Experts and Doctors on female in Nijmegen, Gelderland, Netherlands


Locale: Nijmegen, Gelderland, Netherlands
Topic: female

Top Publications

  1. Hoek P, Schers H, Bronkhorst E, Vissers K, Hasselaar J. The effect of weekly specialist palliative care teleconsultations in patients with advanced cancer -a randomized clinical trial. BMC Med. 2017;15:119 pubmed publisher
    ..The Netherlands National Trial Register", NTR2817 , prospectively registered: March 21, 2011. ..
  2. Gijzel S, van de Leemput I, Scheffer M, Roppolo M, Olde Rikkert M, Melis R. Dynamical Resilience Indicators in Time Series of Self-Rated Health Correspond to Frailty Levels in Older Adults. J Gerontol A Biol Sci Med Sci. 2017;72:991-996 pubmed publisher
    ..By mirroring the dynamical resilience indicators to a frailty index, we delivered a first empirical base to validate and quantify the construct of systemic resilience in older adults in a dynamic way. ..
  3. Andela C, Repping Wuts H, Stikkelbroeck N, Pronk M, Tiemensma J, Hermus A, et al. Enhanced self-efficacy after a self-management programme in pituitary disease: a randomized controlled trial. Eur J Endocrinol. 2017;177:59-72 pubmed publisher
    ..Future research should focus on the refinement and implementation of this SMI into clinical practice. ..
  4. Timmers L, Boons C, Verbrugghe M, van den Bemt B, Van Hecke A, Hugtenburg J. Supporting adherence to oral anticancer agents: clinical practice and clues to improve care provided by physicians, nurse practitioners, nurses and pharmacists. BMC Cancer. 2017;17:122 pubmed publisher
    ..A multidisciplinary approach is recommended in which the role of the pharmacist could be expanded. ..
  5. Lescure D, Schepman S, Batenburg R, Wiegers T, Verbakel E. Preferences for birth center care in the Netherlands: an exploration of ethnic differences. BMC Pregnancy Childbirth. 2017;17:79 pubmed publisher
    ..In particular, higher educated non-Dutch women had a preference for the personalized care that could be offered by this new birth center. ..
  6. McKay J, Hung R, Han Y, Zong X, Carreras Torres R, Christiani D, et al. Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Nat Genet. 2017;49:1126-1132 pubmed publisher
    ..Other loci include genes such as a cholinergic nicotinic receptor, CHRNA2, and the telomere-related genes OFBC1 and RTEL1. Further exploration of the target genes will continue to provide new insights into the etiology of lung cancer...
  7. Flak J, Arble D, Pan W, Patterson C, Lanigan T, Goforth P, et al. A leptin-regulated circuit controls glucose mobilization during noxious stimuli. J Clin Invest. 2017;127:3103-3113 pubmed publisher
    ..Thus, decreased leptin action on PAG LepRb neurons augments the autonomic response to noxious stimuli, ensuring sufficient glucose mobilization during periods of acute demand in the face of diminished energy stores. ..
  8. Mocking R, Nap T, Westerink A, Assies J, Vaz F, Koeter M, et al. Biological profiling of prospective antidepressant response in major depressive disorder: Associations with (neuro)inflammation, fatty acid metabolism, and amygdala-reactivity. Psychoneuroendocrinology. 2017;79:84-92 pubmed publisher
    ..Future studies in independent samples are needed to replicate and test the clinical applicability of these biological predictors for treatment response to result in a precision/personalized medicine approach for treatment. ..
  9. Roording Ragetlie S, Klip H, Buitelaar J, Slaats Willemse D. Working memory training in children with neuropsychiatric disorders and mild to borderline intellectual functioning, the role of coaching; a double-blind randomized controlled trial. BMC Psychiatry. 2017;17:114 pubmed publisher
    ..Dutch Trial Register. NTR5223 . Registration date 06-09-2015. ..

