Experts and Doctors on cell line in Aichi, Japan

Summary

Locale: Aichi, Japan
Topic: cell line

Top Publications

  1. Koide N, Mu M, Hassan F, Islam S, Tumurkhuu G, Dagvadorj J, et al. Lipopolysaccharide enhances interferon-gamma-induced nitric oxide (NO) production in murine vascular endothelial cells via augmentation of interferon regulatory factor-1 activation. J Endotoxin Res. 2007;13:167-75 pubmed
    ..Therefore, it is proposed that LPS enhanced NO production in IFN-gamma-stimulated END-D cells via augmenting p38 MAPKmediated IRF-1 activation. ..
  2. Chakravortty D, Kato Y, Sugiyama T, Koide N, Mu M, Yoshida T, et al. The inhibitory action of sodium arsenite on lipopolysaccharide-induced nitric oxide production in RAW 267.4 macrophage cells: a role of Raf-1 in lipopolysaccharide signaling. J Immunol. 2001;166:2011-7 pubmed
  3. Hashimoto R, Nakazawa T, Tsurusaki Y, Yasuda Y, Nagayasu K, Matsumura K, et al. Whole-exome sequencing and neurite outgrowth analysis in autism spectrum disorder. J Hum Genet. 2016;61:199-206 pubmed publisher
  4. Iizuka Kogo A, Shimomura A, Senda T. Colocalization of APC and DLG at the tips of cellular protrusions in cultured epithelial cells and its dependency on cytoskeletons. Histochem Cell Biol. 2005;123:67-73 pubmed
    ..This colocalization suggests that DLG functions not only at the lateral cell-cell contact sites of polarized epithelial cells but also at the protrusions of non-polarized epithelial cells through the interaction with APC protein. ..
  5. Fukushima T, Hamada Y, Yamada H, Horii I. Changes of micro-RNA expression in rat liver treated by acetaminophen or carbon tetrachloride--regulating role of micro-RNA for RNA expression. J Toxicol Sci. 2007;32:401-9 pubmed
    ..Thus, our data suggest microRNAs have an important role for toxicological mechanism and we proposed that the changes in microRNA expression might be key molecules for toxicity expression. ..
  6. Murase A, Taniguchi Y, Tonai Kachi H, Nakao K, Takada J. In vitro pharmacological characterization of CJ-042794, a novel, potent, and selective prostaglandin EP(4) receptor antagonist. Life Sci. 2008;82:226-32 pubmed
    ..These results suggest that CJ-042794, a novel, potent, and selective EP(4) receptor antagonist, has excellent pharmacological properties that make it a useful tool for exploring the physiological role of EP(4) receptors. ..
  7. Fujita H, Shimizu K, Yamamoto Y, Ito A, Kamihira M, Nagamori E. Fabrication of scaffold-free contractile skeletal muscle tissue using magnetite-incorporated myogenic C2C12 cells. J Tissue Eng Regen Med. 2010;4:437-43 pubmed publisher
    ..The scaffold-free skeletal muscle tissue engineering technique presented in this study will be useful for regenerative medicine, drug screening or use as a bio-actuator. ..
  8. Sato S, Ito Y, Kondo M, Ohashi T, Ito S, Nakayama S, et al. Ion transport regulated by protease-activated receptor 2 in human airway Calu-3 epithelia. Br J Pharmacol. 2005;146:397-407 pubmed
    ..The two types of desensitization seem likely to have PKC-mediated downregulation of PC-PLC in common. ..
  9. Islam S, Hassan F, Tumurkhuu G, Dagvadorj J, Koide N, Naiki Y, et al. Bacterial lipopolysaccharide induces osteoclast formation in RAW 264.7 macrophage cells. Biochem Biophys Res Commun. 2007;360:346-51 pubmed
    ..7 cells. Inhibitors of NF-kappaB and stress activated protein kinase (SAPK/JNK) prevented the LPS-induced osteoclast formation. The detailed mechanism of LPS-induced osteoclast formation is discussed. ..

