Genomes and Genes
Experts and Doctors on saccharomyces cerevisiae proteins in Kaiserslautern, Rheinland Pfalz, Germany
Locale: Kaiserslautern, Rheinland Pfalz, Germany
Topic: saccharomyces cerevisiae proteins
- Klöppel C, Suzuki Y, Kojer K, Petrungaro C, Longen S, Fiedler S, et al. Mia40-dependent oxidation of cysteines in domain I of Ccs1 controls its distribution between mitochondria and the cytosol. Mol Biol Cell. 2011;22:3749-57 pubmed publisher..We propose a model in which the Mia40-mediated oxidative folding of domain I controls the cellular distribution of Ccs1 and, consequently, active Sod1. ..
- Weckbecker D, Longen S, Riemer J, Herrmann J. Atp23 biogenesis reveals a chaperone-like folding activity of Mia40 in the IMS of mitochondria. EMBO J. 2012;31:4348-58 pubmed publisher..Thus, Mia40 plays a much broader role in import and folding of polypeptides than previously expected and can serve as folding factor for proteins with complex disulphide patterns as well as for cysteine-free polypeptides. ..
- Prestele M, Vogel F, Reichert A, Herrmann J, Ott M. Mrpl36 is important for generation of assembly competent proteins during mitochondrial translation. Mol Biol Cell. 2009;20:2615-25 pubmed publisher..This important function seems to be carried out by a stabilizing activity of Mrpl36 on the interaction between large and small ribosomal subunits, which could influence accuracy of protein synthesis. ..
- Gruschke S, Gröne K, Heublein M, Hölz S, Israel L, Imhof A, et al. Proteins at the polypeptide tunnel exit of the yeast mitochondrial ribosome. J Biol Chem. 2010;285:19022-8 pubmed publisher..This unique architecture of the tunnel exit is presumably an adaptation of the translation system to the specific requirements of the organelle. ..
- Keil M, Bareth B, Woellhaf M, Peleh V, Prestele M, Rehling P, et al. Oxa1-ribosome complexes coordinate the assembly of cytochrome C oxidase in mitochondria. J Biol Chem. 2012;287:34484-93 pubmed publisher..This points to a role for Oxa1 in the spatial coordination of the ribosome with assembly factors that are critical for enzyme biogenesis. ..