Experts and Doctors on zebrafish in Okazaki, Aichi, Japan

Summary

Locale: Okazaki, Aichi, Japan
Topic: zebrafish

Top Publications

  1. Hossain M, Iwasaki H, Okochi Y, Chahine M, Higashijima S, Nagayama K, et al. Enzyme domain affects the movement of the voltage sensor in ascidian and zebrafish voltage-sensing phosphatases. J Biol Chem. 2008;283:18248-59 pubmed publisher
    ..These results indicate that the movement of the VSD is influenced by the enzymatic state of the cytoplasmic domain, providing an important clue for understanding mechanisms of coupling between the VSD and its effector. ..
  2. Saito D, Tanaka M. Comparative aspects of gonadal sex differentiation in medaka: a conserved role of developing oocytes in sexual canalization. Sex Dev. 2009;3:99-107 pubmed publisher
    ..We propose the concept of canalization as a key to gaining a comprehensive understanding of gonadal sex differentiation. In this respect, the possible role of the male-determining gene DMY/dmrt1bY is also discussed. ..
  3. Katsu Y, Kubokawa K, Urushitani H, Iguchi T. Estrogen-dependent transactivation of amphioxus steroid hormone receptor via both estrogen and androgen response elements. Endocrinology. 2010;151:639-48 pubmed publisher
    ..These results highlight the importance of comparative experimental approaches for the evolutionary study of endocrine systems. ..
  4. Koshida S, Kishimoto Y, Ustumi H, Shimizu T, Furutani Seiki M, Kondoh H, et al. Integrinalpha5-dependent fibronectin accumulation for maintenance of somite boundaries in zebrafish embryos. Dev Cell. 2005;8:587-98 pubmed
  5. Kawamura A, Koshida S, Takada S. Activator-to-repressor conversion of T-box transcription factors by the Ripply family of Groucho/TLE-associated mediators. Mol Cell Biol. 2008;28:3236-44 pubmed publisher
    ..These results indicate that the intrinsic transcriptional property of T-box proteins is controlled by Ripply family proteins, which act as specific adaptors that recruit the global corepressor Groucho/TLE to T-box proteins. ..
  6. Yabe T, Takada S. Mesogenin causes embryonic mesoderm progenitors to differentiate during development of zebrafish tail somites. Dev Biol. 2012;370:213-22 pubmed publisher
    ..Based on these results, we speculate that msgn1 expression in association with that of ntl may allow the differentiation of progenitor cells to proceed during development of somites in the tail. ..
  7. Matsunaga W, Watanabe E. Habituation of medaka (Oryzias latipes) demonstrated by open-field testing. Behav Processes. 2010;85:142-50 pubmed publisher
    ..Thus, the data from this study will afford useful fundamental information for behavioral phenotyping of medaka and for elucidating cognitive phenotypes in animals. ..
  8. Hashiura T, Kimura E, Fujisawa S, Oikawa S, Nonaka S, Kurosaka D, et al. Live imaging of primary ocular vasculature formation in zebrafish. PLoS ONE. 2017;12:e0176456 pubmed publisher
    ..Furthermore, this new morphological information enables us to assess the entire process of the primary ocular vasculature formation, which will be useful for its precise understanding. ..
  9. Okigawa S, Mizoguchi T, Okano M, Tanaka H, Isoda M, Jiang Y, et al. Different combinations of Notch ligands and receptors regulate V2 interneuron progenitor proliferation and V2a/V2b cell fate determination. Dev Biol. 2014;391:196-206 pubmed publisher
    ..In conclusion, V2-IN cell progenitor proliferation and V2a/V2b cell fate determination involve signaling through different sets of Notch ligand-receptor combinations that occur concurrently during development in zebrafish. ..