More Information

Publications69

  1. Yamamoto Suzuki Y, Sakurai Y, Fujimura Y, Matsumoto M, Hamako J, Kokubo T, et al. Identification and recombinant analysis of botrocetin-2, a snake venom cofactor for von Willebrand factor-induced platelet agglutination. Biochemistry. 2012;51:5329-38 pubmed
  2. Nakao N, Kurokawa T, Nonami T, Tumurkhuu G, Koide N, Yokochi T. Hydrogen peroxide induces the production of tumor necrosis factor-alpha in RAW 264.7 macrophage cells via activation of p38 and stress-activated protein kinase. Innate Immun. 2008;14:190-6 pubmed publisher
    ..Therefore, H( 2) O(2) was suggested to induce TNF-alpha production in macrophages via activating p38 and SAPK/JNK as oxidative stress-related signal pathways. ..
  3. Kikuchi A, Ohashi K, Sugie Y, Sugimoto H, Omura H. Pharmacological evaluation of a novel cannabinoid 2 (CB2) ligand, PF-03550096, in vitro and in vivo by using a rat model of visceral hypersensitivity. J Pharmacol Sci. 2008;106:219-24 pubmed
    ..These results indicate that PF-03550096 is a potent CB(2) agonist and possesses efficacy in a rat model of visceral hypersensitivity. ..
  4. Jia Y, Asai A, Sakabe I, Maruyama M. Rat monoclonal antibodies against new guanine nucleotide exchange factor, mouse Zizimin2. Hybridoma (Larchmt). 2010;29:205-9 pubmed publisher
    ..These MAbs should therefore be very useful tools for study of the characterization of the Zizimin2 protein and the understanding of the biological function of Zizimin2-mediated immunosenescence. ..
  5. Harada N, Yoshimura N, Honda S. Unique regulation of expression of human aromatase in the placenta. J Steroid Biochem Mol Biol. 2003;86:327-34 pubmed
    ..The results suggest that the mouse placenta might lack in the transcriptional elements or factors essential for the placenta-specific expression of human aromatase gene. ..
  6. Fujita H, Shimizu K, Nagamori E. Novel method for measuring active tension generation by C2C12 myotube using UV-crosslinked collagen film. Biotechnol Bioeng. 2010;106:482-9 pubmed publisher
    ..The increased amount of myotubes is possibly due to the suppressed atrophy of myotubes by enhanced expression of Bcl-2. ..
  7. Sashio T, Kume H, Takeda N, Asano T, Tsuji S, Kondo M, et al. Possible Involvement of Sphingosine-1-Phosphate/G(i)/RhoA pathways in adherence of eosinophils to pulmonary endothelium. Allergol Int. 2012;61:283-93 pubmed publisher
    ..S1P causes adherence of eosinophils to pulmonary endothelium via RhoA activation. S1P may act as a lipid mediator in asthma. The RhoA/Rho-kinase pathway may be a therapeutic target for preventing eosinophil infiltration to the airway. ..
  8. Yamada S, Niwa J, Ishigaki S, Takahashi M, Ito T, Sone J, et al. Archaeal proteasomes effectively degrade aggregation-prone proteins and reduce cellular toxicities in mammalian cells. J Biol Chem. 2006;281:23842-51 pubmed
    ..Our study showed that archaeal proteasomes can degrade aggregation-prone proteins whose toxic gain of function causes neurodegradation and reduce protein cellular toxicity. ..
  9. Okamoto N, Mizote K, Honda H, Saeki A, Watanabe Y, Yamaguchi Miyamoto T, et al. Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex. J Biol Chem. 2017;292:15378-15394 pubmed publisher
    ..We conclude that FNC-RED and its synthetic derivative represent a novel category of murine and human TLR4/MD-2 agonist. ..
  10. Mu M, Koide N, Hassan F, Islam S, Sugiyama T, Ito H, et al. A role of mitogen and stress-activated protein kinase 1/2 in survival of lipopolysaccharide-stimulated RAW 264.7 macrophages. FEMS Immunol Med Microbiol. 2005;43:277-86 pubmed
    ..RAW 264.7 cells transfected with the dominant-negative MSK1 clones underwent cell death in response to LPS. Hence, it was suggested that MSK1/2 might play a critical role in the survival of LPS-stimulated RAW 264.7 cells. ..
