Experts and Doctors on local neoplasm recurrence in Tokyo, Japan


Locale: Tokyo, Japan
Topic: local neoplasm recurrence

Top Publications

  1. Sondenaa K, Kubota K, Sano K, Takayama T, Makuuchi M. Successful reconstruction of segmental or subsegmental bile ducts after resection of hilar bile ducts: short- and long-term results. Hepatogastroenterology. 2004;51:1278-81 pubmed
    ..Our technique for reconstructing small bile ducts with mucosa-to-mucosa alignment is considered adequate from the viewpoint of short- and long-term results. ..
  2. Homma Y, Akaza H, Okada K, Yokoyama M, Moriyama N, Usami M, et al. Radical prostatectomy and adjuvant endocrine therapy for prostate cancer with or without preoperative androgen deprivation: Five-year results. Int J Urol. 2004;11:295-303 pubmed
    ..However, it did increase the probability of OCD, which was associated with no clinical relapse during the follow-up. A longer observation is needed to clarify the exact extent of the benefits in terms of survival. ..
  3. Ozawa H, Soma K, Ito M, Ogawa K. Liposarcoma of the retropharyngeal space: report of a case and review of literature. Auris Nasus Larynx. 2007;34:417-21 pubmed
    ..In the present case, functional resection and radiotherapy were performed and proved to be efficacious in that no recurrence was observed for 2 years. ..
  4. Tada K, Nishimura S, Miyagi Y, Takahashi K, Makita M, Iwase T, et al. The effect of an old surgical scar on sentinel node mapping in patients with breast cancer: a report of five cases. Eur J Surg Oncol. 2005;31:840-4 pubmed
    ..In the remaining two cases, no sentinel lymph nodes were identified. An old surgical scar in the breast may cause lymphatic drainage disruption, resulting in abnormal radioactive colloid uptake during SNM. ..
  5. Ohno Y, Nakashima J, Ohori M, Hatano T, Tachibana M. Pretreatment neutrophil-to-lymphocyte ratio as an independent predictor of recurrence in patients with nonmetastatic renal cell carcinoma. J Urol. 2010;184:873-8 pubmed publisher
    ..The combination of T stage and the neutrophil-to-lymphocyte ratio can be used to stratify recurrence risk in patients with nonmetastatic renal cell carcinoma. ..
  6. Matsumoto K, Kikuchi E, Horiguchi Y, Tanaka N, Miyajima A, Nakagawa K, et al. Late recurrence and progression in non-muscle-invasive bladder cancers after 5-year tumor-free periods. Urology. 2010;75:1385-90 pubmed publisher
    ..Finally, some of the high-risk patients experienced late progression with a high degree of malignant behavior, suggesting longer follow-up is needed for each patient. ..
  7. Mun M, Kohno T. Single-stage surgical treatment of synchronous bilateral multiple lung cancers. Ann Thorac Surg. 2007;83:1146-51 pubmed
    ..Single-stage bilateral surgical treatment of SBMLC yielded satisfactory results in our selected patients; however, appearance of new lesions remains a problem. ..
  8. Sugino K, Mimura T, Kameyama K, Iwasaki H, Ito K. Hürthle cell tumor of the thyroid: analysis of 188 cases. World J Surg. 2001;25:1160-3 pubmed
    ..All patients with Hürthle cell tumor should be treated by total lobectomy at least. The outcome of the cancer patients was not as poor as in previous reports. ..
  9. Mori T, Hirota T, Ohashi Y, Kodaira S. Significance of histologic type of primary lesion and metastatic lymph nodes as a prognostic factor in stage III colon cancer. Dis Colon Rectum. 2006;49:982-92 pubmed
    ..In such cases, it is possible for adjuvant chemotherapy to have a deleterious effect, and therefore, it is not recommended. ..

More Information


  1. Hotta K, Fujii T, Saito Y, Matsuda T. Local recurrence after endoscopic resection of colorectal tumors. Int J Colorectal Dis. 2009;24:225-30 pubmed publisher
    ..However, almost all cases of local recurrences could be cured by additional endoscopic resection, so piecemeal resection can be acceptable treatment. ..
  2. Kunitoh H, Kato H, Tsuboi M, Shibata T, Asamura H, Ichinose Y, et al. Phase II trial of preoperative chemoradiotherapy followed by surgical resection in patients with superior sulcus non-small-cell lung cancers: report of Japan Clinical Oncology Group trial 9806. J Clin Oncol. 2008;26:644-9 pubmed publisher
    ..The disease-free and overall survival rates at 3 years were 49% and 61%, respectively; at 5 years, they were 45% and 56%, respectively. This trimodality approach is safe and effective for the treatment of patients with SSTs. ..
  3. Kikuchi E, Fujimoto H, Mizutani Y, Okajima E, Koga H, Hinotsu S, et al. Clinical outcome of tumor recurrence for Ta, T1 non-muscle invasive bladder cancer from the data on registered bladder cancer patients in Japan: 1999-2001 report from the Japanese Urological Association. Int J Urol. 2009;16:279-86 pubmed publisher
    ..Further study with a dataset created from longer follow-up data would be warranted to analyze tumor progression and disease survival. ..
