Experts and Doctors on humans in Aichi, Japan


Locale: Aichi, Japan
Topic: humans

Top Publications

  1. Horibe Y, Murakami M, Yamao K, Imaeda Y, Tashiro K, Kasahara M. Epithelial inclusion cyst (epidermoid cyst) formation with epithelioid cell granuloma in an intrapancreatic accessory spleen. Pathol Int. 2001;51:50-4 pubmed
    ..Frequent recurrence of chronic inflammation and epitheloid cell granuloma formation may have resulted from an aberration of the ectopic remaining pancreatic tissue in the spleen. ..
  2. Hayashi Y, Kim K, Fujiwara H, Shimono C, Yamashita M, Sanzen N, et al. Identification and recombinant production of human laminin alpha4 subunit splice variants. Biochem Biophys Res Commun. 2002;299:498-504 pubmed
    ..Since both alpha4A and alpha4B transcripts were detected by RT-PCR in several human cell lines, these two isoforms of laminin-8 with differing cell-adhesive activities are present in the basement membranes of human tissues. ..
  3. Yoshikawa Y, Ono Y, Hattori R, Gotoh M, Yoshino Y, Katsuno S, et al. Laparoscopic partial nephrectomy for renal tumor: Nagoya experience. Urology. 2004;64:259-63 pubmed
    ..A vascular clamp was indicated for patients with less-than-1-cm-thick renal parenchyma between the tumor mass and renal sinus or calices. ..
  4. Nagashima C, Tomitaka Yagami A, Tsuruta K, Yatsushiro H, Akamatsu H, Matsunaga K, et al. Electron-beam treatment of allergic granuloma due to gold pierced earrings. Contact Dermatitis. 2004;51:90-1 pubmed
  5. Chang H, Joko M, Song J, Ito K, Inoue T, Nakagawa H. Ultrasonic bone curettage for optic canal unroofing and anterior clinoidectomy. Technical note. J Neurosurg. 2006;104:621-4 pubmed
    ..The ultrasonic bone curette makes the unroofing of the optic canal safer and easier, possibly improving the visual outcome of patients undergoing surgery for parasellar tumors. ..
  6. Ishida T, Ishii T, Inagaki A, Yano H, Komatsu H, Iida S, et al. Specific recruitment of CC chemokine receptor 4-positive regulatory T cells in Hodgkin lymphoma fosters immune privilege. Cancer Res. 2006;66:5716-22 pubmed
  7. Okochi T, Ikeda M, Kishi T, Kawashima K, Kinoshita Y, Kitajima T, et al. Meta-analysis of association between genetic variants in COMT and schizophrenia: an update. Schizophr Res. 2009;110:140-8 pubmed publisher
    ..This significance did not remain, however, after correcting the P-values using a false discovery rate controlling procedure. Our results suggest that the COMT is unlikely to contribute to susceptibility to schizophrenia. ..
  8. Kitamura Y, Kurosawa G, Tanaka M, Sumitomo M, Muramatsu C, Eguchi K, et al. Frequent overexpression of CADM1/IGSF4 in lung adenocarcinoma. Biochem Biophys Res Commun. 2009;383:480-4 pubmed publisher
    ..Moreover, some clones among the eight mAbs gave different staining patterns from those by the other clones against the same fresh specimen, suggesting presence of variant forms of CADM1 differentiated by mAbs. ..
  9. Ogawa H, Shionyu M, Sugiura N, Hatano S, Nagai N, Kubota Y, et al. Chondroitin sulfate synthase-2/chondroitin polymerizing factor has two variants with distinct function. J Biol Chem. 2010;285:34155-67 pubmed publisher
    ..Molecular modeling of CSS2A and CSS2B provided support for their properties. These findings, implicating regulation of CS chain polymerization by CSS2 variants, provide insight in elucidating the mechanisms of CS biosynthesis...

