Experts and Doctors on humans in Düsseldorf, Germany

Summary

Locale: Düsseldorf, Germany
Topic: humans

Top Publications

  1. Kempf K, Hector J, Strate T, Schwarzloh B, Rose B, Herder C, et al. Immune-mediated activation of the endocannabinoid system in visceral adipose tissue in obesity. Horm Metab Res. 2007;39:596-600 pubmed
    ..Our data show a strong association between adipose tissue inflammation and ECS activation in obesity, and indicate that a pro-inflammatory state may directly activate the ECS. ..
  2. Riedel N, van Kamp I, Köckler H, Scheiner J, Loerbroks A, Clasen T, et al. Cognitive-Motivational Determinants of Residents' Civic Engagement and Health (Inequities) in the Context of Noise Action Planning: A Conceptual Model. Int J Environ Res Public Health. 2017;14: pubmed publisher
    ..While building on existing frameworks, our conceptual model will be tested empirically in the next stage of our research process. ..
  3. Willenberg H, Haase M, Papewalis C, Schott M, Scherbaum W, Bornstein S. Corticotropin-releasing hormone receptor expression on normal and tumorous human adrenocortical cells. Neuroendocrinology. 2005;82:274-81 pubmed
    ..The data support the assertion of a direct action of CRH on human adrenocortical cells in addition to an intra-adrenal CRH receptor/adrenocorticotropin system. Enhanced CRH1R expression may be involved in adrenocortical tumorigenesis. ..
  4. D Urso D, Prior R, Greiner Petter R, Gabreëls Festen A, Muller H. Overloaded endoplasmic reticulum-Golgi compartments, a possible pathomechanism of peripheral neuropathies caused by mutations of the peripheral myelin protein PMP22. J Neurosci. 1998;18:731-40 pubmed
    ..We propose that impaired trafficking of mutated PMP22 affects Schwann cell physiology leading to myelin instability and loss. ..
  5. Knobbe C, Reifenberger J, Blaschke B, Reifenberger G. Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas. J Natl Cancer Inst. 2004;96:483-6 pubmed
    ..Thus, epigenetic downregulation of CTMP transcription is a common aberration in glioblastomas. ..
  6. Schipper J, Hoffmann T, Klenzner T, Wagenmann M. [Unsuccessful duraplasty technique or persisting/recanalized Sternberg's canal?]. Laryngorhinootologie. 2013;92:400-5 pubmed publisher
    ..The closure of this bony canal requires a modified surgical procedure such as sufficient padding of the bony canal and its sealing by a vascularized pedicle flap in contrast to the ordinary planar bony skull base defects...
  7. Sell H, Divoux A, Poitou C, Basdevant A, Bouillot J, Bedossa P, et al. Chemerin correlates with markers for fatty liver in morbidly obese patients and strongly decreases after weight loss induced by bariatric surgery. J Clin Endocrinol Metab. 2010;95:2892-6 pubmed publisher
    ..Chemerin plasma concentrations decreased after bariatric surgery. This study suggests that chemerin might mediate metabolic alterations in obesity, drastically improving after gastric bypass. ..
  8. Kempf K, Haltern G, Füth R, Herder C, Müller Scholze S, Gulker H, et al. Increased TNF-alpha and decreased TGF-beta expression in peripheral blood leukocytes after acute myocardial infarction. Horm Metab Res. 2006;38:346-51 pubmed
    ..Gene expression alterations indicate a sophisticated regulation of counteracting TNF-alpha and TGF-beta cytokine expression in peripheral blood leukocytes after AMI with bias towards a pro-inflammatory situation. ..
  9. Heuser M, Gabdoulline R, Löffeld P, Dobbernack V, Kreimeyer H, Pankratz M, et al. Individual outcome prediction for myelodysplastic syndrome (MDS) and secondary acute myeloid leukemia from MDS after allogeneic hematopoietic cell transplantation. Ann Hematol. 2017;96:1361-1372 pubmed publisher
    ..In summary, we propose to combine molecular, cytogenetic, and patient- and transplantation-associated risk factors into a comprehensive risk model to provide personalized predictions of outcome after alloHCT. ..