  4. Ito F, Tanaka H, Oi K, Arai H, Sunamori M. [Multiple recurrence of cardiac myxoma in a Carney complex patient 4 years after the first operation]. Kyobu Geka. 2006;59:1159-62 pubmed
    ..All 3 myxomas were successfully resected. Sixteen months after the 2nd operation, she has been doing well without any sign of recurrence of myxoma. ..
  5. Tateishi U, Hasegawa T, Beppu Y, Satake M, Moriyama N. Primary dedifferentiated liposarcoma of the retroperitoneum. Prognostic significance of computed tomography and magnetic resonance imaging features. J Comput Assist Tomogr. 2003;27:799-804 pubmed
    ..Calcification or ossification and first recurrence identified by CT and MR imaging studies are significant adverse prognostic factors in primary dedifferentiated liposarcoma of the retroperitoneum. ..
  6. Mise Y, Imamura H, Hashimoto T, Seyama Y, Aoki T, Hasegawa K, et al. Cohort study of the survival benefit of resection for recurrent hepatic and/or pulmonary metastases after primary hepatectomy for colorectal metastases. Ann Surg. 2010;251:902-9 pubmed publisher
    ..Reresection is the only potentially curative treatment. Stricter indication criteria, especially regarding the number of tumor nodules, can lead to comparable long-term outcomes. ..
  7. Tsunoda A, Shibusawa M, Tanizaki H, Kusano M. Hypogastric nerve preservation does not increase local recurrence after surgical treatment of rectal carcinoma. Hepatogastroenterology. 2004;51:1354-7 pubmed
    ..Hypogastric nerve-preserving operation does not appear to carry an increased risk of local recurrence compared with hypogastric nerve-removing operation after an equivalent follow-up period. ..
  8. Sashide K, Isobe H, Wakumoto Y, Hanazawa K, Fujita K, Fujime M. CA19-9 as a serum marker for poor prognosis in urothelial carcinoma. Urol Int. 2004;72:112-7 pubmed
    ..Serum CA19-9 is thought to serve as a significant marker for advanced cancer and tumors with highly malignant potential and is useful for predicting prognosis of the disease. ..
  9. Tokudome N, Sakamoto G, Sakai T, Sarumaru S, Okuyama N, Hori F, et al. A case of carcinosarcoma of the breast. Breast Cancer. 2005;12:149-53 pubmed
    ..Such tumors are very rare, and there have been no detailed reports of recurrence patterns of carcinosarcoma. Here we report our pathological findings in detail. ..
  10. Shimokawa T, Shibuya M, Kitamura K, Hosomi Y, Hibino S, Ota T, et al. Retrospective analysis of efficacy and safety of amrubicin in refractory and relapsed small-cell lung cancer. Int J Clin Oncol. 2009;14:63-9 pubmed publisher
    ..Further research is warranted to investigate amrubicin treatment for patients with SCLC. ..
  11. Aimoto T, Uchida E, Nakamura Y, Katsuno A, Chou K, Tajiri T, et al. Malignant afferent loop obstruction following pancreaticoduodenectomy: report of two cases. J Nippon Med Sch. 2006;73:226-30 pubmed
    ..In conclusion, the surgical bypass seems to be an effective palliative treatment for afferent loop syndrome after PD. ..
  12. Fukuhara H, Kume H, Suzuki M, Fujimura T, Enomoto Y, Nishimatsu H, et al. Maximum tumor diameter: a simple independent predictor for biochemical recurrence after radical prostatectomy. Prostate Cancer Prostatic Dis. 2010;13:244-7 pubmed publisher
    ..MTD would be a useful tool for predicting BCR, as calculation of MTD is a simple and reliable measure. ..
  13. Matsumoto K, Satoh T, Irie A, Ishii J, Kuwao S, Iwamura M, et al. Loss expression of uroplakin III is associated with clinicopathologic features of aggressive bladder cancer. Urology. 2008;72:444-9 pubmed publisher
  14. Tobinai K, Ishizawa K, Ogura M, Itoh K, Morishima Y, Ando K, et al. Phase II study of oral fludarabine in combination with rituximab for relapsed indolent B-cell non-Hodgkin lymphoma. Cancer Sci. 2009;100:1951-6 pubmed publisher
    ..In conclusion, oral fludarabine in combination with rituximab is a highly effective and convenient therapy for patients with relapsed indolent B-NHL who have mostly been pretreated with rituximab. ..
  15. Yoshimine S, Kikuchi E, Matsumoto K, Ide H, Miyajima A, Nakagawa K, et al. The clinical significance of urine cytology after a radical cystectomy for urothelial cancer. Int J Urol. 2010;17:527-32 pubmed publisher
    ..Urine cytology after RC was not a potent screening tool for the early detection of UTR because of the difficulty in distinguishing the cancer cells from degenerated intestinal epithelial cells in the urinary diversion urine. ..