More Information

Publications21

  1. Satou C, Kimura Y, Hirata H, Suster M, Kawakami K, Higashijima S. Transgenic tools to characterize neuronal properties of discrete populations of zebrafish neurons. Development. 2013;140:3927-31 pubmed publisher
  2. Kimura Y, Satou C, Fujioka S, Shoji W, Umeda K, Ishizuka T, et al. Hindbrain V2a neurons in the excitation of spinal locomotor circuits during zebrafish swimming. Curr Biol. 2013;23:843-9 pubmed publisher
    ..These results indicated that hindbrain reticulospinal V2a neurons play critical roles in providing excitation to the spinal locomotor circuits during swimming by providing both tonic and phasic inputs to the circuits. ..
  3. Chen Q, Takada R, Takada S. Loss of Porcupine impairs convergent extension during gastrulation in zebrafish. J Cell Sci. 2012;125:2224-34 pubmed publisher
    ..Thus, a decrease of Porcn activity does not equivalently affect trafficking and lipidation of different Wnt proteins in zebrafish embryos and in cultured mammalian cells. ..
  4. Satou C, Kimura Y, Higashijima S. Generation of multiple classes of V0 neurons in zebrafish spinal cord: progenitor heterogeneity and temporal control of neuronal diversity. J Neurosci. 2012;32:1771-83 pubmed publisher
    ..These results suggest that multiple types of V0 neurons are produced by two distinct mechanisms; from heterogeneous p0 progenitors and from the same p0 progenitor, but in a time-dependent manner. ..
  5. Tao H, Manak J, Sowers L, Mei X, Kiyonari H, Abe T, et al. Mutations in prickle orthologs cause seizures in flies, mice, and humans. Am J Hum Genet. 2011;88:138-49 pubmed publisher
    ..These results suggest that prickle mutations have caused seizures throughout evolution. ..
  6. Takahashi J, Ohbayashi A, Oginuma M, Saito D, Mochizuki A, Saga Y, et al. Analysis of Ripply1/2-deficient mouse embryos reveals a mechanism underlying the rostro-caudal patterning within a somite. Dev Biol. 2010;342:134-45 pubmed publisher
    ..We propose that the rostro-caudal pattern is established by dynamic interaction of Notch activity with two Mesp2 domains, which are defined in successive segmentation cycles by Notch, Tbx6 and Ripply1/2...
  7. Satou C, Kimura Y, Kohashi T, Horikawa K, Takeda H, Oda Y, et al. Functional role of a specialized class of spinal commissural inhibitory neurons during fast escapes in zebrafish. J Neurosci. 2009;29:6780-93 pubmed publisher
    ..This study illustrates (1) a clear example of the behavioral role of a specialized class of interneurons and (2) the capacity of the spinal circuits to filter descending commands and thereby produce the appropriate behavior. ..
  8. Kimura Y, Satou C, Higashijima S. V2a and V2b neurons are generated by the final divisions of pair-producing progenitors in the zebrafish spinal cord. Development. 2008;135:3001-5 pubmed publisher
    ..We report that the terminal division of pair-producing progenitor cells in vertebrate neurogenesis can reproducibly produce two distinct neurons through a mechanism that may not depend on the orientation of the division axis. ..
  9. Akanuma T, Koshida S, Kawamura A, Kishimoto Y, Takada S. Paf1 complex homologues are required for Notch-regulated transcription during somite segmentation. EMBO Rep. 2007;8:858-63 pubmed
    ..Therefore, zebrafish homologues of the yeast Paf1 complex seem to preferentially affect a subset of genes, including Notch-regulated genes, during embryogenesis. ..
  10. Zhou L, Wang D, Kobayashi T, Yano A, Paul Prasanth B, Suzuki A, et al. A novel type of P450c17 lacking the lyase activity is responsible for C21-steroid biosynthesis in the fish ovary and head kidney. Endocrinology. 2007;148:4282-91 pubmed publisher
  11. Kawamura A, Koshida S, Hijikata H, Ohbayashi A, Kondoh H, Takada S. Groucho-associated transcriptional repressor ripply1 is required for proper transition from the presomitic mesoderm to somites. Dev Cell. 2005;9:735-44 pubmed
    ..Thus, ripply1 plays dual roles in the transition from the PSM to somites: termination of the segmentation program in the PSM and maintenance of the rostrocaudal polarity. ..
  12. Kawamura A, Koshida S, Hijikata H, Sakaguchi T, Kondoh H, Takada S. Zebrafish hairy/enhancer of split protein links FGF signaling to cyclic gene expression in the periodic segmentation of somites. Genes Dev. 2005;19:1156-61 pubmed
    ..Furthermore, Her13.2 augments autorepression of her1 in association with Her1 protein. Therefore, FGF signaling appears to maintain the oscillation machinery by supplying a binding partner, Her13.2, for Her1. ..