More Information

Publications150 found, 100 shown here

  1. Nies M, Dekker B, Sulkers E, Huizinga G, Klein Hesselink M, Maurice Stam H, et al. Psychosocial development in survivors of childhood differentiated thyroid carcinoma: a cross-sectional study. Eur J Endocrinol. 2018;178:215-223 pubmed publisher
    ..Social development was slightly more favorable in DTC survivors than in other CCS, but was similar on autonomy and psychosexual domains. ..
  2. van Nierop J, van Trier D, van der Burgt I, Draaisma J, Mylanus E, Snik A, et al. Cochlear implantation and clinical features in patients with Noonan syndrome and Noonan syndrome with multiple lentigines caused by a mutation in PTPN11. Int J Pediatr Otorhinolaryngol. 2017;97:228-234 pubmed publisher
    ..Otological and audiological examinations in NS and NSML are important, and for those with severe hearing loss, the CI surgery improved the audiological outcome regardless of age. ..
  3. Chussi D, Poelman S, van Heerbeek N. Guillotine vs. classic dissection adenotonsillectomy: What's the ideal technique for children in Tanzania?. Int J Pediatr Otorhinolaryngol. 2017;100:137-140 pubmed publisher
  4. Abrahams H, Gielissen M, Donders R, Goedendorp M, van der Wouw A, Verhagen C, et al. The efficacy of Internet-based cognitive behavioral therapy for severely fatigued survivors of breast cancer compared with care as usual: A randomized controlled trial. Cancer. 2017;123:3825-3834 pubmed publisher
    ..Cancer 2017;123:3825-34. © 2017 American Cancer Society. ..
  5. Hoa L, Tuan N, My P, Huong T, Chi N, Hau Thu T, et al. Assessing evidence for avian-to-human transmission of influenza A/H9N2 virus in rural farming communities in northern Vietnam. J Gen Virol. 2017;98:2011-2016 pubmed publisher
    ..5 %) seropositive for A/H5 and 123/1105 (11.1 %) seropositive for A/H9]. ..
  6. Maas R, Iwanicka Pronicka K, Kalkan Ucar S, Alhaddad B, AlSayed M, Al Owain M, et al. Progressive deafness-dystonia due to SERAC1 mutations: A study of 67 cases. Ann Neurol. 2017;82:1004-1015 pubmed publisher
    ..MEGDHEL syndrome is a progressive deafness-dystonia syndrome with frequent and reversible neonatal liver involvement and a strikingly homogenous course of disease. Ann Neurol 2017;82:1004-1015. ..
  7. Wang J, Xu Monette Z, Jabbar K, Shen Q, Manyam G, Tzankov A, et al. AKT Hyperactivation and the Potential of AKT-Targeted Therapy in Diffuse Large B-Cell Lymphoma. Am J Pathol. 2017;187:1700-1716 pubmed publisher
    ..This study demonstrates the clinical and therapeutic implications of AKT hyperactivation in DLBCL and suggests that AKT inhibitors need to be combined with other targeted agents for DLBCL to achieve optimal clinical efficacy. ..
  8. Leijendekkers R, Hinte G, Sman A, Staal J, Nijhuis van der Sanden M, Hoogeboom T. Clinimetric properties of hip abduction strength measurements obtained using a handheld dynamometer in individuals with a lower extremity amputation. PLoS ONE. 2017;12:e0179887 pubmed publisher
    ..HHD-technique 2 is a test-retest reproducible and valid measuring technique The technique may be further optimised by the use of an external device to stabilise the HHD. ..
  9. van Dijk A, Donkervoort S, Laméris W, de Vries E, Eijsbouts Q, Vrouenraets B, et al. Short- and Long-Term Outcomes after a Reconstituting and Fenestrating Subtotal Cholecystectomy. J Am Coll Surg. 2017;225:371-379 pubmed publisher
    ..The choice for reconstituting or fenestrating STC depends on intraoperative conditions and both techniques are associated with specific complications. ..