More Information

Publications439 found, 100 shown here

  1. Kakizaki H, Valenzuela A. Lacrimal caruncle: continuation to the lower eyelid retractors. Ophthalmic Plast Reconstr Surg. 2011;27:198-200 pubmed publisher
  2. Sugiura T, Kouwaki M, Togawa Y, Sugimoto M, Togawa T, Koyama N. Neurodevelopmental outcomes at 18 months' corrected age of infants born at 22 weeks of gestation. Neonatology. 2011;100:228-32 pubmed publisher
    ..This might suggest that infants after 22 weeks' gestation be considered eligible for active treatment in Japan, though considering the size of the material, generalizibility of the results cannot be considered guaranteed. ..
  3. Kokubo Y, Yokoyama Y, Kisara K, Ohira Y, Sunami A, Yoshizaki T, et al. Relationship Between Dietary Factors and Bodily Iron Status Among Japanese Collegiate Elite Female Rhythmic Gymnasts. Int J Sport Nutr Exerc Metab. 2016;26:105-13 pubmed publisher
    ..669, 0.990], p = .039). Participants in the preseason's weight-loss periods showed a tendency toward insufficient nutrient intake and were at a high risk for ID, particularly because of lower protein intake. ..
  4. Tsushima Y, Ishiguchi T, Murakami T, Hayashi H, Hayakawa K, Fukuda K, et al. Safe use of iodinated and gadolinium-based contrast media in current practice in Japan: a questionnaire survey. Jpn J Radiol. 2016;34:130-9 pubmed publisher
    ..Our questionnaire survey revealed that preventive actions against CIN were properly performed based on patients' eGFR. Preventive actions against NSF and AAR still lacked consensus. ..
  5. Usui H, Nishida Y. The very low-frequency band of heart rate variability represents the slow recovery component after a mental stress task. PLoS ONE. 2017;12:e0182611 pubmed publisher
    ..This VLF characteristic may clarify the unexplained association of the VLF band in cardiovascular disease prevention. ..
  6. Ota A, Ichinose H, Nagatsu T. Mouse sepiapterin reductase: an enzyme involved in the final step of tetrahydrobiopterin biosynthesis. Primary structure deduced from the cDNA sequence. Biochim Biophys Acta. 1995;1260:320-2 pubmed
    ..The amino acid sequence of mouse sepiapterin reductase revealed the identity of 88% with rat and 74% with human sequence. ..
  7. Kumagai K, Nishiwaki K, Sato K, Kitamura H, Yano K, Komatsu T, et al. [Perioperative management of a patient with purpura fulminans syndrome due to protein C deficiency]. Can J Anaesth. 2001;48:1070-4 pubmed
    ..Replacement therapy with activated protein C concentrate appears safe and effective. The anesthetic management is reviewed and discussed. ..
  8. Senga T, Iwamoto S, Yoshida T, Yokota T, Adachi K, Azuma E, et al. LSSIG is a novel murine leukocyte-specific GPCR that is induced by the activation of STAT3. Blood. 2003;101:1185-7 pubmed
    ..These results suggest that LSSIG and GPR43 might play pivotal roles in differentiation and immune response of monocytes and granulocytes. ..
  9. Kinoshita Y, Suzuki T, Ikeda M, Kitajima T, Yamanouchi Y, Inada T, et al. No association with the calcineurin A gamma subunit gene (PPP3CC) haplotype to Japanese schizophrenia. J Neural Transm (Vienna). 2005;112:1255-62 pubmed
    ..To our regret, we could not confirm the association with Japanese schizophrenia to PPP3CC including core at-risk haplotype. Our result suggests that PPP3CC may not play a major role in Japanese schizophrenia. ..
  10. Sato T, Takahashi S, Mizumoto T, Harao M, Akizuki M, Takasugi M, et al. Neutrophil elastase and cancer. Surg Oncol. 2006;15:217-22 pubmed
    ..The use of NE inhibitor would seem to be a promising way to prevent the invasion and metastasis of cancer. ..
  11. Anil S, Kato Y, Hayakawa M, Yoshida K, Nagahisha S, Kanno T. Virtual 3-dimensional preoperative planning with the dextroscope for excision of a 4th ventricular ependymoma. Minim Invasive Neurosurg. 2007;50:65-70 pubmed
    ..Integration of 3-dimensional imaging with stereoscopic vision makes understanding the complex anatomy easier and helps improve decision making in patient management. ..