  10. Pham C, Hartmann R, Böhler P, Stork B, Wesselborg S, Lin W, et al. Callyspongiolide, a cytotoxic macrolide from the marine sponge Callyspongia sp. Org Lett. 2014;16:266-9 pubmed publisher
    ..Callyspongiolide showed strong cytotoxicity against human Jurkat J16 T and Ramos B lymphocytes. ..

Locale

Detail Information

Publications62

  1. Kempf K, Hector J, Strate T, Schwarzloh B, Rose B, Herder C, et al. Immune-mediated activation of the endocannabinoid system in visceral adipose tissue in obesity. Horm Metab Res. 2007;39:596-600 pubmed
    ..Our data show a strong association between adipose tissue inflammation and ECS activation in obesity, and indicate that a pro-inflammatory state may directly activate the ECS. ..
  2. Riedel N, van Kamp I, Köckler H, Scheiner J, Loerbroks A, Clasen T, et al. Cognitive-Motivational Determinants of Residents' Civic Engagement and Health (Inequities) in the Context of Noise Action Planning: A Conceptual Model. Int J Environ Res Public Health. 2017;14: pubmed publisher
    ..While building on existing frameworks, our conceptual model will be tested empirically in the next stage of our research process. ..
  3. Willenberg H, Haase M, Papewalis C, Schott M, Scherbaum W, Bornstein S. Corticotropin-releasing hormone receptor expression on normal and tumorous human adrenocortical cells. Neuroendocrinology. 2005;82:274-81 pubmed
    ..The data support the assertion of a direct action of CRH on human adrenocortical cells in addition to an intra-adrenal CRH receptor/adrenocorticotropin system. Enhanced CRH1R expression may be involved in adrenocortical tumorigenesis. ..
  4. D Urso D, Prior R, Greiner Petter R, Gabreëls Festen A, Muller H. Overloaded endoplasmic reticulum-Golgi compartments, a possible pathomechanism of peripheral neuropathies caused by mutations of the peripheral myelin protein PMP22. J Neurosci. 1998;18:731-40 pubmed
    ..We propose that impaired trafficking of mutated PMP22 affects Schwann cell physiology leading to myelin instability and loss. ..
  5. Knobbe C, Reifenberger J, Blaschke B, Reifenberger G. Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas. J Natl Cancer Inst. 2004;96:483-6 pubmed
    ..Thus, epigenetic downregulation of CTMP transcription is a common aberration in glioblastomas. ..
  6. Schipper J, Hoffmann T, Klenzner T, Wagenmann M. [Unsuccessful duraplasty technique or persisting/recanalized Sternberg's canal?]. Laryngorhinootologie. 2013;92:400-5 pubmed publisher
    ..The closure of this bony canal requires a modified surgical procedure such as sufficient padding of the bony canal and its sealing by a vascularized pedicle flap in contrast to the ordinary planar bony skull base defects...
  7. Sell H, Divoux A, Poitou C, Basdevant A, Bouillot J, Bedossa P, et al. Chemerin correlates with markers for fatty liver in morbidly obese patients and strongly decreases after weight loss induced by bariatric surgery. J Clin Endocrinol Metab. 2010;95:2892-6 pubmed publisher
    ..Chemerin plasma concentrations decreased after bariatric surgery. This study suggests that chemerin might mediate metabolic alterations in obesity, drastically improving after gastric bypass. ..
  8. Kempf K, Haltern G, Füth R, Herder C, Müller Scholze S, Gulker H, et al. Increased TNF-alpha and decreased TGF-beta expression in peripheral blood leukocytes after acute myocardial infarction. Horm Metab Res. 2006;38:346-51 pubmed
    ..Gene expression alterations indicate a sophisticated regulation of counteracting TNF-alpha and TGF-beta cytokine expression in peripheral blood leukocytes after AMI with bias towards a pro-inflammatory situation. ..
  9. Heuser M, Gabdoulline R, Löffeld P, Dobbernack V, Kreimeyer H, Pankratz M, et al. Individual outcome prediction for myelodysplastic syndrome (MDS) and secondary acute myeloid leukemia from MDS after allogeneic hematopoietic cell transplantation. Ann Hematol. 2017;96:1361-1372 pubmed publisher
    ..In summary, we propose to combine molecular, cytogenetic, and patient- and transplantation-associated risk factors into a comprehensive risk model to provide personalized predictions of outcome after alloHCT. ..
