Experts and Doctors on humans in Crete, Greece

Summary

Locale: Crete, Greece
Topic: humans

Top Publications

  1. Chatzicostas C, Koutroubakis I, Tzardi M, Roussomoustakaki M, Prassopoulos P, Kouroumalis E. Colonic tuberculosis mimicking Crohn's disease: case report. BMC Gastroenterol. 2002;2:10 pubmed
    ..In conclusion, this case highlights the need for awareness of intestinal tuberculosis in the differential diagnosis of chronic intestinal disease ..
  2. Sarafidou T, Kahl C, Martinez Garay I, Mangelsdorf M, Gesk S, Baker E, et al. Folate-sensitive fragile site FRA10A is due to an expansion of a CGG repeat in a novel gene, FRA10AC1, encoding a nuclear protein. Genomics. 2004;84:69-81 pubmed
    ..Our data also suggest that in the heterozygous state FRA10A is likely a benign folate-sensitive fragile site...
  3. Papadaki H, Tsagournisakis M, Mastorodemos V, Pontikoglou C, Damianaki A, Pyrovolaki K, et al. Normal bone marrow hematopoietic stem cell reserves and normal stromal cell function support the use of autologous stem cell transplantation in patients with multiple sclerosis. Bone Marrow Transplant. 2005;36:1053-63 pubmed
    ..The low clonogenic potential of BM hematopoietic progenitors probably reflects the presence of activated T cells rather than an intrinsic defect. ..
  4. Koukidou M, Klinakis A, Reboulakis C, Zagoraiou L, Tavernarakis N, Livadaras I, et al. Germ line transformation of the olive fly Bactrocera oleae using a versatile transgenesis marker. Insect Mol Biol. 2006;15:95-103 pubmed
    ..The self-activating gene construct combined with transposase mRNA present a system with potential for transgenesis of very diverse species. ..
  5. Panagiotakis S, Soufla G, Baritaki S, Sourvinos G, Passam A, Zagoreos I, et al. Concurrent CMV and EBV DNAemia is significantly correlated with a delay in the response to HAART in treatment-naive HIV type 1-positive patients. AIDS Res Hum Retroviruses. 2007;23:10-8 pubmed
    ..068). Conclusively, CMV and EBV DNAemia may be poor prognostic factors for the response to HAART in treatment-naive HIV-1 patients. ..
  6. Porichis F, Morou A, Baritaki S, Spandidos D, Krambovitis E. Activation-induced cell death signalling in CD4+ T cells by staphylococcal enterotoxin A. Toxicol Lett. 2008;176:77-84 pubmed
    ..These findings suggest that SEA triggers a TCR-mediated AICD mechanism in CD4+ T cells, the intracellular signalling of which is probably modulated, at least, by YY1. ..
  7. Amanatidou V, Sourvinos G, Apostolakis S, Neonaki P, Tsilimigaki A, Krambovitis E, et al. RANTES promoter gene polymorphisms and susceptibility to severe respiratory syncytial virus-induced bronchiolitis. Pediatr Infect Dis J. 2008;27:38-42 pubmed
    ..Our results indicate an association between a common genotype with severe RSV infection. This observation supports the previously reported results indicating RANTES as an important mediator of RSV infection. ..
  8. Pallis A, Ring A, Fortpied C, Penninckx B, Van Nes M, Wedding U, et al. EORTC workshop on clinical trial methodology in older individuals with a diagnosis of solid tumors. Ann Oncol. 2011;22:1922-6 pubmed publisher
    ..The identification of proper clinical outcomes and the validation of geriatric screening tools are needed for conducting sound and comparable clinical trials. ..
  9. Bitsios P, Roussos P. Tolcapone, COMT polymorphisms and pharmacogenomic treatment of schizophrenia. Pharmacogenomics. 2011;12:559-66 pubmed publisher
    ..It will soon be understood if tolcapone represents one of the first hypothesis-driven, biology-based, genotype-specific, targeted treatments of cognitive and negative symptoms of schizophrenia. ..