  12. Mori A, Ohashi N, Maruyama T, Tatebe H, Sakai K, Shibuya T, et al. Transnasal endoscopic retrograde chalangiopancreatography using an ultrathin endoscope: a prospective comparison with a routine oral procedure. World J Gastroenterol. 2008;14:1514-20 pubmed
  13. Ikeda M, Yamanouchi Y, Kinoshita Y, Kitajima T, Yoshimura R, Hashimoto S, et al. Variants of dopamine and serotonin candidate genes as predictors of response to risperidone treatment in first-episode schizophrenia. Pharmacogenomics. 2008;9:1437-43 pubmed publisher
    ..These data suggest that the SNPs in DRD2 and AKT1 may influence the treatment response to risperidone in schizophrenia patients. ..
  14. Takeuchi T, Inomata K. Visual search strategies and decision making in baseball batting. Percept Mot Skills. 2009;108:971-80 pubmed
    ..Expert baseball batters used visual search strategies to gaze at specific cues (the pitching arm of the pitcher) and were more accurate and relatively quicker at decision making than Nonexpert batters. ..
  15. Holder G, Celesia G, Miyake Y, Tobimatsu S, Weleber R. International Federation of Clinical Neurophysiology: recommendations for visual system testing. Clin Neurophysiol. 2010;121:1393-1409 pubmed publisher
    ..This document presents recommendations and guidelines for the use of visual electrophysiological testing in the clinical assessment of visual pathway function. ..
  16. Kakizaki H, Takahashi Y, Asamoto K, Nakano T, Selva D, Leibovitch I. Anatomy of the superior border of the lateral orbital wall: surgical implications in deep lateral orbital wall decompression surgery. Ophthalmic Plast Reconstr Surg. 2011;27:60-3 pubmed publisher
    ..To avoid dural exposure, the cortical bone should not be exposed at the junction between the superior and posterior borders of the lateral orbital wall, which corresponds to the junction of the anterior and middle cranial fossae. ..
  17. Ichino N, Osakabe K, Nishikawa T, Sugiyama H, Kato M, Kitahara S, et al. A new index for non-invasive assessment of liver fibrosis. World J Gastroenterol. 2010;16:4809-16 pubmed
    ..The Fibro-Stiffness index was constructed and validated. It showed superior diagnostic performance to other indices for F ? 2, 3 and 4. ..
  18. Suzuki Y, Nakayama K, Hashimoto N, Yazawa I. Proteolytic processing regulates pathological accumulation in dentatorubral-pallidoluysian atrophy. FEBS J. 2010;277:4873-87 pubmed publisher
    ..Collectively, these results suggest that the C-terminal fragment plays a principal role in the pathological accumulation of ATN1 in dentatorubral-pallidoluysian atrophy. ..
  19. Nagatomo K, Ishii H, Yamamoto T, Nakajo K, Kubo Y. The Met268Pro mutation of mouse TRPA1 changes the effect of caffeine from activation to suppression. Biophys J. 2010;99:3609-18 pubmed publisher
  20. Tahara T, Shibata T, Nakamura M, Yamashita H, Yoshioka D, Okubo M, et al. Effect of IL-1? and TNF-? polymorphisms on the prognosis and survival of gastric cancer patients. Clin Exp Med. 2011;11:211-7 pubmed publisher
    ..IL-1?-31CC, IL-1?-511TT genotype, and TNF-?-857T carrier may have protective effect against GC progression. ..
  21. Muramatsu H, Takahashi Y, Shimoyama Y, Doisaki S, Nishio N, Ito Y, et al. CD20-negative Epstein-Barr virus-associated post-transplant lymphoproliferative disease refractory to rituximab in a patient with severe aplastic anemia. Int J Hematol. 2011;93:779-781 pubmed publisher
    ..Similar to other types of lymphoma, the absence of CD20 antigen is likely to be characteristic of rituximab-refractory EBV-PTLD. ..
  22. Sasaki M, Ogasawara N, Funaki Y, Mizuno M, Iida A, Goto C, et al. Transglucosidase improves the gut microbiota profile of type 2 diabetes mellitus patients: a randomized double-blind, placebo-controlled study. BMC Gastroenterol. 2013;13:81 pubmed publisher
    ..umin-ctr umin000010318. ..