  10. Khetarpal S, Zeng X, Millar J, Vitali C, Somasundara A, Zanoni P, et al. A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels. Nat Med. 2017;23:1086-1094 pubmed publisher
    ..This protective mechanism has the potential to be exploited as a new therapeutic approach to reduce apoC-III levels and circulating TRL burden. ..
  11. Stone W, Sawa P, Lanke K, Rijpma S, Oriango R, Nyaurah M, et al. A Molecular Assay to Quantify Male and Female Plasmodium falciparum Gametocytes: Results From 2 Randomized Controlled Trials Using Primaquine for Gametocyte Clearance. J Infect Dis. 2017;216:457-467 pubmed publisher
    ..The early sterilizing effects of PQ may not be explained by the preferential clearance of male gametocytes and may be due to an effect on gametocyte fitness. ..
  12. Coebergh van den Braak R, Sieuwerts A, Kandimalla R, Lalmahomed Z, Bril S, van Galen A, et al. High mRNA expression of splice variant SYK short correlates with hepatic disease progression in chemonaive lymph node negative colon cancer patients. PLoS ONE. 2017;12:e0185607 pubmed publisher
    ..This association could however not be confirmed in two independent smaller cohorts, suggesting that further extensive validation is needed to confirm the prognostic value of SYK(S) expression in chemonaive LNN colon cancer. ..
  13. Koch S, Holland R, Hengstler M, Van Knippenberg A. Body locomotion as regulatory process: stepping backward enhances cognitive control. Psychol Sci. 2009;20:549-50 pubmed publisher
  14. Poort H, Peters M, Verhagen S, Verhoeven J, van der Graaf W, Knoop H. Time to practice what we preach? Appreciating the autonomy of cancer patients on deciding whether they want to be informed about interventional studies for fatigue. Palliat Med. 2016;30:897-8 pubmed publisher
  15. Savaris R, Fuhrich D, Duarte R, Franik S, Ross J. Antibiotic therapy for pelvic inflammatory disease. Cochrane Database Syst Rev. 2017;4:CD010285 pubmed publisher
    ..In this review, we assessed the optimal treatment regimen for PID...
  16. Eggink F, Mom C, Boll D, Ezendam N, Kruitwagen R, Pijnenborg J, et al. Compliance with adjuvant treatment guidelines in endometrial cancer: room for improvement in high risk patients. Gynecol Oncol. 2017;146:380-385 pubmed publisher
    ..Eagerly awaited results of ongoing randomized clinical trials may provide more definitive guidance regarding adjuvant therapy for high risk endometrial cancer patients. ..
  17. Matzaraki V, Gresnigt M, Jaeger M, Ricaño Ponce I, Johnson M, Oosting M, et al. An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility. PLoS ONE. 2017;12:e0180824 pubmed publisher
    ..By applying this approach to candidaemia, we identified novel susceptibility genes and pathways for candidaemia, and future studies should assess their potential as therapeutic targets. ..
  18. Mastboom M, Verspoor F, Verschoor A, Uittenbogaard D, Nemeth B, Mastboom W, et al. Higher incidence rates than previously known in tenosynovial giant cell tumors. Acta Orthop. 2017;88:688-694 pubmed publisher
    ..Recurrence rate in diffuse type is 2.6 times higher, compared with localized extremity. TGCT is still considered a rare disease; however, it is more common than previously understood. ..
  19. Suttorp C, Desmedt D, Maal T, Breuning K. Facial improvement after mandibular midline distraction and surgically assisted rapid maxillary expansion. Am J Orthod Dentofacial Orthop. 2017;152:523-542 pubmed publisher
    ..Surgical planning in 3 dimensions and the use of a 3-dimensional designed surgical osteotomy guiding wafer should improve the predictability of this treatment approach...
  20. Haycock P, Burgess S, Nounu A, Zheng J, Okoli G, Bowden J, et al. Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study. JAMA Oncol. 2017;3:636-651 pubmed publisher
    ..28-0.61]) and interstitial lung disease (OR, 0.09 [95% CI, 0.05-0.15]). It is likely that longer telomeres increase risk for several cancers but reduce risk for some non-neoplastic diseases, including cardiovascular diseases. ..