  16. Nakaya K, Chernov M, Kasuya H, Izawa M, Hayashi M, Kato K, et al. Risk factors for regrowth of intracranial meningiomas after gamma knife radiosurgery: importance of the histopathological grade and MIB-1 index. Minim Invasive Neurosurg. 2009;52:216-21 pubmed publisher
    ..It requires close neuroradiological follow-up and necessitates the search for modified treatment strategies. ..
  17. Hasebe T, Tamura N, Okada N, Hojo T, Akashi Tanaka S, Shimizu C, et al. p53 expression in tumor-stromal fibroblasts is closely associated with the nodal metastasis and outcome of patients with invasive ductal carcinoma who received neoadjuvant therapy. Hum Pathol. 2010;41:262-70 pubmed publisher
  18. Ueda K, Okamoto A, Yamada K, Saito M, Takakura S, Tanaka T, et al. Nonpuerperal inversion of the uterus associated with endometrial cancer: a case report. Int J Clin Oncol. 2006;11:153-5 pubmed
    ..In this article, we present a case of a patient with uterine inversion caused by endometrial cancer that could be diagnosed and treated with surgery. We also discuss the mechanism of onset and present a review of the literature. ..
  19. Shien T, Shimizu C, Seki K, Shibata T, Hojo T, Ando M, et al. Comparison among different classification systems regarding the pathological response of preoperative chemotherapy in relation to the long-term outcome. Breast Cancer Res Treat. 2009;113:307-13 pubmed publisher
    ..All three classifications analyzed were considered inadequate as the prognostic marker of the long-term outcome after NAC and further studies are warranted to optimize the prediction. ..
  20. Hayashi K, Imaizumi T, Uchida K, Kuramochi H, Takasaki K. High response rates in patients with pancreatic cancer using the novel oral fluoropyrimidine S-1. Oncol Rep. 2002;9:1355-61 pubmed
    ..S-1, especially in combination with CDDP, shows promising activity with acceptable toxicities against pancreatic cancer. Further evaluation of this combination in patients with this disease is warranted. ..
  21. Shin M, Ueki K, Kurita H, Kirino T. Malignant transformation of a vestibular schwannoma after gamma knife radiosurgery. Lancet. 2002;360:309-10 pubmed
    ..Our results suggest that radiosurgery induced the malignant transformation, and we propose a cautious application of this treatment for benign tumours. ..
  22. Kobayashi M, Ikeda K, Kawamura Y, Yatsuji H, Hosaka T, Sezaki H, et al. High serum des-gamma-carboxy prothrombin level predicts poor prognosis after radiofrequency ablation of hepatocellular carcinoma. Cancer. 2009;115:571-80 pubmed publisher
    ..020) was a significant prognostic factor for survival. High DCP levels reflect the biologic aggressiveness and progression of HCC tumors. In the aforementioned cases, we recommend surgical resection rather than RFA for such patients. ..
  23. Yamashita H, Nakagawa K, Tago M, Nakamura N, Shiraishi K, Ohtomo K. Salvage radiotherapy for postoperative loco-regional recurrence of esophageal cancer. Dis Esophagus. 2005;18:215-20 pubmed
    ..Additionally, there is symptomatic relief in a substantial proportion of such patients, and long-term survival is possible in some patients. ..
  24. Nakamura M, Ishii K, Watanabe K, Tsuji T, Matsumoto M, Toyama Y, et al. Long-term surgical outcomes for myxopapillary ependymomas of the cauda equina. Spine (Phila Pa 1976). 2009;34:E756-60 pubmed publisher
    ..Therefore, early diagnosis is essential, and a therapeutic strategy including radiotherapy, on the assumption that this tumor is malignant, should be established. ..
  25. Katsumata N, Noda K, Nozawa S, Kitagawa R, Nishimura R, Yamaguchi S, et al. Phase II trial of docetaxel in advanced or metastatic endometrial cancer: a Japanese Cooperative Study. Br J Cancer. 2005;93:999-1004 pubmed
  26. Okegawa T, Kinjo M, Nutahara K, Higashihara E. Pretreatment serum level of HER2/nue as a prognostic factor in metastatic prostate cancer patients about to undergo endocrine therapy. Int J Urol. 2006;13:1197-201 pubmed
    ..The pretreatment serum HER2 level may be a useful independent prognostic factor that is associated with a high risk of biochemical recurrence in metastatic prostate cancer patients about to undergo endocrine therapy. ..
  27. Ohno Y, Izumi M, Yoshioka K, Ohori M, Yonou H, Tachibana M. Prognostic significance of tenascin-C expression in clear cell renal cell carcinoma. Oncol Rep. 2008;20:511-6 pubmed
    ..0345). The tenascin-C expression was strongly related to the stage, nuclear grade and 5-year metastasis-free rate. Therefore, tenascin-C expression may be a possible marker for the metastatic potential of clear cell RCC. ..
