Experts and Doctors on calpain in Kalyani, West Bengal, India


Locale: Kalyani, West Bengal, India
Topic: calpain

Top Publications

  1. Kar P, Chakraborti T, Roy S, Choudhury R, Chakraborti S. Identification of calpastatin and mu-calpain and studies of their association in pulmonary smooth muscle mitochondria. Arch Biochem Biophys. 2007;466:290-9 pubmed
  2. Kar P, Chakraborti T, Samanta K, Chakraborti S. Submitochondrial localization of associated mu-calpain and calpastatin. Arch Biochem Biophys. 2008;470:176-86 pubmed
  3. Samanta K, Kar P, Chakraborti T, Chakraborti S. Calcium-dependent cleavage of the Na(+)/Ca(2+) exchanger by m-calpain in isolated endoplasmic reticulum. J Biochem. 2010;147:225-35 pubmed publisher
    ..Cleavage of NCX1 by m-calpain in the ER may be interpreted as the main cause of intracellular Ca(2+) overload in the smooth muscle, which could be important for the manifestation of pulmonary hypertension. ..
  4. Samanta K, Kar P, Chakraborti T, Shaikh S, Chakraborti S. Characteristic properties of endoplasmic reticulum membrane m-calpain, calpastatin and lumen m-calpain: a comparative study between membrane and lumen m-calpains. J Biochem. 2010;147:765-79 pubmed publisher
    ..6 and 4.7, respectively) and IC(50) (0.52 and 0.8 nM, respectively) values of 110 and 70 kDa calpastatins. For first time, we have determined the characteristic properties, regulation and functional activity of LCp in the ER lumen. ..
  5. Shaikh S, Samanta K, Kar P, Roy S, Chakraborti T, Chakraborti S. m-Calpain-mediated cleavage of Na+/Ca2+ exchanger-1 in caveolae vesicles isolated from pulmonary artery smooth muscle. Mol Cell Biochem. 2010;341:167-80 pubmed publisher
  6. Chakraborti S, Alam M, Paik D, Shaikh S, Chakraborti T. Implications of calpains in health and diseases. Indian J Biochem Biophys. 2012;49:316-28 pubmed
    ..Herein, we present a brief overview on some implications of calpains on human health and some diseases. ..

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