Experts and Doctors on cell membrane in Kagoshima, Japan


Locale: Kagoshima, Japan
Topic: cell membrane

Top Publications

  1. Owatari S, Akune S, Komatsu M, Ikeda R, Firth S, Che X, et al. Copper-transporting P-type ATPase, ATP7A, confers multidrug resistance and its expression is related to resistance to SN-38 in clinical colon cancer. Cancer Res. 2007;67:4860-8 pubmed
    ..Thus, ATP7A confers resistance to various anticancer agents on cancer cells and might be a good index of drug resistance in clinical colon cancers. ..
  2. Matsuo M, Oogai Y, Kato F, Sugai M, Komatsuzawa H. Growth-phase dependence of susceptibility to antimicrobial peptides in Staphylococcus aureus. Microbiology. 2011;157:1786-97 pubmed publisher
    ..Furthermore, we found that the ability to sense antimicrobial peptides only functioned in the exponential phase. These results suggest that cell surface charge is tightly regulated during growth in S. aureus. ..
  3. Chen Z, Aoki S, Komatsu M, Ueda K, Sumizawa T, Furukawa T, et al. Reversal of drug resistance mediated by multidrug resistance protein (MRP) 1 by dual effects of agosterol A on MRP1 function. Int J Cancer. 2001;93:107-13 pubmed
    ..In addition, the capacity of AG-A to reduce cellular glutathione levels may contribute to the modulating activity of MRP1. ..
  4. Mukai M, Che X, Furukawa T, Sumizawa T, Aoki S, Ren X, et al. Reversal of the resistance to STI571 in human chronic myelogenous leukemia K562 cells. Cancer Sci. 2003;94:557-63 pubmed
    ..Furthermore, STI571 itself was a potent reversing agent for MDR in P-gp-expressing KB-G2 cells. ..
  5. Taharaguchi S, Kono Y, Ohta H, Takase K. Putative host cell receptor for fowl adenovirus detected in gizzard. J Vet Med Sci. 2007;69:1203-5 pubmed
    ..By using a virus overlay protein binding assay (VOPBA), a putative FAV binding protein of approximately 200 kDa expressed in the gizzard was detected. ..
  6. Yoshida A, Shigekuni M, Tanabe K, Fujita A. Nanoscale analysis reveals agonist-sensitive and heterogeneous pools of phosphatidylinositol 4-phosphate in the plasma membrane. Biochim Biophys Acta. 2016;1858:1298-305 pubmed publisher
  7. Arimura K, Arimura Y, Ng A, Sakoda S, Higuchi I. Muscle membrane excitability after exercise in thyrotoxic periodic paralysis and thyrotoxicosis without periodic paralysis. Muscle Nerve. 2007;36:784-8 pubmed
    ..Paralytic attacks in TPP patients are due primarily to a preexisting latent abnormal excitability of the muscle membrane, possibly genetic in origin. ..
  8. Tamaki H, Shimada A, Ito Y, Ohya M, Takase J, Miyashita M, et al. LPT1 encodes a membrane-bound O-acyltransferase involved in the acylation of lysophospholipids in the yeast Saccharomyces cerevisiae. J Biol Chem. 2007;282:34288-98 pubmed
    ..These results indicate that, in concert with Slc1, Lpt1 plays a central role in PA biosynthesis, which is essential for cell viability. ..
  9. Ozawa M. p120-independent modulation of E-cadherin adhesion activity by the membrane-proximal region of the cytoplasmic domain. J Biol Chem. 2003;278:46014-20 pubmed
    ..These results indicate that the membrane-proximal region determines the activity of these cadherin constructs but that p120 does not seem directly involved in the modulation of E-cadherin activity. ..

More Information


  1. Ohnishi T, Kakimoto K, Bandow K, Lowenstein C, Daikuhara Y, Matsuguchi T. Mature hepatocyte growth factor/scatter factor on the surface of human granulocytes is released by a mechanism involving activated factor Xa. J Immunol. 2006;176:6945-53 pubmed
    ..Thus, human granulocytes may function as a transporter of HGF in the peripheral blood, releasing HGF at the injured sites caused by blood coagulation, where HGF may promote tissue repair. ..
  2. Ishigami S, Ueno S, Arigami T, Arima H, Uchikado Y, Kita Y, et al. Clinical implication of CD166 expression in gastric cancer. J Surg Oncol. 2011;103:57-61 pubmed publisher
    ..5 months) had a significantly poorer outcome than CD166-negative group (median 25.7 months range 1.4-106 months) (P?<?0.05). Membranous CD166-positivity may contribute to one of the promising prognostic markers in gastric cancer. ..
  3. Shiozaki K, Takeshita K, Ikeda M, Ikeda A, Harasaki Y, Komatsu M, et al. Molecular cloning and biochemical characterization of two novel Neu3 sialidases, neu3a and neu3b, from medaka (Oryzias latipes). Biochimie. 2013;95:280-9 pubmed publisher
    ..These results and phylogenetic analysis suggested that the medaka neu3a is an evolutionally conserved sialidase with regard to enzymatic properties, whereas neu3b is likely to have originally evolved in medaka. ..