Experts and Doctors on humans in Nijmegen, Gelderland, Netherlands

Summary

Locale: Nijmegen, Gelderland, Netherlands
Topic: humans

Top Publications

  1. Wanten G, Janssen F, Naber A. Saturated triglycerides and fatty acids activate neutrophils depending on carbon chain-length. Eur J Clin Invest. 2002;32:285-9 pubmed
    ..Besides their (poly)-unsaturated counterparts, saturated triglycerides and fatty acids also activate neutrophils. Carbon chain-length is pivotal in the interaction of fatty acids and triglycerides and cells of the immune system. ..
  2. Ebisch I, van Heerde W, Thomas C, van der Put N, Wong W, Steegers Theunissen R. C677T methylenetetrahydrofolate reductase polymorphism interferes with the effects of folic acid and zinc sulfate on sperm concentration. Fertil Steril. 2003;80:1190-4 pubmed
    ..To determine the frequency of C677T methylenetetrahydrofolate reductase (MTHFR) polymorphism in fertile and subfertile males, and the MTHFR-dependent response of sperm concentration after folic acid and/or zinc sulfate intervention...
  3. Fouraux M, Deneka M, Ivan V, van der Heijden A, Raymackers J, van Suylekom D, et al. Rabip4' is an effector of rab5 and rab4 and regulates transport through early endosomes. Mol Biol Cell. 2004;15:611-24 pubmed
    ..We conclude that rabip4' may coordinate the activities of rab4 and rab5, regulating membrane dynamics in the early endosomal system. ..
  4. Koenen H, Fasse E, Joosten I. IL-15 and cognate antigen successfully expand de novo-induced human antigen-specific regulatory CD4+ T cells that require antigen-specific activation for suppression. J Immunol. 2003;171:6431-41 pubmed
    ..In conclusion, IL-15-expanded, de novo-induced human anergic regulatory CD4(+) T cells are of interest in Ag-specific immunotherapy. ..
  5. Luijendijk M, Van Wijk E, Bischoff A, Krieger E, Huygen P, Pennings R, et al. Identification and molecular modelling of a mutation in the motor head domain of myosin VIIA in a family with autosomal dominant hearing impairment (DFNA11). Hum Genet. 2004;115:149-56 pubmed
  6. van Spronsen D, de Weijer K, Mulders P, de Mulder P. Novel treatment strategies in clear-cell metastatic renal cell carcinoma. Anticancer Drugs. 2005;16:709-17 pubmed
    ..Early clinical results are promising, but their place in the treatment of RCC has to be determined. ..
  7. Ljungkvist A, Bussink J, Kaanders J, van der Kogel A. Dynamics of tumor hypoxia measured with bioreductive hypoxic cell markers. Radiat Res. 2007;167:127-45 pubmed
    ..Therefore, bioreductive exogenous hypoxia markers are promising as tools for development of predictive assays or as tools for early treatment monitoring and validation of potential endogenous hypoxia markers. ..
  8. Berkhout M, Nagtegaal I, Cornelissen S, Dekkers M, van de Molengraft F, Peters W, et al. Chromosomal and methylation alterations in sporadic and familial adenomatous polyposis-related duodenal carcinomas. Mod Pathol. 2007;20:1253-62 pubmed
    ..Furthermore, hypermethylation seems to be a general feature of both FAP-related duodenal carcinomas as well as sporadic duodenal carcinomas with the exception of the PAX6 gene, which is methylated only in FAP-related carcinomas. ..
  9. Kollée L, Cuttini M, Delmas D, Papiernik E, den Ouden A, Agostino R, et al. Obstetric interventions for babies born before 28 weeks of gestation in Europe: results of the MOSAIC study. BJOG. 2009;116:1481-91 pubmed publisher
    ..There are large differences between European regions in obstetric practices at the lower limit of viability and these are related to outcome, especially at 24-25 weeks. ..

More Information

Publications757 found, 100 shown here

  1. Ramakers B, Riksen N, Stal T, Heemskerk S, van den Broek P, Peters W, et al. Dipyridamole augments the antiinflammatory response during human endotoxemia. Crit Care. 2011;15:R289 pubmed publisher
    ..ClinicalTrials (NCT): NCT01091571. ..