  11. Harada N, Ogawa H, Shozu M, Yamada K, Suhara K, Nishida E, et al. Biochemical and molecular genetic analyses on placental aromatase (P-450AROM) deficiency. J Biol Chem. 1992;267:4781-5 pubmed
    ..During the transient expression in COS-7 cells, the aromatase cDNA of the patient was found to produce a protein with a trace of activity. This is the first report of a genetic defect for aromatase deficiency. ..
  12. Konishi Y, Karnan S, Takahashi M, Ota A, Damdindorj L, Hosokawa Y, et al. A system for the measurement of gene targeting efficiency in human cell lines using an antibiotic resistance-GFP fusion gene. Biotechniques. 2012;53:141-52 pubmed publisher
    ..Thus, our HygR-5' EGFP reporter system will assist in the development of an efficient AAV-based gene targeting technology. ..
  13. Yamada K, Nomura N, Yamano A, Yamada Y, Wakamatsu N. Identification and characterization of splicing variants of PLEKHA5 (Plekha5) during brain development. Gene. 2012;492:270-5 pubmed publisher
    ..These results suggest that the S- to L-conversion of PLEKHA5 (Plekha5) may play an important role in brain development through association with specific phosphoinositides. ..
  14. Haque A, Noman A, Koide N, Odkhuu E, Naiki Y, Hashimoto S, et al. An ADP ribosylation factor-GTPase activating protein negatively regulates the production of proinflammatory mediators in response to lipopolysaccharide. Cancer Immunol Immunother. 2011;60:1439-46 pubmed publisher
    ..Taken together, ASAP1 was suggested to negatively regulate LPS-induced proinflammatory mediators production through down-regulating LPS signaling. The feedback function of ASAP1 in LPS-mediated inflammatory response is discussed. ..
  15. Nakanishi T, Kohno K, Ishiura M, Ohashi H, Uchida T. Complete nucleotide sequence and characterization of the 5'-flanking region of mammalian elongation factor 2 gene. J Biol Chem. 1988;263:6384-91 pubmed
  16. Shinozaki K, Maruyama K, Kume H, Kuzume H, Obata K. A novel brain gene, norbin, induced by treatment of tetraethylammonium in rat hippocampal slice and accompanied with neurite-outgrowth in neuro 2a cells. Biochem Biophys Res Commun. 1997;240:766-71 pubmed
    ..Since in the course of neural plasticity the formation of new synapses should occur, the neurite-outgrowth-related protein, norbin, might play an important role in neural plasticity. ..
  17. Tsutsui K, Manabe R, Yamada T, Nakano I, Oguri Y, Keene D, et al. ADAMTSL-6 is a novel extracellular matrix protein that binds to fibrillin-1 and promotes fibrillin-1 fibril formation. J Biol Chem. 2010;285:4870-82 pubmed publisher
    ..All together, these results indicated that ADAMTSL-6 is a novel microfibril-associated protein that binds directly to fibrillin-1 and promotes fibrillin-1 matrix assembly. ..
  18. Dagvadorj J, Naiki Y, Tumurkhuu G, Hassan F, Islam S, Koide N, et al. Interleukin-10 inhibits tumor necrosis factor-alpha production in lipopolysaccharide-stimulated RAW 264.7 cells through reduced MyD88 expression. Innate Immun. 2008;14:109-15 pubmed publisher
    ..Therefore, IL-10 was suggested to inhibit LPS-induced TNF-alpha production via reduced MyD88 expression. ..
  19. Nakatani M, Takehara Y, Sugino H, Matsumoto M, Hashimoto O, Hasegawa Y, et al. Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice. FASEB J. 2008;22:477-87 pubmed
    ..Muscle strength is also recovered in the mdx/FS I-I mice. These results indicate that myostatin blockade by FS I-I has a therapeutic potential for muscular dystrophy. ..
  20. Islam S, Hassan F, Tumurkhuu G, Ito H, Koide N, Mori I, et al. Lipopolysaccharide prevents apoptosis induced by brefeldin A, an endoplasmic reticulum stress agent, in RAW 264.7 cells. Biochem Biophys Res Commun. 2006;340:589-96 pubmed
    ..Therefore, LPS was suggested to diminish the stress of ER/Golgi complexes induced by brefeldin A and inhibit apoptosis. The preventive action of LPS on brefeldin A-induced apoptosis is discussed. ..
