Experts and Doctors on animals in Kalyani, West Bengal, India


Locale: Kalyani, West Bengal, India
Topic: animals

Top Publications

  1. Chatterjee S, Verma S, Pandey P. Profiling conserved biological pathways in Autosomal Dominant Polycystic Kidney Disorder (ADPKD) to elucidate key transcriptomic alterations regulating cystogenesis: A cross-species meta-analysis approach. Gene. 2017;627:434-450 pubmed publisher
    ..Thus, further translational research is warranted focusing on developing a combinatorial therapeutic approach for ADPKD redressal. ..
  2. Samanta K, Kar P, Chakraborti T, Shaikh S, Chakraborti S. Characteristic properties of endoplasmic reticulum membrane m-calpain, calpastatin and lumen m-calpain: a comparative study between membrane and lumen m-calpains. J Biochem. 2010;147:765-79 pubmed publisher
    ..6 and 4.7, respectively) and IC(50) (0.52 and 0.8 nM, respectively) values of 110 and 70 kDa calpastatins. For first time, we have determined the characteristic properties, regulation and functional activity of LCp in the ER lumen. ..
  3. Banerjee A, Pathak S, Biswas S, Roy Karmakar S, Boujedaini N, Belon P, et al. Chelidonium majus 30C and 200C in induced hepato-toxicity in rats. Homeopathy. 2010;99:167-76 pubmed publisher
    ..Homeopathy is a popular form of complementary and alternative medicine and is used to treat for certain liver ailments...
  4. Patra S, Das T, Ghosh S, Sarkar D, Jana B. Cadmium tolerance and antibiotic resistance of Pseudomonas sp. isolated from water, sludge and fish raised in wastewater-fed tropical ponds. Indian J Exp Biol. 2010;48:383-93 pubmed
    ..However, the bacterium isolated from raw sewage, water and sediment of the anaerobic pond was resistant to seven out of ten antibiotics tested. ..
  5. Das J, Das S, Samadder A, Bhadra K, Khuda Bukhsh A. Poly (lactide-co-glycolide) encapsulated extract of Phytolacca decandra demonstrates better intervention against induced lung adenocarcinoma in mice and on A549 cells. Eur J Pharm Sci. 2012;47:313-24 pubmed publisher
    ..Thus, overall results suggest that nano-encapsulation of PD (NPD) increases drug bioavailability and thereby has a better chemo-preventive action against lung cancer in vivo and on A549 cells in vitro than that of PD...
  6. Mandai M, Das S, Chakraborti T, Chakraborti S. Matrix metalloprotease 2-mediated activation of Ca(2+)-ATPase by superoxide radical (O2*-) in plasma membrane of bovine pulmonary vascular smooth muscle. Indian J Biochem Biophys. 2002;39:390-6 pubmed
    ..Adding pure bovine MMP-2 to the smooth muscle membrane suspension causes an increase in Ca(2+)-ATPase activity, but the pretreatment with TIMP-2 inhibits the increase in the enzyme activity. ..
  7. Samadder A, Das J, Das S, Das D, De A, Bhadra K, et al. Dihydroxy-isosteviol methyl ester of Pulsatilla nigricans extract reduces arsenic-induced DNA damage in testis cells of male mice: its toxicity, drug-DNA interaction and signaling cascades. Zhong Xi Yi Jie He Xue Bao. 2012;10:1433-42 pubmed publisher
    ..To evaluate the ameliorative efficacy of dihydroxy-isosteviol methyl ester (DIME) of Pulsatilla nigricans extract in arsenic-induced DNA damage in testis cells of mice...
  8. Biswas S, Khuda Bukhsh A. Evaluation of protective potentials of a potentized homeopathic drug, Chelidonium majus, during azo dye induced hepatocarcinogenesis in mice. Indian J Exp Biol. 2004;42:698-714 pubmed
    ..The microdoses of Chelidonium having no visible ill effects of their own, may be strong candidates for use in delaying/protecting liver cancer...
  9. Surjyo B, Anisur K. Protective action of an anti-oxidant (L-Ascorbic acid) against genotoxicity and cytotoxicity in mice during p-DAB-induced hepatocarcinogenesis. Indian J Cancer. 2004;41:72-80 pubmed
    ..Therefore studies involving vitamin supplementation, particularly with those with anti-oxidant activity, in combating cancer have routinely been carried out in both in vivo and in vitro systems, but relatively much less in mice...