  2. Oude Lashof A, Sobel J, Ruhnke M, Pappas P, Viscoli C, Schlamm H, et al. Safety and tolerability of voriconazole in patients with baseline renal insufficiency and candidemia. Antimicrob Agents Chemother. 2012;56:3133-7 pubmed publisher
    ..Intravenous voriconazole formulated with SBECD was effective in patients with moderate or severe renal insufficiency and candidemia and was associated with less acute renal toxicity than amphotericin B/fluconazole. ..
  3. van Haren I, Timmerman H, Potting C, Blijlevens N, Staal J, Nijhuis van der Sanden M. Physical exercise for patients undergoing hematopoietic stem cell transplantation: systematic review and meta-analyses of randomized controlled trials. Phys Ther. 2013;93:514-28 pubmed publisher
    ..The results suggest that recipients of HSCT may benefit from physical exercise. ..
  4. Terwisscha van Scheltinga J, Krabbendam I, Spaanderman M. Differentiating between gestational and chronic hypertension; an explorative study. Acta Obstet Gynecol Scand. 2013;92:312-7 pubmed publisher
    ..Differentiating between chronic or gestational hypertension does not seem to help in establishing the risk for later hypertensive sequelae or intra-uterine growth restriction. ..
  5. Peters H, Laarakkers C, Pickkers P, Masereeuw R, Boerman O, Eek A, et al. Tubular reabsorption and local production of urine hepcidin-25. BMC Nephrol. 2013;14:70 pubmed publisher
    ..Hepcidin-25 is reabsorbed by the renal tubules and increased urine hepcidin-25 levels may reflect a reduction in tubular uptake. Uncoupling of FE of hepcidin-25 and ?(2)m in cardiac surgery patients suggests local production. ..
  6. Mulckhuyse M, Dalmaijer E. Distracted by danger: Temporal and spatial dynamics of visual selection in the presence of threat. Cogn Affect Behav Neurosci. 2016;16:315-24 pubmed publisher
    ..The current findings are interpreted in terms of a neurobiological model of saccade programming. ..
  7. Okkersen K, Monckton D, Le N, Tuladhar A, Raaphorst J, van Engelen B. Brain imaging in myotonic dystrophy type 1: A systematic review. Neurology. 2017;89:960-969 pubmed publisher
    ..Longitudinal studies evaluating spatiotemporal imaging changes are essential. ..
  8. Chussi D, Poelman S, van Heerbeek N. Guillotine vs. classic dissection adenotonsillectomy: What's the ideal technique for children in Tanzania?. Int J Pediatr Otorhinolaryngol. 2017;100:137-140 pubmed publisher
  9. van Kempen L, Meier F, Egeblad M, Kersten Niessen M, Garbe C, Weidle U, et al. Truncation of activated leukocyte cell adhesion molecule: a gateway to melanoma metastasis. J Invest Dermatol. 2004;122:1293-301 pubmed
    ..ALCAM induction could, thus, provide an attractive target for proteolysis as a part of a more complex cellular program that couples growth and migration and facilitates dissemination. ..
  10. Gellekink H, Blom H, van der Linden I, den Heijer M. Molecular genetic analysis of the human dihydrofolate reductase gene: relation with plasma total homocysteine, serum and red blood cell folate levels. Eur J Hum Genet. 2007;15:103-9 pubmed
    ..The 19-bp del/del genotype was associated with a lower plasma tHcy (-14.4% [95% confidence interval: -23.5 to -4.5], P=0.006) compared with the wild-type genotype. This may suggest that intracellular folate levels are affected. ..
  11. Bovenschen H, van de Kerkhof P, van Erp P, Woestenenk R, Joosten I, Koenen H. Foxp3+ regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin. J Invest Dermatol. 2011;131:1853-60 pubmed publisher
    ..These data stress the clinical relevance of Treg differentiation for the perpetuation of chronic inflammatory disease and may pave novel ways for immunotherapy. ..
  12. Nonkes L, van Bussel I, Verheij M, Homberg J. The interplay between brain 5-hydroxytryptamine levels and cocaine addiction. Behav Pharmacol. 2011;22:723-38 pubmed publisher
    ..In addition, 5-HT mediates, to some extent, the aversive effects of cocaine. Difficulties with data interpretation are discussed. ..
