Experts and Doctors on epithelium in Kobe, Hyōgo, Japan


Locale: Kobe, Hyōgo, Japan
Topic: epithelium

Top Publications

  1. Hirata K, Ajiki T, Okazaki T, Horiuchi H, Fujita T, Kuroda Y. Frequent occurrence of abnormal E-cadherin/beta-catenin protein expression in advanced gallbladder cancers and its association with decreased apoptosis. Oncology. 2006;71:102-10 pubmed
    ..E-cadherin expression might be a useful prognostic marker in this tumor. ..
  2. Ito Y, Arai K, Nozawa R, Yoshida H, Higashiyama T, Takamura Y, et al. S100A10 expression in thyroid neoplasms originating from the follicular epithelium: contribution to the aggressive characteristic of anaplastic carcinoma. Anticancer Res. 2007;27:2679-83 pubmed
    ..3% of these lesions were classified in the high group. These findings suggest that S100A10 and annexin II contribute to the aggressive characteristics of anaplastic carcinoma, while playing a constitutive role in papillary carcinoma. ..
  3. Ohsawa S, Sugimura K, Takino K, Xu T, Miyawaki A, Igaki T. Elimination of oncogenic neighbors by JNK-mediated engulfment in Drosophila. Dev Cell. 2011;20:315-28 pubmed publisher
    ..Our data indicate that JNK-mediated cell engulfment could be an evolutionarily conserved intrinsic tumor-suppression mechanism that eliminates premalignant cells from epithelia. ..
  4. Takemura M, Adachi Yamada T. Cell death and selective adhesion reorganize the dorsoventral boundary for zigzag patterning of Drosophila wing margin hairs. Dev Biol. 2011;357:336-46 pubmed publisher
    ..This may be a common mechanism for geometrically ordered repetitive packing of several types of cells in similarly patterned developmental fields such as the mammalian organ of Corti. ..
  5. Dong B, Kakihara K, Otani T, Wada H, Hayashi S. Rab9 and retromer regulate retrograde trafficking of luminal protein required for epithelial tube length control. Nat Commun. 2013;4:1358 pubmed publisher
    ..In contrast, secretion of many luminal proteins was unaffected, suggesting that retrograde trafficking of a specific class of luminal proteins is a pivotal rate-limiting mechanism for continuous tube length regulation...
  6. Lee S, Morishita Y. Possible roles of mechanical cell elimination intrinsic to growing tissues from the perspective of tissue growth efficiency and homeostasis. PLoS Comput Biol. 2017;13:e1005651 pubmed publisher
  7. Motoyama S, Laoag Fernandez J, Mochizuki S, Yamabe S, Maruo T. Vaginoplasty with Interceed absorbable adhesion barrier for complete squamous epithelialization in vaginal agenesis. Am J Obstet Gynecol. 2003;188:1260-4 pubmed
    ..The purpose of this study was to present our experiences of an innovative surgical approach for vaginal agenesis with the use of Interceed absorbable adhesion barrier (Ethicon) to achieve a satisfactory neovagina...
  8. Umemori M, Takemura M, Maeda K, Ohba K, Adachi Yamada T. Drosophila T-box transcription factor Optomotor-blind prevents pathological folding and local overgrowth in wing epithelium through confining Hh signal. Dev Biol. 2007;308:68-81 pubmed
    ..These are the mechanisms for generating secondary phenotypes when a single signaling factor Omb fails to function. ..
  9. Nakaya Y, Sheng G. Epithelial to mesenchymal transition during gastrulation: an embryological view. Dev Growth Differ. 2008;50:755-66 pubmed publisher

More Information


  1. Sasai Y. Cytosystems dynamics in self-organization of tissue architecture. Nature. 2013;493:318-26 pubmed publisher
  2. Ono K, Kita T, Sato S, O Neill P, Mak S, Paschaki M, et al. FGFR1-Frs2/3 signalling maintains sensory progenitors during inner ear hair cell formation. PLoS Genet. 2014;10:e1004118 pubmed publisher
    ..We suggest that FGF signaling, through the activation of MAP kinase, is necessary for the maintenance of sensory progenitors and commits precursors to sensory cell differentiation in the mammalian cochlea. ..
  3. Wen F, Wang Y, Shibata T. Epithelial Folding Driven by Apical or Basal-Lateral Modulation: Geometric Features, Mechanical Inference, and Boundary Effects. Biophys J. 2017;112:2683-2695 pubmed publisher
    ..The mechanical principles revealed in our model could potentially guide future studies on epithelial folding in diverse systems. ..