Experts and Doctors on axons in Dublin, Leinster, Ireland
Locale: Dublin, Leinster, Ireland
Rünker A, Little G, Suto F, Fujisawa H, Mitchell K. Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points. Neural Dev. 2008;3:34 pubmed publisher
..They also suggest that Sema6A, which is strongly expressed by oligodendrocytes, may affect CST regeneration in adults. ..
Zarin A, Daly A, Hülsmeier J, Asadzadeh J, Labrador J. A GATA/homeodomain transcriptional code regulates axon guidance through the Unc-5 receptor. Development. 2012;139:1798-805 pubmed publisher
..Taken together, our data strongly suggests that the eve-grn transcriptional code controls axon guidance, in part, by regulating the level of unc-5 expression. ..
Little G, Lopez Bendito G, Rünker A, García N, Piñon M, Chedotal A, et al
. Specificity and plasticity of thalamocortical connections in Sema6A mutant mice. PLoS Biol. 2009;7:e98 pubmed publisher
..These findings emphasize the importance and specificity of cortical cues in establishing thalamocortical connectivity and the spectacular capacity of the early postnatal cortex for remapping initial sensory representations. ..
Fanous A, Zhao Z, van den Oord E, Maher B, Thiselton D, Bergen S, et al
. Association study of SNAP25 and schizophrenia in Irish family and case-control samples. Am J Med Genet B Neuropsychiatr Genet. 2010;153B:663-674 pubmed publisher
..Although we failed to replicate this in an independent sample, this gene should be further tested in other samples. ..
Zarin A, Asadzadeh J, Hokamp K, McCartney D, Yang L, Bashaw G, et al
. A transcription factor network coordinates attraction, repulsion, and adhesion combinatorially to control motor axon pathway selection. Neuron. 2014;81:1297-1311 pubmed publisher
..Finally, we show that a network of TFs, comprised of eve, zfh1, and grain, induces the expression of the Unc5 and Beaten-path guidance receptors and the Fasciclin 2 and Neuroglian adhesion molecules to guide individual dMN axons. ..