  28. Kawai A, Hosono A, Nakayama R, Matsumine A, Matsumoto S, Ueda T, et al. Clear cell sarcoma of tendons and aponeuroses: a study of 75 patients. Cancer. 2007;109:109-16 pubmed
    ..The objective of this study was to determine the clinical features, prognostic factors, and optimal treatment policy for patients with this rare disease...
  29. Abe T, Tanioka D, Sugiyama K, Kawamo M, Murakami K, Izumiyama H. Electromagnetic field system for transsphenoidal surgery on recurrent pituitary lesions - technical note. Surg Neurol. 2007;67:40-4; discussion 44-5 pubmed
    ..It was particularly valuable in the resection of firm tumors. It may also shorten the operating time because of quick vaporization of the firm tissue. ..
  30. Izumi M, Mukai K, Nagai T, Matsubayashi J, Iwaya K, Chiu C, et al. Sebaceous carcinoma of the eyelids: thirty cases from Japan. Pathol Int. 2008;58:483-8 pubmed publisher
  31. Tsuchiya Y, Onda M, Miyashita M, Hagiwara N, Maruyama H, Matsutani T, et al. Combined modality therapy for basaloid squamous carcinoma of the esophagus. Hepatogastroenterology. 1999;46:2868-71 pubmed
    ..Chemotherapy and radiotherapy resulted in the disappearance of the metastasis. The patient has survived for more than 3 years since surgery with a good quality of life...
  32. Kitagawa Y, Ito H, Iketani M, Hirukawa M, Yokoyama M, Maeda S. Epithelioid hemangioendothelioma of the phalanx: a case report. J Hand Surg Am. 2005;30:615-9 pubmed
    ..This was treated by resection of the entire middle phalanx with no recurrence within a 10-year postsurgical follow-up period. We recommend wide resection as the safest treatment for EH of the hand phalanx...
  33. Fujimoto Y, Nakanishi Y, Yoshimura K, Shimoda T. Clinicopathologic study of primary malignant gastrointestinal stromal tumor of the stomach, with special reference to prognostic factors: analysis of results in 140 surgically resected patients. Gastric Cancer. 2003;6:39-48 pubmed
    ..We evaluated the clinicopathological features of a large number of primary malignant gastric GISTs to clarify which features were independent prognostic factors...
  34. Goto H, Kousaka A, Takano S, Usui M. Recurrence of retinoblastoma 12 years after brachytherapy. Am J Ophthalmol. 2002;134:773-5 pubmed
    ..To report a case of retinoblastoma that recurred 12 years after brachytherapy...
  35. Kuroda H, Mochizuki S, Shimoda M, Chijiiwa M, Kamiya K, Izumi Y, et al. ADAM28 is a serological and histochemical marker for non-small-cell lung cancers. Int J Cancer. 2010;127:1844-56 pubmed publisher
    ..05). These data demonstrate that our ELISA is specific and sensitive to monitor the levels of ADAM28 in the samples from NSCLC patients and suggest that ADAM28 is a useful serological and histochemical marker for NSCLC. ..
  36. Kasamatsu T, Hasegawa T, Tsuda H, Okada S, Sawada M, Yamada T, et al. Primary epithelioid sarcoma of the vulva. Int J Gynecol Cancer. 2001;11:316-20 pubmed
    ..Radical vulvectomy or extensive local excision with inguinal lymphadenectomy at the time of diagnosis is recommended as the treatment of choice. ..
  37. Miyazawa J, Mitoro A, Kawashiri S, Chada K, Imai K. Expression of mesenchyme-specific gene HMGA2 in squamous cell carcinomas of the oral cavity. Cancer Res. 2004;64:2024-9 pubmed
    ..01). These results suggest that HMGA2 contributes to the aggressiveness of carcinoma and that detection of HMGA2 expression is a useful predictive and prognostic tool in clinical management of oral carcinomas. ..
  38. Kishino T, Matsuda T, Sakamoto T, Nakajima T, Taniguchi H, Yamamoto S, et al. Recurrent advanced colonic cancer occurring 11 years after initial endoscopic piecemeal resection: a case report. BMC Gastroenterol. 2010;10:87 pubmed publisher
    ..We report a rare case of recurrent advanced colonic cancer diagnosed 11 years after initial EPMR treatment...
  39. Nagane M, Kobayashi K, Ohnishi A, Shimizu S, Shiokawa Y. Prognostic significance of O6-methylguanine-DNA methyltransferase protein expression in patients with recurrent glioblastoma treated with temozolomide. Jpn J Clin Oncol. 2007;37:897-906 pubmed
  40. Itami J, Uno T, Aruga M, Ode S. Local control of piriform sinus cancer treated by radiation therapy alone. Acta Oncol. 1997;36:389-92 pubmed
    ..In addition to the T-stage, other tumor factors should also be considered for predicting local control with radiation therapy...
  41. Takanami I, Imamura T, Naruke M, Kodaira S. Long-term survival after repeated resections of Askin tumor recurrences. Eur J Cardiothorac Surg. 1998;13:313-5 pubmed
    ..It thus may be that postoperative chemo- and radiotherapy after repeated excisions of these local Askin tumor recurrences plays a role in prolonging survival...