  13. Delsing C, Warris A, Bleeker Rovers C. Q fever: still more queries than answers. Adv Exp Med Biol. 2011;719:133-43 pubmed publisher
    ..Doxycycline is the treatment of choice for acute infection. An alternative for young children and pregnant women is cotrimoxazole. Chronic infection requires long term treatment usually with doxycycline combined with hydroxychloroquine...
  14. de Weerth C, Fuentes S, Puylaert P, de Vos W. Intestinal microbiota of infants with colic: development and specific signatures. Pediatrics. 2013;131:e550-8 pubmed publisher
    ..To provide a comprehensive analysis of the fecal microbiota in infants with colic, as compared with control infants, during their first 100 days of life...
  15. ter Huurne N, Lozano Soldevilla D, Onnink M, Kan C, Buitelaar J, Jensen O. Diminished modulation of preparatory sensorimotor mu rhythm predicts attention-deficit/hyperactivity disorder severity. Psychol Med. 2017;47:1947-1956 pubmed publisher
    ..This could explain disruptive motor activity in ADHD. These results provide further evidence that impaired modulation of α band oscillations is involved in the pathogenesis of ADHD. ..
  16. Meij I, Saar K, van den Heuvel L, Nuernberg G, Vollmer M, Hildebrandt F, et al. Hereditary isolated renal magnesium loss maps to chromosome 11q23. Am J Hum Genet. 1999;64:180-8 pubmed
    ..We conclude that this region encompasses a gene, involved in renal magnesium handling, that is mutated in our patients and is different from the gene involved in intestinal magnesium handling. ..
  17. Meis J, Verweij P. Current management of fungal infections. Drugs. 2001;61 Suppl 1:13-25 pubmed
    ..The high acquisition costs of the lipid-associated formulations of amphotericin-B have limited their use. ..
  18. Marr N, Bichet D, Hoefs S, Savelkoul P, Konings I, de Mattia F, et al. Cell-biologic and functional analyses of five new Aquaporin-2 missense mutations that cause recessive nephrogenic diabetes insipidus. J Am Soc Nephrol. 2002;13:2267-77 pubmed
    ..In addition, the reduced single channel water permeability of AQP2-A47V (40%) and AQP2-T125M (25%) might become of therapeutic value when chemical chaperones can be found that restore their routing to the plasma membrane. ..
  19. Vlems F, Diepstra J, Punt C, Ligtenberg M, Cornelissen I, van Krieken J, et al. Detection of disseminated tumour cells in blood and bone marrow samples of patients undergoing hepatic resection for metastasis of colorectal cancer. Br J Surg. 2003;90:989-95 pubmed
    ..The results strongly suggest that the presence of circulating tumour cells in peripheral blood may reflect transient shedding of tumour cells related to large tumour volume. ..
  20. van der Heijden A, Verhaegh G, Jansen C, Schalken J, Witjes J. Effect of hyperthermia on the cytotoxicity of 4 chemotherapeutic agents currently used for the treatment of transitional cell carcinoma of the bladder: an in vitro study. J Urol. 2005;173:1375-80 pubmed
    ..Hyperthermia alone did not cause decreased cell proliferation. Synergism was most prominent with low drug doses and the most potent drug used in this in vitro study was EO9. ..
  21. Claahsen van der Grinten H, Sweep F, Blickman J, Hermus A, Otten B. Prevalence of testicular adrenal rest tumours in male children with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Eur J Endocrinol. 2007;157:339-44 pubmed
    ..The aim of our study was to determine the presence of TART and their influence on gonadal function in childhood...
  22. Koch S, Holland R, Hengstler M, Van Knippenberg A. Body locomotion as regulatory process: stepping backward enhances cognitive control. Psychol Sci. 2009;20:549-50 pubmed publisher
  23. Kamsteeg E, Stoffels M, Tamma G, Konings I, Deen P. Repulsion between Lys258 and upstream arginines explains the missorting of the AQP2 mutant p.Glu258Lys in nephrogenic diabetes insipidus. Hum Mutat. 2009;30:1387-96 pubmed publisher
    ..In conclusion, our data reveal that the RRRxxxKL motif and repulsion between K258 and the arginine-triplet within this motif are the primary cause of missorting of AQP2-E258K in NDI. ..