More Information

Publications388 found, 100 shown here

  1. Seblová V, Myskova J, Hlaváčová J, Votypka J, Antoniou M, Volf P. Natural hybrid of Leishmania infantum/L. donovani: development in Phlebotomus tobbi, P. perniciosus and Lutzomyia longipalpis and comparison with non-hybrid strains differing in tissue tropism. Parasit Vectors. 2015;8:605 pubmed publisher
    ..donovani complex developed late-stage infections in natural L. infantum vectors, P. perniciosus and L. longipalpis and none of the parameters studied seem to be linked with different tropism of parasites in the vertebrate host. ..
  2. Chrysos E, Tzortzinis A, Tsiaoussis J, Athanasakis H, Vasssilakis J, Xynos E. Prospective randomized trial comparing Nissen to Nissen-Rossetti technique for laparoscopic fundoplication. Am J Surg. 2001;182:215-21 pubmed
  3. Mazokopakis E, Papadakis J, Papadomanolaki M, Batistakis A, Giannakopoulos T, Protopapadakis E, et al. Effects of 12 months treatment with L-selenomethionine on serum anti-TPO Levels in Patients with Hashimoto's thyroiditis. Thyroid. 2007;17:609-12 pubmed
    ..The extension of Se supplementation for 6 more months resulted in an additional 8% decrease, while the cessation caused a 4.8% increase, in the anti-TPO concentrations. ..
  4. Thymiakou E, Zannis V, Kardassis D. Physical and functional interactions between liver X receptor/retinoid X receptor and Sp1 modulate the transcriptional induction of the human ATP binding cassette transporter A1 gene by oxysterols and retinoids. Biochemistry. 2007;46:11473-83 pubmed
    ..Overall, the present study revealed a novel mechanism of regulation of the human ABCA1 transporter which involves synergistic interactions between oxysterol/retinoid-inducible hormone nuclear receptors and the transcription factor Sp1. ..
  5. Margioris A. Fatty acids and postprandial inflammation. Curr Opin Clin Nutr Metab Care. 2009;12:129-37 pubmed publisher
    ..In this review, we will summarize all experimental evidence suggesting that the two families of PUFA appear to have antagonistic effects on postprandial inflammation, n-3 PUFA being anti-inflammatory while n-6 PUFA proinflammatory. ..
  6. Perisinakis K, Papadakis A, Damilakis J. The effect of x-ray beam quality and geometry on radiation utilization efficiency in multidetector CT imaging. Med Phys. 2009;36:1258-66 pubmed
    ..05). Overbeaming strongly depends on the beam collimation and focal spot size, while the impact of beam quality on GE is less pronounced. Thin beam collimations are associated with a GE of as low as 30%. ..
  7. Kymionis G, Karavitaki A, Kounis G, Portaliou D, Yoo S, Pallikaris I. Management of pellucid marginal corneal degeneration with simultaneous customized photorefractive keratectomy and collagen crosslinking. J Cataract Refract Surg. 2009;35:1298-301 pubmed publisher
    ..Corneal topography revealed a significant improvement in both eyes. Despite the encouraging results, longer follow-up is necessary to confirm the stability of the results. ..
  8. Kondili E, Alexopoulou C, Xirouchaki N, Vaporidi K, Georgopoulos D. Estimation of inspiratory muscle pressure in critically ill patients. Intensive Care Med. 2010;36:648-55 pubmed publisher
    ..A signal generated from flow, volume and airway pressure may be used to provide breath-by-breath quantitative information of inspiratory muscle pressure. ..
  9. Samoutis G, Soteriades E, Stoffers H, Philalithis A, Delicha E, Lionis C. A pilot quality improvement intervention in patients with diabetes and hypertension in primary care settings of Cyprus. Fam Pract. 2010;27:263-70 pubmed publisher
    ..Future studies need to involve a broader number of practices and patient populations. ..
  10. Kolli S, Aslanides I. Safety and efficacy of collagen crosslinking for the treatment of keratoconus. Expert Opin Drug Saf. 2010;9:949-57 pubmed publisher
    ..Available data suggest that this treatment has high efficacy and is very safe and may represent the future standard treatment for progressive keratoconus. ..
