Experts and Doctors on cell movement in Aichi, Japan


Locale: Aichi, Japan
Topic: cell movement

Top Publications

  1. Iizuka Kogo A, Shimomura A, Senda T. Colocalization of APC and DLG at the tips of cellular protrusions in cultured epithelial cells and its dependency on cytoskeletons. Histochem Cell Biol. 2005;123:67-73 pubmed
    ..This colocalization suggests that DLG functions not only at the lateral cell-cell contact sites of polarized epithelial cells but also at the protrusions of non-polarized epithelial cells through the interaction with APC protein. ..
  2. Watanabe T, Noritake J, Kaibuchi K. Roles of IQGAP1 in cell polarization and migration. Novartis Found Symp. 2005;269:92-101; discussion 101-5, 223-30 pubmed
  3. Sawada M, Sawamoto K. Mechanisms of neurogenesis in the normal and injured adult brain. Keio J Med. 2013;62:13-28 pubmed
    ..Some of these findings were presented in the Kitazato Prize Lecture at Keio University School of Medicine in 2011. ..
  4. Ishida T, Ishii T, Inagaki A, Yano H, Komatsu H, Iida S, et al. Specific recruitment of CC chemokine receptor 4-positive regulatory T cells in Hodgkin lymphoma fosters immune privilege. Cancer Res. 2006;66:5716-22 pubmed
  5. Zheng L, Amano K, Iohara K, Ito M, Imabayashi K, Into T, et al. Matrix metalloproteinase-3 accelerates wound healing following dental pulp injury. Am J Pathol. 2009;175:1905-14 pubmed publisher
    ..These results provide suggestive evidence that MMP-3 released from endothelial cells and/or endothelial progenitor cells in injured pulp plays critical roles in angiogenesis and pulp wound healing. ..
  6. Uchinaka A, Kawaguchi N, Ban T, Hamada Y, Mori S, Maeno Y, et al. Evaluation of dermal wound healing activity of synthetic peptide SVVYGLR. Biochem Biophys Res Commun. 2017;491:714-720 pubmed publisher
    ..In conclusion, SV peptide has a beneficial function to promote wound healing by stimulating granulation via stimulating angiogenesis, cell migration, and the myofibroblastic differentiation of fibroblasts. ..
  7. Ota H, Hikita T, Nishioka T, Matsumoto M, Ito J, Asai N, et al. Proteomic analysis of Girdin-interacting proteins in migrating new neurons in the postnatal mouse brain. Biochem Biophys Res Commun. 2013;442:16-21 pubmed publisher
    ..Our results suggest that Girdin and Girdin-interacting proteins control neuronal migration by regulating actin and/or microtubule dynamics. ..
  8. Okada A, Yasui T, Fujii Y, Niimi K, Hamamoto S, Hirose M, et al. Renal macrophage migration and crystal phagocytosis via inflammatory-related gene expression during kidney stone formation and elimination in mice: Detection by association analysis of stone-related gene expression and microstructural observation. J Bone Miner Res. 2010;25:2701-11 pubmed publisher
    ..Such crystal-removing ability of macrophages through phagocytosis and digestion might become a new target for the prevention of stone formation...
  9. Itano N, Atsumi F, Sawai T, Yamada Y, Miyaishi O, Senga T, et al. Abnormal accumulation of hyaluronan matrix diminishes contact inhibition of cell growth and promotes cell migration. Proc Natl Acad Sci U S A. 2002;99:3609-14 pubmed
    ..Our observations suggest that hyaluronan and its matrix can modulate contact inhibition of cell growth and migration, and provide evidence for functional differences between hyaluronan synthesized by the different HAS proteins. ..

More Information


  1. Yoneda M, Hirokawa Y, Ohashi A, Uchida K, Kami D, Watanabe M, et al. RhoB enhances migration and MMP1 expression of prostate cancer DU145. Exp Mol Pathol. 2010;88:90-5 pubmed publisher
    ..This is the first report evaluating RhoB function and the downstream signaling events in prostate cancer cell. Our results indicate that RhoB promotes cell motility and invasion in a metastatic prostate cancer cell. ..
  2. Minobe S, Sakakibara A, Ohdachi T, Kanda R, Kimura M, Nakatani S, et al. Rac is involved in the interkinetic nuclear migration of cortical progenitor cells. Neurosci Res. 2009;63:294-301 pubmed
    ..Similar inhibitory effects were obtained by forced expression of a dominant-negative Rac1. These results suggest that Rac may play a role in interkinetic nuclear migration in the developing mouse brain. ..
  3. Sugita M, Kato S, Sugita G, Oshika T. Migration of lens epithelial cells through haptic root of single-piece acrylic-foldable intraocular lens. Am J Ophthalmol. 2004;137:377-9 pubmed
    ..To report a case of posterior capsule opacification after cataract surgery due to lens epithelial cell migration through the haptic root of a single-piece acrylic-foldable intraocular lens...
  4. Inaguma S, Kasai K, Ikeda H. GLI1 facilitates the migration and invasion of pancreatic cancer cells through MUC5AC-mediated attenuation of E-cadherin. Oncogene. 2011;30:714-23 pubmed publisher
    ..This evidence revealed a new aspect of GLI1 function in modulating E-cadherin/?-catenin-regulated cancer cell properties through the expression of a gel-forming mucin. ..
  5. Thang N, Yajima I, Kumasaka M, Ohnuma S, Yanagishita T, Hayashi R, et al. Barium promotes anchorage-independent growth and invasion of human HaCaT keratinocytes via activation of c-SRC kinase. PLoS ONE. 2011;6:e25636 pubmed publisher
  6. Enomoto A, Murakami H, Asai N, Morone N, Watanabe T, Kawai K, et al. Akt/PKB regulates actin organization and cell motility via Girdin/APE. Dev Cell. 2005;9:389-402 pubmed
    ..These findings suggest that Girdin is essential for the integrity of the actin cytoskeleton and cell migration and provide a direct link between Akt and cell motility. ..
  7. Hayashi H, Al Mamun A, Sakima M, Sato M. Activator of G-protein signaling 8 is involved in VEGF-mediated signal processing during angiogenesis. J Cell Sci. 2016;129:1210-22 pubmed publisher
    ..These data suggest a potential role for AGS8-Gβγ in VEGF signal processing. AGS8 might play a key role in tissue adaptation by regulating angiogenic events. ..
  8. Nishio Y, Fujino M, Cai S, Kitajima Y, Saito T, Tsumura H, et al. Impaired CD98 signaling protects against graft-versus-host disease by increasing regulatory T cells. Transpl Immunol. 2016;35:34-9 pubmed publisher
    ..These findings are expected to make it possible to develop novel approaches for the prevention of GvHD. ..
  9. Iioka H, Ueno N, Kinoshita N. Essential role of MARCKS in cortical actin dynamics during gastrulation movements. J Cell Biol. 2004;164:169-74 pubmed
    ..These findings show that MARCKS regulates the cortical actin formation that is requisite for dynamic morphogenetic movements. ..