  21. Kamiya N, Watanabe H, Habuchi H, Takagi H, Shinomura T, Shimizu K, et al. Versican/PG-M regulates chondrogenesis as an extracellular matrix molecule crucial for mesenchymal condensation. J Biol Chem. 2006;281:2390-400 pubmed
    ..These results suggest that versican/PG-M is involved in positively regulating the formation of the mesenchymal matrix and the onset of chondrocyte differentiation through the attached chondroitin sulfate chains. ..
  22. Inagaki H, Ohye T, Kogo H, Yamada K, Kowa H, Shaikh T, et al. Palindromic AT-rich repeat in the NF1 gene is hypervariable in humans and evolutionarily conserved in primates. Hum Mutat. 2005;26:332-42 pubmed
    ..Although such palindromic regions are usually unstable and disappear rapidly due to deletion, the 17PATRR in the NF1 gene was stably conserved during evolution for reasons that are still unknown. ..
  23. Takeuchi K, Kawashima A, Nagafuchi A, Tsukita S. Structural diversity of band 4.1 superfamily members. J Cell Sci. 1994;107 ( Pt 7):1921-8 pubmed
    ..In this study, we describe the initial characterization of these new members and discuss the evolution of the band 4.1 superfamily. ..
  24. Fujiwara Y, Kubo Y. Functional roles of charged amino acid residues on the wall of the cytoplasmic pore of Kir2.1. J Gen Physiol. 2006;127:401-19 pubmed
  25. Noman A, Koide N, Iftakhar E Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, et al. Retinoblastoma protein-interacting zinc finger 1, a tumor suppressor, augments lipopolysaccharide-induced proinflammatory cytokine production via enhancing nuclear factor-kappaB activation. Cell Immunol. 2010;264:114-8 pubmed publisher
    ..Therefore, RIZ1 was suggested to augment LPS-induced NF-kappaB activation in collaboration with p53 and enhance the production of proinflammatory cytokines in response to LPS. ..
  26. Hirano M, Tanaka S, Asami O. Classification of polycyclic aromatic hydrocarbons based on mutagenicity in lung tissue through DNA microarray. Environ Toxicol. 2013;28:652-9 pubmed publisher
    ..This metabolic activation and DNA damage is induced in lung epithelium, and the mutagenicity of PAHs can be classified by DNA microarray expression profiles. ..
  27. Miura K, Titani K, Kurosawa Y, Kanai Y. Molecular cloning of nucleobindin, a novel DNA-binding protein that contains both a signal peptide and a leucine zipper structure. Biochem Biophys Res Commun. 1992;187:375-80 pubmed
    ..The amino acid sequences of Nuc are highly conserved between mouse and human. We discuss the possible role of Nuc in autoimmunity. ..
  28. Inada H, Izawa I, Nishizawa M, Fujita E, Kiyono T, Takahashi T, et al. Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD. J Cell Biol. 2001;155:415-26 pubmed
    ..These results indicate that K18 may sequester TRADD to attenuate interactions between TRADD and activated TNFR1 and moderate TNF-induced apoptosis in simple epithelial cells. ..
  29. Sugiura N, Shioiri T, Chiba M, Sato T, Narimatsu H, Kimata K, et al. Construction of a chondroitin sulfate library with defined structures and analysis of molecular interactions. J Biol Chem. 2012;287:43390-400 pubmed publisher
    ..Chemo-enzymatic synthesis enables the generation of CS chains of the desired lengths, compositions, and distinct structures, and the resulting library will be a useful tool for studies of CS functions. ..
  30. Matsui T, Hamako J, Matsushita T, Nakayama T, Fujimura Y, Titani K. Binding site on human von Willebrand factor of bitiscetin, a snake venom-derived platelet aggregation inducer. Biochemistry. 2002;41:7939-46 pubmed
    ..Bitiscetin and botrocetin might modulate VWF by binding to the homologous region of the A1 domain to induce a conformational change leading to an increased accessibility to platelet GPIb. ..