  23. Kitagawa Y, Takeuchi H, Takagi Y, Natsugoe S, Terashima M, Murakami N, et al. Sentinel node mapping for gastric cancer: a prospective multicenter trial in Japan. J Clin Oncol. 2013;31:3704-10 pubmed publisher
    ..The endoscopic dual tracer method for SN biopsy was confirmed as safe and effective when applied to the superficial, relatively small gastric adenocarcinomas included in this study. ..
  24. Nagashima M, Yamagishi Y, Mikamo H. Antifungal susceptibilities of Candida species isolated from the patients with vaginal candidiasis. J Infect Chemother. 2016;22:124-6 pubmed publisher
    ..albicans and C. glabrata isolates from vaginitis. CTZ, OCZ and ICZ susceptibility of FLCZ low susceptibility C. glabrata are relatively higher than MCZ, ITCZ and FLCZ. ..
  25. Oga T, Taniguchi H, Kita H, Tsuboi T, Tomii K, Ando M, et al. Validation of the Japanese Severe Respiratory Insufficiency Questionnaire in hypercapnic patients with noninvasive ventilation. Respir Investig. 2017;55:166-172 pubmed publisher
    ..It has high psychometric properties with internal consistency and concurrent validity. The Japanese SRI Questionnaire can be used to assess HRQL in patients on NIV for CHRF. ..
  26. Tsukamura M, Ichiyama S, Miyachi T. Superiority of enviomycin or streptomycin over ethambutol in initial treatment of lung disease caused by Mycobacterium avium complex. Chest. 1989;95:1056-8 pubmed
    ..No statistically significant difference was observed between the regimens rifampin + isoniazid + enviomycin and rifampin + isoniazid + streptomycin. ..
  27. Okumura A, Hayakawa F, Kato T, Maruyama K, Kubota T, Suzuki M, et al. Abnormal sharp transients on electroencephalograms in preterm infants with periventricular leukomalacia. J Pediatr. 2003;143:26-30 pubmed
    ..The presence of two or more types of abnormal sharp transients was correlated with a poor outcome. FS or OS may be useful for predicting which infant will have PVL. ..
  28. Hayashi N, Nakagawa C, Ito Y, Takasaki A, Jinbo Y, Yamakawa Y, et al. Myristoylation-regulated direct interaction between calcium-bound calmodulin and N-terminal region of pp60v-src. J Mol Biol. 2004;338:169-80 pubmed
    ..These results demonstrate clearly the direct interaction between pp60v-src and Ca2+/CaM in a novel manner different from that of known Ca2+/CaM, the target molecules, interactions. ..
  29. Tagawa H, Tsuzuki S, Suzuki R, Karnan S, Ota A, Kameoka Y, et al. Genome-wide array-based comparative genomic hybridization of diffuse large B-cell lymphoma: comparison between CD5-positive and CD5-negative cases. Cancer Res. 2004;64:5948-55 pubmed
    ..These results suggest that array-based comparative genomic hybridization analysis provides a platform of genomic aberrations of DLBCL both common and specific to clinically distinct subgroups. ..
  30. Matsui T, Kojima H, Suzuki H, Hamajima H, Nakazato H, Ito K, et al. Sialyl Lewisa expression as a predictor of the prognosis of colon carcinoma patients in a prospective randomized clinical trial. Jpn J Clin Oncol. 2004;34:588-93 pubmed
    ..This prospective study in a randomized controlled trial suggests that sialyl Lewis(a) expression levels may serve as an indicator of the metastatic potential of colon cancer cells, which would strongly predict the prognosis. ..
  31. Ihira M, Akimoto S, Miyake F, Fujita A, Sugata K, Suga S, et al. Direct detection of human herpesvirus 6 DNA in serum by the loop-mediated isothermal amplification method. J Clin Virol. 2007;39:22-6 pubmed
    ..The loop-mediated isothermal amplification method (LAMP) can detect viral DNA with high specificity, efficiency, and speed under isothermal conditions. LAMP requires only simple equipment that is available in hospital laboratories...