  10. Pham C, Hartmann R, Böhler P, Stork B, Wesselborg S, Lin W, et al. Callyspongiolide, a cytotoxic macrolide from the marine sponge Callyspongia sp. Org Lett. 2014;16:266-9 pubmed publisher
    ..Callyspongiolide showed strong cytotoxicity against human Jurkat J16 T and Ramos B lymphocytes. ..
  11. Sell H, Laurencikiene J, Taube A, Eckardt K, Cramer A, Horrighs A, et al. Chemerin is a novel adipocyte-derived factor inducing insulin resistance in primary human skeletal muscle cells. Diabetes. 2009;58:2731-40 pubmed publisher
    ..This study was aimed at investigating the regulation of chemerin release and its effects on glucose metabolism in skeletal muscle cells...
  12. Mühlfeld S, Domanova O, Berlage T, Stross C, Helmer A, Keitel V, et al. Short-term feedback regulation of bile salt uptake by bile salts in rodent liver. Hepatology. 2012;56:2387-97 pubmed publisher
    ..Phosphoinositide 3-kinase (PI3K) inhibitors had an additive effect, whereas Erk1/2 (extracellular signal activated kinase 1/2), p38MAPK, protein phosphatase 1/2A (PP1/2A), and reactive oxygen species (ROS) were not involved...
  13. Saure C, Warnke C, Zohren F, Schroeder T, Bruns I, Cadeddu R, et al. Natalizumab and impedance of the homing of CD34+ hematopoietic progenitors. Arch Neurol. 2011;68:1428-31 pubmed publisher
    ..Natalizumab mediates an increase in circulating CD34+ cells by interfering with homing to the BM. Thus, CD34+ cells appear unlikely to represent a source mobilizing JC virus out of the BM in patients treated with natalizumab. ..
  14. Ritz Timme S, Gabriel P, Tutkuviene J, Poppa P, Obertova Z, Gibelli D, et al. Metric and morphological assessment of facial features: a study on three European populations. Forensic Sci Int. 2011;207:239.e1-8 pubmed publisher
    ..The metric and morphological data collected from three European populations may be useful for forensic purposes in the construction of biological profiles and in screening for personal identification. ..
  15. Scheller J, Chalaris A, Schmidt Arras D, Rose John S. The pro- and anti-inflammatory properties of the cytokine interleukin-6. Biochim Biophys Acta. 2011;1813:878-88 pubmed publisher
    ..This article is part of a Special Issue entitled: 11th European Symposium on Calcium. ..
  16. Ewig S, Hoffken G, Kern W, Rohde G, Flick H, Krause R, et al. [Management of Adult Community-acquired Pneumonia and Prevention - Update 2016]. Pneumologie. 2016;70:151-200 pubmed publisher
    ..The guideline has a focus on specific clinical circumstances, an update on severity assessment, and includes recommendations for an individualized selection of antimicrobial treatment as well as primary and secondary prevention. ..
  17. Maney S, Xu H, Huang J, Pandyra A, Ehlting C, Aguilar Valenzuela R, et al. RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production. Cell Physiol Biochem. 2016;39:1271-80 pubmed publisher
    ..We have identified that the adaptor molecule RAIDD coordinates IKKε and IRF7 interaction to ensure efficient expression of type I interferon. ..
  18. Krieger V, Hamacher A, Gertzen C, Senger J, Zwinderman M, Marek M, et al. Design, Multicomponent Synthesis, and Anticancer Activity of a Focused Histone Deacetylase (HDAC) Inhibitor Library with Peptoid-Based Cap Groups. J Med Chem. 2017;60:5493-5506 pubmed publisher
    ..Furthermore, 4j almost completely reversed the cisplatin resistance in Cal27CisR. This effect is related to a synergistic induction of apoptosis as seen in the combination of 4j with cisplatin. ..
  19. Gwosdz C, Scheckenbach K, Lieven O, Reifenberger J, Knopf A, Bier H, et al. Comprehensive analysis of the p53 status in mucosal and cutaneous melanomas. Int J Cancer. 2006;118:577-82 pubmed
    ..Altogether, aberrant p53 expression appears to be a common event in both CM and MuM. ..
