Genomes and Genes
Experts and Doctors on enzyme activation in Wako, Saitama, Japan
Locale: Wako, Saitama, Japan
Topic: enzyme activation
- Nakanishi K, Maruyama M, Shibata T, Morishima N. Identification of a caspase-9 substrate and detection of its cleavage in programmed cell death during mouse development. J Biol Chem. 2001;276:41237-44 pubmed..Our results show that the specific antibody is useful for in situ detection of caspase-9 activation in programmed cell death. ..
- Kuranaga E, Kanuka H, Igaki T, Sawamoto K, Ichijo H, Okano H, et al. Reaper-mediated inhibition of DIAP1-induced DTRAF1 degradation results in activation of JNK in Drosophila. Nat Cell Biol. 2002;4:705-10 pubmed..Taken together, our results indicate that DIAP1 may modulate cell death by regulating JNK activation through a ubiquitin#150;proteasome pathway. ..
- Endo S, Nairn A, Greengard P, Ito M. Thr123 of rat G-substrate contributes to its action as a protein phosphatase inhibitor. Neurosci Res. 2003;45:79-89 pubmed..These results characterize further the inhibition of PP-1 and PP-2A by phospho-G-substrate, and demonstrate its physiological phosphorylation in rat Purkinje cells. ..
- Nakagawa Y. Artificial analogs of naturally occurring tumor promoters as biochemical tools and therapeutic leads. Biosci Biotechnol Biochem. 2012;76:1262-74 pubmed..This review focuses on artificial analogs of phorbol esters, teleocidins, and aplysiatoxins, and discusses their potential as biochemical tools and therapeutic leads. ..