  11. Nikoletopoulou V, Markaki M, Palikaras K, Tavernarakis N. Crosstalk between apoptosis, necrosis and autophagy. Biochim Biophys Acta. 2013;1833:3448-3459 pubmed publisher
    ..This article is part of a Special Section entitled: Cell Death Pathways. ..
  12. Sonnenschein van der Voort A, Arends L, de Jongste J, Annesi Maesano I, Arshad S, Barros H, et al. Preterm birth, infant weight gain, and childhood asthma risk: a meta-analysis of 147,000 European children. J Allergy Clin Immunol. 2014;133:1317-29 pubmed publisher
    ..01-1.27). Younger gestational age at birth and higher infant weight gain were associated with childhood asthma outcomes. The associations of lower birth weight with childhood asthma were largely explained by gestational age at birth. ..
  13. Chouvarda I, Babalis D, Papaioannou V, Maglaveras N, Georgopoulos D. Multiparametric modeling of the ineffective efforts in assisted ventilation within an ICU. Med Biol Eng Comput. 2016;54:441-51 pubmed publisher
    ..The proposed model shows good correlation (over 0.74) with the actual outputs, constituting an encouraging step toward understanding of ICU ventilation dynamic phenomena. ..
  14. Petsalaki E, Zachos G. Clks 1, 2 and 4 prevent chromatin breakage by regulating the Aurora B-dependent abscission checkpoint. Nat Commun. 2016;7:11451 pubmed publisher
    ..We propose that Clks 1, 2 and 4 impose the abscission checkpoint by phosphorylating Aurora B-S331 at the midbody. ..
  15. Matalliotakis M, Goulielmos G, Matalliotaki C, Trivli A, Matalliotakis I, Arici A. Endometriosis in Adolescent and Young Girls: Report on a Series of 55 Cases. J Pediatr Adolesc Gynecol. 2017;30:568-570 pubmed publisher
  16. Messaritakis I, Politaki E, Kotsakis A, Dermitzaki E, Koinis F, Lagoudaki E, et al. Phenotypic characterization of circulating tumor cells in the peripheral blood of patients with small cell lung cancer. PLoS ONE. 2017;12:e0181211 pubmed publisher
  17. Teleb M, Kuppast B, Spyridaki K, Liapakis G, Fahmy H. Synthesis of 2-imino and 2-hydrazono thiazolo[4,5-d]pyrimidines as corticotropin releasing factor (CRF) antagonists. Eur J Med Chem. 2017;138:900-908 pubmed publisher
    ..A lead compound was identified and further evaluated by measuring its effect on the inhibition of the agonist-stimulated accumulation of second messengers. ..
  18. Kourmouli N, Dialynas G, Petraki C, Pyrpasopoulou A, Singh P, Georgatos S, et al. Binding of heterochromatin protein 1 to the nuclear envelope is regulated by a soluble form of tubulin. J Biol Chem. 2001;276:13007-14 pubmed
    ..These observations provide a new example of "moonlighting," a process whereby multimeric proteins switch function when their aggregation state or localization is altered. ..
  19. Zeghichi S, Kallithraka S, Simopoulos A. Nutritional composition of molokhia (Corchorus olitorius) and stamnagathi (Cichorium spinosum). World Rev Nutr Diet. 2003;91:1-21 pubmed
  20. Tamiolakis D, Papadopoulos N, Lambropoulou M, Venizelos J, Verettas D, Tsikouras P, et al. Ber-H2 (CD30) immunohistochemical staining of human fetal tissues. Int J Biol Sci. 2005;1:135-40 pubmed
    ..CD30 antigen is of importance in cell development, and proliferation. It is also pathway-related to terminal differentiation in many fetal tissues and organs. ..
  21. Apostolakis S, Baritaki S, Krambovitis E, Spandidos D. Distribution of HIV/AIDS protective SDF1, CCR5 and CCR2 gene variants within Cretan population. J Clin Virol. 2005;34:310-4 pubmed
    ..Since this polymorphism is related with delayed progression from HIV infection to AIDS, it could be used for prognostic genotyping in HIV infected Cretan individuals. ..