  24. Jongen P, Sindic C, Carton H, Zwanikken C, Lemmens W, Borm G. Improvement of health-related quality of life in relapsing remitting multiple sclerosis patients after 2 years of treatment with intramuscular interferon-beta-1a. J Neurol. 2010;257:584-9 pubmed publisher
    ..In RRMS patients, 2 years of treatment with intramuscular INFb-1a is associated with an increase in HR-QoL, especially in younger patients with low disability...
  25. Kessels R, Hensken L. Effects of errorless skill learning in people with mild-to-moderate or severe dementia: a randomized controlled pilot study. NeuroRehabilitation. 2009;25:307-12 pubmed publisher
    ..These findings can be extended to the acquisition of tasks that are relevant for everyday-life functioning, having important implications for dementia care. ..
  26. van Beek E, Binkhorst M, de Hoog M, De Groot P, van Dijk A, Schokking M, et al. Exercise performance and activity level in children with transposition of the great arteries treated by the arterial switch operation. Am J Cardiol. 2010;105:398-403 pubmed publisher
  27. Mulders S, van Engelen B, Wieringa B, Wansink D. Molecular therapy in myotonic dystrophy: focus on RNA gain-of-function. Hum Mol Genet. 2010;19:R90-7 pubmed publisher
    ..These developments offer new hope to patients with DM, even though several hurdles still have to be overcome before they can be introduced into clinical practice...
  28. Kalff K, El Mouedden M, Van Egmond J, Veening J, Joosten L, Scheffer G, et al. Pre-treatment with capsaicin in a rat osteoarthritis model reduces the symptoms of pain and bone damage induced by monosodium iodoacetate. Eur J Pharmacol. 2010;641:108-13 pubmed publisher
    ..The present results support the hypothesis that capsaicin-sensitive sensory neurons contribute to bone lesions in the monosodium iodoacetate-induced osteoarthritis rat model...
  29. Mattijssen S, Hinson E, Onnekink C, Hermanns P, Zabel B, Cresswell P, et al. Viperin mRNA is a novel target for the human RNase MRP/RNase P endoribonuclease. Cell Mol Life Sci. 2011;68:2469-80 pubmed publisher
    ..This is the first study providing direct evidence for the cleavage of a mRNA by RNase MRP/RNase P in human cells. Implications for the involvement in the pathophysiology of CHH are discussed. ..
  30. Arts R, Joosten L, Dinarello C, Kullberg B, Van der Meer J, Netea M. TREM-1 interaction with the LPS/TLR4 receptor complex. Eur Cytokine Netw. 2011;22:11-4 pubmed publisher
    ..These data are in line with the TLR4-TREM1 co-localization in human neutrophils and suggests that, at least some of the biological effects of TREM-1 may be due to its interaction with the TLR4/LPS-receptor complex. ..
  31. Kleinnijenhuis J, Oosting M, Plantinga T, Van der Meer J, Joosten L, Crevel R, et al. Autophagy modulates the Mycobacterium tuberculosis-induced cytokine response. Immunology. 2011;134:341-8 pubmed publisher
  32. Muselaers C, Stillebroer A, Desar I, Boers Sonderen M, van Herpen C, de Weijert M, et al. Tyrosine kinase inhibitor sorafenib decreases 111In-girentuximab uptake in patients with clear cell renal cell carcinoma. J Nucl Med. 2014;55:242-7 pubmed publisher
    ..These results indicate that the efficacy of antibody-mediated treatment or diagnosis modalities is hampered by TKI treatment. ..
  33. Kochunov P, Jahanshad N, Marcus D, Winkler A, Sprooten E, Nichols T, et al. Heritability of fractional anisotropy in human white matter: a comparison of Human Connectome Project and ENIGMA-DTI data. Neuroimage. 2015;111:300-11 pubmed publisher
    ..Uniquely, the measurements of additive genetic contribution performed in this study can be repeated using online genetic analysis tools provided by the HCP ConnectomeDB web application. ..
  34. Schrans D, Avonts D, Christiaens T, Willems S, de Smet K, van Boven K, et al. The search for person-related information in general practice: a qualitative study. Fam Pract. 2016;33:95-9 pubmed publisher
    ..The PeRI classes we identified might form the basis of a new contextual classification mainly for research purposes. This might help to create evidence of the person-centredness of general practice. ..