More Information


  1. Mandal M, Mandal A, Das S, Chakraborti T, Chakraborti S. Identification, purification and partial characterization of tissue inhibitor of matrix metalloproteinase-2 in bovine pulmonary artery smooth muscle. Mol Cell Biochem. 2003;254:275-87 pubmed
    ..Treatment of the inhibitor with hydrogen peroxide, superoxide generating system (hypoxanthine plus xanthine oxidase) and peroxynitrite inactivated the inhibitor. ..
  2. Roy S, Chakraborti T, Chowdhury A, Chakraborti S. Role of PKC-? in NF-?B-MT1-MMP-mediated activation of proMMP-2 by TNF-? in pulmonary artery smooth muscle cells. J Biochem. 2013;153:289-302 pubmed publisher
  3. Kundu S, Pramanick K, Paul S, Bandyopadhyay A, Mukherjee D. Expression of LH receptor in nonpregnant mouse endometrium: LH induction of 3?-HSD and de novo synthesis of progesterone. J Endocrinol. 2012;215:151-65 pubmed publisher
  4. Paul A, Das J, Das S, Samadder A, Khuda Bukhsh A. Poly (lactide-co-glycolide) nano-encapsulation of chelidonine, an active bioingredient of greater celandine (Chelidonium majus), enhances its ameliorative potential against cadmium induced oxidative stress and hepatic injury in mice. Environ Toxicol Pharmacol. 2013;36:937-47 pubmed publisher
    ..Expression pattern of certain inflammatory and apoptotic signal proteins also indicated better hepato-protective abilities of nano-chelidonine, making it a more suitable protective drug than chelidonine against cadmium toxicity in mice...
  5. Dey K, Roy S, Ghosh B, Chakraborti S. Role of protein kinase C in phospholemman mediated regulation of ???? isozyme of Na?/K?-ATPase in caveolae of pulmonary artery smooth muscle cells. Biochimie. 2012;94:991-1000 pubmed publisher
  6. Das S, Das J, Paul A, Samadder A, Khuda Bukhsh A. Apigenin, a bioactive flavonoid from Lycopodium clavatum, stimulates nucleotide excision repair genes to protect skin keratinocytes from ultraviolet B-induced reactive oxygen species and DNA damage. J Acupunct Meridian Stud. 2013;6:252-62 pubmed publisher
  7. Shaikh S, Samanta K, Kar P, Roy S, Chakraborti T, Chakraborti S. m-Calpain-mediated cleavage of Na+/Ca2+ exchanger-1 in caveolae vesicles isolated from pulmonary artery smooth muscle. Mol Cell Biochem. 2010;341:167-80 pubmed publisher
  8. Bhattacharyya S, Paul S, Dutta S, Boujedaini N, Khuda Bukhsh A. Anti-oncogenic potentials of a plant coumarin (7-hydroxy-6-methoxy coumarin) against 7,12-dimethylbenz [a] anthracene-induced skin papilloma in mice: the possible role of several key signal proteins. Zhong Xi Yi Jie He Xue Bao. 2010;8:645-54 pubmed
    ..In the present study, its in vivo effects have been evaluated in mice...
  9. Sahu C, Ghatak S. Effects of dimecron on developing chick embryo: malformations and other histopathological changes. Anat Histol Embryol. 2002;31:15-20 pubmed
    ..The liver and kidney were severely affected by the pesticide at both doses. Based upon these findings it may be concluded that dimecron does play a role in producing embryotoxicity at different stages of embryogenesis. ..
  10. Samanta K, Kar P, Chakraborti T, Chakraborti S. Calcium-dependent cleavage of the Na(+)/Ca(2+) exchanger by m-calpain in isolated endoplasmic reticulum. J Biochem. 2010;147:225-35 pubmed publisher
    ..Cleavage of NCX1 by m-calpain in the ER may be interpreted as the main cause of intracellular Ca(2+) overload in the smooth muscle, which could be important for the manifestation of pulmonary hypertension. ..
  11. Paul S, Pramanick K, Kundu S, Bandyopadhyay A, Mukherjee D. Involvement of PI3 kinase and MAP kinase in IGF-I- and insulin-induced oocyte maturation in Cyprinus carpio. Mol Cell Endocrinol. 2009;309:93-100 pubmed publisher
    ..Taken together, these results suggest that PI3 kinase is an initial component of the signal transduction pathway which precedes MAP kinase, and MPF activation during IGF-I- and b-insulin-induced oocyte maturation in C. carpio. ..
  12. Kar P, Chakraborti T, Samanta K, Chakraborti S. Submitochondrial localization of associated mu-calpain and calpastatin. Arch Biochem Biophys. 2008;470:176-86 pubmed