  21. ter Huurne N, Lozano Soldevilla D, Onnink M, Kan C, Buitelaar J, Jensen O. Diminished modulation of preparatory sensorimotor mu rhythm predicts attention-deficit/hyperactivity disorder severity. Psychol Med. 2017;47:1947-1956 pubmed publisher
    ..This could explain disruptive motor activity in ADHD. These results provide further evidence that impaired modulation of α band oscillations is involved in the pathogenesis of ADHD. ..
  22. Taghizadeh Armaki M, Hedayati M, Moqarabzadeh V, Ansari S, Mahdavi Omran S, Zarrinfar H, et al. Effect of involved Aspergillus species on galactomannan in bronchoalveolar lavage of patients with invasive aspergillosis. J Med Microbiol. 2017;66:898-904 pubmed publisher
    ..flavus (1.6; P-value=0.031) and the sensitivity of GM lower for A. flavus when compared to A. fumigatus. This finding has implications for diagnosis in hospitals and countries with a high proportion of A. flavus infections. ..
  23. Nibbeling E, Duarri A, Verschuuren Bemelmans C, Fokkens M, Karjalainen J, Smeets C, et al. Exome sequencing and network analysis identifies shared mechanisms underlying spinocerebellar ataxia. Brain. 2017;140:2860-2878 pubmed publisher
    ..Our work links spinocerebellar ataxia to alterations in synaptic transmission and transcription regulation, and identifies these as the main shared mechanisms underlying the genetically diverse spinocerebellar ataxia types...
  24. van Kampen J, van Hooij O, Jansen C, Smit F, van Noort P, Schultz I, et al. miRNA-520f Reverses Epithelial-to-Mesenchymal Transition by Targeting ADAM9 and TGFBR2. Cancer Res. 2017;77:2008-2017 pubmed publisher
    ..Collectively, our results show that miR-520f exerts anti-invasive and antimetastatic effects in vitro and in vivo, warranting further study in clinical settings. Cancer Res; 77(8); 2008-17. ©2017 AACR. ..
  25. Schweren L, Groenman A, von Rhein D, Weeda W, Faraone S, Luman M, et al. Stimulant Treatment Trajectories Are Associated With Neural Reward Processing in Attention-Deficit/Hyperactivity Disorder. J Clin Psychiatry. 2017;78:e790-e796 pubmed publisher
    ..No striatal or structural changes were found. ..
  26. Swider K, Wronka E, Oosterman J, Van Rijn C, Jongsma M. Influence of transient spatial attention on the P3 component and perception of painful and non-painful electric stimuli in crossed and uncrossed hands positions. PLoS ONE. 2017;12:e0182616 pubmed publisher
    ..Our results also suggest that hand position may modulate the strength of the cueing effect, although differences between painful and non-painful stimuli exist. ..
  27. Ritter S, Ferguson S. Happy creativity: Listening to happy music facilitates divergent thinking. PLoS ONE. 2017;12:e0182210 pubmed publisher
  28. Cardoso F, Costa A, Senkus E, Aapro M, Andre F, Barrios C, et al. 3rd ESO-ESMO international consensus guidelines for Advanced Breast Cancer (ABC 3). Breast. 2017;31:244-259 pubmed publisher
  29. van Daalen F, Prins J, Opmeer B, Boermeester M, Visser C, Van Hest R, et al. Effect of an antibiotic checklist on length of hospital stay and appropriate antibiotic use in adult patients treated with intravenous antibiotics: a stepped wedge cluster randomized trial. Clin Microbiol Infect. 2017;23:485.e1-485.e8 pubmed publisher
    ..Low overall checklist completion rates and discordance between checklist-answers and actual provided care might have attenuated the impact of the checklist. ..