  20. Fritsche E, Schafer C, Calles C, Bernsmann T, Bernshausen T, Wurm M, et al. Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation. Proc Natl Acad Sci U S A. 2007;104:8851-6 pubmed
    ..The role of the AhR in the UVB stress response was confirmed in vivo by studies employing AhR KO mice. ..
  21. Mauss S, Borchard F, Jablonowski H, Niederau C. [HIV infection and the lower gastrointestinal tract--characteristics of endoscopic diagnosis]. Bildgebung. 1995;62:252-8 pubmed
    ..In combination with microbiological examination of stool specimen endoscopy of the lower gastrointestinal tract is a valuable diagnostic method, especially for the diagnosis of viral infections and neoplasm...
  22. van den Ecker D, van den Brand M, Ariaans G, Hoffmann M, Bossinger O, Mayatepek E, et al. Identification and functional analysis of mitochondrial complex I assembly factor homologues in C. elegans. Mitochondrion. 2012;12:399-405 pubmed publisher
    ..Our results suggest that mitochondrial complex I biogenesis is evolutionarily conserved. Moreover, Caenorhabditis elegans appears to be a promising model organism to study assembly factor related human diseases. ..
  23. Bara R, Zerfass I, Aly A, Goldbach Gecke H, Raghavan V, Sass P, et al. Atropisomeric dihydroanthracenones as inhibitors of multiresistant Staphylococcus aureus. J Med Chem. 2013;56:3257-72 pubmed publisher
    ..Notably, the compounds showed no cytotoxic activity, encouraging their further evaluation as potential starting points for antibacterial drug development...
  24. Lemaire L, Heinlein U. High-level expression in male germ cells of murine P68 RNA helicase mRNA. Life Sci. 1993;52:917-26 pubmed
    ..The signal was restricted to late pachytene spermatocytes and haploid spermatids. Northern blot analyses corroborated these results but suggested that expression of related mRNA species occurs in a variety of other tissues. ..
  25. Gorzelany K, Dursun A, Coskun T, Kalkanoğlu Sivri S, Gökçay G, Demirkol M, et al. Molecular genetics of maple syrup urine disease in the Turkish population. Turk J Pediatr. 2009;51:97-102 pubmed
    ..There was no cluster for a single mutation except for c.773G>A (p.Cys258Tyr) in the BCKDHA gene, a hypothetical founder mutation in the Camlidere population. ..
  26. Rezaei M, Emadi Baygi M, Hoffmann M, Schulz W, Nikpour P. Altered expression of LINC-ROR in cancer cell lines and tissues. Tumour Biol. 2016;37:1763-9 pubmed publisher
    ..Thus, we hypothesize that LINC-ROR may have a key function in a subpopulation of cells from the tumor bulk, i.e., the cancer stem cells associated with specific properties including resistance to adverse environmental conditions. ..
  27. Orgs G, Dombrowski J, Heil M, Jansen Osmann P. Expertise in dance modulates alpha/beta event-related desynchronization during action observation. Eur J Neurosci. 2008;27:3380-4 pubmed publisher
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  28. Herder C, Illig T, Baumert J, Müller M, Klopp N, Khuseyinova N, et al. Macrophage migration inhibitory factor (MIF) and risk for coronary heart disease: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002. Atherosclerosis. 2008;200:380-8 pubmed publisher
    ....
  29. Icks A, Haastert B, Rathmann W, Schröder Bernhardi D, Giani G. Cost comparison analysis: pentaerythrithyl tetranitrate (PETN) and isosorbide dinitrate (ISDN) prescribed to diabetic patients in primary care practices in Germany. Int J Clin Pharmacol Ther. 2007;45:516-23 pubmed
    ..Thus, the aim of this investigation was to compare the costs for PETN and ISDN therapy in diabetic patients in primary care...
  30. Sies H, Berndt C, Jones D. Oxidative Stress. Annu Rev Biochem. 2017;86:715-748 pubmed publisher
    ..This makes for a rich research field spanning from biochemistry and cell biology into nutritional sciences, environmental medicine, and molecular knowledge-based redox medicine. ..