  32. Nakashima A, Hayashi N, Kaneko Y, Mori K, Sabban E, Nagatsu T, et al. RNAi of 14-3-3eta protein increases intracellular stability of tyrosine hydroxylase. Biochem Biophys Res Commun. 2007;363:817-21 pubmed
    ..The stability of the mutant with the N-terminus deleted up to Glu(43) was not affected by the down-regulation of 14-3-3eta. These results suggest that the 14-3-3eta protein regulates hTH1 stability by acting on the N-terminus. ..
  33. Kishida T, Yabushita H, Wakatsuki A, Zhuo L, Kimata K. Hyaluronan (HA) and serum-derived hyaluronan-associated protein (SHAP)-HA complex as predictive markers of cervical ripening in premature labor. Connect Tissue Res. 2008;49:105-8 pubmed publisher
    ..Increased levels of SHAP-HA complex in sera are possible predictive markers for cervical ripening in premature labor. ..
  34. Kakizaki H, Chan W, Madge S, Malhotra R, Selva D. Lower eyelid retractors in Caucasians. Ophthalmology. 2009;116:1402-4 pubmed publisher
    ..The lower eyelid retractors in Caucasians consist of clear double layers. In this regard, no differences were detected between Caucasian and Asian eyelid anatomic features. ..
  35. Kakizaki H, Maden A, Türe M, Yilmaz S, Chan W. Hemangiopericytoma-solitary fibrous tumor of the eyelid. Ophthalmic Plast Reconstr Surg. 2010;26:46-8 pubmed publisher
    ..Although initial tumor removal was complete, the patient required a subsequent operation for his residual ectropion. Despite the lesion being large at presentation, surgical intervention resulted in good functional and cosmetic outcome. ..
  36. Naniwa T, Maeda T, Shimizu S, Ito R. Hepatitis B virus-related polyarteritis nodosa presenting with multiple lung nodules and cavitary lesions. Chest. 2010;138:195-7 pubmed publisher
  37. Ito S, Wakamatsu K. Human hair melanins: what we have learned and have not learned from mouse coat color pigmentation. Pigment Cell Melanoma Res. 2011;24:63-74 pubmed publisher
    ..Based on these data, a hypothesis is proposed to explain the diversity of human hair pigmentation. ..
  38. Kishi T, Fukuo Y, Kitajima T, Okochi T, Yamanouchi Y, Kinoshita Y, et al. SIRT1 gene, schizophrenia and bipolar disorder in the Japanese population: an association study. Genes Brain Behav. 2011;10:257-63 pubmed publisher
    ..89 × 10(-15)). Also, four tagging SNPs in the SIRT1 gene were not associated with BP. In conclusion, the SIRT1 gene may play an important role in the pathophysiology of schizophrenia in the Japanese population. ..
  39. Ishida Y, Honda M, Kamibeppu K, Ozono S, Okamura J, Asami K, et al. Social outcomes and quality of life of childhood cancer survivors in Japan: a cross-sectional study on marriage, education, employment and health-related QOL (SF-36). Int J Hematol. 2011;93:633-644 pubmed publisher
    ..006). The CCSs had made efforts to attain educational/vocational goals; however, a significant proportion of CCSs who had experienced late effects remain at increased risk of experiencing diminished QOL. ..
  40. Nakagawa Y, Nakamura S, Nakajima M, Endo H, Dohda T, Takayama N, et al. Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell-derived megakaryocytes. Exp Hematol. 2013;41:742-8 pubmed publisher
    ..e., iPSC-derived MKs) in numbers sufficient for transfusion therapy. ..
  41. Ota S, Miyamura H, Nishizawa H, Inagaki H, Inagaki A, Inuzuka H, et al. Contribution of fetal ANXA5 gene promoter polymorphisms to the onset of pre-eclampsia. Placenta. 2013;34:1202-10 pubmed publisher
  42. Hira D, Komase Y, Koshiyama S, Oguma T, Hiramatsu T, Shiraki A, et al. Problems of elderly patients on inhalation therapy: Difference in problem recognition between patients and medical professionals. Allergol Int. 2016;65:444-449 pubmed publisher
  43. Iwashita Y, Hibi T, Ohyama T, Honda G, Yoshida M, Miura F, et al. An opportunity in difficulty: Japan-Korea-Taiwan expert Delphi consensus on surgical difficulty during laparoscopic cholecystectomy. J Hepatobiliary Pancreat Sci. 2017;24:191-198 pubmed publisher
    ..The median point for each item was set as the difficulty score. A Delphi consensus was reached among expert LC surgeons on the impact of intraoperative findings on surgical difficulty. ..