  30. Fleuren E, Vlenterie M, van der Graaf W, Hillebrandt Roeffen M, Blackburn J, Ma X, et al. Phosphoproteomic Profiling Reveals ALK and MET as Novel Actionable Targets across Synovial Sarcoma Subtypes. Cancer Res. 2017;77:4279-4292 pubmed publisher
    ..Consequently, our integrated approach has led to the identification of ALK and MET as promising therapeutic targets in SS. Cancer Res; 77(16); 4279-92. ©2017 AACR. ..
  31. Schmitz M, Hannink G, Gardeniers J, Verdonschot N, Slooff T, Schreurs B. Acetabular Reconstructions with Impaction Bone-Grafting and a Cemented Cup in Patients Younger Than 50 Years of Age: A Concise Follow-up, at 27 to 35 Years, of a Previous Report. J Bone Joint Surg Am. 2017;99:1640-1646 pubmed publisher
    ..Cemented impaction bone-grafting is a reasonable long-term solution for demanding primary and revision acetabular reconstructions in young patients with acetabular bone defects...
  32. van Gruting I, Stankiewicz A, Kluivers K, De Bin R, Blake H, Sultan A, et al. Accuracy of Four Imaging Techniques for Diagnosis of Posterior Pelvic Floor Disorders. Obstet Gynecol. 2017;130:1017-1024 pubmed publisher
    ..Because transperineal and endovaginal ultrasonography have good test accuracy and patient acceptability, we suggest these could be used for initial assessment of obstructed defecation syndrome., NCT02239302. ..
  33. Rossato M, Affandi A, Thordardottir S, Wichers C, Cossu M, Broen J, et al. Association of MicroRNA-618 Expression With Altered Frequency and Activation of Plasmacytoid Dendritic Cells in Patients With Systemic Sclerosis. Arthritis Rheumatol. 2017;69:1891-1902 pubmed publisher
  34. Emukule G, Spreeuwenberg P, Chaves S, Mott J, Tempia S, Bigogo G, et al. Estimating influenza and respiratory syncytial virus-associated mortality in Western Kenya using health and demographic surveillance system data, 2007-2013. PLoS ONE. 2017;12:e0180890 pubmed publisher
  35. van den Bosch M, Blom A, van de Loo F, Koenders M, Lafeber F, van den Berg W, et al. Brief Report: Induction of Matrix Metalloproteinase Expression by Synovial Wnt Signaling and Association With Disease Progression in Early Symptomatic Osteoarthritis. Arthritis Rheumatol. 2017;69:1978-1983 pubmed publisher
    ..Wnt signaling in the synovium may potently induce progression of OA via increased production of MMPs. ..
  36. Frielink Loing A, Koning A, Van Lier R. Distinguishing influences of overt and covert attention in anticipatory attentional target tracking. J Vis. 2017;17:3 pubmed publisher
    ..We conclude that covert attention always anticipates motion when keeping track of moving objects, while overt attention is more flexible and its anticipatory nature depends on the tracking task. ..
  37. Pierrache L, Kimchi A, Ratnapriya R, Roberts L, Astuti G, Obolensky A, et al. Whole-Exome Sequencing Identifies Biallelic IDH3A Variants as a Cause of Retinitis Pigmentosa Accompanied by Pseudocoloboma. Ophthalmology. 2017;124:992-1003 pubmed publisher
    ..We observed both phenotypes in 2 siblings carrying the same compound heterozygous variants, which could be explained by variable disease expression and warrants caution when making assertions about genotype-phenotype correlations. ..
  38. van Sluisveld N, Bakhshi Raiez F, de Keizer N, Holman R, Wester G, Wollersheim H, et al. Variation in rates of ICU readmissions and post-ICU in-hospital mortality and their association with ICU discharge practices. BMC Health Serv Res. 2017;17:281 pubmed publisher
    ..Further research is necessary to find factors, which may influence these patient outcomes, in order to improve quality of care. ..