  31. Dahlmann B, Kopp F, Kristensen P, Hendil K. Identical subunit topographies of human and yeast 20S proteasomes. Arch Biochem Biophys. 1999;363:296-300 pubmed
    ..Immunoelectron microscopy also showed that the C-terminal extension at the human C2 subunit is flexible but takes up a well-defined position in the proteasome. ..
  32. Gülden E, Märker T, Kriebel J, Kolb Bachofen V, Burkart V, Habich C. Heat shock protein 60: evidence for receptor-mediated induction of proinflammatory mediators during adipocyte differentiation. FEBS Lett. 2009;583:2877-81 pubmed publisher
    ..Our findings characterize Hsp60 binding and Hsp60-induced release of proinflammatory mediators as fundamental properties of adipocytes independent of their differentiation state. ..
  33. Möhlendick B, Bartenhagen C, Behrens B, Honisch E, Raba K, Knoefel W, et al. A robust method to analyze copy number alterations of less than 100 kb in single cells using oligonucleotide array CGH. PLoS ONE. 2013;8:e67031 pubmed publisher
    ....
  34. Feinendegen L, Hahnfeldt P, Schadt E, Stumpf M, Voit E. Systems biology and its potential role in radiobiology. Radiat Environ Biophys. 2008;47:5-23 pubmed
    ..In this context, we discuss in this article examples of relatively small, yet very useful models that elucidate selected aspects of the effects of exposure to ionizing radiation and may shine a light on the path before us. ..
  35. Schwarz F, John G, Mainusch S, Sahm N, Becker J. Combined surgical therapy of peri-implantitis evaluating two methods of surface debridement and decontamination. A two-year clinical follow up report. J Clin Periodontol. 2012;39:789-97 pubmed publisher
    ..The long-term stability of clinical outcomes obtained following combined surgical therapy of advanced peri-implantitis may be influenced by factors other than the method of surface debridement/decontamination. ..
  36. Rammos C, Hendgen Cotta U, Sobierajski J, Adamczyk S, Hetzel G, Kleophas W, et al. Macrophage migration inhibitory factor is associated with vascular dysfunction in patients with end-stage renal disease. Int J Cardiol. 2013;168:5249-56 pubmed publisher
    ..Further studies are necessary to investigate whether modulation of MIF might have an impact on atherosclerotic disease in this high-risk population. ..
  37. Schaefer K, Brachwitz K, Wai D, Braun Y, Diallo R, Korsching E, et al. Expression profiling of t(12;22) positive clear cell sarcoma of soft tissue cell lines reveals characteristic up-regulation of potential new marker genes including ERBB3. Cancer Res. 2004;64:3395-405 pubmed
    ..In conclusion, our data demonstrate new aspects of the phenotype and the biological behavior of CCSST and reveal ERBB3 to be a useful diagnostic marker...
  38. Rana O, Schröder J, Baukloh J, Saygili E, Mischke K, Schiefer J, et al. Neurofilament light chain as an early and sensitive predictor of long-term neurological outcome in patients after cardiac arrest. Int J Cardiol. 2013;168:1322-7 pubmed publisher
    ..92-1) on 5th and 0.99 (0.98-1) on 7th day was achieved for NF-L predicting poor neurological outcome. The present data suggest that within 7 days after cardiac arrest serum NF-L is a valuable marker of long-term neurological outcome. ..
  39. M nk C, Willemsen A, Bravo I. An ancient history of gene duplications, fusions and losses in the evolution of APOBEC3 mutators in mammals. BMC Evol Biol. 2012;12:71 pubmed publisher
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  40. Gripp S, Moeller S, Bölke E, Schmitt G, Matuschek C, Asgari S, et al. Survival prediction in terminally ill cancer patients by clinical estimates, laboratory tests, and self-rated anxiety and depression. J Clin Oncol. 2007;25:3313-20 pubmed
    ..This study revealed that physicians' survival estimates were unreliable, especially in the case of patients near death. Self-reported emotional distress and objective PFs may improve the accuracy of survival estimates. ..