  35. Bongers E, Shelton L, Milatz S, Verkaart S, Bech A, Schoots J, et al. A Novel Hypokalemic-Alkalotic Salt-Losing Tubulopathy in Patients with CLDN10 Mutations. J Am Soc Nephrol. 2017;28:3118-3128 pubmed publisher
    ..These data suggest that pathogenic CLDN10 mutations affect TAL paracellular ion transport and cause a novel tight junction disease characterized by a non-BS, non-GS autosomal recessive hypokalemic-alkalotic salt-losing phenotype. ..
  36. Staals R, Bronkhorst A, Schilders G, Slomovic S, Schuster G, Heck A, et al. Dis3-like 1: a novel exoribonuclease associated with the human exosome. EMBO J. 2010;29:2358-67 pubmed publisher
    ..Taken together, these data indicate that hDis3L1 is a novel exosome-associated exoribonuclease in the cytoplasm of human cells. ..
  37. Balemans M, Kasri N, Kopanitsa M, Afinowi N, Ramakers G, Peters T, et al. Hippocampal dysfunction in the Euchromatin histone methyltransferase 1 heterozygous knockout mouse model for Kleefstra syndrome. Hum Mol Genet. 2013;22:852-66 pubmed publisher
    ..These data demonstrate that Ehmt1 haploinsufficiency in mice leads to learning deficits and synaptic dysfunction, providing a possible mechanism for the ID phenotype in patients with KS. ..
  38. Van den Wijngaard A, Pijpers M, Joosten P, Roelofs J, van Zoelen E, Olijve W. Functional characterization of two promoters in the human bone morphogenetic protein-4 gene. J Bone Miner Res. 1999;14:1432-41 pubmed
    ..Since various human diseases can be linked directly to aberrant expression of BMP genes, the present findings are of great importance in attempts to develop strategies for therapeutic interference with such diseases. ..
  39. De Leenheer E, Oudesluijs G, Kuijpers Jagtman A, Rappold G, Sengers R, Cremers C. Congenital conductive hearing loss in dyschondrosteosis. Ann Otol Rhinol Laryngol. 2003;112:153-8 pubmed
    ..In our patient, exploratory tympanotomy revealed ankylosis of the stapes and a malformed incus. A substantial gain in hearing threshold was obtained by a stapedectomy in combination with a malleovestibulopexy...
  40. Doerwald L, van Genesen S, Onnekink C, Marin Vinader L, de Lange F, de Jong W, et al. The effect of alphaB-crystallin and Hsp27 on the availability of translation initiation factors in heat-shocked cells. Cell Mol Life Sci. 2006;63:735-43 pubmed
  41. Ferwerda G, Kramer M, de Jong D, Piccini A, Joosten L, Devesaginer I, et al. Engagement of NOD2 has a dual effect on proIL-1beta mRNA transcription and secretion of bioactive IL-1beta. Eur J Immunol. 2008;38:184-91 pubmed
    ..This demonstrates that both caspase-1-dependent and -independent mechanisms are involved in the synergy between NOD2 and TLR. ..
  42. Krapels I, Raijmakers Eichhorn J, Peters W, Roelofs H, Ras F, Steegers Theunissen R. The I,105V polymorphism in glutathione S-transferase P1, parental smoking and the risk for nonsyndromic cleft lip with or without cleft palate. Eur J Hum Genet. 2008;16:358-66 pubmed
    ..Although of borderline significance, these results may underline the importance of smoking cessation in the periconception period for the prevention of CL/P in future generations. ..
  43. Spies P, Melis R, Sjögren M, Rikkert M, Verbeek M. Cerebrospinal fluid alpha-synuclein does not discriminate between dementia disorders. J Alzheimers Dis. 2009;16:363-9 pubmed publisher
    ..We conclude that in clinically diagnosed patients, alpha-synuclein does not appear to be a useful biomarker for the differentiation between DLB and other types of dementia...