  39. Niehues H, Tsoi L, van der Krieken D, Jansen P, Oortveld M, Rodijk Olthuis D, et al. Psoriasis-Associated Late Cornified Envelope (LCE) Proteins Have Antibacterial Activity. J Invest Dermatol. 2017;137:2380-2388 pubmed publisher
    ..Our findings identify an unknown biological function for LCE3 proteins and suggest a role in epidermal host defense and LCE3B/C-del-mediated psoriasis risk. ..
  40. van Dijk E, Tsonaka R, Klar Mohamad N, Wouters D, de Vries A, de Jong E, et al. Systemic complement activation in central serous chorioretinopathy. PLoS ONE. 2017;12:e0180312 pubmed publisher
  41. Busula A, Bousema T, Mweresa C, Masiga D, Logan J, Sauerwein R, et al. Gametocytemia and Attractiveness of Plasmodium falciparum-Infected Kenyan Children to Anopheles gambiae Mosquitoes. J Infect Dis. 2017;216:291-295 pubmed publisher
    ..falciparum, we show that gametocytes-and not their noninfectious asexual progenitors-induce increased attractiveness of humans to mosquitoes. Our findings therefore support the parasite host manipulation hypothesis. ..
  42. van Aken M, Oosterman J, van Rijn C, Ferdek M, Ruigt G, Peeters B, et al. Pain cognition versus pain intensity in patients with endometriosis: toward personalized treatment. Fertil Steril. 2017;108:679-686 pubmed publisher
    ..In international guidelines on management of women with endometriosis more attention should be paid to the psychological aspects of care. ..
  43. Gonçalves B, Drakeley C, Bousema T. Infectivity of Microscopic and Submicroscopic Malaria Parasite Infections in Areas of Low Malaria Endemicity. J Infect Dis. 2016;213:1516-7 pubmed publisher
  44. van den Bosch S, Dijkema T, Kunze Busch M, Terhaard C, Raaijmakers C, Doornaert P, et al. Uniform FDG-PET guided GRAdient Dose prEscription to reduce late Radiation Toxicity (UPGRADE-RT): study protocol for a randomized clinical trial with dose reduction to the elective neck in head and neck squamous cell carcinoma. BMC Cancer. 2017;17:208 pubmed publisher Identifier: NCT02442375 . ..
  45. van Lieshout J, Fischer I, Kamp M, Donders A, Cornelius J, Steiger H, et al. Subarachnoid Hemorrhage in Germany Between 2010 and 2013: Estimated Incidence Rates Based on a Nationwide Hospital Discharge Registry. World Neurosurg. 2017;104:516-521 pubmed publisher
    ..Rejecting the external validity of studies from countries believed to display an exceptional incidence rates may therefore not be justified. ..
  46. Arts E, Fransen J, den Broeder A, van Riel P, Popa C. Low disease activity (DAS28?3.2) reduces the risk of first cardiovascular event in rheumatoid arthritis: a time-dependent Cox regression analysis in a large cohort study. Ann Rheum Dis. 2017;76:1693-1699 pubmed publisher
    ..Our results strengthen the use of tight control strategies in daily clinical practice to achieve low stable disease activity or remission in patients with RA as soon as possible. ..
  47. Kaal S, Husson O, van Duivenboden S, Jansen R, Manten Horst E, Servaes P, et al. Empowerment in adolescents and young adults with cancer: Relationship with health-related quality of life. Cancer. 2017;123:4039-4047 pubmed publisher
  48. Ravesteijn B, Schachar E, Beekman A, Janssen R, Jeurissen P. Association of Cost Sharing With Mental Health Care Use, Involuntary Commitment, and Acute Care. JAMA Psychiatry. 2017;74:1-9 pubmed publisher
    ..A higher out-of-pocket price for mental health care may lead not only to cost savings but also to negative downstream consequences...