  41. Sprangers M, Feldhahn N, Liedtke S, Jumaa H, Siebert R, MUSCHEN M. SLP65 deficiency results in perpetual V(D)J recombinase activity in pre-B-lymphoblastic leukemia and B-cell lymphoma cells. Oncogene. 2006;25:5180-6 pubmed
    ..We conclude that iterative V(H) gene rearrangement represents a frequent feature in B-lymphoid malignancy, which can be attributed to SLP65 deficiency in many cases. ..
  42. Albrecht U, Yang X, Asselta R, Keitel V, Tenchini M, Ludwig S, et al. Activation of NF-kappaB by IL-1beta blocks IL-6-induced sustained STAT3 activation and STAT3-dependent gene expression of the human gamma-fibrinogen gene. Cell Signal. 2007;19:1866-78 pubmed
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  43. Hanneken S, Rutten A, Pasternack S, Eigelshoven S, El Shabrawi Caelen L, Wenzel J, et al. Systematic mutation screening of KRT5 supports the hypothesis that Galli-Galli disease is a variant of Dowling-Degos disease. Br J Dermatol. 2010;163:197-200 pubmed publisher
    ....
  44. Spelsberg H, Sundmacher R. [Amniotic membrane transplantation and high-dose systemic cyclosporin A (Sandimmun optoral) for Mooren's ulcer]. Klin Monbl Augenheilkd. 2007;224:135-9 pubmed
    ..In order to maintain or restore as much visual function as possible, additional amniotic membrane surgery should be performed early enough in the course of the disease. ..
  45. Winterhalter M, Malinski P, Danzeisen O, Sixt S, Monaca E, Jüttner T, et al. Prospective observational study for perioperative volume replacement with 6% HES 130/0,42, 4% gelatin and 6% HES 200/0,5 in cardiac surgery. Eur J Med Res. 2010;15:383-9 pubmed
    ..The blood coagulation was mostly impaired due to HES 200/0.5 confirmed by the multiplate®-analysis as well as by different clinical findings. ..
  46. Schulz W, Ingenwerth M, Djuidje C, Hader C, Rahnenführer J, Engers R. Changes in cortical cytoskeletal and extracellular matrix gene expression in prostate cancer are related to oncogenic ERG deregulation. BMC Cancer. 2010;10:505 pubmed publisher
    ..We hypothesize that these alterations may contribute to the increased invasivity conferred to prostate cancer cells by ERG deregulation. ..
  47. Munk C, Jensen B, Zielonka J, Haussinger D, Kamp C. Running loose or getting lost: how HIV-1 counters and capitalizes on APOBEC3-induced mutagenesis through its Vif protein. Viruses. 2012;4:3132-61 pubmed publisher
    ..Both experimental evidence and the substantiation of the underlying dynamics through coevolutionary models are presented as complementary views of a coevolutionary arms race. ..
  48. Winterhalter S, Severing K, Stammen J, Maier A, Godehardt E, Joussen A. Does atovaquone prolong the disease-free interval of toxoplasmic retinochoroiditis?. Graefes Arch Clin Exp Ophthalmol. 2010;248:1187-92 pubmed publisher
    ..To evaluate the efficacy of suppressing a recurrence of Toxoplasma retinochoroiditis after treatment with atovaquone...
  49. Rose C, Karus C. Two sides of the same coin: sodium homeostasis and signaling in astrocytes under physiological and pathophysiological conditions. Glia. 2013;61:1191-205 pubmed publisher
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  50. Mortsiefer A, Meysen T, Schumacher M, Lintges C, Stamer M, Schmacke N, et al. CRISTOPH - a cluster-randomised intervention study to optimise the treatment of patients with hypertension in General Practice. BMC Fam Pract. 2008;9:33 pubmed publisher
    ..To our knowledge, no other published intervention study has yet evaluated the impact of educating GPs with the goal to treat patients with hypertension according to their global cardiovascular risk. ISRCTN44478543. ..
  51. Barski D, Wolter M, Reifenberger G, Riemenschneider M. Hypermethylation and transcriptional downregulation of the TIMP3 gene is associated with allelic loss on 22q12.3 and malignancy in meningiomas. Brain Pathol. 2010;20:623-31 pubmed publisher
    ....