  44. Vassen L, Khandanpour C, Ebeling P, van der Reijden B, Jansen J, Mahlmann S, et al. Growth factor independent 1b (Gfi1b) and a new splice variant of Gfi1b are highly expressed in patients with acute and chronic leukemia. Int J Hematol. 2009;89:422-430 pubmed publisher
  45. Löwik M, Groenen P, Levtchenko E, Monnens L, van den Heuvel L. Molecular genetic analysis of podocyte genes in focal segmental glomerulosclerosis--a review. Eur J Pediatr. 2009;168:1291-304 pubmed publisher
    ..In summary, this review updates the current knowledge of genetic causes of congenital and childhood nephrotic syndrome and provides new insights into mechanisms of glomerular dysfunction. ..
  46. Hannink J, van Helvoort H, Dekhuijzen P, Heijdra Y. Dynamic hyperinflation during daily activities: does COPD global initiative for chronic obstructive lung disease stage matter?. Chest. 2010;137:1116-21 pubmed publisher
    ..Dynamic hyperinflation occurs independent of GOLD stage during real-life daily activities. The combination of static and dynamic hyperinflation, however, increases with increasing airflow obstruction. ..
  47. Los E, Deen P, Robben J. Potential of nonpeptide (ant)agonists to rescue vasopressin V2 receptor mutants for the treatment of X-linked nephrogenic diabetes insipidus. J Neuroendocrinol. 2010;22:393-9 pubmed publisher
    ..This makes V2R-specific cell-permeable agonists very promising therapeutics for NDI as a result of misfolded V2R receptors...
  48. Pasker de Jong P, Zielhuis G, van Gelder M, Pellegrino A, Gabreëls F, Eskes T. Antihypertensive treatment during pregnancy and functional development at primary school age in a historical cohort study. BJOG. 2010;117:1080-6 pubmed publisher
    ..Further studies with appropriate sample sizes are warranted to determine the long-term effects of antihypertensive medications. ..
  49. Heins M, Knoop H, Prins J, Stulemeijer M, Van der Meer J, Bleijenberg G. Possible detrimental effects of cognitive behaviour therapy for chronic fatigue syndrome. Psychother Psychosom. 2010;79:249-56 pubmed publisher
    ..The aim of this study is to examine the frequency and severity of symptom deterioration during CBT for CFS...
  50. Bodar E, Simon A, Van der Meer J. Effects of the histone deacetylase inhibitor ITF2357 in autoinflammatory syndromes. Mol Med. 2011;17:363-8 pubmed publisher
    ..In conclusion, ITF2357 monotherapy was able to induce partial response only in patients with Schnitzler syndrome and no response in patients with HIDS. ..
  51. Tsai J, Knoblich G, Sebanz N. On the inclusion of externally controlled actions in action planning. J Exp Psychol Hum Percept Perform. 2011;37:1407-19 pubmed publisher
    ..Implications of these findings for theories of perception-action links and object processing are discussed. ..
  52. Geurts S, de Vegt F, van Altena A, Tjan Heijnen V, Massuger L, Adang E, et al. Impact of routine follow-up examinations on life expectancy in ovarian cancer patients: a simulation study. Int J Gynecol Cancer. 2012;22:1150-7 pubmed publisher
    ..Routine follow-up in ovarian cancer patients is not expected to improve the life expectancy. The timing of detection of recurrent ovarian cancer is immaterial until markedly improved treatment options become available. ..
  53. Costessi A, Mahrour N, Sharma V, Stunnenberg R, Stoel M, Tijchon E, et al. The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME. PLoS ONE. 2012;7:e42822 pubmed publisher
    ..Moreover, EKC subunits associate with PRAME target sites on chromatin. Our data reveal a novel link between the oncoprotein PRAME and the conserved EKC complex and support a role for both complexes in the same pathways. ..
  54. Ten Broek R, Strik C, Issa Y, Bleichrodt R, van Goor H. Adhesiolysis-related morbidity in abdominal surgery. Ann Surg. 2013;258:98-106 pubmed publisher
    ..To determine the incidence of bowel injury in operations requiring adhesiolysis and to assess the impact of adhesiolysis on the incidence of surgical complications, postoperative morbidity, and costs...
  55. Bons D, van den Broek E, Scheepers F, Herpers P, Rommelse N, Buitelaar J, et al. Motor, emotional, and cognitive empathy in children and adolescents with autism spectrum disorder and conduct disorder. J Abnorm Child Psychol. 2013;41:425-43 pubmed publisher
  56. Gielissen M, Prins J, Knoop H, Verhagen S, Bleijenberg G. Pictorial Representation of Self and Illness Measure (PRISM): a graphic instrument to assess suffering in fatigued cancer survivors. Psychol Assess. 2013;25:658-63 pubmed publisher
    ..No change of SIS-cancer was found. The PRISM seems to be a valuable tool in fatigue research and clinical practice. ..