  13. Mandal A, Chakraborti T, Choudhury R, Ghosh B, Ghosh A, Das S, et al. Role of MMP-2 in inhibiting Na+ dependent Ca2+ uptake by H2O2 in microsomes isolated from pulmonary smooth muscle. Mol Cell Biochem. 2005;270:79-87 pubmed
    ..Thus, one of the mechanisms by which H2O2 activates MMP-2 could be due to inactivation of TIMP-2 by the oxidant. The resulting activation of MMP-2 subsequently inhibits Na+ dependent Ca2+ uptake in the microsomes. ..
  14. Das S, Mandal M, Chakraborti T, Mandal A, Chakraborti S. Isolation of MMP-2 from MMP-2/TIMP-2 complex: characterization of the complex and the free enzyme in pulmonary vascular smooth muscle plasma membrane. Biochim Biophys Acta. 2004;1674:158-74 pubmed
    ..We have also presented additional data indicating that the isolated preparation of 72-kDa gelatinase exhibited properties that are identical with MMP-2 obtained from different sources. ..
  15. Chakraborti S, Mandal A, Das S, Chakraborti T. Inhibition of Na+/Ca2+ exchanger by peroxynitrite in microsomes of pulmonary smooth muscle: role of matrix metalloproteinase-2. Biochim Biophys Acta. 2004;1671:70-8 pubmed
  16. Biswas S, Khuda Bukhsh A. Effect of a homeopathic drug, Chelidonium, in amelioration of p-DAB induced hepatocarcinogenesis in mice. BMC Complement Altern Med. 2002;2:4 pubmed
  17. Paul S, Mandal S, Bhattacharyya S, Boujedaini N, Khuda Bukhsh A. In vitro and in vivo studies demonstrate anticancer property of root extract of Polygala senega. J Acupunct Meridian Stud. 2010;3:188-96 pubmed publisher
    ..Therefore, results of both in vivo and in vitro studies scientifically validate its potential use as an anticancer agent, particularly against lung cancer, and provide important information potentially helpful in drug designing...
  18. Biswas M, Kar B, Bhattacharya S, Kumar R, Ghosh A, Haldar P. Antihyperglycemic activity and antioxidant role of Terminalia arjuna leaf in streptozotocin-induced diabetic rats. Pharm Biol. 2011;49:335-40 pubmed publisher
    ..Terminalia arjuna Roxb. (Combretaceae), commonly known as Arjuna, is a large tree grown throughout the Indian peninsula and used traditionally for several medicinal purposes...
  19. Biswas S, Bhattacharjee N, Khuda Bukhsh A. Efficacy of a plant extract (Chelidonium majus L.) in combating induced hepatocarcinogenesis in mice. Food Chem Toxicol. 2008;46:1474-87 pubmed publisher
    ..The results suggest anti-tumor, anti-genotoxic and hepato-protective effects of the plant extract, showing potentials for use in cancer therapy...
  20. Kar P, Chakraborti T, Roy S, Choudhury R, Chakraborti S. Identification of calpastatin and mu-calpain and studies of their association in pulmonary smooth muscle mitochondria. Arch Biochem Biophys. 2007;466:290-9 pubmed
  21. Guha B, Das J, Khuda Bukhsh A. Ameliorative effects of vitamin supplementation on ethyl methane sulphonate-induced genotoxicity in a fish, Anabas testudineus. Ecotoxicol Environ Saf. 2007;68:63-70 pubmed
    ..The results of this study can lead to future research for exploring if low doses of these vitamins may be useful in protecting fish from genotoxic damage on exposure to mutagenic agents in small confined/stagnant waters...
  22. Chakraborti S, Alam M, Paik D, Shaikh S, Chakraborti T. Implications of calpains in health and diseases. Indian J Biochem Biophys. 2012;49:316-28 pubmed
    ..Herein, we present a brief overview on some implications of calpains on human health and some diseases. ..
  23. Mandal M, Das S, Chakraborti T, Mandal A, Chakraborti S. Identification, purification and partial characterization of tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in bovine pulmonary artery smooth muscle. Mol Cell Biochem. 2003;254:145-55 pubmed
    ..It was also found to be inactive against the serine proteases trypsin and plasmin. The inhibitor was heat and acid resistant and it had the sensitivity to trypsin degradation and reduction-alkylation. ..