  31. Tsukamoto K, Deakin J, Graves J, Hashimoto K. Exceptionally high conservation of the MHC class I-related gene, MR1, among mammals. Immunogenetics. 2013;65:115-24 pubmed publisher
  32. Hossain E, Ota A, Karnan S, Damdindorj L, Takahashi M, Konishi Y, et al. Arsenic augments the uptake of oxidized LDL by upregulating the expression of lectin-like oxidized LDL receptor in mouse aortic endothelial cells. Toxicol Appl Pharmacol. 2013;273:651-8 pubmed publisher
  33. Nakamura T, Komiya M, Sone K, Hirose E, Gotoh N, Morii H, et al. Grit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adapter molecules. Mol Cell Biol. 2002;22:8721-34 pubmed
    ..These results suggest that Grit, a novel TrkA-interacting protein, regulates neurite outgrowth by modulating the Rho family of small GTPases. ..
  34. Badamtseren B, Odkhuu E, Koide N, Haque A, Naiki Y, Hashimoto S, et al. Thalidomide inhibits interferon-?-mediated nitric oxide production in mouse vascular endothelial cells. Cell Immunol. 2011;270:19-24 pubmed publisher
    ..A phosphatase inhibitor, sodium orthovanadate, abolished the inhibitory action of thalidomide. Therefore, thalidomide was suggested to inhibit IFN-?-induced NO production via impaired STAT1 phosphorylation. ..
  35. Uchinaka A, Kawaguchi N, Ban T, Hamada Y, Mori S, Maeno Y, et al. Evaluation of dermal wound healing activity of synthetic peptide SVVYGLR. Biochem Biophys Res Commun. 2017;491:714-720 pubmed publisher
    ..In conclusion, SV peptide has a beneficial function to promote wound healing by stimulating granulation via stimulating angiogenesis, cell migration, and the myofibroblastic differentiation of fibroblasts. ..
  36. Noguchi H, Xu G, Matsumoto S, Kaneto H, Kobayashi N, Bonner Weir S, et al. Induction of pancreatic stem/progenitor cells into insulin-producing cells by adenoviral-mediated gene transfer technology. Cell Transplant. 2006;15:929-38 pubmed
    ..These data suggest that the overexpression of transcription factors, especially NeuroD, facilitates pancreatic stem/progenitor cell differentiation into insulin-producing cells...
  37. Uekawa N, Terauchi K, Nishikimi A, Shimada J, Maruyama M. Expression of TARSH gene in MEFs senescence and its potential implication in human lung cancer. Biochem Biophys Res Commun. 2005;329:1031-8 pubmed
    ..Thus, TARSH presumably represents a trigger gene for evoking cellular senescence, which has also been suggested to be involved in the prevention of tumorigenesis. ..
  38. Khuda I, Koide N, Noman A, Dagvadorj J, Tumurkhuu G, Naiki Y, et al. Seladin-1 is a novel lipopolysaccharide (LPS)-responsive gene and inhibits the tumour necrosis factor-alpha production and osteoclast formation in response to LPS. Immunology. 2010;131:59-66 pubmed publisher
    ..Therefore, it was suggested that seladin-1 might be an LPS-responsible gene product and regulate the LPS-induced inflammatory response negatively. ..
  39. Hayashi Y, Kim K, Fujiwara H, Shimono C, Yamashita M, Sanzen N, et al. Identification and recombinant production of human laminin alpha4 subunit splice variants. Biochem Biophys Res Commun. 2002;299:498-504 pubmed
    ..Since both alpha4A and alpha4B transcripts were detected by RT-PCR in several human cell lines, these two isoforms of laminin-8 with differing cell-adhesive activities are present in the basement membranes of human tissues. ..
  40. Watanabe H, Shionyu M, Kimura T, Kimata K, Watanabe H. Splicing factor 3b subunit 4 binds BMPR-IA and inhibits osteochondral cell differentiation. J Biol Chem. 2007;282:20728-38 pubmed
    ..Taken together, these results suggest that SF3b4, known to be localized in the nucleus and involved in RNA splicing, binds BMPR-IA and specifically inhibits BMP-mediated osteochondral cell differentiation. ..