  44. Fujita K, Shibayama K, Yamauchi M, Kato T, Ando M, Takahashi H, et al. Alteration of enzymatic activities implicating neuronal degeneration in the spinal cord of the motor neuron degeneration mouse during postnatal development. Neurochem Res. 1998;23:557-62 pubmed
    ..These biochemical alterations became evident prior to the appearance of clinical motor dysfunction which were observed in later stages of development in Mnd spinal cord. ..
  45. Odori T, Goto H, Arisawa T, Niwa Y, Ohmiya N, Hayakawa T. Clinical results and development of variable-stiffness video colonoscopes. Endoscopy. 2001;33:65-9 pubmed
    ..These results suggest that only one scope, the XCF-Q240A1, is needed for any colonic examination by any examiner. ..
  46. Shimada Y, Horiguchi M. Stray light-induced multifocal electroretinograms. Invest Ophthalmol Vis Sci. 2003;44:1245-51 pubmed
    ..Thus, care must be taken when focal lesions are investigated with mfERGs. ..
  47. Yabushita H, Noguchi M, Obayashi Y, Kishida T, Noguchi Y, Sawaguchi K, et al. Angiostatin expression in ovarian cancer. Oncol Rep. 2003;10:1225-30 pubmed
    ..The presence of angiostatin expression and absence of VEGF expression are favorable prognostic factors with regard to survival in ovarian carcinoma patients. ..
  48. Matsumoto K, Shionyu M, Go M, Shimizu K, Shinomura T, Kimata K, et al. Distinct interaction of versican/PG-M with hyaluronan and link protein. J Biol Chem. 2003;278:41205-12 pubmed
    ..These results provide important insights into the mechanisms of formation of the proteoglycan aggregate and HA binding of molecules containing the link module. ..
  49. Matsubara M, Titani K, Taniguchi H, Hayashi N. Direct involvement of protein myristoylation in myristoylated alanine-rich C kinase substrate (MARCKS)-calmodulin interaction. J Biol Chem. 2003;278:48898-902 pubmed
    ..A mutation study suggested that the importance of the positive charge in the N-terminal protein domain in the binding. ..
  50. Kamoshida S, Shiogama K, Shimomura R, Inada K, Sakurai Y, Ochiai M, et al. Immunohistochemical demonstration of fluoropyrimidine-metabolizing enzymes in various types of cancer. Oncol Rep. 2005;14:1223-30 pubmed
    ..Fluoropyrimidine treatment may be selected, based on the simultaneous immunohistochemical evaluation of the fluoropyrimidine metabolic enzymes. ..
  51. Taniguchi K, Wakuda M. [Picobirnavirus]. Uirusu. 2005;55:297-302 pubmed
    ..Recently, complete nucleotide sequences of two RNA segments of a human picobirnavirus detected in Thailand were determined. ..
  52. Zhuo L, Kanamori A, Kannagi R, Itano N, Wu J, Hamaguchi M, et al. SHAP potentiates the CD44-mediated leukocyte adhesion to the hyaluronan substratum. J Biol Chem. 2006;281:20303-14 pubmed
    ..Leukocytes infiltrated to the synovium were strongly positive for HA, SHAP, and CD44 on their surfaces, suggesting a role for the adhesion-enhancing effect of SHAP in pathogenesis. ..
  53. Inoue T. [Difference in transmissibility between bronchial and laryngeal tuberculosis--a retrospective epidemiological study of TB patients newly registered in recent 19 years in Aichi Prefecture, Japan]. Kekkaku. 2006;81:419-24 pubmed
    ..1% and 20.0% (p< 0.05), respectively, in smear-positive patients, and 0% and 20.0% (p=0.18, not significant) in those patients with no chest pathology. These findings suggest that bronchial TB is less infectious than laryngeal TB. ..