  57. Willemsen M, Nijhof B, Fenckova M, Nillesen W, Bongers E, Castells Nobau A, et al. GATAD2B loss-of-function mutations cause a recognisable syndrome with intellectual disability and are associated with learning deficits and synaptic undergrowth in Drosophila. J Med Genet. 2013;50:507-14 pubmed publisher
    ..Our results in Drosophila suggest that GATAD2B is required directly in neurones for normal cognitive performance and synapse development. ..
  58. Tarantini G, Brener S, Barioli A, Gratta A, Parodi G, Rossini R, et al. Impact of baseline hemorrhagic risk on the benefit of bivalirudin versus unfractionated heparin in patients treated with coronary angioplasty: a meta-regression analysis of randomized trials. Am Heart J. 2014;167:401-412.e6 pubmed publisher
    ..Bivalirudin reduced major and minor bleeding across the entire bleeding risk spectrum. Bivalirudin significantly reduces major and minor bleeding regardless of the estimated baseline hemorrhagic risk. ..
  59. Schepens M, Lutomski J, Bruce I, Olde Rikkert M, Lawlor B. Reliability and Validity of the International Dementia Alliance Schedule for the Assessment and Staging of Care in Ireland. Am J Geriatr Psychiatry. 2016;24:297-300 pubmed publisher
    ..56). This study confirmed that the IDEAL schedule is a valid and reliable instrument in the Irish population and further supports the international use of the IDEAL schedule. ..
  60. Porter J, de Witte T, Cappellini M, Gattermann N. New insights into transfusion-related iron toxicity: Implications for the oncologist. Crit Rev Oncol Hematol. 2016;99:261-71 pubmed publisher
    ..Knowledge gained from managing transfusional iron overload in inherited anemias may be translated to general oncology, with potential for improved patient outcomes. ..
  61. Bartels D, van Laarhoven A, Stroo M, Hijne K, Peerdeman K, Donders A, et al. Minimizing nocebo effects by conditioning with verbal suggestion: A randomized clinical trial in healthy humans. PLoS ONE. 2017;12:e0182959 pubmed publisher
    ..The results of the current study indicate that learning via counterconditioning and verbal suggestion represents a promising strategy for diminishing nocebo responses. ..
  62. Sinke R, de Leeuw B, Janssen H, Weghuis D, Suijkerbuijk R, Meloni A, et al. Localization of X chromosome short arm markers relative to synovial sarcoma- and renal adenocarcinoma-associated translocation breakpoints. Hum Genet. 1993;92:305-8 pubmed
    ..In addition, our current breakpoint analysis has resulted in a revision of the regional localization of the proximal Xp marker DXS226. ..
  63. Knoers N, Bongers E, van Beersum S, Lommen E, van Bokhoven H, Hol F. Nail-patella syndrome: identification of mutations in the LMX1B gene in Dutch families. J Am Soc Nephrol. 2000;11:1762-6 pubmed
    ..In addition, evidence of a correlation between other characteristics of the NPS phenotype and specific mutations has not been found...
  64. Figdor C. Molecular characterization of dendritic cells operating at the interface of innate or acquired immunity. Pathol Biol (Paris). 2003;51:61-3 pubmed
    ..ALCAM is linked to the cytoskeleton and might play a role in DC migration. Measurements of cell/cell contacts at single molecular levels using optical traps is a useful tool to investigate intercellular interactions. ..
  65. Jongerius P, van Hulst K, van den Hoogen F, Rotteveel J. The treatment of posterior drooling by botulinum toxin in a child with cerebral palsy. J Pediatr Gastroenterol Nutr. 2005;41:351-3 pubmed
  66. Van Cann E, Oyen W, Koole R, Stoelinga P. Bone SPECT reduces the number of unnecessary mandibular resections in patients with squamous cell carcinoma. Oral Oncol. 2006;42:409-14 pubmed
    ..Inclusion of SPECT in the preoperative assessment of these patients will lead to a considerable reduction of unnecessary mandibular resections...
