaneous mutagenesis and genetic stability in yeast cells. ..
  28. Bartosik D, Szymanik M, Baj J. Identification and distribution of insertion sequences of Paracoccus solventivorans. Appl Environ Microbiol. 2003;69:7002-8 pubmed
    ..Phylogenetic analysis of Tnps of the novel ISs and their closest relatives showed their evolutionary relationships and possible directions of lateral transfer between various bacterial hosts...
  29. Grabowska D, Chelstowska A. The ALD6 gene product is indispensable for providing NADPH in yeast cells lacking glucose-6-phosphate dehydrogenase activity. J Biol Chem. 2003;278:13984-8 pubmed
    ..A strain bearing a double ZWF1 ALD6 gene disruption is not viable. Thus, our results indicate the reaction catalyzed by Ald6p as an important source of reducing equivalents in the yeast cells. ..
  30. Karpinski P, Grudniak A, Wolska K. Effect of mutations in dnaK and dnaJ genes on cysteine operon expression in Escherichia coli. Folia Microbiol (Praha). 2002;47:371-4 pubmed
  31. Filipek A, Jastrzebska B, Nowotny M, Kuznicki J. CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family. J Biol Chem. 2002;277:28848-52 pubmed
  32. King F, Wawrzynow A, Hohfeld J, Zylicz M. Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53. EMBO J. 2001;20:6297-305 pubmed
    ..The results presented here provide possible molecular mechanisms that can help to explain the observed in vivo role of molecular chaperones in the stabilization and cellular localization of wild-type and mutant p53 protein. ..
  33. Lobocka M, Hennig J, Wild J, Kłopotowski T. Organization and expression of the Escherichia coli K-12 dad operon encoding the smaller subunit of D-amino acid dehydrogenase and the catabolic alanine racemase. J Bacteriol. 1994;176:1500-10 pubmed
    ..We propose that the high-affinity site, centered 59.5 bp upstream of the main transcription start point, plays a role in cAMP-CRP-mediated activation of dad operon expression in the absence of glucose. ..
  34. Baraniak A, Fiett J, Mr wka A, Walory J, Hryniewicz W, Gniadkowski M. Evolution of TEM-type extended-spectrum beta-lactamases in clinical Enterobacteriaceae strains in Poland. Antimicrob Agents Chemother. 2005;49:1872-80 pubmed publisher
    ..The results of this study clearly demonstrate that the environment of Polish hospitals has been highly favorable for the rapid evolution of ESBLs...
  35. Turowski T, Karkusiewicz I, Kowal J, Boguta M. Maf1-mediated repression of RNA polymerase III transcription inhibits tRNA degradation via RTD pathway. RNA. 2012;18:1823-32 pubmed publisher
    ..These results support a model where inhibition of tRNA transcription leads to stabilization of hypomodified tRNA(Val(AAC)) due to more efficient protection by tRNA-interacting proteins. ..
  36. Górecki R, Koryszewska Bagińska A, Gołebiewski M, Zylińska J, Grynberg M, Bardowski J. Adaptative potential of the Lactococcus lactis IL594 strain encoded in its 7 plasmids. PLoS ONE. 2011;6:e22238 pubmed publisher
    ..g. genes encoding citrate and lactose utilization, oligopeptide transport, restriction-modification system). Moreover, global gene analysis indicated cooperation between plasmid- and chromosome-encoded metabolic pathways. ..
  37. Pietrzak M, Puzianowska Kuznicka M. p53-dependent repression of the human MCL-1 gene encoding an anti-apoptotic member of the BCL-2 family: the role of Sp1 and of basic transcription factor binding sites in the MCL-1 promoter. Biol Chem. 2008;389:383-93 pubmed publisher
    ..We propose a novel, promoter-based mechanism by which p53 down-regulates expression of the antiapoptotic MCL-1 protein. ..
  38. Pyrzynska B, Serrano M, Martinez A C, Kaminska B. Tumor suppressor p53 mediates apoptotic cell death triggered by cyclosporin A. J Biol Chem. 2002;277:14102-8 pubmed
    ..Together, our results suggest that the apoptotic program activated by CsA can be mediated by activation of p53 tumor suppressor and potentiation of its ability to initiate apoptosis. ..
  39. Maciejewska A, Sokołowska B, Nowicki A, Kuśmierek J. The role of AlkB protein in repair of 1,N?-ethenoadenine in Escherichia coli cells. Mutagenesis. 2011;26:401-6 pubmed publisher
    ..coli cells. The observed differences of mutation frequencies in the various mutant strains assayed indicate that Mug glycosylase is also engaged in the repair of ?A, whereas the role the AlkA glycosylase in this repair is negligible. ..
  40. Dziewit L, Dmowski M, Baj J, Bartosik D. Plasmid pAMI2 of Paracoccus aminophilus JCM 7686 carries N,N-dimethylformamide degradation-related genes whose expression is activated by a LuxR family regulator. Appl Environ Microbiol. 2010;76:1861-9 pubmed publisher
    ..To our knowledge, this is the first study to provide insights into the genetic organization and regulation as well as the dissemination in bacteria of genes involved in the enzymatic breakdown of DMF...