  22. Kyrmizakis D, Drivas E, Kruger Krasagakis S, Hajiioannou I, Karatzanis A, Velegrakis G. Acute rhinosinusitis associated with Sweet's syndrome. J Otolaryngol. 2006;35:144-7 pubmed
  23. Stefanidou M, Antoniou M, Koutsopoulos A, Neofytou Y, Krasagakis K, Kruger Krasagakis S, et al. A rare case of leishmaniasis recidiva cutis evolving for 31 years caused by Leishmania tropica. Int J Dermatol. 2008;47:588-9 pubmed publisher
    ..Complete regression was achieved with meglumine antimoniate (Glucantime) given intramuscularly (15 mg Sb(V)/kg/day for 15 days) and cryosurgery with liquid nitrogen. No recurrence was noted during a 12-month follow-up period...
  24. Tsatsakis A, Zafiropoulos A, Tzatzarakis M, Tzanakakis G, Kafatos A. Relation of PON1 and CYP1A1 genetic polymorphisms to clinical findings in a cross-sectional study of a Greek rural population professionally exposed to pesticides. Toxicol Lett. 2009;186:66-72 pubmed publisher
  25. Zacharioudaki V, Androulidaki A, Arranz A, Vrentzos G, Margioris A, Tsatsanis C. Adiponectin promotes endotoxin tolerance in macrophages by inducing IRAK-M expression. J Immunol. 2009;182:6444-51 pubmed publisher
    ..In conclusion, our data demonstrate that IRAK-M is a major mediator of gAd-induced endotoxin tolerance in primary macrophages, expression of which depends on the activation of Tpl2/ERK and PI3K/Akt1 signaling pathways. ..
  26. Grentzelos M, Plainis S, Astyrakakis N, Diakonis V, Kymionis G, Kallinikos P, et al. Efficacy of 2 types of silicone hydrogel bandage contact lenses after photorefractive keratectomy. J Cataract Refract Surg. 2009;35:2103-8 pubmed publisher
    ..7% of the eyes in the lotrafilcon B group. There were no differences in corneal reepithelialization or subjective measurements after PRK between the 2 types of silicone hydrogel bandage contact lenses. ..
  27. Tzanakis N, Tsiligianni I, Siafakas N. Pulmonary involvement and allergic disorders in inflammatory bowel disease. World J Gastroenterol. 2010;16:299-305 pubmed
    ..The purpose of this review is to update clinicians on recent available literature and to discuss the need for a highly suspicious approach by clinicians. ..
  28. Zafiropoulos A, Linardakis M, Jansen E, Tsatsakis A, Kafatos A, Tzanakakis G. Paraoxonase 1 R/Q alleles are associated with differential accumulation of saturated versus 20:5n3 fatty acid in human adipose tissue. J Lipid Res. 2010;51:1991-2000 pubmed publisher
    ..Furthermore, a novel function is suggested for PON1 on the fatty acid composition in the adipose tissue through the positive association of the R allele with saturated fatty acid and of the Q allele with 20:5n3 fatty acid deposition. ..
  29. Konsolaki E, Astyrakaki E, Stefanakis G, Agouridakis P, Askitopoulou H. Cranial trauma in ancient Greece: from Homer to classical authors. J Craniomaxillofac Surg. 2010;38:549-53 pubmed publisher
    ..Most of these descriptions show that the ancient Greeks possessed very good knowledge of the anatomy of the head and neck region and also of the pathophysiological consequences of trauma in the region. ..
  30. Plainis S, Petratou D, Giannakopoulou T, Atchison D, Tsilimbaris M. Binocular summation improves performance to defocus-induced blur. Invest Ophthalmol Vis Sci. 2011;52:2784-9 pubmed publisher
    ..The increased binocular facilitation observed with retinal blur may be due to the activation of a larger population of neurons at close-to-threshold detection under binocular stimulation. ..
  31. Radojicic J, Zaravinos A, Vrekoussis T, Kafousi M, Spandidos D, Stathopoulos E. MicroRNA expression analysis in triple-negative (ER, PR and Her2/neu) breast cancer. Cell Cycle. 2011;10:507-17 pubmed
    ..miR-21, miR-210 and miR-221 expression plays a significant role in triple- negative primary breast cancers. ..