  54. Ihira M, Ohta A, Sugata K, Suga S, Asano Y, Yoshikawa T. Loop-mediated isothermal amplification for discriminating between human herpesvirus 6 A and B. J Virol Methods. 2008;154:223-5 pubmed publisher
    ..HHV-6 DNA was amplified directly from the serum samples and all 20 LAMP products were positive for HHV-6 B...
  55. Kurokawa K, Mouri Y, Asano A, Kamei K, Iwata Y, Isogai M, et al. Pleomorphic carcinoma with osteoclastic giant cells of the breast: immunohistochemical differentiation between coexisting neoplastic and reactive giant cells. Pathol Int. 2009;59:91-7 pubmed publisher
    ..To the authors' knowledge there has been no previous report on this subject except for a single case mentioned in Rosen's Breast Pathology...
  56. Miura N, Aoyama R, Kitagawa W, Yamada H, Nishikawa K, Imai H. Proteinase 3-antineutrophil cytoplasmic antibody-(PR3-ANCA) positive necrotizing glomerulonephritis after restarting sulphasalazine treatment. Clin Nephrol. 2009;71:74-9 pubmed
    ..One month after steroid therapy, the pleural effusion disappeared, and PR3-ANCA titer normalized 3 months later. This case suggests that sulphasalazine can induce PR3-ANCA-positive necrotizing glomerulonephritis...
  57. Zheng L, Amano K, Iohara K, Ito M, Imabayashi K, Into T, et al. Matrix metalloproteinase-3 accelerates wound healing following dental pulp injury. Am J Pathol. 2009;175:1905-14 pubmed publisher
    ..These results provide suggestive evidence that MMP-3 released from endothelial cells and/or endothelial progenitor cells in injured pulp plays critical roles in angiogenesis and pulp wound healing. ..
  58. Nakashima A, Mori K, Kaneko Y, Hayashi N, Nagatsu T, Ota A. Phosphorylation of the N-terminal portion of tyrosine hydroxylase triggers proteasomal digestion of the enzyme. Biochem Biophys Res Commun. 2011;407:343-7 pubmed publisher
    ..These results suggest that the phosphorylation of the N-terminal portion of TH regulates the degradation of this enzyme by the ubiquitin-proteasome pathway. ..
  59. Ishida M, Kataoka T, Niwa K, Iwaki M, Zako M. Efficient penetration into aqueous humor by administration of oral and topical levofloxacin. J Ocul Pharmacol Ther. 2011;27:247-50 pubmed publisher
    ..0085). Our protocol to achieve high aqueous humor concentrations of levofloxacin may be favorable in preventing endophthalmitis after eye surgery. ..
  60. Yamamoto Suzuki Y, Sakurai Y, Fujimura Y, Matsumoto M, Hamako J, Kokubo T, et al. Identification and recombinant analysis of botrocetin-2, a snake venom cofactor for von Willebrand factor-induced platelet agglutination. Biochemistry. 2012;51:5329-38 pubmed
  61. Matsunaga S, Ikeda M, Kishi T, Fukuo Y, Aleksic B, Yoshimura R, et al. An evaluation of polymorphisms in casein kinase 1 delta and epsilon genes in major psychiatric disorders. Neurosci Lett. 2012;529:66-9 pubmed publisher
    ..21) and BD (P=0.53). These results do not support that genetic variation in CSNK1D and CSNK1E is a susceptibility factor for major psychiatric disorders in the Japanese population. ..
  62. Onodera K, Sugiura H, Yamada M, Koarai A, Fujino N, Yanagisawa S, et al. Decrease in an anti-ageing factor, growth differentiation factor 11, in chronic obstructive pulmonary disease. Thorax. 2017;72:893-904 pubmed publisher
    ..Daily GDF11 treatment attenuated cellular senescence and airspace enlargement in an elastase-induced mouse model of emphysema. The decrease in GDF11 may be involved in the cellular senescence observed in COPD. ..
  63. Higashiyama R, Ohnuma T, Takebayashi Y, Hanzawa R, Shibata N, Yamamori H, et al. Association of copy number polymorphisms at the promoter and translated region of COMT with Japanese patients with schizophrenia. Am J Med Genet B Neuropsychiatr Genet. 2016;171B:447-57 pubmed publisher
    ..57, P = 0.00025) were significantly associated with schizophrenia. Large and rare CNVs as well as low-frequency CNVs and relatively small CNVs, namely <30 kb in COMT, may be genetic risk factors for schizophrenia. ..