  42. Odaka M, Yamazaki S, Akiba T, Mizuno R, Harada T, Yamazaki Y. [A resected case of malignant peripheral nerve sheath tumor (MPNST) necessary to distinguish from Askin tumor]. Jpn J Thorac Cardiovasc Surg. 1998;46:1215-20 pubmed
    ..The diagnosis should be based on the overall findings including the location and clinical data...
  43. Sasaki T, Isayama H, Yashima Y, Yagioka H, Kogure H, Arizumi T, et al. S-1 monotherapy in patients with advanced biliary tract cancer. Oncology. 2009;77:71-4 pubmed publisher
    ..3%), anemia (6.9%), thrombocytopenia (10.3%) and total bilirubin elevation (3.4%). S-1 monotherapy is a feasible and moderately efficacious treatment for advanced biliary tract cancer, as a first- or second-line chemotherapy regimen. ..
  44. Kato H, Usuda J, Okunaka T, Furukawa K, Honda H, Sakaniwa N, et al. Basic and clinical research on photodynamic therapy at Tokyo Medical University Hospital. Lasers Surg Med. 2006;38:371-5 pubmed
    ..Moreover, we introduce basic research on cancers and infectious diseases in order to expand the clinical applications of PDT. ..
  45. Hoya Y, Mitsumori N, Yanaga K. The advantages and disadvantages of a Roux-en-Y reconstruction after a distal gastrectomy for gastric cancer. Surg Today. 2009;39:647-51 pubmed publisher
    ..Roux-en-Y reconstruction or Billroth I operation can only be selected after considering their respective advantages and disadvantages. ..
  46. Ohashi M, Katai H, Fukagawa T, Gotoda T, Sano T, Sasako M. Cancer of the gastric stump following distal gastrectomy for cancer. Br J Surg. 2007;94:92-5 pubmed
    ..The aim of this study was to investigate the clinicopathological features and outcome of CGS following distal gastrectomy for cancer...
  47. Isaka T, Kanzaki M, Kikkawa T, Wachi N, Maeda H, Sakamoto K, et al. [Thoracoscopic subsegmental and segmental resection for postoperative local recurrence of lung cancer based on the three-dimensional structure after lung resection]. Kyobu Geka. 2010;63:973-8 pubmed
    ..For performing radical limited surgery for recurrent lung cancer, avoiding completion pneumonectomy, it is therefore very useful to review the surgical procedures using CTTRY. ..
  48. Wada Hiraike O, Yamamoto N, Osuga Y, Yano T, Kozuma S, Taketani Y. Aberrant implantation and growth of uterine leiomyoma in the abdominal wall after laparoscopically assisted myomectomy. Fertil Steril. 2009;92:1747.e13-5 pubmed publisher
    ..Implantation and growth of uterine leiomyoma fragments after myomectomy is a rare event. However, this complication should be considered as a differential diagnosis when a progressively growing mass is observed at the incision site. ..
  49. Asano K, Miki J, Maeda S, Naruoka T, Takahashi H, Oishi Y. Clinical studies on inverted papilloma of the urinary tract: report of 48 cases and review of the literature. J Urol. 2003;170:1209-12 pubmed
    ..We report on 48 clinicopathologic cases of inverted papilloma and present the clinical significance attributed to these lesions in terms of the current literature...
  50. Ide H, Kikuchi E, Shinoda K, Mukai M, Murai M. Carcinoma in situ developing in an ileal neobladder. Urology. 2007;69:576.e9-11 pubmed
    ..Left nephroureterectomy, resection of the neobladder, and total urethrectomy were performed. The pathologic examination revealed UC (papillary, grade 3) at these anastomoses and carcinoma in situ in the ileal neobladder. ..
  51. Sakura M, Tsukamoto T, Yonese J, Ishikawa Y, Aoki N, Fukui I. Successful therapy of a malignant phyllodes tumor of the prostate after postoperative local failure. Urology. 2006;67:845.e11-3 pubmed
    ..After a good response was achieved with four cycles of the chemotherapy, pelvic irradiation was added. Since then, there has been no evidence of recurrence for more than 4 years...
  52. Matsumoto S, Takeda M, Shibuya H, Suzuki S. T1 and T2 squamous cell carcinomas of the floor of the mouth: results of brachytherapy mainly using 198Au grains. Int J Radiat Oncol Biol Phys. 1996;34:833-41 pubmed
  53. Tominaga T, Adachi I, Sasaki Y, Tabei T, Ikeda T, Takatsuka Y, et al. Double-blind randomised trial comparing the non-steroidal aromatase inhibitors letrozole and fadrozole in postmenopausal women with advanced breast cancer. Ann Oncol. 2003;14:62-70 pubmed
    ..The results show letrozole at a dose of 1.0 mg once daily to be more effective in treating postmenopausal women with advanced breast cancer than fadrozole at 1.0 mg twice daily, with similar safety and tolerability profiles. ..