  32. Lasithiotaki I, Giannarakis I, Tsitoura E, Samara K, Margaritopoulos G, Choulaki C, et al. NLRP3 inflammasome expression in idiopathic pulmonary fibrosis and rheumatoid lung. Eur Respir J. 2016;47:910-8 pubmed publisher
    ..Taken together, our results suggest distinct inflammasome activation profiles between autoimmune and idiopathic lung fibrosis. ..
  33. Thermos K. Functional mapping of somatostatin receptors in the retina: a review. Vision Res. 2003;43:1805-15 pubmed
    ..The important role of somatostatin in retinal disease therapeutics is also discussed. ..
  34. Maraki S, Scoulica E, Alpantaki K, Dialynas M, Tselentis Y. Lymphocutaneous nocardiosis due to Nocardia brasiliensis. Diagn Microbiol Infect Dis. 2003;47:341-4 pubmed
    ..The identification of the isolate was confirmed by nucleotide sequence analysis of the 16S rRNA gene. ..
  35. Vlata Z, Porichis F, Tzanakakis G, Tsatsakis A, Krambovitis E. A study of zearalenone cytotoxicity on human peripheral blood mononuclear cells. Toxicol Lett. 2006;165:274-81 pubmed
    ..Expose of PBMC to 1microg/ml ZEA did not alter the viability of the cells. Our results suggest that high ZEA concentrations in the blood may well exert cytotoxic effects that merit further investigation. ..
  36. Pavlidis P, Poirazi P. Individualized markers optimize class prediction of microarray data. BMC Bioinformatics. 2006;7:345 pubmed
  37. Fragouli E, Eliopoulos E, Petraki E, Sidiropoulos P, Aksentijevich I, Galanakis E, et al. Familial Mediterranean Fever in Crete: a genetic and structural biological approach in a population of 'intermediate risk'. Clin Genet. 2008;73:152-9 pubmed publisher
    ..In this model, the 'flexible loops' of caspase-1 appear to have no access to some positions that have been previously associated with mild disease, suggesting that alternative pathogenic pathways leading to FMF need to be explored. ..
  38. Xirouchaki N, Kondili E, Vaporidi K, Xirouchakis G, Klimathianaki M, Gavriilidis G, et al. Proportional assist ventilation with load-adjustable gain factors in critically ill patients: comparison with pressure support. Intensive Care Med. 2008;34:2026-34 pubmed publisher
    ..Compared to PS, PAV+ increases the probability of remaining on spontaneous breathing, while it considerably reduces the incidence of patient-ventilator asynchronies. ..
  39. Katzoli P, Sakellaris G, Ergazaki M, Charissis G, Spandidos D, Sourvinos G. Detection of herpes viruses in children with acute appendicitis. J Clin Virol. 2009;44:282-6 pubmed publisher
  40. Mamoulakis D, Bitsori M, Galanakis E, Vazgiourakis V, Panierakis C, Goulielmos G. Intron 4 polymorphism of the endothelial nitric oxide synthase eNOS gene and early microangiopathy in type 1 diabetes. Int J Immunogenet. 2009;36:153-7 pubmed publisher
    ..Our findings suggest that a/b polymorphism of the intron 4 eNOS gene is not associated with early onset diabetic microangiopathy. ..
  41. Zervou M, Goulielmos G, Castro Giner F, Tosca A, Krueger Krasagakis S. STAT4 gene polymorphism is associated with psoriasis in the genetically homogeneous population of Crete, Greece. Hum Immunol. 2009;70:738-41 pubmed publisher
    ..045, odds ratio = 1.42, 95% confidence interval 1.01-2.00), thus concluding that the polymorphism examined is associated with the development of psoriasis in our population. ..
  42. Mazokopakis E, Karefilakis C, Starakis I. Q fever endocarditis. Infect Disord Drug Targets. 2010;10:27-31 pubmed
    ..The epidemiology, signs and symptoms, laboratory findings, diagnosis and treatment of Q fever endocarditis are presented in our review. ..