  52. Esser C, Rannug A, Stockinger B. The aryl hydrocarbon receptor in immunity. Trends Immunol. 2009;30:447-54 pubmed publisher
    ..In particular, Th17 cells and dendritic cells express high levels of AhR. We review here current evidence for the physiological role of AhR in the immune system, focussing in particular on T-cell biology. ..
  53. Rieker J, Ruzicka T, Neumann N, Bielicky P, Homey B. [Type I and type IV sensitization to Asparagus officinalis]. Hautarzt. 2004;55:397-8 pubmed
    ..He also reported developing dyspnea and dysphagia after consuming asparagus. Diagnostic allergy testing revealed positive reactions against asparagus in prick-to-prick and epicutaneous patch tests...
  54. Grieb S, Korkmaz H, Reuter S, Bruch Gerharz D, Reifenberger J, Schulte K, et al. [Tuberculosis cutis colliquativa. Even today an important differential diagnosis]. Hautarzt. 2009;60:272-5 pubmed publisher
    ..Standard therapy regimens consist of 2 months of quadruple therapy followed by another 4 months of a continuation phase using a two-drug regimen...
  55. Maney S, McIlwain D, Polz R, Pandyra A, Sundaram B, Wolff D, et al. Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17. Sci Signal. 2015;8:ra109 pubmed publisher
    ....
  56. Brenneisen P, Blaudschun R, Gille J, Schneider L, Hinrichs R, Wlaschek M, et al. Essential role of an activator protein-2 (AP-2)/specificity protein 1 (Sp1) cluster in the UVB-mediated induction of the human vascular endothelial growth factor in HaCaT keratinocytes. Biochem J. 2003;369:341-9 pubmed
    ..In conclusion, our data clarified regulatory mechanisms of UVB-dependent VEGF stimulation which may be critical for angiogenic processes in the skin. ..
  57. Willenberg H, Path G, Vögeli T, Scherbaum W, Bornstein S. Role of interleukin-6 in stress response in normal and tumorous adrenal cells and during chronic inflammation. Ann N Y Acad Sci. 2002;966:304-14 pubmed
    ..We infer that the loss of responsivity of tumorous adrenal cells to IL-6, and in part corticotropin, is an important step in the process of adrenal tumorigenesis by which regulation by differentiating proteins is bypassed. ..
  58. Eberth A, Lundmark R, Gremer L, Dvorsky R, Koessmeier K, McMahon H, et al. A BAR domain-mediated autoinhibitory mechanism for RhoGAPs of the GRAF family. Biochem J. 2009;417:371-7 pubmed publisher
    ..Most remarkably, these BAR proteins represent a dual-site system with separate membrane-tubulation and GAP-inhibitory functions that operate simultaneously. ..
  59. Sagir A, Adams O, Oette M, Erhardt A, Heintges T, Haussinger D. SEN virus seroprevalence in HIV positive patients: association with immunosuppression and HIV-replication. J Clin Virol. 2005;33:183-7 pubmed
    ..The results were correlated with clinical markers such as HIV stage, CD4 cell count, HIV-RNA positivity, HAART or the transmission mode in HIV infected individuals...
  60. Wrehlke C, Wiedemeyer W, Schmitt Wrede H, Mincheva A, Lichter P, Wunderlich F. Genomic organization of mouse gene zfp162. DNA Cell Biol. 1999;18:419-28 pubmed
    ..The occurrence of PU.1/GRE supports the view that the zfp162 gene encodes a protein involved not only in nuclear RNA metabolism, as the human ZFM1/SF1, but also in as yet unknown macrophage-inherent functions. ..
  61. Bittersohl B, Miese F, Hosalkar H, Mamisch T, Antoch G, Krauspe R, et al. T2* mapping of acetabular and femoral hip joint cartilage at 3 T: a prospective controlled study. Invest Radiol. 2012;47:392-7 pubmed publisher
    ..The aim of this study was to identify the pattern of T2* values in acetabular and femoral head cartilage in morphologically normal and abnormal zones at 3 T...
  62. Stoeckel M, Pollok B, Witte O, Seitz R, Schnitzler A. Shrinkage of somatosensory hand area in subjects with upper extremity dysmelia revealed by magnetoencephalography. J Neurophysiol. 2005;93:813-8 pubmed
    ....