  41. Takahashi K, Adachi K, Yoshizaki K, Kunimoto S, Kalaria R, Watanabe A. Mutations in NOTCH3 cause the formation and retention of aggregates in the endoplasmic reticulum, leading to impaired cell proliferation. Hum Mol Genet. 2010;19:79-89 pubmed publisher
    ..It is also possible that the aggregate-prone property of mutant Notch3 contributes to a pathogenic mechanism underlying CADASIL. ..
  42. Koide N, Morikawa A, Ito H, Sugiyama T, Hassan F, Islam S, et al. Defective responsiveness of CD5+ B1 cells to lipopolysaccharide in cytokine production. J Endotoxin Res. 2006;12:346-51 pubmed
    ..Defective responsiveness of TH2.52 B1 cells to LPS in cytokine production might be responsible for the failure of IFN-beta production due to the lack of molecules participating in the MyD88-independent pathway. ..
  43. Itano N, Sawai T, Yoshida M, Lenas P, Yamada Y, Imagawa M, et al. Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties. J Biol Chem. 1999;274:25085-92 pubmed
    ..The occurrence of three HAS isoforms with such distinct enzymatic characteristics may provide the cells with flexibility in the control of hyaluronan biosynthesis and functions. ..
  44. Koide N, Naiki Y, Morikawa A, Tumurkhuu G, Dagvadorj J, Noman A, et al. Nystatin-induced nitric oxide production in mouse macrophage-like cell line RAW264.7. Microbiol Immunol. 2009;53:295-300 pubmed publisher
    ..The results suggest that a moderate concentration of nystatin induces NO production by Na-pump activation through the PI3 kinase/Akt/NF-kappaB pathway without affecting the condition of lipid rafts. ..
  45. Sakai K, Kimata K, Sato T, Gotoh M, Narimatsu H, Shinomiya K, et al. Chondroitin sulfate N-acetylgalactosaminyltransferase-1 plays a critical role in chondroitin sulfate synthesis in cartilage. J Biol Chem. 2007;282:4152-61 pubmed
    ..Our studies may lead to a new therapeutic intervention, ameliorating the outcome of cartilage degenerative diseases. ..
  46. Iftakhar E Khuda I, Koide N, Hassan F, Noman A, Dagvadorj J, Tumurkhuu G, et al. Novel mechanism of U18666A-induced tumour necrosis factor-alpha production in RAW 264.7 macrophage cells. Clin Exp Immunol. 2009;155:552-8 pubmed publisher
    ..A p38 inhibitor reduced U18666A-induced TNF-alpha production. Taken together, U18666A was suggested to induce TNF-alpha production in RAW 264.7 cells via free cholesterol accumulation-mediated ROS generation. ..
  47. Itano N, Atsumi F, Sawai T, Yamada Y, Miyaishi O, Senga T, et al. Abnormal accumulation of hyaluronan matrix diminishes contact inhibition of cell growth and promotes cell migration. Proc Natl Acad Sci U S A. 2002;99:3609-14 pubmed
    ..Our observations suggest that hyaluronan and its matrix can modulate contact inhibition of cell growth and migration, and provide evidence for functional differences between hyaluronan synthesized by the different HAS proteins. ..
  48. Feng G, Yamada M, Wongsawatkul O, Li C, Huang L, An J, et al. Role of naofen, a novel WD repeat-containing protein, in reducing nitric oxide-induced relaxation. Clin Exp Pharmacol Physiol. 2008;35:1447-53 pubmed publisher
    ..The findings reinforce the functional significance of naofen-N-terminal protein on rat vascular reactivity. ..
  49. Mizuochi T, Matthews T, Kato M, Hamako J, Titani K, Solomon J, et al. Diversity of oligosaccharide structures on the envelope glycoprotein gp 120 of human immunodeficiency virus 1 from the lymphoblastoid cell line H9. Presence of complex-type oligosaccharides with bisecting N-acetylglucosamine residues. J Biol Chem. 1990;265:8519-24 pubmed
    ..Since the glycosylation is the product of host cell glycosyltransferases, an even greater number of glycosylation variants of gp120 are predicted to arise from the heterogeneous cell populations harboring the virus in in vivo infection. ..