  43. Kymionis G, Kontadakis G, Agorogiannis G, Bennett M, Angelidou F. Descemet stripping automated endothelial keratoplasty combined with phacoemulsification in Chandler syndrome. Eur J Ophthalmol. 2011;21:495-7 pubmed publisher
    ..To report a case of Descemet stripping automated endothelial keratoplasty (DSAEK) in combination with phacoemulsification and implantation of intraocular lens (IOL) (triple procedure) in a patient with Chandler syndrome...
  44. Briassoulis G, Damjanovic S, Xekouki P, Lefebvre H, Stratakis C. The glucocorticoid receptor and its expression in the anterior pituitary and the adrenal cortex: a source of variation in hypothalamic-pituitary-adrenal axis function; implications for pituitary and adrenal tumors. Endocr Pract. 2011;17:941-8 pubmed publisher
    ..Particular attention was paid to interactions that may affect the interpretation of diagnostic testing of the HPA axis in patients with pituitary adenomas (Cushing disease) or adrenocortical tumors (Cushing syndrome). ..
  45. Pasparakis G, Manouras T, Argitis P, Vamvakaki M. Photodegradable polymers for biotechnological applications. Macromol Rapid Commun. 2012;33:183-98 pubmed publisher
    ..Novel photochemistries have been combined with controlled polymerization methods, which result in well-defined photodegradable materials that exhibit light mediated and often controlled fragmentation processes. ..
  46. Perdikakis E, Kehagias E, Tsetis D. Common and uncommon complications of totally implantable central venous ports: a pictorial essay. J Vasc Access. 2012;13:345-50 pubmed publisher
    ..The purpose of this study is to present the characteristic radiologic features of common and uncommon complications in totally implantable central venous ports...
  47. Tsirakis G, Pappa C, Spanoudakis M, Chochlakis D, Alegakis A, Psarakis F, et al. Clinical significance of sCD105 in angiogenesis and disease activity in multiple myeloma. Eur J Intern Med. 2012;23:368-73 pubmed publisher
    ..CD105 seems to play an important role in angiogenesis and tumor progression. Circulating levels of sCD105 could detect patients with more advanced disease and might help in evaluating the response to treatment. ..
  48. Kymionis G, Grentzelos M, Kounis G, Diakonis V, Limnopoulou A, Panagopoulou S. Combined transepithelial phototherapeutic keratectomy and corneal collagen cross-linking for progressive keratoconus. Ophthalmology. 2012;119:1777-84 pubmed publisher
  49. Bouloukaki I, Komninos I, Mermigkis C, Micheli K, Komninou M, Moniaki V, et al. Translation and validation of Berlin questionnaire in primary health care in Greece. BMC Pulm Med. 2013;13:6 pubmed publisher
    ..The findings of our study confirm that such screening tools should be used by primary care clinicians for OSAS prediction. ..
  50. Ioannou C, Kontopodis N, Georgakarakos E, Kehagias E, Metaxa E, Lioudaki S, et al. Routine use of an aortic balloon to resolve possible inflow stenosis induced by the inflatable ring fixation mechanism of the Ovation endograft. Radiol Med. 2016;121:882-889 pubmed
    ..Overall, the hemodynamic impact of this abnormality seems to be clinically insignificant at 1-month follow-up. ..
  51. Peraki I, Palis J, Mavrothalassitis G. The Ets2 Repressor Factor (Erf) Is Required for Effective Primitive and Definitive Hematopoiesis. Mol Cell Biol. 2017;37: pubmed publisher
    ..We conclude that Erf is required for both primitive and erythromyeloid progenitor waves of hematopoietic stem cell (HSC)-independent hematopoiesis as well as for the normal function of HSCs. ..
  52. Hadjipavlou A, Gaitanis I, Papadopoulos C, Katonis P, Kontakis G. Serratia spondylodiscitis after elective lumbar spine surgery: a report of two cases. Spine (Phila Pa 1976). 2002;27:E507-12 pubmed
    ..This report describes two cases of acute spondylodiscitis, caused by, complicating two different conditions: microdiscectomy for herniated nucleus pulposus and decompressing laminotomy for spinal stenosis...