  67. Bovenschen H, Kop E, van de Kerkhof P, Seyger M. Etanercept-induced lichenoid reaction pattern in psoriasis. J Dermatolog Treat. 2006;17:381-3 pubmed
    ..Discontinuation of the drug resulted in a slow regression of the eruption. It is important to realize that a lichenoid reaction pattern may occur during anti-TNFalpha agent treatment. ..
  68. Hoevenaren I, Wester R, Schrier R, McFann K, Doctor R, Drenth J, et al. Polycystic liver: clinical characteristics of patients with isolated polycystic liver disease compared with patients with polycystic liver and autosomal dominant polycystic kidney disease. Liver Int. 2008;28:264-70 pubmed
    ..The goal of this study was to compare the clinical features of patients with isolated polycystic liver disease (PCLD) with those of patients with polycystic liver and autosomal dominant polycystic kidney disease (ADPKD)...
  69. Deunk J, Brink M, Dekker H, Kool D, van Kuijk C, Blickman J, et al. Routine versus selective computed tomography of the abdomen, pelvis, and lumbar spine in blunt trauma: a prospective evaluation. J Trauma. 2009;66:1108-17 pubmed publisher
    ..Compared with an algorithm with selective CT, an algorithm with routine CT finds substantially more clinically relevant diagnoses, even in patients with unsuspicious clinical examination, normal CR, and normal AUS. ..
  70. van den Boogaard J, Lyimo R, Irongo C, Boeree M, Schaalma H, Aarnoutse R, et al. Community vs. facility-based directly observed treatment for tuberculosis in Tanzania's Kilimanjaro Region. Int J Tuberc Lung Dis. 2009;13:1524-9 pubmed
    ..Treatment success rates were higher in patients who opted for community DOT than in patients who chose facility-based DOT (all cases), and were similar in smear-positive pulmonary TB patients under community or facility-based DOT. ..
  71. Overeem S, van Nues S, van der Zande W, Donjacour C, van Mierlo P, Lammers G. The clinical features of cataplexy: a questionnaire study in narcolepsy patients with and without hypocretin-1 deficiency. Sleep Med. 2011;12:12-8 pubmed publisher
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    ..Under these conditions, however, lexically guided retuning was position independent: It generalized across syllabic positions. Lexical retuning can thus benefit future recognition of particular sounds wherever they appear in words. ..
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    ..The anorectal physiology supported the good functional results. The preliminary results of the close rectal pouch procedure are promising, with good functional results and a low complication rate after 1 year. ..
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    ..This information not only contributes to our understanding of the pathophysiological mechanism of CI and mitochondrial deficiency but also suggests possible targets for cellular intervention strategies. ..
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    ..However, given the complexity of interventions and outcome measures, the literature does not permit firm conclusions about which interventions have these effects. The European Union, the Framework Programme of the European Commission. ..
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    ..Such results provide biological targets for further inquiry because researchers attempt to better characterize decision-making neural circuitry in SZ as a means to discover new pathways for interventions. ..
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    ..Our findings indicate that the clinical spectrum for AIMP1 defects is broader than witnessed so far. ..
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    ..We hereby report that ANXA1 and CALD1 proteins are independent markers for tamoxifen therapy outcome and are associated to fast tumor progression. ..
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    ..001), which is mainly because of the co-occurrence of NIPA1 repeats in 15% of C9orf72 repeat carriers (p = 0.006). ..
  86. van de Glind I, Heinen M, Geense W, Mesters I, Wensing M, Van Achterberg T. Exploring the Range of Lifestyle Interventions Used in Dutch Health Care Practice: A Qualitative Description. Health Promot Pract. 2016;17:235-43 pubmed publisher
    ..Although health care providers use many different interventions, replacing nontested for evidence-based interventions is required. ..
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    ..5 %) seropositive for A/H5 and 123/1105 (11.1 %) seropositive for A/H9]. ..
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    ..Further mutation analyses in males with X-linked mental retardation must prove that RSK4 is indeed a novel MRX gene. ..
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    ..Such a reduction of between-laboratory CVs is an essential requirement for the use of steroid receptor data in multicentre clinical studies...
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    ..It can be concluded that the balanced gap technique results in stable knees and that releases can safely be performed to achieve neutral leg alignment without causing postoperative laxity. ..