  49. Desar I, Mulder S, Stillebroer A, van Spronsen D, van der Graaf W, Mulders P, et al. The reverse side of the victory: flare up of symptoms after discontinuation of sunitinib or sorafenib in renal cell cancer patients. A report of three cases. Acta Oncol. 2009;48:927-31 pubmed publisher
  50. Holland K, van Gils C, Mann R, Karssemeijer N. Quantification of masking risk in screening mammography with volumetric breast density maps. Breast Cancer Res Treat. 2017;162:541-548 pubmed publisher
    ..022). Differences between BI-RADS and PDV, or BI-RADS and DTMM, are not statistically significant. Measures based on density maps, and in particular PDA, are promising tools to identify women at high risk for a masked cancer. ..
  51. Norman M, Piedvache A, Børch K, Huusom L, Bonamy A, Howell E, et al. Association of Short Antenatal Corticosteroid Administration-to-Birth Intervals With Survival and Morbidity Among Very Preterm Infants: Results From the EPICE Cohort. JAMA Pediatr. 2017;171:678-686 pubmed publisher
    ..Administration-to-birth intervals of antenatal corticosteroids (ANS) vary. The significance of this variation is unclear. Specifically, to our knowledge, the shortest effective administration-to-birth interval is unknown...
  52. de Swart L, Smith A, MacKenzie M, Symeonidis A, Neukirchen J, Mikulenkova D, et al. Cytomorphology review of 100 newly diagnosed lower-risk MDS patients in the European LeukemiaNet MDS (EUMDS) registry reveals a high inter-observer concordance. Ann Hematol. 2017;96:1105-1112 pubmed publisher
    ..Our data show that in general, the inter-observer agreement was high and a very low percentage of misdiagnosed cases had been entered into the EUMDS registry. Further studies including histomorphology are warranted. ..
  53. Richters A, Melis R, van Exel N, Olde Rikkert M, van der Marck M. Perseverance time of informal caregivers for people with dementia: construct validity, responsiveness and predictive validity. Alzheimers Res Ther. 2017;9:26 pubmed publisher
    ..The predictive power of perseverance time scores for living situation exceeds the predictive power of other burden measures and indicates informal care as an important factor for maintaining the patient at home. ..
  54. Rao D, Peitzsch M, Prejbisz A, Hanus K, Fassnacht M, Beuschlein F, et al. Plasma methoxytyramine: clinical utility with metanephrines for diagnosis of pheochromocytoma and paraganglioma. Eur J Endocrinol. 2017;177:103-113 pubmed publisher
    ..9% vs 49.3%). While the benefit of additional measurements of plasma methoxytyramine for the detection of PPGLs is modest, the measurements do assist with positive confirmation of disease and are useful for the detection of HNPGLs. ..
  55. Nijsten J, Leontjevas R, Pat El R, Smalbrugge M, Koopmans R, Gerritsen D. Apathy: Risk Factor for Mortality in Nursing Home Patients. J Am Geriatr Soc. 2017;65:2182-2189 pubmed publisher
    ..001). Apathy was associated with mortality over a 4-month period in NH patients, even when controlling for depression. These data suggest that screening and treatment strategies for apathy should be developed for this patient population. ..
  56. Bonaca M, Storey R, Theroux P, Steg P, Bhatt D, Cohen M, et al. Efficacy and Safety of Ticagrelor Over Time in Patients With Prior MI in PEGASUS-TIMI 54. J Am Coll Cardiol. 2017;70:1368-1375 pubmed publisher
    ..Prevention of Cardiovascular Events in Patients with Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin [PEGASUS]; NCT01225562). ..
  57. Iacozza S, Costa A, Duñabeitia J. What do your eyes reveal about your foreign language? Reading emotional sentences in a native and foreign language. PLoS ONE. 2017;12:e0186027 pubmed publisher
    ..These results reveal that the sympathetic nervous system reacts differently depending on the language context, which in turns suggests a deeper emotional processing when reading in a native compared to a foreign language...
  58. Donk R, Fehlings M, Verhagen W, Arnts H, Groenewoud H, Verbeek A, et al. An assessment of the most reliable method to estimate the sagittal alignment of the cervical spine: analysis of a prospective cohort of 138 cases. J Neurosurg Spine. 2017;26:572-576 pubmed publisher
    ..Clinical trial registration no.: ISRCTN41681847 ( ). ..