  53. Manios E, Mavrakis H, Kanoupakis E, Kallergis E, Dermitzaki D, Kambouraki D, et al. Effects of amiodarone and diltiazem on persistent atrial fibrillation conversion and recurrence rates: a randomized controlled study. Cardiovasc Drugs Ther. 2003;17:31-9 pubmed
  54. Fullard J. The role of the platelet glycoprotein IIb/IIIa in thrombosis and haemostasis. Curr Pharm Des. 2004;10:1567-76 pubmed
    ..Due to its critical role in mediating platelet aggregate formation GPIIb/IIIa has become a primary target for the development of antithrombotic agents. ..
  55. Briassoulis G, Mavrikiou M, Margeli A, Lazaropoulou C, Natsi L, Papassotiriou I, et al. Circulating levels of KL-6 in acute respiratory distress syndrome sepsis or traumatic brain injury in critically ill children. Pediatr Pulmonol. 2006;41:790-5 pubmed
    ..Only in patients with ARDS, plasma KL-6 levels were higher in non-survivors than survivors (P < 0.03). Plasma KL-6 levels have possible prognostic significance and may provide a useful marker for ARDS in critically ill children. ..
  56. Lachanas V, Koutsopoulos A, Hajiioannou J, Bizaki A, Helidonis E, Bizakis J. Osteoid osteoma of the ethmoid bone associated with dacryocystitis. Head Face Med. 2006;2:23 pubmed
    ..Osteoid osteomas (OO) are small, benign osteoblastic lesions. Ethmoid bone OO has been very rarely reported so far...
  57. Pontikoglou C, Liapakis G, Pyrovolaki K, Papadakis M, Bux J, Eliopoulos G, et al. Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropenia. Exp Hematol. 2006;34:1312-22 pubmed
    ..We suggest that anemia in CIN patients displays overlapping pathophysiologic features with anemia of chronic disease. ..
  58. Kyrmizakis D, Karatzanis A, Bourolias C, Hadjiioannou J, Velegrakis G. Nonmicrosurgical reconstruction of the auricle after traumatic amputation due to human bite. Head Face Med. 2006;2:45 pubmed
    ..Replantation of a severed ear without microsurgery can be a safe alternative as long as a proper technique is selected...
  59. Bizakis J, Karatzanis A, Hajiioannou J, Bourolias C, Maganas E, Spanakis E, et al. Diagnosis and management of substernal goiter at the University of Crete. Surg Today. 2008;38:99-103 pubmed publisher
    ..A thorough preoperative evaluation including computed tomography scan of the neck and mediastinum, and an appropriate surgical technique ensure a positive outcome for most patients with an SSG...
  60. Zaravinos A, Bizakis J, Spandidos D. RKIP and BRAF aberrations in human nasal polyps and the adjacent turbinate mucosae. Cancer Lett. 2008;264:288-98 pubmed publisher
    ..RKIP could play an important role in the down-regulation of wild-type BRAF, serving thus as an endogenous inhibitor of the MAPK pathway in nasal polyps and their adjacent turbinate mucosa. ..
  61. Kanellou P, Zaravinos A, Zioga M, Stratigos A, Baritaki S, Soufla G, et al. Genomic instability, mutations and expression analysis of the tumour suppressor genes p14(ARF), p15(INK4b), p16(INK4a) and p53 in actinic keratosis. Cancer Lett. 2008;264:145-61 pubmed publisher
    ..The deregulation of the expression profiles of the CDKN2A, CDKN2B and p53 genes may, independently of mutations and LOH at 9p21, play a significant role in AK and progression of AK to SCC. ..
  62. Kourtis N, Tavernarakis N. Autophagy and cell death in model organisms. Cell Death Differ. 2009;16:21-30 pubmed publisher
    ..In this review, we survey current research in simple organisms, linking autophagy to cell death and discuss the complex interplay between autophagy, cell survival and cell death. ..
  63. Bertsias G, Nakou M, Choulaki C, Raptopoulou A, Papadimitraki E, Goulielmos G, et al. Genetic, immunologic, and immunohistochemical analysis of the programmed death 1/programmed death ligand 1 pathway in human systemic lupus erythematosus. Arthritis Rheum. 2009;60:207-18 pubmed publisher
    ..The expression of PD-1/PDL-1 in renal tissue and during AMLRs suggests an important role in regulating peripheral T cell tolerance. ..