  54. Kodama H, Iihara M, Nissato S, Isobe K, Kawakami Y, Okamoto T, et al. A large deletion in the succinate dehydrogenase B gene (SDHB) in a Japanese patient with abdominal paraganglioma and concomitant metastasis. Endocr J. 2010;57:351-6 pubmed
    ..Our present findings strongly support the notion that large deletions in the SDHB gene should be considered in patients lacking characterized SDHB mutations...
  55. Itami J, Hara R, Kozuka T, Yamashita H, Nakajima K, Shibata K, et al. Transperineal high-dose-rate interstitial radiation therapy in the management of gynecologic malignancies. Strahlenther Onkol. 2003;179:737-41 pubmed
    ..Clinical experience in high-dose-rate interstitial radiation therapy was retrospectively investigated...
  56. Fukunaga M, Suzuki K, Saegusa N, Folpe A. Composite hemangioendothelioma: report of 5 cases including one with associated Maffucci syndrome. Am J Surg Pathol. 2007;31:1567-72 pubmed
    ..We conclude that composite HE should continue to be regarded as a low-grade malignant vascular tumor (HE), with significant potential for local recurrence, but little if any potential for distant metastasis...
  57. Kawakami S, Kageyama Y, Yonese J, Fukui I, Kitahara S, Arai G, et al. Successful treatment of metastatic adenocarcinoma of the urachus: report of 2 cases with more than 10-year survival. Urology. 2001;58:462 pubmed
    ..These cases provide support for multimodal treatments of metastatic urachal cancer...
  58. Takada T, Amano H, Yasuda H, Nimura Y, Matsushiro T, Kato H, et al. Is postoperative adjuvant chemotherapy useful for gallbladder carcinoma? A phase III multicenter prospective randomized controlled trial in patients with resected pancreaticobiliary carcinoma. Cancer. 2002;95:1685-95 pubmed
  59. Ono M, Ando M, Yunokawa M, Nakano E, Yonemori K, Matsumoto K, et al. Brain metastases in patients who receive trastuzumab-containing chemotherapy for HER2-overexpressing metastatic breast cancer. Int J Clin Oncol. 2009;14:48-52 pubmed publisher
    ..3%). Routine screening for brain metastases 1 year after the start of trastuzumab treatment, may be warranted in younger patients (</=50 years) who had recurrent breast cancer with liver metastases. ..
  60. Yamaguchi S, Nagasawa H, Suzuki T, Fujii E, Iwaki H, Takagi M, et al. Sarcomas of the oral and maxillofacial region: a review of 32 cases in 25 years. Clin Oral Investig. 2004;8:52-5 pubmed
    ..Adequate excision with safety surgical margin as the initial therapy is important for better survival. The value of radiation therapy and/or chemotherapy is uncertain. The 5-year survival rate of primary cases was 61%...
  61. Satoh Y, Hoshi R, Ishikawa Y, Horai T, Okumura S, Nakagawa K. Recurrence patterns in patients with early stage non-small cell lung cancers undergoing positive pleural lavage cytology. Ann Thorac Surg. 2007;83:197-202 pubmed
    ..Moreover, curative resection, followed by adjuvant systemic therapy, could be necessary for improvement of outcome. ..
  62. Yomo S, Hayashi M, Chernov M, Tamura N, Izawa M, Okada Y, et al. Stereotactic radiosurgery of residual or recurrent craniopharyngioma: new treatment concept using Leksell gamma knife model C with automatic positioning system. Stereotact Funct Neurosurg. 2009;87:360-7 pubmed publisher
    ..The present study analyzed the initial experience with the application of the original concept of 'robotic microradiosurgery' using Leksell Gamma Knife Model C with automatic positioning system for management of craniopharyngiomas...
  63. Jimbo H, Kamata S, Miura K, Asamoto S, Tada S, Endo T, et al. Operative management of skull base malignant tumors arising from the nasal cavity and paranasal sinus: recent strategies used in 25 cases. Neurol Med Chir (Tokyo). 2010;50:20-6; discussion 26 pubmed
    ..We believe that the optimal management of such malignant tumors involves a multimodal and multidisciplinary team approach. Here we present our recent institutional experience and treatment policy employed during the past 3 years...
  64. Azuhata T, Scott D, Griffith T, Miller M, Sandler A. Survivin inhibits apoptosis induced by TRAIL, and the ratio between survivin and TRAIL receptors is predictive of recurrent disease in neuroblastoma. J Pediatr Surg. 2006;41:1431-40 pubmed
    ..The cell's sensitivity to TRAIL is at least partially governed by both TRAIL-R and survivin expression, whereas the ratio between these 2 factors appears to have prognostic value in patients with this disease. ..
  65. Sato H, Uzawa N, Takahashi K, Myo K, Ohyama Y, Amagasa T. Prognostic utility of chromosomal instability detected by fluorescence in situ hybridization in fine-needle aspirates from oral squamous cell carcinomas. BMC Cancer. 2010;10:182 pubmed publisher
    ..035) and overall survival (p = .041). Analysis of CIN status using FISH on FNA biopsy specimens may be useful in predicting of recurrence and poor prognosis in patients with oral SCCs. ..