  50. Imai K, Yamada K, Tamura M, Ochiai K, Okamoto T. Reactivation of latent HIV-1 by a wide variety of butyric acid-producing bacteria. Cell Mol Life Sci. 2012;69:2583-92 pubmed publisher
  51. Kogo H, Kowa Sugiyama H, Yamada K, Bolor H, Tsutsumi M, Ohye T, et al. Screening of genes involved in chromosome segregation during meiosis I: toward the identification of genes responsible for infertility in humans. J Hum Genet. 2010;55:293-9 pubmed publisher
    ..These 726 candidates for human infertility genes might serve as a useful resource for next-generation sequencing combined with exon capture by microarray...
  52. Yamaguchi T, Goto H, Yokoyama T, Sillje H, Hanisch A, Uldschmid A, et al. Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis. J Cell Biol. 2005;171:431-6 pubmed
    ..Taken together, these results indicated a novel mechanism that Cdk1 regulated mitotic vimentin phosphorylation via not only a direct enzyme reaction but also Plk1 recruitment to vimentin. ..
  53. Suzuki Y, Nakayama K, Hashimoto N, Yazawa I. Proteolytic processing regulates pathological accumulation in dentatorubral-pallidoluysian atrophy. FEBS J. 2010;277:4873-87 pubmed publisher
    ..Collectively, these results suggest that the C-terminal fragment plays a principal role in the pathological accumulation of ATN1 in dentatorubral-pallidoluysian atrophy. ..
  54. Sato N, Funayama N, Nagafuchi A, Yonemura S, Tsukita S. A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites. J Cell Sci. 1992;103 ( Pt 1):131-43 pubmed
    ..We conclude that at least one of the members of the ezrin-radixin-moesin family is concentrated at specific regions where actin filaments are densely associated with plasma membranes. ..
  55. Shimada H, Ochi T, Imasato A, Morizane Y, Hori M, Ozaki H, et al. Gene expression profiling and functional assays of activated hepatic stellate cells suggest that myocardin has a role in activation. Liver Int. 2010;30:42-54 pubmed publisher
    ..This study demonstrates that myocardin is involved in the activation of HSC; myocardin may serve as a novel therapeutic target in the treatment of liver fibrosis. ..
  56. Zheng L, Iohara K, Ishikawa M, Into T, Takano Yamamoto T, Matsushita K, et al. Runx3 negatively regulates Osterix expression in dental pulp cells. Biochem J. 2007;405:69-75 pubmed
    ..These results demonstrate the transcriptional regulation of Osterix expression by Runx3 during differentiation of dental pulp cells into odontoblasts during tooth development. ..
  57. Sasaki J, Ishikawa K, Arita M, Taniguchi K. ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites. EMBO J. 2012;31:754-66 pubmed publisher
    ..These results indicate that a viral protein/ACBD3/PI4KB complex is formed to synthesize PI4P at the AiV RNA replication sites and plays an essential role in viral RNA replication. ..
  58. Mochizuki M, Tsuchie Y, Yamada N, Miyake Y, Osawa T. Effect of sesame lignans on TNF-alpha-induced expression of adhesion molecules in endothelial cells. Biosci Biotechnol Biochem. 2010;74:1539-44 pubmed
    ..This suggests, that sesaminol-6-catehcol suppresses the expression of CAMs, and may be an active component of sesame lignans...
  59. Noman A, Koide N, Iftakhar E Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, et al. Retinoblastoma protein-interacting zinc finger 1 (RIZ1) participates in RANKL-induced osteoclast formation via regulation of NFATc1 expression. Immunol Lett. 2010;131:166-9 pubmed publisher
    ..It was suggested that that RIZ1 might participate in RANKL-induced osteoclast formation through the regulation of NFATc1 expression. ..
  60. Matsumoto K, Shionyu M, Go M, Shimizu K, Shinomura T, Kimata K, et al. Distinct interaction of versican/PG-M with hyaluronan and link protein. J Biol Chem. 2003;278:41205-12 pubmed
    ..These results provide important insights into the mechanisms of formation of the proteoglycan aggregate and HA binding of molecules containing the link module. ..