  64. Lyronis I, Ploumis N, Vlahakis I, Charissis G. Acute scrotum -etiology, clinical presentation and seasonal variation. Indian J Pediatr. 2009;76:407-10 pubmed publisher
    ..The low temperatures during winter may account for the increased incidence of the torsion of both the spermatic cord torsion and the appendages. ..
  65. Apostolakis S, Vogiatzi K, Amanatidou V, Spandidos D. Interleukin 8 and cardiovascular disease. Cardiovasc Res. 2009;84:353-60 pubmed publisher
    ..In the present review, the available evidence regarding the role of IL-8 in cardiovascular disease is presented, and future perspectives are discussed. ..
  66. Detorakis E, Zaravinos A, Spandidos D. Growth factor expression in ophthalmic pterygia and normal conjunctiva. Int J Mol Med. 2010;25:513-6 pubmed
    ..VEGFA expression may have potential for use in the selective treatment of pterygium with anti-VEGFA agents. ..
  67. Kalogeraki A, Tzardi M, Papadakis M, Stathopoulos E, Kouroumalis E, Zoras O. Apoptosis and cell proliferation correlated with tumor grade in patients with ampullary carcinoma. Acta Cytol. 2010;54:39-42 pubmed
  68. Papadopoulou E, Sismani C, Christodoulou C, Ioannides M, Kalmanti M, Patsalis P. Phenotype-genotype correlation of a patient with a "balanced" translocation 9;15 and cryptic 9q34 duplication and 15q21q25 deletion. Am J Med Genet A. 2010;152A:1515-22 pubmed publisher
    ..We provide correlation between the clinical findings of our patient and the phenotype of the 9q34 duplication syndrome, the 15q21, and the 15q25 deletion syndromes. ..
  69. Eleftheriadou A, Koudounarakis E. Vestibular-evoked myogenic potentials eliciting: an overview. Eur Arch Otorhinolaryngol. 2011;268:331-9 pubmed publisher
    ..However, the new ocular VEMPs in response to bone conducted vibration seem to be of clinical importance for the evaluation of utricular function. Further research is needed to support its clinical usefulness. ..
  70. Papadaki H. Autoreactive T-lymphocytes are implicated in the pathogenesis of bone marrow failure in patients with systemic lupus erythematosus. Leuk Lymphoma. 2003;44:1301-7 pubmed
  71. Pelagiadis I, Dimitriou H, Kalmanti M. Biologic characteristics of mesenchymal stromal cells and their clinical applications in pediatric patients. J Pediatr Hematol Oncol. 2008;30:301-9 pubmed publisher
    ..Appropriate preclinical models, completion of ongoing and development of new clinical trials will establish the role of these cells in the treatment of both adult and pediatric patients. ..
  72. Xenidis N, Ignatiadis M, Apostolaki S, Perraki M, Kalbakis K, Agelaki S, et al. Cytokeratin-19 mRNA-positive circulating tumor cells after adjuvant chemotherapy in patients with early breast cancer. J Clin Oncol. 2009;27:2177-84 pubmed publisher
    ..001) and overall survival (P = .003). The detection of CK-19 mRNA-positive CTCs in the blood after adjuvant chemotherapy is an independent risk factor indicating the presence of chemotherapy-resistant residual disease. ..
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    ..Modulation of the immune response by plasmacytoid DCs might provide novel immune-based therapies in autoimmunity and transplantation. ..
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    ..059), longer TTP (5.3 vs. 3.2 months; p = 0.051) and significantly longer OS (18.7 vs. 9.7 months; p = 0.009). ERCC1 could have a role in refining prognosis and thus individualizing chemotherapy for advanced stage NSCLC. ..
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    ..These results implicate VEGF, FGF2, TGFB1, EGF and IGF1 in the development of both PCa and BPH, rendering them potential targets for disease detection, monitoring and therapy. ..
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    ..After normal sinus rhythm was restored the patient presented with complete remission to the pre-event values of all haemolysis indices...
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    ..There may be a correlation, due to embryological reasons, between the presence of nasolabial cysts and the presence of chronic dacryocystitis. Both can be corrected surgically, under the same anaesthesia, without visible scar formation. ..
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