Experts and Doctors on cattle in Kalyani, West Bengal, India

Summary

Locale: Kalyani, West Bengal, India
Topic: cattle

Top Publications

  1. Chakraborti S, Mandal A, Das S, Chakraborti T. Inhibition of Na+/Ca2+ exchanger by peroxynitrite in microsomes of pulmonary smooth muscle: role of matrix metalloproteinase-2. Biochim Biophys Acta. 2004;1671:70-8 pubmed
  2. Mandal A, Chakraborti T, Choudhury R, Ghosh B, Ghosh A, Das S, et al. Role of MMP-2 in inhibiting Na+ dependent Ca2+ uptake by H2O2 in microsomes isolated from pulmonary smooth muscle. Mol Cell Biochem. 2005;270:79-87 pubmed
    ..Thus, one of the mechanisms by which H2O2 activates MMP-2 could be due to inactivation of TIMP-2 by the oxidant. The resulting activation of MMP-2 subsequently inhibits Na+ dependent Ca2+ uptake in the microsomes. ..
  3. Kar P, Chakraborti T, Samanta K, Chakraborti S. Submitochondrial localization of associated mu-calpain and calpastatin. Arch Biochem Biophys. 2008;470:176-86 pubmed
  4. Samanta K, Kar P, Chakraborti T, Chakraborti S. Calcium-dependent cleavage of the Na(+)/Ca(2+) exchanger by m-calpain in isolated endoplasmic reticulum. J Biochem. 2010;147:225-35 pubmed publisher
    ..Cleavage of NCX1 by m-calpain in the ER may be interpreted as the main cause of intracellular Ca(2+) overload in the smooth muscle, which could be important for the manifestation of pulmonary hypertension. ..
  5. Samanta K, Kar P, Chakraborti T, Shaikh S, Chakraborti S. Characteristic properties of endoplasmic reticulum membrane m-calpain, calpastatin and lumen m-calpain: a comparative study between membrane and lumen m-calpains. J Biochem. 2010;147:765-79 pubmed publisher
    ..6 and 4.7, respectively) and IC(50) (0.52 and 0.8 nM, respectively) values of 110 and 70 kDa calpastatins. For first time, we have determined the characteristic properties, regulation and functional activity of LCp in the ER lumen. ..
  6. Shaikh S, Samanta K, Kar P, Roy S, Chakraborti T, Chakraborti S. m-Calpain-mediated cleavage of Na+/Ca2+ exchanger-1 in caveolae vesicles isolated from pulmonary artery smooth muscle. Mol Cell Biochem. 2010;341:167-80 pubmed publisher
  7. Mandal M, Das S, Chakraborti T, Mandal A, Chakraborti S. Identification, purification and partial characterization of tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in bovine pulmonary artery smooth muscle. Mol Cell Biochem. 2003;254:145-55 pubmed
    ..It was also found to be inactive against the serine proteases trypsin and plasmin. The inhibitor was heat and acid resistant and it had the sensitivity to trypsin degradation and reduction-alkylation. ..
  8. Mandal M, Mandal A, Das S, Chakraborti T, Chakraborti S. Identification, purification and partial characterization of tissue inhibitor of matrix metalloproteinase-2 in bovine pulmonary artery smooth muscle. Mol Cell Biochem. 2003;254:275-87 pubmed
    ..Treatment of the inhibitor with hydrogen peroxide, superoxide generating system (hypoxanthine plus xanthine oxidase) and peroxynitrite inactivated the inhibitor. ..
  9. Das S, Mandal M, Chakraborti T, Mandal A, Chakraborti S. Isolation of MMP-2 from MMP-2/TIMP-2 complex: characterization of the complex and the free enzyme in pulmonary vascular smooth muscle plasma membrane. Biochim Biophys Acta. 2004;1674:158-74 pubmed
    ..We have also presented additional data indicating that the isolated preparation of 72-kDa gelatinase exhibited properties that are identical with MMP-2 obtained from different sources. ..

Scientific Experts

More Information

Publications14

  1. Kar P, Chakraborti T, Roy S, Choudhury R, Chakraborti S. Identification of calpastatin and mu-calpain and studies of their association in pulmonary smooth muscle mitochondria. Arch Biochem Biophys. 2007;466:290-9 pubmed
  2. Paul S, Pramanick K, Kundu S, Bandyopadhyay A, Mukherjee D. Involvement of PI3 kinase and MAP kinase in IGF-I- and insulin-induced oocyte maturation in Cyprinus carpio. Mol Cell Endocrinol. 2009;309:93-100 pubmed publisher
    ..Taken together, these results suggest that PI3 kinase is an initial component of the signal transduction pathway which precedes MAP kinase, and MPF activation during IGF-I- and b-insulin-induced oocyte maturation in C. carpio. ..
  3. Dey K, Roy S, Ghosh B, Chakraborti S. Role of protein kinase C in phospholemman mediated regulation of ???? isozyme of Na?/K?-ATPase in caveolae of pulmonary artery smooth muscle cells. Biochimie. 2012;94:991-1000 pubmed publisher
  4. Mandai M, Das S, Chakraborti T, Chakraborti S. Matrix metalloprotease 2-mediated activation of Ca(2+)-ATPase by superoxide radical (O2*-) in plasma membrane of bovine pulmonary vascular smooth muscle. Indian J Biochem Biophys. 2002;39:390-6 pubmed
    ..Adding pure bovine MMP-2 to the smooth muscle membrane suspension causes an increase in Ca(2+)-ATPase activity, but the pretreatment with TIMP-2 inhibits the increase in the enzyme activity. ..
  5. Roy S, Chakraborti T, Chowdhury A, Chakraborti S. Role of PKC-? in NF-?B-MT1-MMP-mediated activation of proMMP-2 by TNF-? in pulmonary artery smooth muscle cells. J Biochem. 2013;153:289-302 pubmed publisher