Experts and Doctors on amino acid motifs in Hiroshima, Japan


Locale: Hiroshima, Japan
Topic: amino acid motifs

Top Publications

  1. Kobayashi J, Antoccia A, Tauchi H, Matsuura S, Komatsu K. NBS1 and its functional role in the DNA damage response. DNA Repair (Amst). 2004;3:855-61 pubmed
    ..This molecular link of NBS1 to ATM may explain the phenotypic similarity of NBS to A-T. ..
  2. Sakamoto S, Fujikawa Y, Tanaka N, Esaka M. Molecular cloning and characterization of L-galactose-1-phosphate phosphatase from tobacco (Nicotiana tabacum). Biosci Biotechnol Biochem. 2012;76:1155-62 pubmed
    ..The AsA contents of NtGPPase over expression lines were higher than those of empty lines at 13 d after subculture. This suggests that NtGPPase contributes slightly to AsA biosynthesis. ..
  3. Kobayashi M, Kishida S, Fukui A, Michiue T, Miyamoto Y, Okamoto T, et al. Nuclear localization of Duplin, a beta-catenin-binding protein, is essential for its inhibitory activity on the Wnt signaling pathway. J Biol Chem. 2002;277:5816-22 pubmed
    ..Moreover, Duplin has an additional activity of inhibiting the Wnt signaling pathway by affecting the downstream beta-catenin target genes. ..
  4. Suzuki H, Tashiro S, Hira S, Sun J, Yamazaki C, Zenke Y, et al. Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1. EMBO J. 2004;23:2544-53 pubmed
    ..This region functioned as a heme-regulated NES dependent on the exporter Crm1. These results extend the regulatory roles for heme in protein sorting, and suggest that Bach1 transduces metabolic activity into gene expression. ..
  5. Sugiyama S, Kishida S, Chayama K, Koyama S, Kikuchi A. Ubiquitin-interacting motifs of Epsin are involved in the regulation of insulin-dependent endocytosis. J Biochem. 2005;137:355-64 pubmed
    ..These results suggest that the UIM motifs of hEpsin interact with proteins modified with ubiquitin, and that the complex formation is involved in insulin-dependent receptor endocytosis. ..
  6. Irie T, Shimazu Y, Yoshida T, Sakaguchi T. The YLDL sequence within Sendai virus M protein is critical for budding of virus-like particles and interacts with Alix/AIP1 independently of C protein. J Virol. 2007;81:2263-73 pubmed publisher
    ..Our results suggest that the interaction of multiple viral proteins with Alix/AIP1 may enhance the efficiency of the utilization of cellular MVB sorting machinery for efficient SeV budding...
  7. Kumagai T, Kihara H, Watanabe W, Noda M, Matoba Y, Sugiyama M. A novel tyrosine-phosphorylated protein inhibiting the growth of Streptomyces cells. Biochem Biophys Res Commun. 2009;385:534-8 pubmed publisher
  8. Kim H, Kataoka M, Ishikawa K. Atomic resolution of the crystal structure of the hyperthermophilic family 12 endocellulase and stabilizing role of the DxDxDG calcium-binding motif in Pyrococcus furiosus. FEBS Lett. 2012;586:1009-13 pubmed publisher
    ..Additionally, we further determined that the thermostability of EGPf is maintained in part by the binding of Ca²? in a DxDxDG Ca²?-binding motif, atypical of most archaeal proteins...
  9. Hashimoto M, Kodera N, Tsunaka Y, Oda M, Tanimoto M, Ando T, et al. Phosphorylation-coupled intramolecular dynamics of unstructured regions in chromatin remodeler FACT. Biophys J. 2013;104:2222-34 pubmed publisher
    ..These data lead to the conclusion that the inhibitory effect of nucleosome binding is ascribed to the increase in the probability of encounter between HMG and the phosphorylated IDR. ..

More Information


  1. Kajimura J, Fujiwara T, Yamada S, Suzawa Y, Nishida T, Oyamada Y, et al. Identification and molecular characterization of an N-acetylmuramyl-L-alanine amidase Sle1 involved in cell separation of Staphylococcus aureus. Mol Microbiol. 2005;58:1087-101 pubmed publisher
    ..aureus uses two peptidoglycan hydrolases, Atl and Sle1, for cell separation. Unlike Atl, Sle1 is not directly involved in autolysis of S. aureus...
  2. Hikosaka A, Kobayashi T, Saito Y, Kawahara A. Evolution of the Xenopus piggyBac transposon family TxpB: domesticated and untamed strategies of transposon subfamilies. Mol Biol Evol. 2007;24:2648-56 pubmed publisher
    ..The present results support our viewpoint that some Uribo2 members are naturally active autonomous transposons, whereas Kobuta members may be domesticated by hosts...
  3. Irie T, Inoue M, Sakaguchi T. Significance of the YLDL motif in the M protein and Alix/AIP1 for Sendai virus budding in the context of virus infection. Virology. 2010;405:334-41 pubmed publisher
    ..The results indicate that the YLDL motif is essential for efficient budding in the context of virus infection and suggest involvement of Alix/AIP1 in SeV budding. ..