  59. Bramswig N, Lüdecke H, Hamdan F, Altmuller J, Beleggia F, Elcioglu N, et al. Heterozygous HNRNPU variants cause early onset epilepsy and severe intellectual disability. Hum Genet. 2017;136:821-834 pubmed publisher
  60. Navarro Schröder T, Haak K, Zaragoza Jimenez N, Beckmann C, Doeller C. Functional topography of the human entorhinal cortex. elife. 2015;4: pubmed publisher
    ..Localising the human homologue of the rodent MEC and LEC has important implications for translating studies on the hippocampo-entorhinal memory system from rodents to humans. ..
  61. Willemsen M, Vissers L, Verbeek M, van Bon B, Geuer S, Gilissen C, et al. Upstream SLC2A1 translation initiation causes GLUT1 deficiency syndrome. Eur J Hum Genet. 2017;25:771-774 pubmed publisher
    ..This finding expands our understanding of the disease mechanisms underlying GLUT1DS and encourages further in-depth analysis of SLC2A1 non-coding regions in patients without variants in the coding region. ..
  62. Poort H, Kaal S, Knoop H, Jansen R, Prins J, Manten Horst E, et al. Prevalence and impact of severe fatigue in adolescent and young adult cancer patients in comparison with population-based controls. Support Care Cancer. 2017;25:2911-2918 pubmed publisher
    ..QoL is significantly affected by severe fatigue, stressing the importance of detection and management of this symptom in those patients affected by a life-changing diagnosis of cancer in late adolescence or young adulthood. ..
  63. Myers K, Mandelstam S, Ramantani G, Rushing E, de Vries B, Koolen D, et al. The epileptology of Koolen-de Vries syndrome: Electro-clinico-radiologic findings in 31 patients. Epilepsia. 2017;58:1085-1094 pubmed publisher
    ..Epilepsy surgery should be undertaken with care given the widespread neuroanatomic abnormalities; however, tumors are a rare, yet important, occurrence. ..
  64. Bokma J, Winter M, Kornaat E, Vliegen H, van Dijk A, van Melle J, et al. Right vEntricular Dysfunction in tEtralogy of Fallot: INhibition of the rEnin-angiotensin-aldosterone system (REDEFINE) trial: Rationale and design of a randomized, double-blind, placebo-controlled clinical trial. Am Heart J. 2017;186:83-90 pubmed publisher
    ..In addition, laboratory measurements, echocardiography, and cardiopulmonary exercise testing are performed. The REDEFINE trial will study the effects of RAAS inhibition with losartan in TOF patients with RV dysfunction. ..
  65. de Jong J, Kluijtmans L, van Amerongen M, Prokop M, Boogaarts H, Meijer F. "On the Spot": The Use of Four-Dimensional Computed Tomography Angiography to Differentiate a True Spot Sign From a Distal Intracranial Aneurysm. World Neurosurg. 2017;105:1037.e9-1037.e12 pubmed publisher
    ..This finding proves the additional value of this relatively new technique, because the detected underlying disorders have different therapeutic consequences in the acute setting. ..
  66. Oosten L, Chamuleau M, Thielen F, de Wreede L, Siemes C, Doorduijn J, et al. Treatment of sporadic Burkitt lymphoma in adults, a retrospective comparison of four treatment regimens. Ann Hematol. 2018;97:255-266 pubmed publisher
    ..These differences may help guide future choice of treatment. ..
  67. Karssemeijer E, Bossers W, Aaronson J, Kessels R, Olde Rikkert M. The effect of an interactive cycling training on cognitive functioning in older adults with mild dementia: study protocol for a randomized controlled trial. BMC Geriatr. 2017;17:73 pubmed publisher
    ..The results of this study may be used for physical and mental activity recommendations in older adults with dementia. The Netherlands National Trial Register NTR5581 . Registered 14 February 2016. ..
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    ..There were no new safety concerns and the rate of progression to AML was low; response to romiplostim was maintained for most patients. ..
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