  41. Bartosik D, Sochacka M, Baj J. Identification and characterization of transposable elements of Paracoccus pantotrophus. J Bacteriol. 2003;185:3753-63 pubmed
    ..These elements will be of a great value in the design of new genetic tools for paracocci, since only one element (IS1248 of P. denitrificans) has been described so far in this genus...
  42. Szymanik M, Bartosik D, Wlodarczyk M. Genetic organization of the basic replicon of plasmid pMTH4 of a facultatively methylotrophic bacterium Paracoccus methylutens DM12. Curr Microbiol. 2004;48:291-4 pubmed
    ..Our investigations suggest that the stabilizing system of pMTH4 is based on the toxin and antidote principle. ..
  43. Radlinska M, Kondrzycka Dada A, Piekarowicz A, Bujnicki J. Identification of amino acids important for target recognition by the DNA:m5C methyltransferase M.NgoPII by alanine-scanning mutagenesis of residues at the protein-DNA interface. Proteins. 2005;58:263-70 pubmed publisher
  44. Jonczyk P, Nowicka A, Fijałkowska I, Schaaper R, Ciesla Z. In vivo protein interactions within the Escherichia coli DNA polymerase III core. J Bacteriol. 1998;180:1563-6 pubmed
    ..Thus, the mutator phenotype of dnaQ49 may be the result of an altered conformation of the epsilon protein, which leads to altered interactions within the Pol III core. ..
  45. Wardal E, Gawryszewska I, Hryniewicz W, Sadowy E. Abundance and diversity of plasmid-associated genes among clinical isolates of Enterococcus faecalis. Plasmid. 2013;70:329-42 pubmed publisher
    ..In conclusion, there is a big and only partially characterized pool of diverse plasmids in clinical E. faecalis...
  46. Reichert M, Winnicka A, Willems L, Kettmann R, Cantor G. Role of the proline-rich motif of bovine leukemia virus transmembrane protein gp30 in viral load and pathogenicity in sheep. J Virol. 2001;75:8082-9 pubmed
    ..Absence of interactions with the proline-rich motif may prevent or delay tumorigenesis in sheep...
  47. Bartosik D, Baj J, Bartosik A, Wlodarczyk M. Characterization of the replicator region of megaplasmid pTAV3 of Paracoccus versutus and search for plasmid-encoded traits. Microbiology. 2002;148:871-81 pubmed
    ..Using pORI6, it was demonstrated that replication systems related to pTAV3 are also present in the replicons of Paracoccus alcaliphilus JCM 7364, Paracoccus thiocyanatus IAM 12816 and Paracoccus methylutens DM 12...
  48. Dziewit L, Baj J, Szuplewska M, Maj A, Tabin M, Czyzkowska A, et al. Insights into the transposable mobilome of Paracoccus spp. (Alphaproteobacteria). PLoS ONE. 2012;7:e32277 pubmed publisher
  49. Dziewit L, Adamczuk M, Szuplewska M, Bartosik D. DIY series of genetic cassettes useful in construction of versatile vectors specific for Alphaproteobacteria. J Microbiol Methods. 2011;86:166-74 pubmed publisher
    ..coli), which will greatly assist the genetic manipulation of Alphaproteobacteria...
  50. Zaleski P, Wawrzyniak P, Sobolewska A, Mikiewicz D, Wójtowicz Krawiec A, Chojnacka Puchta L, et al. New cloning and expression vector derived from Escherichia coli plasmid pIGWZ12; a potential vector for a two-plasmid expression system. Plasmid. 2012;67:264-71 pubmed publisher
    ..NM_006900.3) or ubi-human growth hormone (ubi-hGH; patent No. WO 2005/066208 A2) cloned in another plasmid. In this system, both ubi-interferon alpha and ubi-human growth hormone were deubiquitinated efficiently in E. coli cells. ..
  51. Dziewit L, Kuczkowska K, Adamczuk M, Radlinska M, Bartosik D. Functional characterization of the type II PamI restriction-modification system derived from plasmid pAMI7 of Paracoccus aminophilus JCM 7686. FEMS Microbiol Lett. 2011;324:56-63 pubmed publisher
    ..This indicates the crucial role of the analyzed R-M system in the stable maintenance of pAMI7, which is, to our knowledge, the first report of 'symbiosis' between a R-M system and a plasmid in the Alphaproteobacteria...
  52. Smorawinska M, Szuplewska M, Zaleski P, Wawrzyniak P, Maj A, Plucienniczak A, et al. Mobilizable narrow host range plasmids as natural suicide vectors enabling horizontal gene transfer among distantly related bacterial species. FEMS Microbiol Lett. 2012;326:76-82 pubmed publisher
    ..g. resistance transposons) among evolutionarily distinct bacterial species. Thus, mobilizable NHR plasmids may play a much more important role in horizontal gene transfer than previously thought...