Experts and Doctors on hydrogenase in Bochum, North Rhine Westphalia, Germany

Summary

Locale: Bochum, North Rhine Westphalia, Germany
Topic: hydrogenase

Top Publications

  1. de Hatten X, Cournia Z, Huc I, Smith J, Metzler Nolte N. Force-field development and molecular dynamics simulations of ferrocene-peptide conjugates as a scaffold for hydrogenase mimics. Chemistry. 2007;13:8139-52 pubmed
    ..The presented MD simulation results of metallocenes thereby provide a convincing validation of our proposal to use ferrocene-peptides as minimal enzyme mimics...
  2. Stripp S, Sanganas O, Happe T, Haumann M. The structure of the active site H-cluster of [FeFe] hydrogenase from the green alga Chlamydomonas reinhardtii studied by X-ray absorption spectroscopy. Biochemistry. 2009;48:5042-9 pubmed publisher
    ..g., to the binding of an exogenous CO at 2Fe(H) in CO-inhibited enzyme. Our XAS studies pave the way for the monitoring of atomic level structural changes at the H-cluster during H(2) catalysis...
  3. Winkler M, Kuhlgert S, Hippler M, Happe T. Characterization of the key step for light-driven hydrogen evolution in green algae. J Biol Chem. 2009;284:36620-7 pubmed publisher
    ..Mapping of relevant HydA1 and PetF residues constitutes an important basis for manipulating the physiological photosynthetic electron flow in favor of light-driven H(2) production. ..
  4. Czech I, Stripp S, Sanganas O, Leidel N, Happe T, Haumann M. The [FeFe]-hydrogenase maturation protein HydF contains a H-cluster like [4Fe4S]-2Fe site. FEBS Lett. 2011;585:225-30 pubmed publisher
    ..Presumably, only the 2Fe cluster is transferred from HydF to HydA1, thereby forming the active site...
  5. Philipps G, Krawietz D, Hemschemeier A, Happe T. A pyruvate formate lyase-deficient Chlamydomonas reinhardtii strain provides evidence for a link between fermentation and hydrogen production in green algae. Plant J. 2011;66:330-40 pubmed publisher
    ..This analysis shows that the PFL1 pathway has a significant impact on hydrogen metabolism in C. reinhardtii. ..
  6. Pape M, Lambertz C, Happe T, Hemschemeier A. Differential expression of the Chlamydomonas [FeFe]-hydrogenase-encoding HYDA1 gene is regulated by the copper response regulator1. Plant Physiol. 2012;159:1700-12 pubmed publisher
    ..Electrophoretic mobility shift assays showed that the CRR1 SBP domain binds to one of the GTAC cores in vitro. These combined results prove that CRR1 is involved in HYDA1 promoter activation...
  7. Noth J, Krawietz D, Hemschemeier A, Happe T. Pyruvate:ferredoxin oxidoreductase is coupled to light-independent hydrogen production in Chlamydomonas reinhardtii. J Biol Chem. 2013;288:4368-77 pubmed publisher
    ..reinhardtii PFR1 was also able to allow H(2) evolution in reaction mixtures containing Clostridium acetobutylicum 2[4Fe-4S]-ferredoxin and [Fe-Fe]-hydrogenase HYDA...
  8. Engelbrecht V, Rodríguez Maciá P, Esselborn J, Sawyer A, Hemschemeier A, Rüdiger O, et al. The structurally unique photosynthetic Chlorella variabilis NC64A hydrogenase does not interact with plant-type ferredoxins. Biochim Biophys Acta. 2017;1858:771-778 pubmed publisher
    ..In an electrochemical characterization, the enzyme exhibited features typical of bacterial [FeFe]-hydrogenases (e.g. minor anaerobic oxidative inactivation), as well as of algal enzymes (very high oxygen sensitivity). ..

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