  66. Kobayashi K, Nakao K, Yoshida M, Ando M, Ebihara Y, Asakage T, et al. Recurrent cancer of the parotid gland: how well does salvage surgery work for locoregional failure?. ORL J Otorhinolaryngol Relat Spec. 2009;71:239-43 pubmed publisher
    ..Many articles have discussed the clinical features of previously untreated parotid cancer, but the clinical characteristics and treatment of recurrent parotid cancer have not yet been fully described...
  67. Yoshida H, Mamada Y, Taniai N, Kawano Y, Mizuguchi Y, Shimizu T, et al. Percutaneous transhepatic insertion of metal stents with a double-pigtail catheter in afferent loop obstruction following distal gastrectomy. Hepatogastroenterology. 2005;52:680-2 pubmed
    ..A double-pigtail catheter was inserted into the metal stents to prevent migration. Good stent placement was confirmed and the drainage catheter was removed. ..
  68. Uemura N, Nakanishi Y, Kato H, Saito S, Nagino M, Hirohashi S, et al. Transglutaminase 3 as a prognostic biomarker in esophageal cancer revealed by proteomics. Int J Cancer. 2009;124:2106-15 pubmed publisher
    ..These results establish TGM3 as a novel prognostic biomarker for ESCC for the first time. Examination of TGM3 expression may provide novel therapeutic strategies to prevent recurrence of ESCC. ..
  69. Kurokawa R, Uchida K, Kawase T. Surgical treatment of temporal bone chondroblastoma. Surg Neurol. 2005;63:265-8; discussion 268 pubmed
    ..However, the literature provides little information regarding long-term results after wide resection of temporal bone chondroblastoma...
  70. Kawachi R, Tsukada H, Nakazato Y, Takei H, Furuyashiki G, Koshi ishi Y, et al. Early recurrence after surgical resection in patients with pathological stage I non-small cell lung cancer. Thorac Cardiovasc Surg. 2009;57:472-5 pubmed publisher
    ..In patients with these factors, adjuvant therapy may be indicated since this may improve their survival. ..
  71. Hiroishi K, Eguchi J, Baba T, Shimazaki T, Ishii S, Hiraide A, et al. Strong CD8(+) T-cell responses against tumor-associated antigens prolong the recurrence-free interval after tumor treatment in patients with hepatocellular carcinoma. J Gastroenterol. 2010;45:451-8 pubmed publisher
    ..Immunotherapy to induce TAA-specific cytotoxic T lymphocytes by means such as the use of peptide vaccines should be considered for clinical application in patients with HCC after local therapy. ..
  72. Yoshimura R, Kagami Y, Ito Y, Asai M, Mayahara H, Sumi M, et al. Outcomes in patients with early-stage hypopharyngeal cancer treated with radiotherapy. Int J Radiat Oncol Biol Phys. 2010;77:1017-23 pubmed publisher
    ..To analyze the outcome in patients with early-stage hypopharyngeal cancer (HPC) who were treated with radiotherapy (RT)...
  73. Wang Y, Takanashi M, Tsuji K, Tanaka N, Shiseki M, Mori N, et al. Level of DNA topoisomerase IIalpha mRNA predicts the treatment response of relapsed acute leukemic patients. Leuk Res. 2009;33:902-7 pubmed publisher
    ..These results suggest that the change of Topo IIalpha expression in leukemic blasts at relapse may predict therapeutic responsiveness. ..
  74. Fujita I, Kiyama T, Chou K, Kanno H, Naito Z, Uchida E. A case of metastatic hemangiopericytoma occurring 16 years after initial presentation: with special reference to the clinical behavior and treatment of metastatic hemangiopericytoma. J Nippon Med Sch. 2009;76:221-5 pubmed
    ..Careful long-term follow-up is required because metastases can develop after an extended disease-free interval. Aggressive surgical treatment is recommended for distant metastases...
  75. Yonemori K, Tsuta K, Shimizu C, Hatanaka Y, Hashizume K, Ono M, et al. Immunohistochemical expression of PTEN and phosphorylated Akt are not correlated with clinical outcome in breast cancer patients treated with trastuzumab-containing neo-adjuvant chemotherapy. Med Oncol. 2009;26:344-9 pubmed publisher
    ..Except among patients with pathological complete remission, the persistent over-expression of HER2/neu may be a poor prognostic factor. ..
  76. Yamada D, Kikuchi S, Williams Y, Sakurai Yageta M, Masuda M, Maruyama T, et al. Promoter hypermethylation of the potential tumor suppressor DAL-1/4.1B gene in renal clear cell carcinoma. Int J Cancer. 2006;118:916-23 pubmed
    ..038, relative risk 10.5). These results indicate that the promoter methylation of the 4.1B is one of the most frequent epigenetic alterations in RCCC and could predict the metastatic recurrence of the surgically resected RCCC. ..