  64. Nagasaki H, Ito M, Yuasa H, Saito H, Fukase M, Hamada K, et al. Two novel mutations in the coding region for neurophysin-II associated with familial central diabetes insipidus. J Clin Endocrinol Metab. 1995;80:1352-6 pubmed
  65. Nishiyama O, Taniguchi H, Kondoh Y, Nishimura K, Suzuki R, Takagi K, et al. The effectiveness of the visual analogue scale 8 in measuring health-related quality of life for COPD patients. Respir Med. 2000;94:1192-9 pubmed
    ..The VAS8 is well-suited to assess HRQoL in COPD patients. Visual analogue scales are generally useful in measuring HRQoL in COPD patients, and the VAS8 is particularly beneficial because of its ease of use. ..
  66. Oda N, Nakai A, Fujiwara K, Imamura S, Fujita T, Hamagishi M, et al. Polymorphisms of the insulin gene among Japanese subjects. Metabolism. 2001;50:631-4 pubmed
    ..We have no evidence that any of the mutations that we found are the cause of diabetes. Thus, mutations in the insulin gene do not appear to be an important genetic factor contributing to the development of diabetes in this population. ..
  67. Shimada Y, Horiguchi M, Kojima Y, Suzuki H. Transparent irrigation cannula for bimanual lens cortex removal. J Cataract Refract Surg. 2002;28:221-3 pubmed
    ..The cannula allows visualization of the proximal cortex and provides ample inflow to maintain an inflated anterior chamber even at a high aspiration pressure...
  68. Kurahashi H, Inagaki H, Yamada K, Ohye T, Taniguchi M, Emanuel B, et al. Cruciform DNA structure underlies the etiology for palindrome-mediated human chromosomal translocations. J Biol Chem. 2004;279:35377-83 pubmed
    ..Our data imply that for human chromosomes, translocation susceptibility is mediated by PATRRs and likely results from their unstable conformation. ..
  69. Zhuo L, Kimata K. Structure and function of inter-alpha-trypsin inhibitor heavy chains. Connect Tissue Res. 2008;49:311-20 pubmed publisher
  70. Tanaka Kitajima N, Iwata N, Ando Y, Sakurai H, Iwami M, Tsuzuki K, et al. Acute retinal necrosis caused by herpes simplex virus type 2 in a 3-year-old Japanese boy. Eur J Pediatr. 2009;168:1125-8 pubmed publisher
    ..Pediatricians must be aware of this rare disease, which can affect individuals without a previous history of HSV even in a country with a low seroprevalence of HSV-2...
  71. Tahara T, Arisawa T, Shibata T, Nakamura M, Yamashita H, Yoshioka D, et al. Effect of polymorphisms in the 3'-untranslated region (3'-UTR) of VEGF gene on gastric pre-malignant condition. Anticancer Res. 2009;29:485-9 pubmed
    ..GA; 0.98 +/- 0.87 vs. 1.55 +/- 0.96, p = 0.026). The G1612A but not the C936T polymorphism of the VEGF gene is associated with gastric pre-malignant condition in older individuals. ..
  72. Kawashima K, Ikeda M, Kishi T, Kitajima T, Yamanouchi Y, Kinoshita Y, et al. BDNF is not associated with schizophrenia: data from a Japanese population study and meta-analysis. Schizophr Res. 2009;112:72-9 pubmed publisher
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    ..The new pancreas transplant program at Fujita Health University has provided excellent outcomes for patients with type 1 diabetes. ..
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    ..This pathway has been shown to activate RhoA and regulate gastrulation movements. We propose that xNET1 or a similar RhoGEF may mediate Dishevelled signaling to RhoA in the Wnt pathway. ..
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    ..0424), but this may be a result of type I error due to multiple testing. Our results suggest that complexin genes do not play a major role in schizophrenia in Japanese patients. ..
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    ..Although both LPR and GERD are caused by reflux of stomach contents, their clinical presentations and treatments differ...
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    ..This technique can also be adopted in other skull base surgeries, in which the importance of endoscopy is growing. ..