  77. Osako T, Ito Y, Morimatsu A, Tada K, Sakurai N, Takahashi S, et al. Flare-up of dermatomyositis along with recurrence of breast cancer. Breast J. 2007;13:200-2 pubmed
  78. Matsubayashi S, Yoshihara T. Carcinoma ex pleomorphic adenoma of the salivary gland: an immunohistochemical study. Eur Arch Otorhinolaryngol. 2007;264:789-95 pubmed
    ..These results suggest that Ca-ex-PA acquired the particular biological behavior in contrast to the other salivary neoplasms in the long-standing process while PA undergoes malignant transformation...
  79. Iimura J, Otori N, Hatano A, Moriyama H. [Importance of tumor origin determination in selecting suitable surgery for treating inverted maxillary sinus papillomas]. Nihon Jibiinkoka Gakkai Kaiho. 2009;112:783-90 pubmed
    ..The tool essential for successful tumor removal is complete surgical resection so as our study demonstrates, the preoperative determination of tumor origin is important in selecting of the most appropriate surgical procedure...
  80. Ono M, Watanabe T, Shimizu C, Hiramoto N, Goto Y, Yonemori K, et al. Therapy-related acute promyelocytic leukemia caused by hormonal therapy and radiation in a patient with recurrent breast cancer. Jpn J Clin Oncol. 2008;38:567-70 pubmed publisher
    ..This patient is thought to be a rare case of secondary leukemia, since the leukemia might have been caused by hormonal therapy and regional radiation without chemotherapy...
  81. Watanabe T, Katayama Y, Yoshino A, Yachi K, Ohta T, Ogino A, et al. Aberrant hypermethylation of p14ARF and O6-methylguanine-DNA methyltransferase genes in astrocytoma progression. Brain Pathol. 2007;17:5-10 pubmed
    ..Our findings suggest that p14(ARF) hypermethylation and MGMT hypermethylation constitute distinct molecular pathways of astrocytoma progression, which could differ in biological behavior and clinical outcome. ..
  82. Yamashita H, Kobayashi Shibata S, Terahara A, Okuma K, Haga A, Wakui R, et al. Prescreening based on the presence of CT-scan abnormalities and biomarkers (KL-6 and SP-D) may reduce severe radiation pneumonitis after stereotactic radiotherapy. Radiat Oncol. 2010;5:32 pubmed publisher
    ..Therefore, pre-screening before SBRT for an IP shadow in CT and serum KL-6 & SP-D is recommended in the management and treatment of patients with primary or secondary lung tumors. ..
  83. Tanaka M, Tabata M, Shimokawa T, Takanashi S. The rupture of descending thoracic aorta due to the necrosis of aortic intimal sarcoma. Interact Cardiovasc Thorac Surg. 2010;10:462-3 pubmed publisher
    ..The patient developed a local recurrence and abdominal dissemination of the tumor three months after surgery. We report the case and discuss about the diagnosis and treatment of thoracic aortic intimal sarcoma...
  84. Yasen M, Mizushima H, Mogushi K, Obulhasim G, Miyaguchi K, Inoue K, et al. Expression of Aurora B and alternative variant forms in hepatocellular carcinoma and adjacent tissue. Cancer Sci. 2009;100:472-80 pubmed publisher
    ..This is the first study to report clinicopathological significance of aberrant expression of AURKB-Sv2 variant form in hepatocellular carcinoma. ..
  85. Nakata M, Miwa Y, Nakayama H, Sakai T, Sasaki N. Localised radiotherapy for a ferret with possible anal sac apocrine adenocarcinoma. J Small Anim Pract. 2008;49:476-8 pubmed publisher
    ..Cytology of a sample of the pleural effusion suggested mesothelioma, and no obvious pulmonary metastasis of anal sac adenocarcinoma were identified on thoracic radiography. The ferret died at home on day 71 after the first admission...
  86. Orimo T, Ojima H, Hiraoka N, Saito S, Kosuge T, Kakisaka T, et al. Proteomic profiling reveals the prognostic value of adenomatous polyposis coli-end-binding protein 1 in hepatocellular carcinoma. Hepatology. 2008;48:1851-63 pubmed publisher
    ..256; 95% confidence interval, 1.337-3.807; P = 0.002) of patients with HCC after curative surgery. Proteomic profiling revealed the molecular signature behind the progression of HCC, and the prognostic value of EB1 in HCC. ..
  87. Saito K, Tatokoro M, Fujii Y, Iimura Y, Koga F, Kawakami S, et al. Impact of C-reactive protein kinetics on survival of patients with metastatic renal cell carcinoma. Eur Urol. 2009;55:1145-53 pubmed publisher
    ..CRP can be a novel, widely available biomarker for patients with mRCC. ..
  88. Tanimura S, Saito Y, Honma K, Koizumi K. Surgical case of giant malignant mesenchymoma in the posterior mediastinum that recurred in the bilateral mediastinum. J Nippon Med Sch. 2008;75:212-5 pubmed
    ..The patient had local recurrence in both sides of the mediastinum 3 years and 6 months after surgery, and the recurrent tumors were completely resected again...